Postischemic production of eicosanoids in gerbil brain.

abstract：:Background and Purpose- Although older age is one of the most important risk factor for stroke in atrial fibrillation (AF), the appropriate age threshold (eg, CHA2DS2-VASc score [congestive heart failure, hypertension, age ≥75 years (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vas...

journal_title：Stroke

authors： Kim TH,Yang PS,Yu HT,Jang E,Uhm JS,Kim JY,Pak HN,Lee MH,Joung B,Lip GYH

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pneumonia has been estimated to occur in about one third of patients after acute stroke. Only limited data are available on stroke-associated pneumonia (SAP) in specialized neurological intensive care units (NICUs). METHODS:We enrolled 124 patients with acute stroke who were treated at our unive...

journal_title：Stroke

authors： Hilker R,Poetter C,Findeisen N,Sobesky J,Jacobs A,Neveling M,Heiss WD

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prominent posterior cerebral artery (PCA) laterality upon 3-dimensional time-of-flight magnetic resonance angiography is often encountered in patients with middle cerebral artery occlusion. We hypothesized that this sign is correlated with improved functional outcome in patients with middle cereb...

journal_title：Stroke

authors： Ichijo M,Miki K,Ishibashi S,Tomita M,Kamata T,Fujigasaki H,Mizusawa H

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and is linked with mortality, cardiovascular events, and stroke. However, the role of FGF23 as a risk factor for subclinical cerebrovascular damage is unclear. METHODS:We used multivariable linear and logistic regressio...

journal_title：Stroke

authors： Wright CB,Shah NH,Mendez AJ,DeRosa JT,Yoshita M,Elkind MS,Sacco RL,DeCarli C,Rundek T,Silverberg S,Dong C,Wolf M

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The outcomes of carotid endarterectomy (CEA) are, in addition to patient baseline characteristics, highly dependent on the safety of the surgical procedure. During the successive stages of the operation, transcranial Doppler (TCD) monitoring of the middle cerebral artery (MCA) was used to assess ...

journal_title：Stroke

authors： Ackerstaff RG,Moons KG,van de Vlasakker CJ,Moll FL,Vermeulen FE,Algra A,Spencer MP

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autopsy series of patients with AIDS have found a 4% to 29% prevalence of cerebral infarction. Little is known of the prevalence of cerebral infarction when not associated with non-HIV central nervous system (CNS) infection, lymphoma, or cardioembolic sources. Clinical correlation has seldom been...

journal_title：Stroke

authors： Connor MD,Lammie GA,Bell JE,Warlow CP,Simmonds P,Brettle RD

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study is to investigate whether apocynin, an NADPH oxidase inhibitor, attenuates vasospasm after experimental subarachnoid hemorrhage (SAH) in rats. METHODS:Rats were subjected to endovascular perforation of the right anterior cerebral artery or sham surgery. Beginning 2 hour...

journal_title：Stroke

authors： Zheng JS,Zhan RY,Zheng SS,Zhou YQ,Tong Y,Wan S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Mechanisms involved in stroke progression are incompletely understood. Ischemic brain injury is characterized by acute local inflammatory response mediated by cytokines. Anti-inflammatory cytokines act in a feedback loop to inhibit continued proinflammatory cytokine production. We assessed the implication of...

journal_title：Stroke

authors： Vila N,Castillo J,Dávalos A,Esteve A,Planas AM,Chamorro A

更新日期：2003-03-01 00:00:00

abstract：:Nonvalvular atrial fibrillation (NVAF) can be a source of cardiogenic brain embolism. We retrospectively reviewed the clinical features of 56 patients with acute brain infarction and NVAF. Based on clinical criteria, 35 infarcts (63%) were classified as probably embolic, 13 infarcts (23%) as probably nonembolic and 8 ...

journal_title：Stroke

authors： Hart RG,Coull BM,Hart D

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral ischemia and stroke are leading causes of morbidity and mortality. An approach to protecting the brain during ischemia is to try to increase the delivery of oxygen via the residual blood flow through and around ischemic tissue. To test this hypothesis, we used a novel oxygen delivery age...

