Evidence of corticospinal tract injury at midbrain in patients with subarachnoid hemorrhage.

abstract：:The purpose of this study was to develop an animal model that could be used to test the ability of Doppler ultrasound to detect arterial emboli composed of materials that are often involved in cerebral emboli. Emboli introduced into the rabbit aorta via the left renal artery consisted of clotted whole blood, platelets...

journal_title：Stroke

authors： Russell D,Madden KP,Clark WM,Sandset PM,Zivin JA

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:cerebral small vessel disease (SVD) is the most common cause of vascular dementia. Interest in the use of surrogate markers is increasing. The aims of this study were to determine if brain volume was different between patients with SVD and control subjects, whether it correlated with cognition in...

journal_title：Stroke

authors： Nitkunan A,Lanfranconi S,Charlton RA,Barrick TR,Markus HS

更新日期：2011-01-01 00:00:00

abstract：:Background and Purpose- Although obesity is an established risk factor for cardiovascular disease and stroke, studies have shown evidence of an obesity paradox-a protective effect of obesity in patients who already have these disease states. Data on the obesity paradox in intracerebral hemorrhage is limited. Methods- ...

journal_title：Stroke

authors： Persaud SR,Lieber AC,Donath E,Stingone JA,Dangayach NS,Zhang X,Mocco J,Kellner CP

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) is associated with a temporal pattern of stroke incidence. We hypothesized that natural oscillations in gene expression controlling circadian rhythm affect the severity of neuronal injury. We moreover predict that heme oxygenase-1 (HO-1/Hmox1) and its product carbon ...

journal_title：Stroke

authors： Schallner N,Lieberum JL,Gallo D,LeBlanc RH 3rd,Fuller PM,Hanafy KA,Otterbein LE

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A supraphysiological amount of vitamin E in the standard diet of laboratory animals may provide partial protection against cerebral ischemic damage in stroke models. The aim of the present study was to test the effect of dietary vitamin E on infarct volume in rats subjected to permanent focal cer...

journal_title：Stroke

authors： van der Worp HB,Bär PR,Kappelle LJ,de Wildt DJ

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The introduction of cereal grain folic acid fortification in 1998 has reduced homocyst(e)ine (tHcy) concentrations in the US population. We performed a case-control study to determine the risk of stroke and transient ischemic attack (TIA) associated with tHcy and low vitamin status in a postforti...

journal_title：Stroke

authors： Kelly PJ,Shih VE,Kistler JP,Barron M,Lee H,Mandell R,Furie KL

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is expanding literature to show that certain patients admitted during the weekend have worse outcomes than similar patients admitted during the week. Although many clinicians have hypothesized the presence of this "weekend effect" with patients with intracerebral hemorrhage, there is a pauc...

journal_title：Stroke

authors： Crowley RW,Yeoh HK,Stukenborg GJ,Medel R,Kassell NF,Dumont AS

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative stress is known to be involved in ischemic stroke. Intense interest is drawn to the therapeutic potential of Chinese herbs on ischemic stroke because many of them contain antioxidant properties. Leonurine, 1 of the active compounds from purified Herba Leonuri, was studied to evaluate it...

journal_title：Stroke

authors： Loh KP,Qi J,Tan BK,Liu XH,Wei BG,Zhu YZ

更新日期：2010-11-01 00:00:00

abstract：:Brief episodes of ischemia can protect against subsequent damaging ischemic events; however, the molecular mechanisms responsible for protection are poorly understood. Identifying genes involved in this process could provide insight into cell survival and treatment of stroke. We developed a murine model of ischemic pr...

journal_title：Stroke

authors： Stenzel-Poore MP,Stevens SL,Simon RP

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autopsy series of patients with AIDS have found a 4% to 29% prevalence of cerebral infarction. Little is known of the prevalence of cerebral infarction when not associated with non-HIV central nervous system (CNS) infection, lymphoma, or cardioembolic sources. Clinical correlation has seldom been...

journal_title：Stroke

authors： Connor MD,Lammie GA,Bell JE,Warlow CP,Simmonds P,Brettle RD

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Desaturation during swallowing may help to identify aspiration in stroke patients. This study investigated pulse oximetry, bedside swallowing assessment (BSA), and videofluoroscopy as tests for detecting aspiration after stroke. METHODS:Swallowing was assessed in 189 stroke patients (mean+/-SD a...

