Binding of the hypoxia tracer [3H]misonidazole in cerebral ischemia.

abstract：BACKGROUND AND PURPOSE:The aim of our study was to clarify the pathophysiology of perioperative cerebral complications during carotid endarterectomy in our series. METHODS:By means of transcranial Doppler ultrasonography and stump pressure measurement, we monitored 112 patients who underwent carotid endarterectomy und...

journal_title：Stroke

authors： Finocchi C,Gandolfo C,Carissimi T,Del Sette M,Bertoglio C

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis (IVT) within 4.5 hours from symptom onset improves functional outcome in patients with acute ischemic stroke. Its use in patients with previous stroke within the preceding 3 months is contraindicated because of the assumed higher risk of intracranial hemorrhage. In additi...

journal_title：Stroke

authors： Kahles T,Mono ML,Heldner MR,Baumgartner RW,Sarikaya H,Luft A,Bohlhalter S,Traenka C,Engelter ST,Kurka N,Köhrmann M,Curtze S,Michel P,Tatlisumak T,Nedeltchev K

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We designed a prospective sequential pretreatment and posttreatment MRI study to assess the relation between neuroimaging parameters and clinical outcome in patients treated with intravenous recombinant tissue-type plasminogen activator (rtPA). METHODS:Patients with symptoms of acute hemispheric...

journal_title：Stroke

authors： Nighoghossian N,Hermier M,Adeleine P,Derex L,Dugor JF,Philippeau F,Ylmaz H,Honnorat J,Dardel P,Berthezène Y,Froment JC,Trouillas P

更新日期：2003-02-01 00:00:00

abstract：:We have evaluated carotid gamma imaging using 111Indium-labelled platelets in the diagnosis of carotid artery disease and measured the accumulation of labelled platelets on endarterectomy specimens. Autologous 111In labelled platelets were injected in 25 patients with TIA. Gamma images were then taken daily and indepe...

journal_title：Stroke

authors： Goldman M,Leung JO,Aukland A,Hawker RJ,Drolc Z,McCollum CN

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In malignant cerebral venous thrombosis (CVT) patients, emergency decompressive surgery has been suggested as a life-saving procedure. We report 12 patients with malignant CVT, among whom 8 underwent operation. METHODS:Retrospective study of 12 patients from 3 stroke units who had a malignant CV...

journal_title：Stroke

authors： Théaudin M,Crassard I,Bresson D,Saliou G,Favrole P,Vahedi K,Denier C,Bousser MG

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to measure the overall rate of usage of tissue-type plasminogen activator (tPA) for ischemic stroke at academic medical centers, and to determine whether ethnicity was associated with usage. METHODS:Between June and December 1999, 42 academic medical centers in the United States each i...

journal_title：Stroke

authors： Johnston SC,Fung LH,Gillum LA,Smith WS,Brass LM,Lichtman JH,Brown AN

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The use of lithium as a neuroprotective agent has been demonstrated using various models in which improvements in infarct size, DNA damage, and neurological function were reported. We further investigated neurohemodynamic aspects of the treatment-associated recovery by assessing the therapeutic e...

journal_title：Stroke

authors： Kim YR,van Meer MP,Tejima E,Murata Y,Mandeville JB,Dai G,Chuang DM,Rosen BR,Lo EH

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Outcome measurement fidelity within and between sites of multi-site, randomized, clinical trials is an essential element to meaningful trial outcomes. As important are the methods developed for randomized, clinical trials that can have practical utility for clinical practice. A standardized measu...

journal_title：Stroke

authors： Sullivan KJ,Tilson JK,Cen SY,Rose DK,Hershberg J,Correa A,Gallichio J,McLeod M,Moore C,Wu SS,Duncan PW

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We hypothesize that in acute middle cerebral artery stroke, thrombus lengths measured in thin-slice nonenhanced CT images define a limit beyond which systemic thrombolysis will fail to recanalize occluded arteries. METHODS:In 138 patients who presented with acute middle cerebral artery stroke an...

