Overexpression of CuZn-SOD prevents lipopolysaccharide-induced endothelial dysfunction.

abstract：BACKGROUND AND PURPOSE:In animals, drugs that increase brain amine concentrations influence the rate and degree of recovery from cortical lesions. It is therefore conceivable that antidepressants may influence outcome after ischemic brain injury in humans. We evaluated the effects of the norepinephrine reuptake blocker...

journal_title：Stroke

authors： Dam M,Tonin P,De Boni A,Pizzolato G,Casson S,Ermani M,Freo U,Piron L,Battistin L

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional neuroimaging studies have demonstrated right inferior frontal gyrus (IFG) activation in poststroke aphasia. It remains unclear whether this activation is essential for language performance. We tested this hypothesis in a positron emission tomography (PET) activation study during a sema...

journal_title：Stroke

authors： Winhuisen L,Thiel A,Schumacher B,Kessler J,Rudolf J,Haupt WF,Heiss WD

更新日期：2005-08-01 00:00:00

abstract：:One hundred and sixteen carotid artery bruits were assessed using quantitative phonoangiography (spectral bruit analysis - SBA). This technique uses the averaged break frequency of the bruit to calculate the diameter of he residual lumen at the site of stenosis. Biplanar contrast arteriography was performed on 43 (37%...

journal_title：Stroke

authors： Knox R,Breslau P,Strandness DE Jr

更新日期：1981-11-01 00:00:00

abstract：:Background and Purpose- Knowledge of the use of secondary preventive medication in young adults is limited. We studied the use of statins and its association with subsequent vascular events in young adults with ischemic stroke-a patient group with a known low burden of atherosclerosis. Methods- The study population in...

journal_title：Stroke

authors： van Dongen MME,Aarnio K,Martinez-Majander N,Pirinen J,Sinisalo J,Lehto M,Kaste M,Tatlisumak T,de Leeuw FE,Putaala J

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Maternal cigarette smoking increases the risk of neonatal morbidity. We tested the hypothesis that perinatal nicotine exposure causes heightened brain vulnerability to hypoxic-ischemic (HI) injury in neonatal rats through aberrant expression patterns of angiotensin II type 1 (AT(1)R) and type 2 (...

journal_title：Stroke

authors： Li Y,Xiao D,Dasgupta C,Xiong F,Tong W,Yang S,Zhang L

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The first goal of this study was to determine the effect of glutamate on permeability and reactivity of the cerebral microcirculation. The second goal of this study was to determine a possible role for nitric oxide in the effects of glutamate on the cerebral microcirculation. METHODS:We examined...

journal_title：Stroke

authors： Mayhan WG,Didion SP

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to investigate the periprocedural morbidity, mortality, and long-term clinical and angiographic follow-up using stent-assisted coiling and stenting alone for treatment of cranial fusiform dissecting and atherosclerotic aneurysms. METHODS:The Institutional Review Boa...

journal_title：Stroke

authors： Wakhloo AK,Mandell J,Gounis MJ,Brooks C,Linfante I,Winer J,Weaver JP

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We tested the hypothesis that sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, promotes functional recovery and neurogenesis after stroke. METHODS:Male Wistar rats were subjected to embolic middle cerebral artery occlusion. Sildenafil (Viagra) was administered orally for 7 consecutive da...

journal_title：Stroke

authors： Zhang R,Wang Y,Zhang L,Zhang Z,Tsang W,Lu M,Zhang L,Chopp M

更新日期：2002-11-01 00:00:00

abstract：:We have evaluated carotid gamma imaging using 111Indium-labelled platelets in the diagnosis of carotid artery disease and measured the accumulation of labelled platelets on endarterectomy specimens. Autologous 111In labelled platelets were injected in 25 patients with TIA. Gamma images were then taken daily and indepe...

journal_title：Stroke

authors： Goldman M,Leung JO,Aukland A,Hawker RJ,Drolc Z,McCollum CN

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Randomized clinical trials testing aspirin in relatively low-risk, middle-aged people have consistently shown small increases in stroke associated with aspirin use. We analyzed the relationship between the regular use of aspirin and incident ischemic and hemorrhagic stroke among people aged 65 ye...

