Ultrasonic evaluation of early carotid atherosclerosis.

abstract：BACKGROUND AND PURPOSE:Although both general and abdominal adiposity are well-established risk factors for coronary heart disease, their associations with stroke are less well characterized, particularly in generally lean Asian populations. METHODS:We evaluated associations of body mass index (BMI), waist-hip ratio (W...

journal_title：Stroke

authors： Zhang X,Shu XO,Gao YT,Yang G,Li H,Zheng W

更新日期：2009-04-01 00:00:00

abstract：:The reactivity of cerebral blood vessels to changes in PaCO2 in areas of the cerebral cortex with or without diaschisis was investigated in 13 patients in a subacute or chronic stage after a small capsular infarct. A focal area of hypoperfusion (area of diaschisis) was detected in the ipsilateral sensorimotor cortex i...

journal_title：Stroke

authors： Takano T,Nagatsuka K,Ohnishi Y,Takamitsu Y,Matsuo H,Matsumoto M,Kimura K,Kamada T

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vascular effects of mental stress are only partially understood. Therefore, we studied effects of chronic stress and heart rate (HR) on endothelial function and cerebral ischemia. METHODS:129S6/SvEv mice were randomized to the I(f)-channel inhibitor ivabradine (10 mg/kg per day) or vehicle and u...

journal_title：Stroke

authors： Custodis F,Gertz K,Balkaya M,Prinz V,Mathar I,Stamm C,Kronenberg G,Kazakov A,Freichel M,Böhm M,Endres M,Laufs U

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebrovascular disease can complicate head and neck radiotherapy and result in transient ischemic attack and ischemic stroke. Although the incidence of radiation vasculopathy is predicted to rise with improvements in median cancer survival, the pathogenesis, natural history, and management of th...

journal_title：Stroke

authors： Plummer C,Henderson RD,O'Sullivan JD,Read SJ

更新日期：2011-09-01 00:00:00

abstract：:We produced unilateral photochemical infarcts in the hindlimb sensorimotor neocortex of 186 rats by intravenous injection of the fluorescein derivative rose bengal and focal illumination of the intact skull surface. Infarcted rats showed specific, long-lasting deficits in tactile and proprioceptive placing reactions o...

journal_title：Stroke

authors： De Ryck M,Van Reempts J,Borgers M,Wauquier A,Janssen PA

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The National Institutes of Health Stroke Scale (NIHSS) is a valid, reproducible scale that measures neurological deficit. Of 42 possible points, 7 points are directly related to measurement of language compared with only 2 points related to neglect. METHODS:We examined the placebo arm of the NIN...

journal_title：Stroke

authors： Woo D,Broderick JP,Kothari RU,Lu M,Brott T,Lyden PD,Marler JR,Grotta JC

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mild hypothermia is possibly the single most effective method of cerebroprotection developed to date. However, many questions regarding mild hypothermia remain to be addressed before its potential implementation in the treatment of human stroke. Here we report the results of 2 studies designed to...

journal_title：Stroke

authors： Maier CM,Ahern Kv,Cheng ML,Lee JE,Yenari MA,Steinberg GK

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The lipid peroxidation inhibitor U-101033E was examined for effects on cerebral blood flow (CBF), cortical tissue hemoglobin oxygen saturation (HbSo2), and neuronal damage. METHODS:Fifteen minutes of global cerebral ischemia was induced by two-vessel occlusion and hypobaric hypotension. Wistar r...

journal_title：Stroke

authors： Soehle M,Heimann A,Kempski O

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies of peripheral arteries in hypercholesterolemic animals suggest that increased generation of superoxide contributes to endothelial dysfunction, especially in the presence of atherosclerotic lesions. We tested the hypothesis that vasomotor function is impaired in cerebral arterioles during ...

journal_title：Stroke

authors： Kitayama J,Faraci FM,Lentz SR,Heistad DD

更新日期：2007-07-01 00:00:00

abstract：:The presence of hyperglycemia prior to stroke or cardiac arrest can increase neuronal damage caused by brain ischemia. Acute hyperglycemia shows this effect in animal models of stroke. However, chronic hyperglycemia and chronic hyperglycemia with additional acute elevation of blood glucose are more common premorbid st...

