Abstract:
BACKGROUND AND PURPOSE:There have not been any new epidemiological studies related to stroke in Tibet for 20 years. This study aimed to collect stroke data from The City Staff Medical Insurance Registry in Lhasa, Tibet, to describe the incidence, clinical subtypes, and associated risk factors of stroke. METHODS:We used retrospective, population-based descriptive analysis of all urban and rural workers in the City Staff Medical Insurance Registry who were admitted to designated hospitals from October 2006 to October 2008. Stroke was defined by the International Classification of Disease (ICD)-10 coded from hospital records. RESULTS:Workers (81,298) were listed in the City Staff Medical Insurance Registry. Stroke patients (165) were included in the study, with 133 being first-ever patients. The age-standardized incidence rate was 88.725/100,000 per year (95% CI, 72.228-105.221), and mortality rate was 25.941/100,000 per year (95% CI, 16.416-35.466). The case fatality rate was 21.82%. Seventeen of the 133 patients (12.8%) were < 45 years of age. Stroke incidence rate was higher in ethnic Han patients than ethnic Tibetan patients. The most common subtype was cerebral infarction, and the most important risk factor was hypertension. CONCLUSIONS:Since the last study 20 years ago in Lhasa, stroke remains the primary fatal disease for the elderly, and its occurrence at younger ages is higher in Lhasa than in other areas of China. However, the annual incidence rate and mortality rate have decreased. The annual incidence rate is at a similar level to that in other parts of China. The primary subtype of stroke in Lhasa is cerebral ischemia.
journal_name
Strokejournal_title
Strokeauthors
Zhao Y,Yao Z,D'Souza W,Zhu C,Chun H,Zhuoga C,Zhang Q,Hu X,Zhou Ddoi
10.1161/STROKEAHA.110.586669subject
Has Abstractpub_date
2010-12-01 00:00:00pages
2739-43issue
12eissn
0039-2499issn
1524-4628pii
STROKEAHA.110.586669journal_volume
41pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:The *2 allele of the aldehyde dehydrogenase 2 gene (ALDH2) is the most common variant in Asian populations. The variant resulting in enzyme dysfunction was highly related to coronary artery disease. Recently, genome-wide association studies also discovered that the 12q24 locus near ALDH2 gene was...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.013204
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Carotid artery intima-media thickness (IMT) is a marker of cardiovascular disease associated with incident stroke. We studied whether IMT rate of change is associated with stroke. METHODS:We studied 5028 participants of the Multi-Ethnic Study of Atherosclerosis (MESA) comprising white, Chinese, ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.625186
更新日期:2011-11-01 00:00:00
abstract::Five patients studied by the authors and 28 mentioned in the literature indicate that recurrent stenosis occurs in no less than 0.6% of patients after carotid endarterectomy. The pathology of the recurrent stenosis was stated in only 10 cases indicating atherosclerotic disease in various stages of development in 7 and...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.8.5.597
更新日期:1977-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Within different brain regions, we determine the comparative value of multiphase computed tomographic angiography (mCTA) and computed tomographic perfusion (CTP) in predicting follow-up infarction. METHODS:Patients with M1-middle cerebral artery occlusions were prospectively included in this mul...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.116.015969
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke is the leading cause of adult disability worldwide. Currently, there is no effective treatment for stroke survivors. Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are the growth factors regulating hematopoiesis. We have previously observed that SCF and G-CSF have...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.486217
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Pial arterioles transiently dilate during cortical spreading depression (CSD), although the mechanisms are unclear. We tested the hypothesis that increased production of nitric oxide (NO) promotes arteriolar dilation. METHODS:Urethane-anesthetized rabbits were equipped with cranial windows, and ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.12.2463
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is controversy about the optimal patient position for the detection of right-to-left shunt (RLS). The study was performed to investigate which patient position best detects RLS during contrast-enhanced transcranial Doppler. METHODS:We prospectively evaluated consecutive patients with ische...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.609875
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/STROKEAHA.120.029454
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The effect of smoking reduction on cardiovascular disease outcomes has not been studied in Asian populations. METHODS:A total of 475 734 Korean men aged 30 to 58 years, stratified into 9 groups based on smoking status at 2 different time points (1990 and 1992), were followed from 1992 to 2001 fo...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.512632
更新日期:2008-09-01 00:00:00
abstract::Background and Purpose- Endovascular thrombectomy (ET) door-to-puncture time (DTPT) is a modifiable metric. One of the most important, yet time-consuming steps, is documentation of large vessel occlusion by computed tomography angiography (CTA). We hypothesized that obtaining CTA on board a Mobile Stroke Unit and dire...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.028626
更新日期:2020-05-01 00:00:00
abstract::The authors report an autopsy case with repeated transient ischemic attacks and subsequent strokes demonstrating evidence of artery-to-artery embolism from thrombi generated in the stenotic middle cerebral artery to the distal cortical branches. This case substantiates the existence of intracranial artery-to-artery em...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.3.680
更新日期:1987-05-01 00:00:00
abstract::Continuous-wave (CW) Doppler ultrasound imaging for prediction of arteriogrphic abnormality at the carotid bifurcation was carried out in 195 arteries of 105 patients. The Doppler method had no predictive value when compared to angiographic findings in arteries classified as 0-50% stenosis by Doppler. In 50-75% stenos...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.11.4.402
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of our study was to compare outcome and its determinants in familial subarachnoid hemorrhage and in sporadic subarachnoid hemorrhage in a large and well-documented patient population. METHODS:Patients with aneurysmal subarachnoid hemorrhage (SAH) treated at the Department of Neurosurgery...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.5.1099
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Ultrasonographic plaque echolucency has been studied as a stroke risk marker in carotid atherosclerotic disease. We performed a systematic review and meta-analysis to summarize the association between ultrasound-determined carotid plaque echolucency and future ipsilateral stroke risk. METHODS:We...
