Cost-effectiveness of intravenous thrombolysis with alteplase within a 3-hour window after acute ischemic stroke.

abstract：BACKGROUND AND PURPOSE:The bedside clinical assessment of the patient with suspected stroke has not been well studied. Improving clinical skills may accelerate patient progress through the emergency department. We aimed to determine the frequency and nature of stroke mimics and to identify the key clinical features tha...

journal_title：Stroke

authors： Hand PJ,Kwan J,Lindley RI,Dennis MS,Wardlaw JM

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previously published meta-analyses exploring the effect of statins on stroke incidence included 20,000 patients and found a 2% to 30% risk reduction. It is not clear whether this is attributable to low-density lipoprotein-cholesterol (LDL-C) reduction. Statin trials have now included >90,000 pati...

journal_title：Stroke

authors： Amarenco P,Labreuche J,Lavallée P,Touboul PJ

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess the long-term predictive usefulness of bone mineral density (BMD) for stroke incidence and stroke mortality. METHODS:The First National Health and Nutrition Examination Survey data were obtained from a nationally representative sample of noninstitutionalized civilians. A coho...

journal_title：Stroke

authors： Mussolino ME,Madans JH,Gillum RF

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hypothermia reduces neuronal damage in animal stroke models. Whether hypothermia is neuroprotective in patients with acute stroke remains to be clarified. In this case-control study, we evaluated the feasibility and safety of inducing modest hypothermia by a surface cooling method in awake patien...

journal_title：Stroke

authors： Kammersgaard LP,Rasmussen BH,Jørgensen HS,Reith J,Weber U,Olsen TS

更新日期：2000-09-01 00:00:00

abstract：:This study, in biologically bred hyperglycemic diabetic rats, examined the effect of a intravenous insulin infusion (1.5 units.hr-1) on blood, plasma, and brain glucose concentrations to determine their relationship during decreasing blood and plasma glucose levels. The data were compared to saline-treated diabetic ra...

journal_title：Stroke

authors： Hofer RE,Lanier WL

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To assess the association of lesion location and risk of aspiration and to establish predictors of transient versus extended risk of aspiration after supratentorial ischemic stroke. METHODS:Atlas-based localization analysis was performed in consecutive patients with MRI-proven first-time acute s...

journal_title：Stroke

authors： Galovic M,Leisi N,Müller M,Weber J,Abela E,Kägi G,Weder B

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of acute ischemic stroke (AIS) cause is crucial for guidance of secondary prevention. Previous studies have yielded inconsistent results regarding possible correlations between AIS cause and thrombus composition, as assessed by semiquantitative histological analysis. Here, we perfo...

journal_title：Stroke

authors： Di Meglio L,Desilles JP,Solonomenjanahary M,Labreuche J,Ollivier V,Dupont S,Deschildre C,Maacha MB,Consoli A,Lapergue B,Piotin M,Blanc R,Ho-Tin-Noe B,Mazighi M,compoCLOT study group†.

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial direct current stimulation is emerging as a promising tool for the treatment of several neurological conditions, including cerebral ischemia. The therapeutic role of this noninvasive treatment is, however, limited to chronic phases of stroke. We thus ought to investigate whether diff...

journal_title：Stroke

authors： Peruzzotti-Jametti L,Cambiaghi M,Bacigaluppi M,Gallizioli M,Gaude E,Mari S,Sandrone S,Cursi M,Teneud L,Comi G,Musco G,Martino G,Leocani L

更新日期：2013-11-01 00:00:00

abstract：:We devised the present experiments to assess the effects of ischemia on the production of dopamine in the caudate nucleus of spontaneously hypertensive stroke-resistant rats. Ringer's solution was continuously perfused at a rate of 10 microliters/min through 0.2-mm-diameter dialysis tubing implanted in the rat's cauda...

journal_title：Stroke

authors： Kawano T,Tsutsumi K,Miyake H,Mori K

更新日期：1988-12-01 00:00:00

abstract：:Diphenyl-para-phenylenediamine (DPPD) is an antioxidant that has been shown to decrease liver damage due to the peroxidative process of carbon tetrachloride in rats and to ameliorate cold-induced cerebral edema in cats. Because lipid peroxidation disrupts the integrity of the plasma membrane, a process believed to occ...

