Incremental predictive value of carotid inflammation in acute ischemic stroke.

abstract：BACKGROUND AND PURPOSE:Systemic administration of Toll-like receptor (TLR) 4 and TLR9 agonists before cerebral ischemia have been shown to reduce ischemic injury by reprogramming the response of the brain to stroke. Our goal was to explore the mechanism of TLR-induced neuroprotection by determining whether a TLR7 agoni...

journal_title：Stroke

authors： Leung PY,Stevens SL,Packard AE,Lessov NS,Yang T,Conrad VK,van den Dungen NN,Simon RP,Stenzel-Poore MP

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Current guidelines suggest that cardiac arrest (CA) survivors should be ventilated with 100% O(2) after resuscitation. Breathing 100% O(2) may worsen neurological outcome after experimental CA. This study tested the hypothesis that graded reoxygenation, with oximetry guidance, can safely reduce F...

journal_title：Stroke

authors： Balan IS,Fiskum G,Hazelton J,Cotto-Cumba C,Rosenthal RE

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Specialized management of patients with stroke is not available in all hospitals. We evaluated whether prehospital management in the Stroke Emergency Mobile (STEMO) improves the triage of patients with stroke. METHODS:STEMO is an ambulance staffed with a specialized stroke team and equipped with...

journal_title：Stroke

authors： Wendt M,Ebinger M,Kunz A,Rozanski M,Waldschmidt C,Weber JE,Winter B,Koch PM,Freitag E,Reich J,Schremmer D,Audebert HJ,STEMO Consortium.

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Abnormalities in endogenous fibrinolysis are associated with an increased risk for stroke in men and older adults. We tested the hypothesis that elevated plasma tissue plasminogen activator (tPA) antigen, a marker for impaired endogenous fibrinolysis, is an independent risk factor for stroke in y...

journal_title：Stroke

authors： Macko RF,Kittner SJ,Epstein A,Cox DK,Wozniak MA,Wityk RJ,Stern BJ,Sloan MA,Sherwin R,Price TR,McCarter RJ,Johnson CJ,Earley CJ,Buchholz DW,Stolley PD

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence is accumulating regarding the prognostic influence of hyperglycemia in patients with acute ischemic stroke. However, the level associated with poor outcome is unknown. Our objectives were to establish the capillary glucose threshold with the highest predictive accuracy of poor outcome an...

journal_title：Stroke

authors： Fuentes B,Castillo J,San José B,Leira R,Serena J,Vivancos J,Dávalos A,Nuñez AG,Egido J,Díez-Tejedor E,Stroke Project of the Cerebrovascular Diseases Study Group, Spanish Society of Neurology.

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The influence of stroke lateralization on functional and cardiovascular outcome after stroke is not well established. We evaluated the influence of hemispheric lateralization among patients enrolled in prospective acute stroke trials. METHODS:We obtained data from the VISTA database for acute st...

journal_title：Stroke

authors： Fink JN,Frampton CM,Lyden P,Lees KR,Virtual International Stroke Trials Archive Investigators.

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In acute stroke patients with intracranial vessel occlusion, angiographic demonstration of antegrade contrast opacification distal to the occlusion site (termed the "clot outline sign") has been associated with higher rates of vessel recanalization. We sought to determine whether antegrade flow c...

journal_title：Stroke

authors： Frölich AM,Psychogios MN,Klotz E,Schramm R,Knauth M,Schramm P

更新日期：2012-11-01 00:00:00

abstract：:Arteriolar diameters and venular erythrocyte velocities in the small pial vessels on the surface of the cat brain were measured by TV methods during induced epileptic seizures through a cranial window. Grand mal seizures maximally dilated arterioles and increased venular erythrocyte velocity up to 400%. High positive ...

journal_title：Stroke

authors： Myers RR,Intaglietta M

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few studies are available that have addressed the prevalence of early-onset dementia (EOD), including early-onset Alzheimer disease and other forms of dementia in Japan. METHODS:A 2-step postal survey was sent to all of the 2475 institutions providing medical or care services for individuals wit...

journal_title：Stroke

authors： Ikejima C,Yasuno F,Mizukami K,Sasaki M,Tanimukai S,Asada T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) monitoring of mean blood flow velocity (mV) during head-upright tilt can allow testing of cerebral autoregulation. Nonetheless, head-upright tilt can induce changes in the ventilation-perfusion relationship and/or respiratory activity that might influence TCD data. MET...

journal_title：Stroke

authors： Cencetti S,Bandinelli G,Lagi A

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these varia...

