Diverging trends in cerebrovascular disease and ischaemic heart disease mortality.

abstract：BACKGROUND AND PURPOSE:The CHA2DS2-VASc score aims to improve risk stratification of ischemic stroke among patients with atrial fibrillation to identify those who can safely forego oral anticoagulation. Oral anticoagulation treatment guidelines remain uncertain for CHA2DS2-VASc score of 1. We conducted a systematic rev...

journal_title：Stroke

authors： Joundi RA,Cipriano LE,Sposato LA,Saposnik G,Stroke Outcomes Research Working Group.

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The PIWI-interacting RNA (piRNA) is the most predominant RNA species in eukaryotes. The piRNA are a class of noncoding RNAs that bind and degrade the RNA formed by the transposons to control the transposon-induced gene mutations. The role of piRNA after focal ischemia is not yet evaluated. METHO...

journal_title：Stroke

authors： Dharap A,Nakka VP,Vemuganti R

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study examines whether lesion shape documented on magnetic resonance diffusion-weighted imaging during acute stroke improves the prediction of the final infarct volume compared with lesion volume only. METHODS:Diffusion-weighted imaging data and clinical information were retrospectively rev...

journal_title：Stroke

authors： Frindel C,Rouanet A,Giacalone M,Cho TH,Østergaard L,Fiehler J,Pedraza S,Baron JC,Wiart M,Berthezène Y,Nighoghossian N,Rousseau D

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Animal data suggest the use of beta-human chorionic gonadotropin followed by erythropoietin to promote brain repair after stroke. The current study directly translated these results by evaluating safety of this sequential growth factor therapy through a 3-center, single-dose, open-label, noncontr...

journal_title：Stroke

authors： Cramer SC,Fitzpatrick C,Warren M,Hill MD,Brown D,Whitaker L,Ryckborst KJ,Plon L

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:If it could be determined whether cerebral blood flow can be maintained (autoregulated) during transient falls in arterial blood pressure, we might be able to identify patients with carotid stenosis who are at risk of stroke. However, conventional methods of determining autoregulation in such pat...

journal_title：Stroke

authors： White RP,Markus HS

更新日期：1997-07-01 00:00:00

abstract：:Stroke is a complex disease, with both genetic and environmental factors having a role in its pathogenesis. A review of past studies shows some evidence of genetic influences in the development of stroke. This is supported by studies of cardiovascular disease, which indicate major genetic influences at several levels ...

journal_title：Stroke

authors： Alberts MJ

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary arteriopathy, which mainly involves the brain causing stroke and dementia. Mice expressing the mutated protein display early dysfunction in vasoreactivity in resistance arteries, b...

journal_title：Stroke

authors： Stenborg A,Kalimo H,Viitanen M,Terent A,Lind L

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mild hypothermia is possibly the single most effective method of cerebroprotection developed to date. However, many questions regarding mild hypothermia remain to be addressed before its potential implementation in the treatment of human stroke. Here we report the results of 2 studies designed to...

journal_title：Stroke

authors： Maier CM,Ahern Kv,Cheng ML,Lee JE,Yenari MA,Steinberg GK

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is unclear whether intracerebral hemorrhage (ICH) is associated with dynamic or static exercise. Our aim was to assess whether such an association exists. METHODS:A case-control study was undertaken involving 331 consecutive cases of primary ICH and 331 age- and sex-matched community-based ne...

journal_title：Stroke

authors： Thrift AG,Donnan GA,McNeil JJ

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fever after aneurysmal subarachnoid hemorrhage is associated with poor outcome. Because hydrocephalus and extravasated blood may influence thermoregulation, we determined whether these factors increase the risk for fever after subarachnoid hemorrhage. METHODS:Fever within 14 days (subdivided int...

journal_title：Stroke

authors： Dorhout Mees SM,Luitse MJ,van den Bergh WM,Rinkel GJ

更新日期：2008-07-01 00:00:00

abstract：:We studied ultrastructurally cerebral perforating arteries in 60 stroke-prone spontaneously hypertensive rats (SHRSP), which were sequentially killed at 4-52 weeks of age before showing symptoms of stroke. Another 24 SHRSP were killed soon after they showed symptoms of cerebral infarction. The initial vascular lesions...

