Cerebrovascular disease in Utah, 1968--1971.

abstract：BACKGROUND AND PURPOSE:Exogenous delivery of vascular endothelial growth factor gene (VEGF) may provide a useful approach to the treatment of brain ischemia. We investigated the use of a hypoxia-responsive element to control VEGF expression given for neuroprotection. METHODS:Three groups (n=36) of mice received AAVH9-...

journal_title：Stroke

authors： Shen F,Su H,Fan Y,Chen Y,Zhu Y,Liu W,Young WL,Yang GY

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chronic ocular ischemia is a rare form of ischemia of the eye in patients with carotid artery occlusion (CAO). The early and often asymptomatic stage of chronic ocular ischemia is referred to as venous stasis retinopathy (VSR). The aim of this study was to gain insight into the prevalence, cause,...

journal_title：Stroke

authors： Klijn CJ,Kappelle LJ,van Schooneveld MJ,Hoppenreijs VP,Algra A,Tulleken CA,van Gijn J

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Persons with early stages of chronic kidney disease, defined by a decreased glomerular filtration rate (GFR), have an increased risk of cardiovascular disease. It is unclear whether decreased GFR is a risk factor for stroke. We assessed the association between GFR and stroke in a prospective popu...

journal_title：Stroke

authors： Bos MJ,Koudstaal PJ,Hofman A,Breteler MM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Heart of Glass (HEG) receptor binds KRIT1 and functions with KRIT1, CCM2, and PDCD10 in a common signaling pathway required for heart and vascular development. Mutations in KRIT1, CCM2, and PDCD10 also underlie human cerebral cavernous malformation (CCM) and postnatal loss of these genes in t...

journal_title：Stroke

authors： Zheng X,Riant F,Bergametti F,Myers CD,Tang AT,Kleaveland B,Pan W,Yang J,Tournier-Lasserve E,Kahn ML

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patent foramen ovale (PFO) is significantly associated with cryptogenic stroke (CS). However, even in patients with CS, a PFO can be an incidental finding. We sought to estimate the probability that a PFO in a patient with CS is incidental. METHODS:A systematic search identified 23 case-control ...

journal_title：Stroke

authors： Alsheikh-Ali AA,Thaler DE,Kent DM

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiology of stroke in the young is different from that in older patients and remains unknown in almost one third of the cases. To gain further insight into both pathogenic and etiologic determinants, we prospectively studied a large number of consecutive young adults with focal cerebral ische...

journal_title：Stroke

authors： Carolei A,Marini C,Ferranti E,Frontoni M,Prencipe M,Fieschi C

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study was designed to assess the quality of life after an active poststroke period of rehabilitation and to investigate the possibility of a return to a working environment for those still of working age. METHODS:The study was conducted on 180 consecutive patients affected by stroke who wer...

journal_title：Stroke

authors： Angeleri F,Angeleri VA,Foschi N,Giaquinto S,Nolfe G

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is known that atherosclerosis does not involve both carotid arteries to the same extent. Pathological investigations have demonstrated that lesions develop in regions of low wall shear stress. The aims of the present study were to verify the degree of carotid atherosclerosis asymmetry in a pop...

journal_title：Stroke

authors： Gnasso A,Irace C,Carallo C,De Franceschi MS,Motti C,Mattioli PL,Pujia A

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study aimed to identify aspects of the caregiving situation contributing to family caregivers' psychological well-being. METHODS:Longitudinal cohort study with structured quantitative interviews 1, 3, 6, and 12 months post stroke. A subset of participants also completed surveys 18 and 24 mo...

journal_title：Stroke

authors： Cameron JI,Stewart DE,Streiner DL,Coyte PC,Cheung AM

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous studies suggest that the management of coronary artery disease differs for women compared with men. We examined this issue for ischemic cerebrovascular disease. METHODS:We reviewed the use of angiography and carotid endarterectomy among patients discharged from Connecticut hospitals dur...

journal_title：Stroke

authors： Patrick SJ,Concato J,Viscoli C,Chyatte D,Brass LM

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preclinical data suggest that cell-based therapies have the potential to improve stroke outcomes. METHODS:Eighteen patients with stable, chronic stroke were enrolled in a 2-year, open-label, single-arm study to evaluate the safety and clinical outcomes of surgical transplantation of modified bon...