journal_title：Stroke

authors： Riedel CH,Zimmermann P,Jensen-Kondering U,Stingele R,Deuschl G,Jansen O

更新日期：2011-06-01 00:00:00

abstract：:Hemodynamic changes were examined with an ultrasonic Doppler flowmeter and with a sound-spectrograph in 5 patients with internal carotid giant aneurysms or with recurrent laryngeal cancer undergoing gradual carotid occlusion. The ultrasonic Doppler technique was useful for preoperative assessment of intracranial cross...

journal_title：Stroke

authors： Moritake K,Handa H,Yonekawa Y,Takebe Y,Kishimoto S,Makimoto K

更新日期：1981-03-01 00:00:00

abstract：:We determined the immediate effects of pentoxifylline on cerebral blood flow in 10 patients with cerebrovascular disease; four received 400 mg and six received 800 mg pentoxifylline orally. Regional cerebral blood flow was measured before (baseline) and 2, 4, and 6 hours after pentoxifylline administration using the x...

journal_title：Stroke

authors： Bowton DL,Stump DA,Prough DS,Toole JF,Lefkowitz DS,Coker L

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Outcome after acute stroke is determined to a large extent by poststroke complications. Nutritional status and metabolic balance may substantially contribute to outcome after stroke. Key mechanisms of stroke pathophysiology can induce systemic catabolic imbalance with impaired metabolic efficienc...

journal_title：Stroke

authors： Scherbakov N,Dirnagl U,Doehner W

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Many studies have reported frequent cognitive deficits associated with subarachnoid hemorrhage (SAH) and aneurysm repair. One study found more severe cognitive deficits after clipping than coiling of aneurysms, raising the possibility that deficits are due to surgery instead of SAH itself. This p...

journal_title：Stroke

authors： Tuffiash E,Tamargo RJ,Hillis AE

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Experimental stroke models are essential to study in vivo pathophysiological processes of focal cerebral ischemia. In this study, an embolic stroke model in rats was applied (1) to characterize early development of regional cerebral blood flow and metabolism with positron emission tomography (PET...

journal_title：Stroke

authors： Walberer M,Backes H,Rueger MA,Neumaier B,Endepols H,Hoehn M,Fink GR,Schroeter M,Graf R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Warfarin reduces stroke risk in studies of predominantly white patients with atrial fibrillation (AF). Whether nonwhites also have lower rates of stroke while treated with warfarin is unclear. METHODS:A multiethnic stroke-free cohort hospitalized with nonrheumatic AF was identified in a large he...

journal_title：Stroke

authors： Shen AY,Yao JF,Brar SS,Jorgensen MB,Wang X,Chen W

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic postconditioning, a brief episode of ischemia after a prolonged ischemic insult, has been found to reduce the delayed neuronal loss after stroke. However, the mechanisms underlying such endogenous neuroprotective strategy remain obscure. In this study, we try to explore the excitatory po...

journal_title：Stroke

authors： Liu J,Xu Q,Wang H,Wang R,Hou XY

更新日期：2013-07-01 00:00:00

abstract：:Regional cerebral ischemia was produced by common carotid artery occlusion in gerbils and by middle cerebral artery occlusion in dogs, cats, and squirrel monkeys. Anesthesia was induced with either pentobarbital or halothane and maintained for two to three hours after vessel occlusion. In acute studies, the effect of ...

journal_title：Stroke

authors： Michenfelder JD,Milde JH

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of the present study was to investigate the effects of normobaric oxygen (NBO) therapy on T2*-weighted images of intracranial hemorrhages (ICHs). METHODS:Two common models of ICH were performed in mice, and longitudinal T2*-weighted images of the hematomas were acquired under normoxia or...

journal_title：Stroke

authors： Gaberel T,Gakuba C,Hebert M,Montagne A,Agin V,Rubio M,Emery E,Vivien D,Gauberti M

更新日期：2013-12-01 00:00:00

abstract：:A case of simultaneous rupture of two intracranial aneurysms is reported. This is a rare event, and we found no CT reports of such a case. This case points out that the usual assumption of a single aneurysm rupture in a patient with multiple aneurysms may be erroneous and difficult to diagnose angiographically, but ma...