journal_title：Stroke

authors： Woodward M,Lowe GD,Campbell DJ,Colman S,Rumley A,Chalmers J,Neal BC,Patel A,Jenkins AJ,Kemp BE,MacMahon SW

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clear elucidation of the exact pathophysiological mechanisms of motor weakness in patients with subarachnoid hemorrhage has not yet been achieved. We attempted to investigate injury to the corticospinal tract in patients with subarachnoid hemorrhage using diffusion tensor imaging. METHODS:Twenty...

journal_title：Stroke

authors： Yeo SS,Choi BY,Chang CH,Kim SH,Jung YJ,Jang SH

更新日期：2012-08-01 00:00:00

abstract：:Moyamoya is an intriguing and controversial syndrome. This patient study serves to align the pathophysiology of intracranial hemorrhage in moyamoya with the cerebral vascular disease seen with hypertension, or aging. The historical evidence linking lipohyalinosis and microaneurysms to cerebral hemorrhage is reviewed, ...

journal_title：Stroke

authors： Mauro AJ,Johnson ES,Chikos PM,Alvord EC Jr

更新日期：1980-07-01 00:00:00

abstract：:Recent data strongly suggest that repetitive ischemic episodes have an adverse cumulative effect on development of edema and tissue damage. We wanted to assess further whether special risks such as exacerbation of extracellular acidification reflecting progressive exhaustion of the capacity to buffer H+ in the extrace...

journal_title：Stroke

authors： Matsumoto T,Obrenovitch TP,Parkinson NA,Symon L

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Obstructive sleep apnea, a condition associated with chronic intermittent hypoxia (CIH), carries an increased risk of stroke. However, CIH has been reported to either increase or decrease brain injury in models of focal cerebral ischemia. The factors determining the differential effects of CIH on...

journal_title：Stroke

authors： Jackman KA,Zhou P,Faraco G,Peixoto PM,Coleman C,Voss HU,Pickel V,Manfredi G,Iadecola C

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increasing attention has been paid to associations between cognitive dysfunction and brain microbleeds (MBs). Because all previous studies have investigated patients with neurological disorders, we examined subjects without neurological disorder in order to clarify pathogenic relationships. METH...

journal_title：Stroke

authors： Yakushiji Y,Nishiyama M,Yakushiji S,Hirotsu T,Uchino A,Nakajima J,Eriguchi M,Nanri Y,Hara M,Horikawa E,Kuroda Y

更新日期：2008-12-01 00:00:00

abstract：:Background and Purpose- The purpose of this study was to conduct a meta-analysis of CVOTs (cardiovascular outcome trials) to evaluate the effect of glucagon-like peptide-1 receptor agonists therapy in reducing the risk of stroke in patients with type 2 diabetes mellitus. Methods- PubMed and other electronic sources we...

journal_title：Stroke

authors： Bellastella G,Maiorino MI,Longo M,Scappaticcio L,Chiodini P,Esposito K,Giugliano D

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid angioplasty and stenting (CAS) is associated with higher risk of periprocedural stroke and death when compared with carotid endarterectomy (CEA). By contrast, the risk of myocardial infarction (MI) was higher after CEA than after CAS in randomized trials. However, numbers were small, and ...

journal_title：Stroke

authors： Boulanger M,Camelière L,Felgueiras R,Berger L,Rerkasem K,Rothwell PM,Touzé E

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis for acute ischemic stroke is usually based on clinical assessment, blood test results, and CT findings. Intravenous thrombolysis of stroke mimics may occur but has not been studied in detail. METHODS:We determined frequency, clinical characteristics, and outcome of mimic...

journal_title：Stroke

authors： Winkler DT,Fluri F,Fuhr P,Wetzel SG,Lyrer PA,Ruegg S,Engelter ST

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pathophysiology of borderzone infarcts is not well understood. We investigated whether combined diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) could identify pathophysiologically meaningful categories of borderzone infarcts. METHODS:Seventeen patients with borderzone i...

journal_title：Stroke

authors： Chaves CJ,Silver B,Schlaug G,Dashe J,Caplan LR,Warach S

更新日期：2000-05-01 00:00:00

abstract：:Background and Purpose- Despite evidence to support the prescription of antihypertensive medications before hospital discharge to promote medication adherence and prevent recurrent events, many patients with stroke miss out on these medications at discharge. We aimed to examine patient, clinical, and system-level diff...

journal_title：Stroke

authors： Dalli LL,Kim J,Thrift AG,Andrew NE,Lannin NA,Anderson CS,Grimley R,Katzenellenbogen JM,Boyd J,Lindley RI,Pollack M,Jude M,Durairaj R,Shah D,Cadilhac DA,Kilkenny MF