journal_title：Stroke

authors： Ramsey DJ,Smithard DG,Kalra L

更新日期：2006-12-01 00:00:00

abstract：:Background and Purpose- Intracerebral hemorrhage (ICH) has a poorer prognosis than acute ischemic stroke (AIS). However, clinician perception of prognosis may influence treatment decisions and adversely affect outcome. On acute CT, the conspicuity of ICH compared with AIS may lead clinicians to overestimate severity a...

journal_title：Stroke

authors： Tilling EJ,El Tawil S,Muir KW

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To improve reproducibility and reliability in the identification of embolic signals detected with the use of Doppler ultrasound, many studies have used an intensity threshold. However, variable thresholds between 3 and 12 dB have been used, and often the method of measurement of intensity is not ...

journal_title：Stroke

authors： Markus HS,Molloy J

更新日期：1997-04-01 00:00:00

abstract：:In the period 1977-1982, the Danish National Patient Register recorded 1000 cases of cerebral thromboembolic attacks among women 15-44 years of age, and 971 cases among men of the same age. Cerebral infarction accounted for 70% of cases and transient ischemic attacks (TIA) for the remaining 30%. By analysing this mate...

journal_title：Stroke

authors： Lidegaard O,Soe M,Andersen MV

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Determinants of long-term outcome are not well defined in minor stroke patients. This study aims to evaluate which factors are independent long-term predictors of death and major stroke recurrence in a cohort of minor ischemic strokes. METHODS:A cohort of 322 patients with first-ever minor ische...

journal_title：Stroke

authors： Prencipe M,Culasso F,Rasura M,Anzini A,Beccia M,Cao M,Giubilei F,Fieschi C

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic stroke patients often have intracranial atherosclerosis (ICAS), despite heterogeneity in the cause of stroke. We tested the hypothesis that ICAS burden can independently reflect the risk of long-term vascular outcome. METHODS:This was a retrospective cohort study analyzing data from a p...

journal_title：Stroke

authors： Kim BS,Chung PW,Park KY,Won HH,Bang OY,Chung CS,Lee KH,Kim GM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The majority of patients enrolled in SWIFT PRIME trial (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke) had computed tomographic perfusion (CTP) imaging before randomization; 34 patients were randomized after magnetic resonance imaging...

journal_title：Stroke

authors： Menjot de Champfleur N,Saver JL,Goyal M,Jahan R,Diener HC,Bonafe A,Levy EI,Pereira VM,Cognard C,Yavagal DR,Albers GW

更新日期：2017-06-01 00:00:00

abstract：:A 25-year-old black man with sarcoidosis presented with transient ischemic attacks followed by sudden, persistent right hemiparesis. He gave a history of recent, recurrent lower motor neuron facial palsy. Computed tomography demonstrated an infarct in the left internal capsule. Chest x-ray film showed bilateral hilar ...

journal_title：Stroke

authors： Brown MM,Thompson AJ,Wedzicha JA,Swash M

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to evaluate the impact of new treatments by examining the changes between 1990 to 1991 and 2000 to 2001 in in-hospital mortality rates and hospital charges in adult patients with stroke. METHODS:From the Nationwide Inpatient Survey, the largest all-payer inpatient c...

journal_title：Stroke

authors： Qureshi AI,Suri MF,Nasar A,Kirmani JF,Ezzeddine MA,Divani AA,Giles WH

更新日期：2007-07-01 00:00:00

abstract：:Though unilateral blood distribution of the vertebral artery has not been studied in humans, it is significant when considering the ischemic events especially embolic occlusion in vertebrobasilar system. To clarify the blood distribution, Krypton-81m was continuously infused into the vertebral arteries of 10 patients....

journal_title：Stroke

authors： Taki W,Handa H,Higa T,Tanada S,Fukuyama H,Fujita T,Yonekawa Y,Kameyama M,Torizuka K