journal_title：Stroke

authors： Joslyn JN,Williams JP,White JL,White RL

更新日期：1985-05-01 00:00:00

abstract：:Seventy-four patients with hypertensive putaminal hemorrhage (HPH) were followed at least 6 months after treatment and estimated by ADL. They were graded according to the state of consciousness on admission. The grading consists of 6 grades: Grade 1, fully conscious; Grade 2, somnolent; Grade 3, stuporous; Grade 4, se...

journal_title：Stroke

authors： Waga S,Yamamoto Y

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To elucidate how the motor pathways rewire the denervated tissue after stroke, we investigated remodeling of the corticospinal tract (CST) in transgenic mice with yellow fluorescent protein CST labeling in conjunction with transsynaptic pseudorabies virus retrograde tracing. METHODS:Adult male C...

journal_title：Stroke

authors： Liu Z,Zhang RL,Li Y,Cui Y,Chopp M

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The success of gait rehabilitation after stroke depends on active walking exercises. However, the disabling after-effects of stroke often make such exercises impossible at the onset of therapy. To facilitate treadmill training of paraparetic patients, a robot-driven gait orthosis (Lokomat) was de...

journal_title：Stroke

authors： Husemann B,Müller F,Krewer C,Heller S,Koenig E

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Montreal Cognitive Assessment (MoCA) and Addenbrooke's Cognitive Examination-Revised (ACE-R) are proposed as short cognitive tests for use after stroke, but there are few published validations against a neuropsychological battery. We studied the relationship between MoCA, ACE-R, Mini-Mental S...

journal_title：Stroke

authors： Pendlebury ST,Mariz J,Bull L,Mehta Z,Rothwell PM

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accumulating evidence indicates that a variety of infections contribute to the pathogenesis of atherosclerosis, but there is controversy concerning the impact of Helicobacter pylori infections in atherosclerosis. METHODS:We evaluated seropositivity to H pylori and to its cytotoxin-associated gen...

journal_title：Stroke

authors： Mayr M,Kiechl S,Mendall MA,Willeit J,Wick G,Xu Q

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The lipid peroxidation inhibitor U-101033E was examined for effects on cerebral blood flow (CBF), cortical tissue hemoglobin oxygen saturation (HbSo2), and neuronal damage. METHODS:Fifteen minutes of global cerebral ischemia was induced by two-vessel occlusion and hypobaric hypotension. Wistar r...

journal_title：Stroke

authors： Soehle M,Heimann A,Kempski O

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The onset of spontaneous intracerebral hemorrhage (ICH) is often accompanied by transient blood pressure (BP) elevation. The prognostic value and the determinants of this BP reaction have not entirely been solved, and the present study was focused on these questions. METHODS:From 1985 to 1991 in...

journal_title：Stroke

authors： Fogelholm R,Avikainen S,Murros K

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We describe the clinical, diagnostic, and outcome features of a cohort of white patients with idiopathic moyamoya disease treated in a German institution. METHODS:Our cohort included 21 white patients with moyamoya disease. Clinical and diagnostic features were obtained by retrospective chart re...

journal_title：Stroke

authors： Kraemer M,Heienbrok W,Berlit P

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent Icelandic studies have demonstrated linkage for common forms of stroke to chromosome 5q12 and association between phosphodiesterase4D (PDE4D) and ischemic stroke. Using a candidate region approach, we wanted to test the validity of these findings in a different population from northern Swe...

journal_title：Stroke

authors： Nilsson-Ardnor S,Wiklund PG,Lindgren P,Nilsson AK,Janunger T,Escher SA,Hallbeck B,Stegmayr B,Asplund K,Holmberg D

更新日期：2005-08-01 00:00:00

abstract：:Non-invasive vascular testing has proven to be an effective means of identifying patients with significant extracranial carotid artery disease. Such tests can yield valuable physiologic data in patients with TIAs and can identify patients with soft signs who may have significant carotid artery disease and who may be c...

journal_title：Stroke

authors： Goran A,Moore G

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pial arterioles transiently dilate during cortical spreading depression (CSD), although the mechanisms are unclear. We tested the hypothesis that increased production of nitric oxide (NO) promotes arteriolar dilation. METHODS:Urethane-anesthetized rabbits were equipped with cranial windows, and ...

journal_title：Stroke

authors： Colonna DM,Meng W,Deal DD,Busija DW

更新日期：1994-12-01 00:00:00