journal_title:Stroke
pub_type: 杂志文章,meta分析,评审
doi:10.1161/STROKEAHA.114.006091
更新日期:2015-01-01 00:00:00
abstract::Various studies indicate that after a latent interval, a progressive focal deterioration of microvascular perfusion can develop in zones of acute damage to the central nervous system (CNS). In order to obtain reliable information concerning the possibility of platelet participation in this phenomenon, platelet deposit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.16.2.224
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Treatment of stroke patients in specialized stroke units has become more frequent, yet the effect of this treatment has not been determined. METHODS:In a community-based, prospective, and consecutive study of 1241 unselected acute stroke patients, we compared outcome of stroke treatment between ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.7.1178
更新日期:1995-07-01 00:00:00
abstract::Changes of regional cerebral blood flow from rest to mental activation by a visually presented spatial reasoning test were measured during normo- and hypercapnia in 10 healthy subjects. Hypercapnia, elicited by inhalation of 6% CO2, resulted in similar flow increases in all 32 cortical regions measured. Increases of f...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.11.4.342
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Our objective was to study age-specific prevalence, computed tomographic (CT) characteristics, risk factors, and the prognostic influence on stroke outcome of silent infarction in acute stroke patients. METHODS:The study was prospective and community-based and included 801 acute stroke patients,...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.1.97
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The incidence of subarachnoid hemorrhage (SAH) has been investigated in many studies. A recent study in Izumo, Japan, indicates that the incidence of SAH is as high as that in Finland. The purpose of this study was to confirm the high incidence of SAH in Japan. METHODS:The incidence rate of SAH ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/hs0102.101891
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The natural history of stroke is worse in women than in men. Controversial data have been published on the efficacy of thrombolysis with recombinant tissue plasminogen activator (rtPA) according to gender. We evaluated gender differences in the efficacy and safety outcomes of intravenous rtPA usi...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/STROKEAHA.108.546325
更新日期:2009-06-01 00:00:00
abstract::Recent clinical studies emphasize the importance of early (less than 12 hours after onset) treatment of patients with acute ischemic stroke. Therapies have been proposed as being effective because of early clinical improvement. The frequency and degree of spontaneous improvement in such patients, however, is unknown. ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.7.1008
更新日期:1990-07-01 00:00:00
abstract::We report two patients with mixed transcortical aphasia following left frontal lobe infarctions. Although there was no evidence of anatomic isolation of the speech area on computed tomograms or magnetic resonance imaging scans, single-photon emission computed tomography in one case demonstrated diminished blood flow o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.6.953
更新日期:1990-06-01 00:00:00
abstract::An overview of the possible factors that might contribute to the development of cerebral vasospasm is presented, with particular emphasis on the possibility that spasm arises from a malfunction of the regulatory or contractile processes in smooth muscle cells. This possibility is emphasized because the evidence for ce...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.16.4.573
更新日期:1985-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The Montreal Cognitive Assessment (MoCA) and Addenbrooke's Cognitive Examination-Revised (ACE-R) are proposed as short cognitive tests for use after stroke, but there are few published validations against a neuropsychological battery. We studied the relationship between MoCA, ACE-R, Mini-Mental S...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.633586
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Arterial stiffness is associated with an increased risk of myocardial infarction and stroke, independent of classical vascular risk factors. Vascular factors and stroke are associated with cognitive function and dementia. We examined whether arterial stiffness was independently associated with co...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000257998.33768.87
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several markers of poststroke cognitive impairment have been reported. The role of brain cortical volume remains uncertain. The aim of this study was to evaluate the influence of brain cortical volume on cognitive outcomes using a voxel-based morphometry approach in subjects without prestroke dem...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017646
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several prognostic scores have been developed to predict the risk of symptomatic intracranial hemorrhage (sICH) after ischemic stroke thrombolysis. We compared the performance of these scores in a multicenter cohort. METHODS:We merged prospectively collected data of patients with consecutive isc...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.113.003806
更新日期:2014-03-01 00:00:00
abstract::We investigated the prevalence of carotid atherosclerosis, including mild early lesions, and its association with cervical bruits and various risk factors (age, male sex, hypertension, hyperlipidemia, diabetes mellitus, obesity, and cigarette smoking) in 232 consecutive Japanese patients. High-resolution real-time B-m...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.11.1567
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stent placement has been applied in small case series as a rescue therapy in combination with different thrombolytic agents, percutaneous balloon angioplasty (PTA), and mechanical thromboembolectomy (MT) in acute stroke treatment. These studies report a considerable mortality and a high rate of i...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.108.533810
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:A pulsatility index (PI) represents vascular resistance distal to an examined artery. The purpose of the present study was to evaluate an association between plasma total homocysteine (tHcy) and PIs of the cerebral arteries in patients with ischemic stroke. METHODS:Consecutive patients with isch...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.558403
更新日期:2009-10-01 00:00:00