journal_title：Stroke

authors： Steinberg GK,Kondziolka D,Wechsler LR,Lunsford LD,Coburn ML,Billigen JB,Kim AS,Johnson JN,Bates D,King B,Case C,McGrogan M,Yankee EW,Schwartz NE

更新日期：2016-07-01 00:00:00

abstract：UNLABELLED:The pathophysiology of postischemic encephalopathy is complex, and includes tissue acidosis, edema, hypoperfusion, membrane dysfunction, impaired energy production, and possibly hypermetabolism. We tested the hypothesis that this multifactorial clinical problem must be approached with multifaceted therapy, w...

journal_title：Stroke

authors： Gisvold SE,Safar P,Rao G,Moossy J,Kelsey S,Alexander H

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke leads to a reduction in bone mineral density, altered calcium homeostasis, and an increase in hip fractures. Vitamin D deficiency is well documented in long-term stroke survivors and is associated with post-stroke hip fractures. Less is known regarding levels in acute stroke. METHODS:We c...

journal_title：Stroke

authors： Poole KE,Loveridge N,Barker PJ,Halsall DJ,Rose C,Reeve J,Warburton EA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The prevalence of constipation after stroke varies from 30% to 60%. The incidence of new-onset constipation during the early stage of stroke remains uncertain. The present study was designed to investigate the prevalence of new-onset constipation, its risk factors, and its impact on stroke outcom...

journal_title：Stroke

authors： Su Y,Zhang X,Zeng J,Pei Z,Cheung RT,Zhou QP,Ling L,Yu J,Tan J,Zhang Z

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Kawasaki disease is a febrile disease of children notable for systemic vasculitis. There have been many previous reports of various complications, including disorders of the central nervous system. We evaluated cerebral perfusion during the acute stage in patients with Kawasaki disease. METHODS:...

journal_title：Stroke

authors： Ichiyama T,Nishikawa M,Hayashi T,Koga M,Tashiro N,Furukawa S

更新日期：1998-07-01 00:00:00

abstract：:Background and Purpose- Imaging is frequently used to select acute stroke patients for intra-arterial therapy. Quantitative cerebral blood flow can be measured noninvasively with arterial spin labeling magnetic resonance imaging. Cerebral blood flow levels in the contralateral (unaffected) hemisphere may affect capaci...

journal_title：Stroke

authors： Thamm T,Guo J,Rosenberg J,Liang T,Marks MP,Christensen S,Do HM,Kemp SM,Adair E,Eyngorn I,Mlynash M,Jovin TG,Keogh BP,Chen HJ,Lansberg MG,Albers GW,Zaharchuk G

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is no consensus on whether anticoagulation should be continued or temporarily stopped in patients suffering acute ischemic stroke while using anticoagulation. We assessed treatment variations and outcomes in these patients. METHODS:Post hoc analysis of PASS (Preventive Antibiotics in Strok...

journal_title：Stroke

authors： Groot AE,Vermeij JM,Westendorp WF,Nederkoorn PJ,van de Beek D,Coutinho JM

更新日期：2018-07-01 00:00:00

abstract：:In children with Moyamoya disease, transient ischemic attacks often occur during hyperventilation, and the frequency of attacks usually decreases with advancing age. To elucidate the mechanism of the attacks, the regional cerebral blood flow was measured during rest and/or hyperventilation in children aged 3-16 with M...

journal_title：Stroke

authors： Tagawa T,Naritomi H,Mimaki T,Yabuuchi H,Sawada T

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence suggests that the protease-activated receptor-1 (PAR-1), a thrombin receptor, mediates neuronal injury in experimental cerebral ischemia. The present study investigated whether PAR-1 plays a role in brain injury after global cerebral ischemia. METHODS:Adult male wild-type or PAR-1 knock...

journal_title：Stroke

authors： Wang J,Jin H,Hua Y,Keep RF,Xi G

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The impact of asymptomatic coronary artery disease on the risk of major vascular events in patients with cerebral infarction is unknown. METHODS:Four hundred five patients with acute cerebral infarction underwent carotid, femoral artery, thoracic, and abdominal aorta ultrasound examination. Of 3...