journal_title：Stroke

authors： Butterfield JD,McGraw CP

更新日期：1978-09-01 00:00:00

abstract：:Background and Purpose- Diffusion-weighted imaging (DWI) hyperintensities in intracerebral hemorrhage (ICH) are associated with increased risk of recurrent ICH, cognitive impairment, and death, but whether these lesions are specific to a subtype of ICH remains uncertain. We investigated the association between DWI les...

journal_title：Stroke

authors： Boulanger M,Schneckenburger R,Join-Lambert C,Werring DJ,Wilson D,Hodel J,Zuber M,Touzé E

更新日期：2018-12-07 00:00:00

abstract：:We investigated the temporal threshold for focal cerebral infarction in the spontaneously hypertensive rat. The right middle cerebral artery and common carotid artery were occluded for 0, 1, 2, 3, 4, or 24 hours, and all the animals were sacrificed 24 hours after the onset of ischemia. Cortical infarct volumes and ede...

journal_title：Stroke

authors： Kaplan B,Brint S,Tanabe J,Jacewicz M,Wang XJ,Pulsinelli W

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:An increase in intima-media thickness (IMT) in the common carotid artery (CCA) is commonly used as a marker of atherosclerosis. The purpose of this study was to investigate the relationship between IMT in the CCA and atherosclerosis in the carotid bifurcation. METHODS:182 consecutive patients (m...

journal_title：Stroke

authors： Rosfors S,Hallerstam S,Jensen-Urstad K,Zetterling M,Carlström C

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to investigate the associations of dietary and total potassium, magnesium, and calcium intakes with stroke occurrence. METHODS:A prospective cohort study was conducted among 36 094 participants aged 21 to 70 years. Dietary intake was assessed with a food frequency questionnaire. RESULT...

journal_title：Stroke

authors： Sluijs I,Czernichow S,Beulens JW,Boer JM,van der Schouw YT,Verschuren WM,Grobbee DE

更新日期：2014-04-01 00:00:00

abstract：:Cerebral cortical blood flow was measured in rabbits with the hydrogen clearance technique. The reactivity to CO2, tested by changing the end tidal CO2 (ETCO2) in steps from 2 to 6 volumes %, was highly dependent on the kind of anesthesia, being greatest under halothane and least under nitrous oxide. Reactivity to CO2...

journal_title：Stroke

authors： Scremin OU,Rubinstein EH,Sonnenschein RR

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A previous trial (the Clomethiazole Acute Stroke Study) generated the hypothesis that clomethiazole is effective in patients with a major ischemic stroke (total anterior circulation syndrome), and this was tested in the present study. METHODS:A total of 1198 patients with major ischemic stroke a...

journal_title：Stroke

authors： Lyden P,Shuaib A,Ng K,Levin K,Atkinson RP,Rajput A,Wechsler L,Ashwood T,Claesson L,Odergren T,Salazar-Grueso E,CLASS-I\/H\/T Investigators.

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A prominent feature of cerebral ischemia is the excessive intracellular accumulation of both Na(+) and Ca(2+) ions, which results in subsequent cell death. The plasma membrane Na(+)/Ca(2+) exchanger (NCX), regulates the distribution of these ions acting either in the forward mode or in its revers...

journal_title：Stroke

authors： Tortiglione A,Picconi B,Barone I,Centonze D,Rossi S,Costa C,Di Filippo M,Tozzi A,Tantucci M,Bernardi G,Annunziato L,Calabresi P

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Stroke patients are heterogeneous not only with respect to etiology but also in terms of preexisting clinical conditions. Approximately one fifth of patients with acute stroke are hyperglycemic and/or have had a recent infectious or inflammatory condition. Summary of Review-- Experimental research indicates ...

journal_title：Stroke

authors： Kent TA,Soukup VM,Fabian RH

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increased mean platelet volume (MPV), indicating higher platelet reactivity, is associated with an increased risk of myocardial infarction. Higher levels of MPV have been found in patients with acute ischemic stroke than in control subjects. Data from smaller studies regarding an association betw...

journal_title：Stroke

authors： Greisenegger S,Endler G,Hsieh K,Tentschert S,Mannhalter C,Lalouschek W

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is scant population-based information on incidence and risk factors for ischemic stroke subtypes. METHODS:We identified all 454 residents of Rochester, Minn, with a first ischemic stroke between 1985 and 1989 from the Rochester Epidemiology Project medical records linkage system. We used S...

