Abstract:
:Background and Purpose- Diffusion-weighted imaging (DWI) hyperintensities in intracerebral hemorrhage (ICH) are associated with increased risk of recurrent ICH, cognitive impairment, and death, but whether these lesions are specific to a subtype of ICH remains uncertain. We investigated the association between DWI lesions and ICH subtype and explored the risk factors for DWI lesions. Methods- In a systematic review of ICH studies, we identified those reporting prevalence of DWI lesions. Two reviewers independently assessed study eligibility and risk of bias and collected data. We determined the pooled prevalence of DWI lesions within 90 days after ICH onset for cerebral amyloid angiopathy- and hypertensive angiopathy-related ICH using random-effects meta-analysis. We calculated odds ratios to compare prevalence of DWI lesions by ICH subtype and to assess risk factors for DWI lesions. Results- Eleven studies (1910 patients) were included. The pooled prevalence of DWI lesions was 18.9% (95% CI, 11.1-26.7) in cerebral amyloid angiopathy- and 21.0% (95% CI, 15.3-26.6) in hypertensive angiopathy-related ICH. There was no difference in the prevalence of DWI lesions between cerebral amyloid angiopathy- (64/292 [21.9%]) and hypertensive angiopathy-related ICH (79/370 [21.4%]; odds ratio, 1.25; 95% CI, 0.73-2.15) in the 5 studies reporting data on both ICH pathogeneses. In all ICH, presence of DWI lesions was associated with neuroimaging features of microangiopathy (leukoaraiosis extension, previous ICH, and presence, and number of microbleeds) but not with vascular risk factors or the use of antithrombotic therapies. Conclusions- Prevalence of DWI lesions in acute ICH averages 20%, with no difference between cerebral amyloid angiopathy- and hypertensive angiopathy-related ICH. Detection of DWI lesions may add valuable information to assess the progression of the underlying microangiopathy.
journal_name
Strokejournal_title
Strokeauthors
Boulanger M,Schneckenburger R,Join-Lambert C,Werring DJ,Wilson D,Hodel J,Zuber M,Touzé Edoi
10.1161/STROKEAHA.118.021407subject
Has Abstractpub_date
2018-12-07 00:00:00pages
STROKEAHA118021407eissn
0039-2499issn
1524-4628pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Unstable atherosclerotic plaques are characterized by increased macrophages and reduced smooth muscle cells (SMCs) and collagen content. Endoglin, an accessory transforming growth factor-beta (TGFbeta) receptor, is a modulator of TGFbeta signaling recently found to be expressed on SMCs in atheros...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.108.522284
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Estrogen receptor alpha (ESR1) gene variation is associated with a range of important estrogen-dependent characteristics, including responses of lipid profile and atherosclerotic severity to hormone replacement therapy, coronary heart disease risk, and migraine. The roles that reproductive steroi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000181088.76518.ec
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Because the blood circulation system of retina and brain are closely related to each other, we examined whether stroke is associated with localized retinal nerve fiber layer defects (RNFLDs). METHODS:Patients with acute ischemic stroke as part of a hospital-based study group were compared with t...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.113.004629
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Declining trends in the incidence and mortality of stroke have been observed in Finland since the beginning of the 1980s until 1997. In this study we analyzed the trends in fatal and nonfatal strokes in Finland during 1991-2002. METHODS:The Finnish Hospital Discharge Register was linked to the N...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000152945.28543.4a
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several observations indicate that, during energy deprivation, endogenous dopamine may become neurotoxic. Accordingly, the nucleus striatum is a preferential site of silent infarcts in humans, and experimental ischemia caused by homolateral carotid occlusion selectively damages this dopamine-enri...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.0000038093.42512.0f
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Our objective was to study age-specific prevalence, computed tomographic (CT) characteristics, risk factors, and the prognostic influence on stroke outcome of silent infarction in acute stroke patients. METHODS:The study was prospective and community-based and included 801 acute stroke patients,...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.1.97
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Adequate control of blood pressure (BP) is a cornerstone in stroke prevention. This study explored the risk of stroke in relation to the quality of BP control in a population-based cohort and whether control of hypertension was related to background characteristics of patients. METHODS:A total o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000158925.12740.87
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Noncontrast computed tomographic (CT) hypodensities have been shown to be associated with hematoma expansion in intracerebral hemorrhage (ICH), but their impact on functional outcome is yet to be determined. We evaluated whether baseline noncontrast CT hypodensities are associated with poor clini...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.014425
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Epidemiological and laboratory studies suggest that increasing concentrations of plasma homocysteine (total homocysteine [tHcy]) accelerate cardiovascular disease by promoting vascular inflammation, endothelial dysfunction, and hypercoagulability. METHODS:We conducted a randomized controlled tri...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.STR.0000150494.91762.70
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intravenous tissue plasminogen activator (tPA) is an economically worthwhile but underused treatment option for acute ischemic stroke. We sought to identify the extent of tPA use in Canadian medical centers and the potential savings associated with increased use nationally and by province. METHO...