更新日期：1984-05-01 00:00:00

abstract：:A 34-year-old, single Japanese woman with active Takayasu's disease presented with stenosed bilateral common carotid arteries, subtotal occlusion of the left subclavian artery, and complete occlusion of the ipsilateral proximal vertebral artery, as demonstrated by angiography. A right subclavian-left vertebral bypass ...

journal_title：Stroke

authors： Ishikawa K,Yonekawa Y

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thick cisternal clot on CT is a well-recognized risk factor for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH). Whether intraventricular hemorrhage (IVH) or intracerebral hemorrhage (ICH) predisposes to DCI is unclear. The Fisher CT grading scale identifies thick SAH but does...

journal_title：Stroke

authors： Claassen J,Bernardini GL,Kreiter K,Bates J,Du YE,Copeland D,Connolly ES,Mayer SA

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perfusion-weighted magnetic resonance imaging (PWI) is a reliable and semiquantitative method for estimating cerebral hemodynamics. We sought to evaluate the potential of PWI for assessing cerebral blood flow (CBF) and metabolism compared with positron emission tomography (PET) in patients with c...

journal_title：Stroke

authors： Kajimoto K,Moriwaki H,Yamada N,Hayashida K,Kobayashi J,Miyashita K,Naritomi H

更新日期：2003-07-01 00:00:00

abstract：:Background and Purpose- Hemispheric stroke studies associating lateropulsion (pusher syndrome) with the location of brain lesions have had mixed results from small, unmatched samples. This study was designed to determine whether lateropulsion localizes to specific brain regions across patients with stroke using a case...

journal_title：Stroke

authors： Babyar SR,Smeragliuolo A,Albazron FM,Putrino D,Reding M,Boes AD

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron overload has been associated with greater oxidative stress and brain injury in experimental cerebral ischemia and reperfusion. This study investigates whether high serum ferritin levels, as an index of increased cellular iron stores, are associated with poor outcome, hemorrhagic transformati...

journal_title：Stroke

authors： Millan M,Sobrino T,Castellanos M,Nombela F,Arenillas JF,Riva E,Cristobo I,García MM,Vivancos J,Serena J,Moro MA,Castillo J,Dávalos A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Numerous studies indicate that mild hypothermia provides substantial neuroprotection. However, current systems transfer insufficient heat to rapidly vary core temperature. We thus evaluated the safety and efficacy of endovascular cooling and rewarming for the induction and reversal of hypothermia...

journal_title：Stroke

authors： Dae MW,Gao DW,Ursell PC,Stillson CA,Sessler DI

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Enhanced angiogenesis facilitates neurovascular remodeling processes and promotes brain functional recovery after stroke. Previous studies from our laboratory demonstrated that valproate (VPA), a histone deacetylase inhibitor, protects against experimental brain ischemia. The present study invest...

journal_title：Stroke

authors： Wang Z,Tsai LK,Munasinghe J,Leng Y,Fessler EB,Chibane F,Leeds P,Chuang DM

更新日期：2012-09-01 00:00:00

abstract：:The methionine analogue methionine sulfoximine was administered to 10 rats 24 hours before occlusion of the proximal left middle cerebral artery. Three days later the rats were decapitated and the brain infarct volumes were compared with those in 10 control rats that received saline before middle cerebral artery occlu...

journal_title：Stroke

authors： Swanson RA,Shiraishi K,Morton MT,Sharp FR

更新日期：1990-02-01 00:00:00

abstract：:Background and Purpose- The complexity and heterogeneity of stroke, as well as the associated comorbidities, may render neuroprotective drugs less efficacious in clinical practice. Therefore, the development of targeted therapies to specific patient subsets has become a high priority in translational stroke research. ...

journal_title：Stroke

authors： Jiang Y,Liu N,Wang Q,Yu Z,Lin L,Yuan J,Guo S,Ahn BJ,Wang XJ,Li X,Lo EH,Sun X,Wang X

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction. We aimed to determine which baseline clinical and radiological parameters predict development of CED in patients treated with...

journal_title：Stroke

authors： Thorén M,Azevedo E,Dawson J,Egido JA,Falcou A,Ford GA,Holmin S,Mikulik R,Ollikainen J,Wahlgren N,Ahmed N

更新日期：2017-09-01 00:00:00