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mechanical thrombectomy (MT) is the recommended treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion. However, despite a high rate of reperfusion, the clinical response to successful MT remains highly variable in the early time window where optimal imaging sel...

journal_title：Stroke

authors： Olivot JM,Albucher JF,Guenego A,Thalamas C,Mlynash M,Rousseau V,Drif A,Christensen S,Sommet A,Viguier A,Darcourt J,Calvière L,Menegon P,Raposo N,Januel AC,Bonneville F,Tourdias T,Mazighi M,Sibon I,Albers GW,Cognar

更新日期：2021-01-01 00:00:00

abstract：:Background and Purpose- Intracranial thrombi can be characterized according to their permeability as measured by contrast agent penetration. Thrombus composition and its associated pathogenesis are important factors affecting treatment and secondary prevention. We aimed to explore the histopathologic factors explainin...

journal_title：Stroke

authors： Berndt M,Friedrich B,Maegerlein C,Moench S,Hedderich D,Lehm M,Zimmer C,Straeter A,Poppert H,Wunderlich S,Schirmer L,Oberdieck P,Kaesmacher J,Boeckh-Behrens T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the efficacy of endovascular treatment (EVT) in patients with anterior circulation ischemic stroke (AIS) is well documented, early neurological deterioration after EVT remains a serious issue associated with poor outcome. Besides obvious causes, such as lack of reperfusion, procedural co...

journal_title：Stroke

authors： Girot JB,Richard S,Gariel F,Sibon I,Labreuche J,Kyheng M,Gory B,Dargazanli C,Maier B,Consoli A,Daumas-Duport B,Lapergue B,Bourcier R,ETIS Investigators*.

更新日期：2020-10-01 00:00:00

abstract：:Background and Purpose- Blood pressure (BP) variability may increase the risk of stroke and dementia. It remains inconclusive whether BP variability is associated with cerebral small vessel disease, a common and potentially devastating subclinical disease that contributes significantly to both stroke and dementia. Met...

journal_title：Stroke

authors： Ma Y,Song A,Viswanathan A,Blacker D,Vernooij MW,Hofman A,Papatheodorou S

更新日期：2020-01-01 00:00:00

abstract：:In an attempt to determine the usefulness of evoked potentials as a measure of focal cerebral ischemia, we examined somatosensory evoked potentials (SEP's) and morphological neuronal changes in cats following unilateral middle cerebral artery (MCA) occlusion. Fifteen adult cats underwent transorbital occlusion of the ...

journal_title：Stroke

authors： Steinberg GK,Gelb AW,Lam AM,Manninen PH,Peerless SJ,Rassi Neto A,Floyd P

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Efficacy of endovascular treatment (EVT) for ischemic stroke because of large vessel occlusion may depend on patients' age and stroke severity; we, therefore, developed a prognosis score based on these variables and examined whether EVT efficacy differs between patients with good, intermediate, o...

journal_title：Stroke

authors： Le Bouc R,Clarençon F,Meseguer E,Lapergue B,Consoli A,Turc G,Naggara O,Duong DL,Servan J,Reiner P,Labeyrie MA,Fisselier M,Blanc R,Farhat W,Pires C,Zuber M,Obadia M,Mazighi M,Pico F,Mas JL,Amarenco P,Samson Y,P

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Redundant internal carotid arteries have been considered a risk factor in tonsillectomy, adenoidectomy, and surgical treatment of peritonsillar abscess and also a potentially treatable cause of stroke. However, an association between internal carotid artery redundancy and spontaneous dissection h...

journal_title：Stroke

authors： Barbour PJ,Castaldo JE,Rae-Grant AD,Gee W,Reed JF 3rd,Jenny D,Longennecker J

更新日期：1994-06-01 00:00:00

abstract：:Various studies indicate that after a latent interval, a progressive focal deterioration of microvascular perfusion can develop in zones of acute damage to the central nervous system (CNS). In order to obtain reliable information concerning the possibility of platelet participation in this phenomenon, platelet deposit...

journal_title：Stroke

authors： Obrenovitch TP,Hallenbeck JM

更新日期：1985-03-01 00:00:00

abstract：:Platelet activating factor, a potent inducer of in vivo platelet activation and thrombosis, has been shown to be excessively active in acute ischemic stroke patients. Therefore, we studied the effect of aspirin/dipyridamole therapy in inhibiting platelet activating factor-induced platelet activation in acute ischemic ...

journal_title：Stroke

authors： Joseph R,Welch KM,D'Andrea G

更新日期：1989-05-01 00:00:00