journal_title:Stroke
pub_type: 信件
doi:10.1161/STROKEAHA.106.479477
更新日期:2007-06-01 00:00:00
abstract::Background and Purpose- Carotid web (CW) is a rare form of focal fibromuscular dysplasia defined as an abnormal shelf-like projection of intimal fibrous tissue into the carotid bulb. It is theorized that CW leads to ischemic stroke secondary to blood flow stasis and subsequent embolization. The natural history and opt...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.021907
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Because the diagnosis and treatment of carotid artery disease may reduce the rate of stroke, the aim of this study was to determine whether a diet intervention was associated with incident carotid artery disease. METHODS:Participants were 48 835 postmenopausal women aged 50 to 79 years who were ...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/STROKEAHA.114.005096
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Disabling anxiety affects a quarter of stroke survivors but access to treatment is poor. We developed a telemedicine model for delivering guided self-help cognitive behavioral therapy (CBT) for anxiety after stroke (TASK-CBT). We aimed to evaluate the feasibility of TASK-CBT in a randomized contr...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.120.029042
更新日期:2020-08-01 00:00:00
abstract::Background and Purpose- Cerebral small vessel disease (SVD) is associated with increased stroke risk and poor stroke outcomes. We aimed to evaluate whether chronic SVD burden is associated with poor recruitment of collaterals in large-vessel occlusive stroke. Methods- Consecutive patients with middle cerebral artery o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.027661
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The National Institutes of Health Stroke Scale (NIHSS) is a valid, reproducible scale that measures neurological deficit. Of 42 possible points, 7 points are directly related to measurement of language compared with only 2 points related to neglect. METHODS:We examined the placebo arm of the NIN...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.11.2355
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Ageing is associated with a decline in cerebral blood flow. Animal studies have shown that cholesterol-lowering therapy with statins might preserve cerebral blood flow (CBF). We examined the effect of 40 mg pravastatin on the decline in CBF and brain volume in a subset of elderly subjects partici...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.STR.0000173162.88600.29
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Disturbed cerebral autoregulation has been reported to correlate with an unfavorable outcome after head injury. Using transcranial Doppler ultrasonography, we investigated whether hemodynamic responses to spontaneous variations of cerebral perfusion pressure (CPP) provide reliable information on ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.10.1829
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Elevated leukocyte count has been associated with cardiovascular and cerebrovascular disease in several epidemiological studies. We sought to determine whether white blood cell count (WBC) is associated with carotid plaque thickness in a stroke-free, multiethnic cohort. METHODS:For this cross-se...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.32.4.842
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Dysregulation of vessel wall formation, growth, and maintenance may confer susceptibility of stroke. METHODS:We tested the hypothesis that variants in 2 genes encoding vascular endothelial growth factor and vascular endothelial growth factor receptor-2 are associated with susceptibility to strok...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.109.554394
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Transtemporal insonation in transcranial Doppler sonography is often impaired by an insufficient signal-to-noise ratio, especially in elderly patients. A transpulmonary stable air microbubble suspension was injected intravenously in humans as an intracranial ultrasonic contrast agent. METHODS:In...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.24.12.1903
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Because thromboembolic events are frequently observed in primary antiphospholipid syndrome (PAPS), we assessed the risk factors for new thrombotic episodes. METHODS:Fifty-six PAPS patients (mean age, 37+/-10 years) were prospectively studied for 5 years. The preliminary Sapporo classification cr...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000170645.40562.09
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Unaccustomed strenuous physical exertion can trigger myocardial infarction, but little is known about the mechanisms precipitating subarachnoid hemorrhage (SAH). METHODS:We identified all cases of first-ever SAH among the combined populations (2.8 million) of 4 urban centers in Australia and New...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000077015.90334.A7
更新日期:2003-07-01 00:00:00
abstract::Using in vivo brain microdialysis, we studied amino acid release in the striatum and cortex of eight rats following permanent middle cerebral artery occlusion. We then processed all brains for histopathologic assessment of the volume of ischemic damage 4 hours after occlusion. Ischemic damage was varied by occlusion o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.12.1727
更新日期:1990-12-01 00:00:00
abstract::Acute thromboembolic occlusion of the basilar artery accounts for 6% to 10% of large-vessel stroke in humans. Because of the brain region supplied by this artery, the case fatality rate is the highest for all ischemic stroke subtypes, ranging from 40% to 86%. Patients who undergo successful recanalization of the basil...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.STR.0000247897.33267.42
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Using the dexamethasone suppression test, we studied the suppressibility of the cortisol axis and its clinical determinants at various time points after stroke. A major aim was to examine the dexamethasone test as a diagnostic tool for the diagnosis of major depression in stroke patients. METHOD...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.24.1.52
更新日期:1993-01-01 00:00:00
abstract::Twenty-four cats had an intravenous infusion of either Fluosol or saline and then were subjected to 2 hours of middle cerebral artery occlusion. All the animals infused with Fluosol and one-half the animals infused with saline were ventilated with 100% O2. Tissue oxygen availability and regional cerebral blood flow we...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.5.976
更新日期:1986-09-01 00:00:00
abstract::Contrast-enhanced computed tomography of the neck permits low-risk evaluation of morphologic complications of carotid plaque, including (and foremost) calcification. To investigate the patterns and clinical significance of calcified deposits in the cervical carotid arteries using computed tomography we studied 40 pati...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.11.1472
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary arteriopathy, which mainly involves the brain causing stroke and dementia. Mice expressing the mutated protein display early dysfunction in vasoreactivity in resistance arteries, b...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.490029
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Physical and psychological characteristics in adolescence are associated with subsequent stroke risk. Our aim is to investigate their relevance to length of hospital stay and risk of second stroke. METHODS:Swedish men born between 1952 and 1956 (n=237 879) were followed from 1987 to 2010 using i...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.014265
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Efficacy of intravenous thrombolysis in acute ischemic stroke declines with increasing time to treatment initiation. Previous small-scale studies suggested that the earlier patients arrive, the longer it takes to administer recombinant tissue plasminogen activator. METHODS:Of 32 529 patients wit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.590372
更新日期:2010-09-01 00:00:00