Abstract:
:Unilateral stimulation of the cervical sympathetic in dogs had no effect on cerebral blood flow (CBF) measured by the venous outflow technique. Since this technique measured CBF from both cerebral hemispheres, small changes induced by unilateral stimulation could have been masked by a large constant CBF measured from the contralteral hemisphere. To test this possibility the effect of simultaneous bilateral sympathetic stimulation was studied when the dog was breathing either normal air or a gas mixture of 10%CO2. During normocapnia, no changes in CBF occurred; during hypercapnia CBF increased 19% following passively the increase in blood pressure. These data indicate that bilateral stimulation of extracranial sympathetic nerves does not exert a significant effect on CBF. We show mathematically and experimentally that unoccluded anastomses will cause CBF to appear to decrease in response to sympathetic stimulation. This may explain why others have observed changes in CBF during sympathetic stimulation.
journal_name
Strokejournal_title
Strokeauthors
Barber BJ,Martin JS,Rapela CEdoi
10.1161/01.str.9.1.29subject
Has Abstractpub_date
1978-01-01 00:00:00pages
29-34issue
1eissn
0039-2499issn
1524-4628journal_volume
9pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:The use of bare metal stents to treat symptomatic intracranial stenosis may be associated with significant restenosis rates. The advent of drug-eluting stents (DESs) in the coronary circulation has resulted in a reduction of restenosis rates. We report our technical success rate and short-term re...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/01.STR.0000242481.38262.7b
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Potassium intake has been inconsistently associated with risk of stroke. Our aim was to conduct a meta-analysis of prospective studies to assess the relation between potassium intake and stroke risk. METHODS:Pertinent studies were identified by a search of PubMed from January 1966 through March ...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/STROKEAHA.111.622142
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In primary intracerebral hemorrhage, the presence of contrast extravasation after computed tomographic angiography (CTA), termed the spot sign, predicts hematoma expansion and mortality. Because the biological underpinnings of the spot sign are not fully understood, we investigated whether the ra...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.115.009659
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The inflammatory response within cerebral infarcts may have an influence on tissue damage. Since old animals with an impaired immune response have decreased inflammation after experimental cerebral infarction, we postulated that female animals with an increased immune response will have an increa...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.3.498
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The neck clipping of cerebral aneurysms is a well-established treatment for subarachnoid hemorrhage (SAH) caused by aneurysmal rupture. However, it is still unclear how great a risk of recurrence patients with a successfully treated aneurysm carry over a long-term period. METHODS:Of 425 patients...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.29.12.2511
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The applicability of a novel differentiation technique in embolus detection based on the coincidence principle and using a multigate probe was evaluated in this study. METHODS:According to the coincidence method, high-intensity transients should only be classified as microembolic signals if they...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.4.683
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several studies have found a morning peak in onset of stroke. A similar peak has been suggested for subarachnoid hemorrhage (SAH), which seems in contradiction with the physical activities associated with aneurysmal rupture. Most studies included only a few patients with SAH. We analyzed time of ...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.28.4.805
更新日期:1997-04-01 00:00:00
abstract::Radiolabelled misonidazole, a radiosensitizing drug that binds to viable hypoxic tumor cells, may be useful in identifying hypoxic cells in cerebrovascular disease. Its potential was investigated in the gerbil stroke model. Biodistribution of [3H]misonidazole was measured in normal gerbils and animals that had been su...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.168
更新日期:1987-01-01 00:00:00
abstract::A 26-year-old woman had a peripartum venous thrombotic stroke involving the right parietal lobe. The initial thrombus was present only in the right channel of a congenitally bifurcated superior sagittal sinus. This diagnosis and subsequent thrombus extension were readily shown by magnetic resonance imaging in contrast...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.3.396
更新日期:1991-03-01 00:00:00
abstract::We devised the present experiments to assess the effects of ischemia on the production of dopamine in the caudate nucleus of spontaneously hypertensive stroke-resistant rats. Ringer's solution was continuously perfused at a rate of 10 microliters/min through 0.2-mm-diameter dialysis tubing implanted in the rat's cauda...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.12.1540
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Diffusion-weighted MRI can demonstrate decreases of the apparent diffusion coefficient (ADC) of brain tissue water shortly after the onset of ischemia. To further elucidate underlying mechanisms, this study extended diffusion assessment to intracellular metabolites in rat brain in vivo before, du...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.10.1930
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Patients with carotid occlusive disease and stage 2 cerebral hemodynamic failure, characterized by an increased oxygen extraction fraction (OEF) as measured by positron emission tomography (PET) and otherwise known as misery perfusion, have a high risk of cerebral ischemia and subsequent stroke. ...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.0000027638.19392.7e
更新日期:2002-09-01 00:00:00
abstract::There have been numerous failures in the field of acute stroke therapy over many years, but the first large clinical trial showing preliminary indications of efficacy and safety of a neuroprotective drug, NXY-059, has now been fully reported. If confirmed, it will mean that a second therapy for acute stroke has been i...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.STR.0000252090.44428.82
