Lipohyalinosis and miliary microaneurysms causing cerebral hemorrhage in a patient with moyamoya. A clinicopathological study.

Abstract:

:Moyamoya is an intriguing and controversial syndrome. This patient study serves to align the pathophysiology of intracranial hemorrhage in moyamoya with the cerebral vascular disease seen with hypertension, or aging. The historical evidence linking lipohyalinosis and microaneurysms to cerebral hemorrhage is reviewed, the pathogenesis of this angiopathy is discussed, and explanations considered for its association with the vascular pattern of moyamoya. We propose that hemodynamics, genetics or both are among the primary operant etiologic factors.

journal_name

Stroke

journal_title

Stroke

authors

Mauro AJ,Johnson ES,Chikos PM,Alvord EC Jr

doi

10.1161/01.str.11.4.405

subject

Has Abstract

pub_date

1980-07-01 00:00:00

pages

405-12

issue

4

eissn

0039-2499

issn

1524-4628

journal_volume

11

pub_type

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