journal_title：Stroke

authors： Duckrow RB,Beard DC,Brennan RW

更新日期：1987-01-01 00:00:00

abstract：:As part of a prospective study of mood disorders in stroke patients, interviews were obtained from 37 patients at 1 year and 48 patients at 2 years follow-up. In-hospital evaluations for these 65 follow-up patients found that 9 patients (14%) had symptom clusters of major depression, 12 patients (18%) had symptom clus...

journal_title：Stroke

authors： Robinson RG,Bolduc PL,Price TR

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have previously reported that extracellular ATP activates P(2u) receptors and increases intracellular free Ca(2+) ([Ca(2+)](i)) by G protein/phospholipase C/inositol 1,4,5-triphosphate pathways in cerebral artery smooth muscle cells. However, the possible contribution of other signaling pathwa...

journal_title：Stroke

authors： Aoki K,Zubkov AY,Parent AD,Zhang JH

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The goal of this study was to determine whether release of endothelium-derived relaxing factor (EDRF) from carotid artery in response to acetylcholine is altered by aging. METHODS:Responses were examined in arteries from Wistar rats 6 to 8 months old (young rats), 24 to 26 months old (old rats),...

journal_title：Stroke

authors： Paternò R,Faraci FM,Heistad DD

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few studies are available that have addressed the prevalence of early-onset dementia (EOD), including early-onset Alzheimer disease and other forms of dementia in Japan. METHODS:A 2-step postal survey was sent to all of the 2475 institutions providing medical or care services for individuals wit...

journal_title：Stroke

authors： Ikejima C,Yasuno F,Mizukami K,Sasaki M,Tanimukai S,Asada T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our investigation sought to determine whether neonatal brain ischemic vascular and metabolic effects were altered by repeated episodes of ischemia. METHODS:We studied twelve piglets using in vivo magnetic resonance spectroscopy to obtain multiple, simultaneous measurements of cerebral blood flow...

journal_title：Stroke

authors： Laptook AR,Corbett RJ,Ruley J,Olivares E

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to investigate the periprocedural morbidity, mortality, and long-term clinical and angiographic follow-up using stent-assisted coiling and stenting alone for treatment of cranial fusiform dissecting and atherosclerotic aneurysms. METHODS:The Institutional Review Boa...

journal_title：Stroke

authors： Wakhloo AK,Mandell J,Gounis MJ,Brooks C,Linfante I,Winer J,Weaver JP

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This work was undertaken to determine to what degree long-term neurofunctional outcome of neonatal hypoxic-ischemic (HI) brain injury in mice correlates with anatomical extent of cerebral damage assessed by magnetic resonance imaging (MRI) and histopathology. METHODS:On postnatal day 7, mice wer...

journal_title：Stroke

authors： Ten VS,Wu EX,Tang H,Bradley-Moore M,Fedarau MV,Ratner VI,Stark RI,Gingrich JA,Pinsky DJ

更新日期：2004-09-01 00:00:00

abstract：:The Stenting and Aggressive Medical Management for Preventing Recurrent Stroke and Intracranial Stenosis (SAMMPRIS) trial, a randomized clinical trial comparing aggressive medical management to stenting with aggressive medical management for symptomatic intracranial stenosis, was prematurely halted when a high rate of...

journal_title：Stroke

authors： Marks MP

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We assessed the influence of different visual stimuli and the reproducibility and habituation of evoked flow responses using simultaneous two-channel transcranial Doppler monitoring and flow velocity averaging. METHODS:We measured stimulus-related percentage changes in posterior cerebral, basila...

journal_title：Stroke

authors： Sturzenegger M,Newell DW,Aaslid R

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Insular injuries are known to cause autonomic derangements. Patients with ruptured middle cerebral artery aneurysms frequently develop temporal hematomas (THs) in addition to subarachnoid hemorrhages, and those with TH may sustain autonomic derangements more frequently than those without TH. Hemi...

journal_title：Stroke

authors： Inamasu J,Sugimoto K,Watanabe E,Kato Y,Hirose Y

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to describe the frequency and characteristics of acute ischemic stroke and transient ischemic attacks presenting predominantly with amnesia (ischemic amnesia) and to identify clinical clues for differentiating them from transient global amnesia (TGA). METHODS:We retrospectively analyzed...