journal_title：Stroke

authors： Watson JC,Doppenberg EM,Bullock MR,Zauner A,Rice MR,Abraham D,Young HF

更新日期：1997-08-01 00:00:00

abstract：:To study the effects of antithrombotic therapy in experimental stroke, we have characterized a baboon model of acute cerebrovascular thrombosis. In this model an inflatable silastic balloon cuff has been implanted by transorbital approach around the right middle cerebral artery (MCA), proximal to the take-off of the l...

journal_title：Stroke

authors： Del Zoppo GJ,Copeland BR,Harker LA,Waltz TA,Zyroff J,Hanson SR,Battenberg E

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We developed and validated a simple algorithm to predict the risk of hematoma growth in acute spontaneous intracerebral hemorrhage (ICH) to better inform clinicians and researchers in their efforts to improve outcomes for patients. METHODS:We analyzed data from the computed tomography substudies...

journal_title：Stroke

authors： Wang X,Arima H,Al-Shahi Salman R,Woodward M,Heeley E,Stapf C,Lavados PM,Robinson T,Huang Y,Wang J,Delcourt C,Anderson CS,INTERACT Investigators.

更新日期：2015-02-01 00:00:00

abstract：:A 51-yearold man with moderate intermittent hypertension had a rapidly progressive, profound dementia in the absence of significant localizing neurological signs. Postmortem examination disclosed the vascular alterations and diffuse white matter degeneration which characterize subcortical arteriosclerotic encephalopat...

journal_title：Stroke

authors： Burger PC,Burch JG,Kunze U

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although both general and abdominal adiposity are well-established risk factors for coronary heart disease, their associations with stroke are less well characterized, particularly in generally lean Asian populations. METHODS:We evaluated associations of body mass index (BMI), waist-hip ratio (W...

journal_title：Stroke

authors： Zhang X,Shu XO,Gao YT,Yang G,Li H,Zheng W

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In 6% to 9% of patients with subarachnoid hemorrhage (SAH), familial aggregation occurs; truly familial cases carry a worse prognosis than sporadic cases and raise the question of screening. If relatives have died from SAH, the family history is often the only available clue to the diagnosis, but...

journal_title：Stroke

authors： Bromberg JE,Rinkel GJ,Algra A,Greebe P,Beldman T,van Gijn J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Optimizing prehospital stroke care is important because effective treatments for acute stroke require a narrow therapeutic time window. We developed a smartphone-assisted prehospital medical information system (SPMIS) to facilitate research on prehospital stroke care. METHODS:Prehospital medical...

journal_title：Stroke

authors： Nakae T,Kataoka H,Kuwata S,Iihara K

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To define desirable target low-density lipoprotein (LDL) cholesterol levels for the prevention of stroke recurrence, a post hoc analysis was performed in the J-STARS study (Japan Statin Treatment Against Recurrent Stroke). METHODS:Subjects (n=1578) were divided into groups based on mean value of...

journal_title：Stroke

authors： Hosomi N,Kitagawa K,Nagai Y,Nakagawa Y,Aoki S,Nezu T,Kagimura T,Maruyama H,Origasa H,Minematsu K,Uchiyama S,Matsumoto M,J-STARS Collaborators.

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Exogenously administered fructose-1,6-bisphosphate reduces neuronal injury from hypoxic or ischemic brain insults. To test the hypothesis that fructose-1,6-bisphosphate prevents changes in intracellular calcium ([Ca2+]i) and high-energy phosphate levels, we measured [Ca2+]i, intracellular pH (pHi...

journal_title：Stroke

authors： Bickler PE,Kelleher JA

更新日期：1992-11-01 00:00:00

abstract：:Weights of matching right and left middle or posterior cerebral arteries and their main branches from the same animal were compared 8-10 weeks after unilateral denervation by superior cervical ganglionectomy. When compared in pairs, the denervated arterial systems weighed significantly less (mean 85%) than their inner...

journal_title：Stroke

authors： Bevan RD,Tsuru H,Bevan JA

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The association among socioeconomic status, quality of care, and clinical outcome after stroke remains poorly understood. In a Danish nationwide follow-up study, we examined whether socioeconomic-related differences in acute stroke care occur and, if so, whether they explain socioeconomic differe...