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Previously, we have shown that hyperthermia significantly increased neuronal damage after ischemic injury in a focal embolic model of stroke in rats. In the present study, we examined the effects of hyperthermia on the efficacy of thrombolytic therapy in this stroke model. METHODS:In part A, eff...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000155684.20864.58
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Leptin is the major adipose hormone that regulates body weight and energy expenditure by activating leptin receptors in the hypothalamus. Leptin receptors are also present in other cell types, and a potent antiapoptotic effect for leptin has recently been reported. We investigated whether leptin ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.482786
更新日期:2007-08-01 00:00:00
abstract::Regional cerebral blood flow, blood volume, fractional oxygen extraction, and oxygen consumption were measured by positron emission tomography in 4 stroke patients prior to and 6 months following omental transposition surgery. Preoperatively, 3 patients showed the typical picture of established infarction with a match...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.46
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Thrombus within the carotid artery usually occurs in vessels with severe atherosclerotic disease and may embolize to cause transient ischemic attacks and cerebral infarctions. The risk factors for carotid artery thrombus formation in the absence of atherosclerosis are not well characterized. A case series is...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.5.1002
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) is the only type of stroke with female predominance, suggesting that reproductive factors may play a role in the etiology. We conducted a population-based study to examine the influence of parity on the risk of SAH in women. METHODS:We linked data from 3 national Sw...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000105933.16654.B4
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We earlier reported that risk factors for stroke prepare brain stem tissue for a modified Shwartzman reaction, including the development of ischemia and hemorrhage and the production of tumor necrosis factor-alpha, after a provocative dose of lipopolysaccharide. In the present study, we sought to...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.24.6.880
更新日期:1993-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Perihematomal edema (PHE) is associated with poor outcomes after intracerebral hemorrhage (ICH). PHE evolves in the early period after ICH, providing a therapeutic target and window for intervention. We studied the effect of PHE volume expansion in the first 72 hours (iPHE) and its relationship w...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.115.010054
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Patient selection is crucial in the endovascular treatment of acute ischemic stroke patients. Baseline computed tomographic (CT) images, evaluated with the Alberta Stroke Program Early CT Scale (ASPECTS), are considered significant predictors of outcome. In this study, we evaluated CT images and ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.001068
更新日期:2013-08-01 00:00:00
abstract::Arteriolar diameters and venular erythrocyte velocities in the small pial vessels on the surface of the cat brain were measured by TV methods during induced epileptic seizures through a cranial window. Grand mal seizures maximally dilated arterioles and increased venular erythrocyte velocity up to 400%. High positive ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.7.1.83
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Cardiac involvement in Whipple's disease is not an uncommon phenomenon in autopsies, but its clinical occurrence is often overshadowed by gastrointestinal symptoms. We report a very atypical manifestation of this disorder. SUMMARY OF REPORT:An extraordinary presentation of an extremely long-lasting, culture...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.31.8.2002
更新日期:2000-08-01 00:00:00
abstract::Brain injury, including ischemia, changes normal astrocytes into reactive species that hypertrophy and begin to proliferate. Understanding the mechanisms that underlie these changes could lead to new abilities to promote regeneration and retard neural degeneration after ischemia. Because ionic changes occur after nonn...
journal_title:Stroke
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We previously reported increased incidence of ischemic stroke among both blacks and whites with diabetes mellitus, especially in those aged <55 years. With rising prevalence of diabetes mellitus in the past decade, we revisit the impact of diabetes mellitus on stroke incidence in the same populat...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.113.001318
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Carotid artery intima-media thickness (IMT) is a marker of cardiovascular disease associated with incident stroke. We studied whether IMT rate of change is associated with stroke. METHODS:We studied 5028 participants of the Multi-Ethnic Study of Atherosclerosis (MESA) comprising white, Chinese, ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.625186
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Transtemporal insonation in transcranial Doppler sonography is often impaired by an insufficient signal-to-noise ratio, especially in elderly patients. A transpulmonary stable air microbubble suspension was injected intravenously in humans as an intracranial ultrasonic contrast agent. METHODS:In...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.24.12.1903
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There have not been any new epidemiological studies related to stroke in Tibet for 20 years. This study aimed to collect stroke data from The City Staff Medical Insurance Registry in Lhasa, Tibet, to describe the incidence, clinical subtypes, and associated risk factors of stroke. METHODS:We use...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.586669
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Some clinical models, like California ABCD and unified ABCD2 scores, are now available to predict the early risk of stroke after a TIA. Despite the transitivity of symptoms, DWI identified an area of acute brain ischemia in almost half of patients. It would be interesting to know how the presence...
journal_title:Stroke
pub_type: 信件
doi:10.1161/STROKEAHA.108.537969
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke is the leading cause of disability in the Western world; however, few therapies are at hand to decrease this burden. SUMMARY OF REVIEW:Endothelial progenitor cells (EPCs) have been introduced in cardiovascular medicine as factotums. EPCs can repair damaged endothelium and attenuate the de...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.507251
更新日期:2008-07-01 00:00:00