journal_title：Stroke

authors： Tagami M,Nara Y,Kubota A,Sunaga T,Maezawa H,Fujino H,Yamori Y

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke patients without evidence of arterial occlusion may not be suitable candidates for thrombolytic therapy. In our study, we investigated the outcomes of patients with negative CT angiography results for arterial occlusion. METHODS:The study included patients treated within 3 hours after sym...

journal_title：Stroke

authors： Mikulik R,Goldemund D,Reif M,Aulicky P,Krupa P

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous tissue plasminogen activator (tPA) is an economically worthwhile but underused treatment option for acute ischemic stroke. We sought to identify the extent of tPA use in Canadian medical centers and the potential savings associated with increased use nationally and by province. METHO...

journal_title：Stroke

authors： Yip TR,Demaerschalk BM

更新日期：2007-06-01 00:00:00

abstract：:Experimental subarachnoid hemorrhage was induced in 52 adult male Wistar rats by microsurgical transclival basilar artery puncture. Telencephalic blood flow measured in 24 rats with subarachnoid hemorrhage was compared with that in 23 sham-operated rats and 10 unoperated control rats using the [14C]butanol indicator f...

journal_title：Stroke

authors： Kader A,Krauss WE,Onesti ST,Elliott JP,Solomon RA

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Outcome after mechanical thrombectomy for ischemic stroke may be influenced by blood pressure (BP). This study aims to assess the association of BP changes during general anesthesia versus conscious sedation with functional outcome after mechanical thrombectomy. METHODS:SIESTA (Sedation vs Intub...

journal_title：Stroke

authors： Schönenberger S,Uhlmann L,Ungerer M,Pfaff J,Nagel S,Klose C,Bendszus M,Wick W,Ringleb PA,Kieser M,Möhlenbruch MA,Bösel J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thick cisternal clot on CT is a well-recognized risk factor for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH). Whether intraventricular hemorrhage (IVH) or intracerebral hemorrhage (ICH) predisposes to DCI is unclear. The Fisher CT grading scale identifies thick SAH but does...

journal_title：Stroke

authors： Claassen J,Bernardini GL,Kreiter K,Bates J,Du YE,Copeland D,Connolly ES,Mayer SA

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) growth predicts mortality and functional outcome. We hypothesized that irregular hematoma shape and density heterogeneity, reflecting active, multifocal bleeding or a variable bleeding time course, would predict ICH growth. METHODS:Three raters examined baseline su...

journal_title：Stroke

authors： Barras CD,Tress BM,Christensen S,MacGregor L,Collins M,Desmond PM,Skolnick BE,Mayer SA,Broderick JP,Diringer MN,Steiner T,Davis SM,Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators.

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Coffee consumption has been inconsistently associated with stroke incidence and mortality in previous studies. We investigated the association between coffee consumption and stroke incidence in the Swedish Mammography Cohort. METHODS:We prospectively followed of 34,670 women without a history of...

journal_title：Stroke

authors： Larsson SC,Virtamo J,Wolk A

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral microbleeds are frequently seen in the general elderly population, but it is unknown at what rate they occur with aging and whether once present can disappear over time. METHODS:As part of the Rotterdam Scan Study, 831 persons (mean age, 68.5 years) underwent repeated brain MRI with a m...

journal_title：Stroke

authors： Poels MM,Ikram MA,van der Lugt A,Hofman A,Krestin GP,Breteler MM,Vernooij MW

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In children having suffered from neonatal arterial ischemic stroke, the relationship between contralesional hand performance and structural changes in brain areas remote from the infarct site was examined. METHODS:Using voxel-based morphometry, we correlated contralesional gross manual dexterity...

journal_title：Stroke

authors： Dinomais M,Hertz-Pannier L,Groeschel S,Delion M,Husson B,Kossorotoff M,Renaud C,Chabrier S,The Tich SN,AVCnn Study Group.