journal_title：Stroke

authors： Petty GW,Brown RD Jr,Whisnant JP,Sicks JD,O'Fallon WM,Wiebers DO

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To assess the role of the endothelial nitric oxide synthase (eNOS) gene variants as risk factors for early atherosclerosis, we sought to investigate whether two polymorphisms located in the exon 7 (Glu298-->Asp) and in the promoter region (T-786-->C) of the eNOS gene were associated with function...

journal_title：Stroke

authors： Paradossi U,Ciofini E,Clerico A,Botto N,Biagini A,Colombo MG

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke MRI protocols provide useful information about underlying vessel pathologies in the anterior circulation by means of intracranial time-of-flight angiography. However, these protocols mostly fail in the posterior circulation to differentiate between congenital variants and secondary thrombo...

journal_title：Stroke

authors： Freund W,Kassubek J,Aschoff AJ,Huber R

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although chemokines have been implicated in cardiovascular diseases, few studies have addressed the role of these inflammatory mediators in ischemic stroke. This study tested the hypothesis that RANTES (CCL5; regulated on activation, normal T-cell expressed and secreted) mediates the cerebral mic...

journal_title：Stroke

authors： Terao S,Yilmaz G,Stokes KY,Russell J,Ishikawa M,Kawase T,Granger DN

更新日期：2008-09-01 00:00:00

abstract：:Twenty-four cats had an intravenous infusion of either Fluosol or saline and then were subjected to 2 hours of middle cerebral artery occlusion. All the animals infused with Fluosol and one-half the animals infused with saline were ventilated with 100% O2. Tissue oxygen availability and regional cerebral blood flow we...

journal_title：Stroke

authors： Kolluri S,Heros RC,Hedley-Whyte ET,Vonsattel JP,Miller D,Zervas NT

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Disabling anxiety affects a quarter of stroke survivors but access to treatment is poor. We developed a telemedicine model for delivering guided self-help cognitive behavioral therapy (CBT) for anxiety after stroke (TASK-CBT). We aimed to evaluate the feasibility of TASK-CBT in a randomized contr...

journal_title：Stroke

authors： Chun HY,Carson AJ,Tsanas A,Dennis MS,Mead GE,Calabria C,Whiteley WN

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patient selection is crucial in the endovascular treatment of acute ischemic stroke patients. Baseline computed tomographic (CT) images, evaluated with the Alberta Stroke Program Early CT Scale (ASPECTS), are considered significant predictors of outcome. In this study, we evaluated CT images and ...

journal_title：Stroke

authors： Psychogios MN,Schramm P,Frölich AM,Kallenberg K,Wasser K,Reinhardt L,Kreusch AS,Jung K,Knauth M

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few studies are available that have addressed the prevalence of early-onset dementia (EOD), including early-onset Alzheimer disease and other forms of dementia in Japan. METHODS:A 2-step postal survey was sent to all of the 2475 institutions providing medical or care services for individuals wit...

journal_title：Stroke

authors： Ikejima C,Yasuno F,Mizukami K,Sasaki M,Tanimukai S,Asada T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We earlier reported that risk factors for stroke prepare brain stem tissue for a modified Shwartzman reaction, including the development of ischemia and hemorrhage and the production of tumor necrosis factor-alpha, after a provocative dose of lipopolysaccharide. In the present study, we sought to...

journal_title：Stroke

authors： Sirén AL,Liu Y,Feuerstein G,Hallenbeck JM

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated low density lipoprotein and reduced high density lipoprotein cholesterol may increase the risk of atherothrombotic brain infarction, but the metabolic mechanisms accounting for this relation are poorly understood. METHODS:The kinetic parameters of low density and high density lipoprotei...

journal_title：Stroke

authors： Alam R,Yatsu FM,Kasturi R,Bui G

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increased cortical microvascularization has been proposed to be a Moyamoya disease (MMD)-specific characteristic. It was the aim of our study to characterize the anatomic pattern and microhemodynamics of cortical microvascularization in MMD. METHODS:Intraoperative indocyanine green videoangiogra...

journal_title：Stroke

authors： Czabanka M,Peña-Tapia P,Schubert GA,Woitzik J,Vajkoczy P,Schmiedek P

更新日期：2008-06-01 00:00:00