journal_title：Stroke

authors： Amarenco P,Lavallée PC,Labreuche J,Ducrocq G,Juliard JM,Feldman L,Cabrejo L,Meseguer E,Guidoux C,Adraï V,Ratani S,Kusmierek J,Lapergue B,Klein IF,Gongora-Rivera F,Jaramillo A,Abboud H,Olivot JM,Mazighi M,Touboul PJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous studies have demonstrated that echocardiographic left ventricular mass (LVM) is an independent risk factor for stroke in whites. Despite the greater burden of stroke, the echocardiographic predictors of stroke in African Americans remain poorly understood. METHODS:This investigation is ...

journal_title：Stroke

authors： Fox ER,Taylor HA Jr,Benjamin EJ,Ding J,Liebson PR,Arnett D,Quin EM,Skelton TN

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with carotid occlusive disease and stage 2 cerebral hemodynamic failure, characterized by an increased oxygen extraction fraction (OEF) as measured by positron emission tomography (PET) and otherwise known as misery perfusion, have a high risk of cerebral ischemia and subsequent stroke. ...

journal_title：Stroke

authors： Imaizumi M,Kitagawa K,Hashikawa K,Oku N,Teratani T,Takasawa M,Yoshikawa T,Rishu P,Ohtsuki T,Hori M,Matsumoto M,Nishimura T

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A previous trial (the Clomethiazole Acute Stroke Study) generated the hypothesis that clomethiazole is effective in patients with a major ischemic stroke (total anterior circulation syndrome), and this was tested in the present study. METHODS:A total of 1198 patients with major ischemic stroke a...

journal_title：Stroke

authors： Lyden P,Shuaib A,Ng K,Levin K,Atkinson RP,Rajput A,Wechsler L,Ashwood T,Claesson L,Odergren T,Salazar-Grueso E,CLASS-I\/H\/T Investigators.

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mild hypothermia has been shown to ameliorate neuronal damage due to cerebral ischemia. In our study, the influence of mild-to-moderate hypothermia was examined in a rabbit model of focal cerebral ischemia. METHODS:After 4 hours of permanent ischemia induced by occlusion of the anterior and midd...

journal_title：Stroke

authors： Lo EH,Steinberg GK

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Robust measures of functional outcome are required to determine treatment effects in stroke trials. Of the various measures available, the Barthel index (BI) is one of the more prevalent. We aimed to describe validity, reliability, and responsiveness (clinimetric properties) of the BI in stroke t...

journal_title：Stroke

authors： Quinn TJ,Langhorne P,Stott DJ

更新日期：2011-04-01 00:00:00

abstract：:Choline concentration is rate limiting in the synthesis of acetylcholine. There is a negative arteriovenous difference for choline concentration across the brain, indicating the steady output of choline from this organ. Cerebral ischemia may increase extracellular choline concentration by interfering with its removal ...

journal_title：Stroke

authors： Scremin OU,Jenden DJ

更新日期：1989-01-01 00:00:00

abstract：:There have been numerous failures in the field of acute stroke therapy over many years, but the first large clinical trial showing preliminary indications of efficacy and safety of a neuroprotective drug, NXY-059, has now been fully reported. If confirmed, it will mean that a second therapy for acute stroke has been i...

journal_title：Stroke

authors： Zivin JA

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The method described provides a rational means for determining whether to institute chronic anticoagulation to prevent stroke in patients with chronic atrial fibrillation under a variety of clinical circumstances. SUMMARY OF COMMENT:The concept of expected value is used in conjunction with data from clinica...

journal_title：Stroke

authors： Nadeau SE

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Visual assessment of cerebrospinal fluid (CSF) for xanthochromia (yellow color) is practiced by the majority of laboratories worldwide as a means of diagnosing intracranical bleeds. METHODS:Colorimetric and spectrophotometric analysis of CSF samples for recognizing the presence of bilirubin either in low co...

journal_title：Stroke

authors： Petzold A,Keir G,Sharpe TL

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Traditional vascular risk factors do not completely explain the asymmetry, racial, and sex differences in carotid artery disease. Carotid anatomy and geometry may play a role in the pathogenesis of internal carotid artery (ICA) stenosis, but their effects are unknown. We hypothesized that carotid...

journal_title：Stroke

authors： Phan TG,Beare RJ,Jolley D,Das G,Ren M,Wong K,Chong W,Sinnott MD,Hilton JE,Srikanth V

更新日期：2012-06-01 00:00:00