journal_title：Stroke

authors： Langagergaard V,Palnum KH,Mehnert F,Ingeman A,Krogh BR,Bartels P,Johnsen SP

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A right-to-left shunt can be identified by contrast transcranial Doppler ultrasonography (c-TCD) at rest and/or after a Valsalva maneuver (VM) or by arterial blood gas (ABG) measurement. We assessed the influence of controlled strain pressures and durations during VM on the right-to-left passage ...

journal_title：Stroke

authors： Devuyst G,Piechowski-Józwiak B,Karapanayiotides T,Fitting JW,Kémeny V,Hirt L,Urbano LA,Arnold P,van Melle G,Despland PA,Bogousslavsky J

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:High-sensitivity C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) are hypothesized to be biomarkers of systemic inflammation and risk of myocardial infarction (MI) and stroke. Little is known, however, about the stability of these markers over time, and in particul...

journal_title：Stroke

authors： Elkind MS,Leon V,Moon YP,Paik MC,Sacco RL

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose was to investigate the occurrence of self-reported falls in people with stroke at 3, 6, and 12 months and 6 years post stroke and predictors for falls during 6 years. METHODS:A prospective study involving 121 people with stroke. Data were obtained through structured interviews and as...

journal_title：Stroke

authors： Minet LR,Peterson E,von Koch L,Ytterberg C

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke MRI protocols provide useful information about underlying vessel pathologies in the anterior circulation by means of intracranial time-of-flight angiography. However, these protocols mostly fail in the posterior circulation to differentiate between congenital variants and secondary thrombo...

journal_title：Stroke

authors： Freund W,Kassubek J,Aschoff AJ,Huber R

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The association between minor ST-T abnormalities and stroke incidence has not been well elucidated. We sought to examine the relationship between nonspecific minor or major ST-T abnormalities and the incidence of stroke among Japanese men and women. METHODS:A 15.4-year prospective study was cond...

journal_title：Stroke

authors： Ohira T,Iso H,Imano H,Kitamura A,Sato S,Nakagawa Y,Naito Y,Sankai T,Tanigawa T,Yamagishi K,Iida M,Shimamoto T

更新日期：2003-12-01 00:00:00

abstract：:Background and Purpose- Multifaceted quality improvement interventions of stroke care have been shown to improve hospital personnel adherence to evidence-based performance measures and subsequent stroke outcomes. This study aimed to evaluate the cost-effectiveness of a multifaceted quality improvement intervention for...

journal_title：Stroke

authors： Pan Y,Zhang L,Li Z,Meng X,Wang Y,Li H,Liu L,Wang Y

更新日期：2020-04-01 00:00:00

abstract：:Leukoaraiosis is a common finding in stroke patients and has been strongly associated with risk of incident stroke and dementia. Leukoaraiosis may also be an independent predictor of stroke outcomes. There is increasing evidence from neuroimaging to support the concept that some leukoaraiosis is caused by white matter...

journal_title：Stroke

authors： Smith EE

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Treatment with the ketone body precursor 1,3-butanediol has been suggested to ameliorate hypoxic/ischemic brain damage. Butanediol could provide an alternative energy substrate for the brain, thereby decreasing the amount of glycolytically produced lactate. Hyperglycemia aggravates brain damage a...

journal_title：Stroke

authors： Lundgren J,Smith ML,Mans AM,Siesjö BK

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral microbleeds are frequently seen in the general elderly population, but it is unknown at what rate they occur with aging and whether once present can disappear over time. METHODS:As part of the Rotterdam Scan Study, 831 persons (mean age, 68.5 years) underwent repeated brain MRI with a m...

journal_title：Stroke

authors： Poels MM,Ikram MA,van der Lugt A,Hofman A,Krestin GP,Breteler MM,Vernooij MW

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The sensitivity of the brain to brief periods of profound ischemia or prolonged periods of modest ischemia mandates an aggressive approach to acute stroke care. Past studies have shown that many stroke patients do not receive acute care in an urgent and timely fashion. The formation of acute stro...

journal_title：Stroke

authors： Alberts MJ,Chaturvedi S,Graham G,Hughes RL,Jamieson DG,Krakowski F,Raps E,Scott P

更新日期：1998-11-01 00:00:00