journal_title：Stroke

authors： Michel P,Beaud V,Eskandari A,Maeder P,Demonet JF,Eskioglou E

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fibrinogen is an independent risk factor for coronary events in population-based studies and in patients with coronary heart disease, but there is uncertainty about prediction of stroke, particularly in secondary prevention. METHODS:We studied unpublished data from 3 prospective studies of patie...

journal_title：Stroke

authors： Rothwell PM,Howard SC,Power DA,Gutnikov SA,Algra A,van Gijn J,Clark TG,Murphy MF,Warlow CP

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Post hoc analyses of randomized controlled clinical trials evaluating mechanical thrombectomy have suggested that admission-to-groin-puncture (ATG) delays are associated with reduced reperfusion rates. Purpose of this analysis was to validate this association in a real-world cohort and to find as...

journal_title：Stroke

authors： Kaesmacher J,Maamari B,Meinel TR,Piechowiak EI,Mosimann PJ,Mordasini P,Goeldlin M,Arnold M,Dobrocky T,Boeckh-Behrens T,Berndt M,Michel P,Requena M,Benali A,Pierot L,Mendes Pereira V,Boulouis G,Brehm A,Sporns PB,Ospe

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Space-occupying brain edema is a life-threatening complication in patients with large middle cerebral artery (MCA) infarction. To determine predictors of this detrimental process, we investigated alterations of extracellular non-transmitter amino acid concentrations in peri-infarct tissue. METHO...

journal_title：Stroke

authors： Bosche B,Dohmen C,Graf R,Neveling M,Staub F,Kracht L,Sobesky J,Lehnhardt FG,Heiss WD

更新日期：2003-12-01 00:00:00

abstract：:Choline concentration is rate limiting in the synthesis of acetylcholine. There is a negative arteriovenous difference for choline concentration across the brain, indicating the steady output of choline from this organ. Cerebral ischemia may increase extracellular choline concentration by interfering with its removal ...

journal_title：Stroke

authors： Scremin OU,Jenden DJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:[123I]Iomazenil is a specific radioligand for the central benzodiazepine receptor that may be useful as an indicator of the intactness of cortical neurons after focal cerebral ischemia. We evaluated the binding of this receptor in reperfused cortex among patients with ischemic stroke to detect vi...

journal_title：Stroke

authors： Nakagawara J,Sperling B,Lassen NA

更新日期：1997-01-01 00:00:00

abstract：:Background and Purpose- In this era of endovascular therapy (EVT) with early, complete recanalization and reperfusion, we have observed an even more rapid apparent diffusion coefficient (ADC) normalization within the acute ischemic lesion compared with the natural history or IV-tPA-treated patient. In this study, we a...

journal_title：Stroke

authors： Hsia AW,Luby M,Cullison K,Burton S,Armonda R,Liu AH,Leigh R,Nadareishvili Z,Benson RT,Lynch JK,Latour LL

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In 6% to 9% of patients with subarachnoid hemorrhage (SAH), familial aggregation occurs; truly familial cases carry a worse prognosis than sporadic cases and raise the question of screening. If relatives have died from SAH, the family history is often the only available clue to the diagnosis, but...

journal_title：Stroke

authors： Bromberg JE,Rinkel GJ,Algra A,Greebe P,Beldman T,van Gijn J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolytic treatment of stroke carries the risk of hemorrhagic transformation. Therefore, the potential of MRI for prediction of recombinant tissue plasminogen activator (rtPA)-induced bleeding is explored to identify patients in whom rtPA treatment may provoke such complications. METHODS:Spon...

journal_title：Stroke

authors： Neumann-Haefelin C,Brinker G,Uhlenküken U,Pillekamp F,Hossmann KA,Hoehn M

更新日期：2002-05-01 00:00:00

abstract：:Spontaneous dissections of the extracranial internal carotid artery are diagnosed more frequently as their clinical and angiographic features are more widely recognized. Familial occurrence of spontaneous dissection of the internal carotid artery has not been previously reported. We describe the occurrence of this ent...

journal_title：Stroke

authors： Mokri B,Piepgras DG,Wiebers DO,Houser OW

更新日期：1987-01-01 00:00:00