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The natural product baicalein is a specific inhibitor of 12/15-lipoxygenase, but it also has antioxidant properties. The current study was designed to test if the neuroprotective properties of baicalein are related to its lipoxygenase inhibition. METHODS:The presence of 12/15-lipoxygenase in the...

journal_title：Stroke

authors： van Leyen K,Kim HY,Lee SR,Jin G,Arai K,Lo EH

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ultrasound of carotid arteries provides measures of intima media thickness (IMT) and plaque, both widely used as surrogate measures of cardiovascular disease. Although IMT and plaques are highly intercorrelated, the relationship between carotid plaque and IMT and cardiovascular disease has been c...

journal_title：Stroke

authors： Johnsen SH,Mathiesen EB,Joakimsen O,Stensland E,Wilsgaard T,Løchen ML,Njølstad I,Arnesen E

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) is associated with a temporal pattern of stroke incidence. We hypothesized that natural oscillations in gene expression controlling circadian rhythm affect the severity of neuronal injury. We moreover predict that heme oxygenase-1 (HO-1/Hmox1) and its product carbon ...

journal_title：Stroke

authors： Schallner N,Lieberum JL,Gallo D,LeBlanc RH 3rd,Fuller PM,Hanafy KA,Otterbein LE

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The prevalence of constipation after stroke varies from 30% to 60%. The incidence of new-onset constipation during the early stage of stroke remains uncertain. The present study was designed to investigate the prevalence of new-onset constipation, its risk factors, and its impact on stroke outcom...

journal_title：Stroke

authors： Su Y,Zhang X,Zeng J,Pei Z,Cheung RT,Zhou QP,Ling L,Yu J,Tan J,Zhang Z

更新日期：2009-04-01 00:00:00

abstract：:The frequency of angiographically defined asymptomatic CAD in patients with carotid disease is 40%. Although the prognosis of patients with asymptomatic 1-vessel or 2-vessel CAD is good (annual cardiac mortality rate less than 2%), the prognosis of asymptomatic 3-vessel disease or left main CAD is substantially less f...

journal_title：Stroke

authors： Chimowitz MI,Mancini GB

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke incidence and mortality are declining rapidly in developed countries. Little data on ethnic-specific stroke recurrence trends exist. Fourteen-year stroke recurrence trend estimates were evaluated in Mexican Americans and non-Hispanic whites in a population-based study. METHODS:Recurrent s...

journal_title：Stroke

authors： Sozener CB,Lisabeth LD,Shafie-Khorassani F,Kim S,Zahuranec DB,Brown DL,Skolarus LE,Burke JF,Kerber KA,Meurer WJ,Case E,Morgenstern LB

更新日期：2020-08-01 00:00:00

abstract：:Clinicopathologic correlations were reviewed in 100 cases of recent cerebral infarctions in the internal carotid artery distribution. The most frequent cause of death was transtentorial herniation, followed in frequency by pneumonia, cardiac causes, and pulmonary embolism. Thirty-six percent of all patients and 47% of...

journal_title：Stroke

authors： Bounds JV,Wiebers DO,Whisnant JP,Okazaki H

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid plaque composition is a major determinant of cerebrovascular events. In the present analysis, we evaluated the relationship between intraplaque hemorrhage (IPH) and a thin/ruptured fibrous cap (TRFC) in moderately stenosed carotid arteries and cerebral infarcts on MRI in the ipsilateral h...

journal_title：Stroke

authors： de Rotte AA,Truijman MT,van Dijk AC,Liem MI,Schreuder FH,van der Kolk AG,de Kruijk JR,Daemen MJ,van der Steen AF,de Borst GJ,Luijten PR,Nederkoorn PJ,Kooi ME,van der Lugt A,Hendrikse J

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Whether newly diagnosed atrial fibrillation (nAF) after stroke reflects underlying heart disease and represents an increased risk of cardioembolic stroke, or whether it is triggered by neurogenic mechanisms remains uncertain. We investigated, whether cardiovascular risk factors and echocardiograp...

journal_title：Stroke

authors： Rizos T,Horstmann S,Dittgen F,Täger T,Jenetzky E,Heuschmann P,Veltkamp R

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron is an essential element for the human body. It has, however, been suggested that excessive iron stores may increase the risk of vascular disease. So far, epidemiologic studies on stroke are sparse. METHODS:We studied the association between iron status and stroke risk in a population-based ...

journal_title：Stroke

authors： van der A DL,Grobbee DE,Roest M,Marx JJ,Voorbij HA,van der Schouw YT

更新日期：2005-08-01 00:00:00