journal_title：Stroke

authors： Kronmal RA,Hart RG,Manolio TA,Talbert RL,Beauchamp NJ,Newman A

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains unknown whether the effects of 0.6 mg/kg alteplase differ with occlusion site of the middle cerebral artery (MCA). We therefore evaluated the effects of 0.6 mg/kg intravenous alteplase in patients with different sites of MCA occlusion. METHODS:An exploratory analysis was made of 57 pa...

journal_title：Stroke

authors： Hirano T,Sasaki M,Mori E,Minematsu K,Nakagawara J,Yamaguchi T,Japan Alteplase Clinical Trial II Group.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hypertension control is a cornerstone of preventive treatment in patients at risk for cerebral attack. The aim of this study was to analyze hypertension management in secondary prevention of stroke as compared with patients in secondary prevention of myocardial infarction (MI). METHODS:The ECLAT...

journal_title：Stroke

authors： Amar J,Cambou JP,Touzé E,Bongard V,Jullien G,Vahanian A,Coppé G,Mas JL,ECLAT1 Study Investigators.

更新日期：2004-07-01 00:00:00

abstract：:Cerebrovascular ring-like fat deposition, which was noted only in hypertensive rats but never observed in normotensive rats even after they had been fed a high-fat cholesterol (HFC) diet for a long time, was successfully developed in the posterior communicating or other cerebrobasal arteries in normotensive rats fed a...

journal_title：Stroke

authors： Yamori Y,Horie R,Sato M,Fukase M

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study aims to investigate the association between insulin resistance (IR) and silent lacunar infarction (SLI) in healthy adults. METHODS:We recruited 2326 healthy Korean adults who took health checkups, including a brain magnetic resonance imaging. SLI was defined as an infarction measuring...

journal_title：Stroke

authors： Lee JE,Shin DW,Yun JM,Kim SH,Nam YS,Cho B,Lim JS,Jeong HY,Kwon HM,Park JH

更新日期：2016-12-01 00:00:00

abstract：:Survival and recurrences after stroke were assessed prospectively in a general population sample of 5184 subjects followed biennially for 26 years. Initial strokes occurred in 198 men and 196 women. There were 84 second and 27 third strokes and 223 deaths reported. Thirty day case-fatality rates for initial strokes we...

journal_title：Stroke

authors： Sacco RL,Wolf PA,Kannel WB,McNamara PM

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence of a relationship of fish intake to stroke incidence or mortality is weak. This report examines the association of fish consumption with stroke. METHODS:A cohort of 2107 men aged 40 to 55 years from the Chicago Western Electric Study who were free of coronary heart disease and stroke th...

journal_title：Stroke

authors： Orencia AJ,Daviglus ML,Dyer AR,Shekelle RB,Stamler J

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:High-sensitivity C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) are hypothesized to be biomarkers of systemic inflammation and risk of myocardial infarction (MI) and stroke. Little is known, however, about the stability of these markers over time, and in particul...

journal_title：Stroke

authors： Elkind MS,Leon V,Moon YP,Paik MC,Sacco RL

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several studies have found a morning peak in onset of stroke. A similar peak has been suggested for subarachnoid hemorrhage (SAH), which seems in contradiction with the physical activities associated with aneurysmal rupture. Most studies included only a few patients with SAH. We analyzed time of ...

journal_title：Stroke

authors： Vermeer SE,Rinkel GJ,Algra A

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in the elderly. We undertook an international survey to characterize the frequency of AF-associated stroke, methods of AF detection, and patient features. METHODS:Consecutive patie...

journal_title：Stroke

authors： Perera KS,Vanassche T,Bosch J,Swaminathan B,Mundl H,Giruparajah M,Barboza MA,O'Donnell MJ,Gomez-Schneider M,Hankey GJ,Yoon BW,Roxas A Jr,Lavallee P,Sargento-Freitas J,Shamalov N,Brouns R,Gagliardi RJ,Kasner SE,Pieroni

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Copeptin has been associated with recurrent cerebrovascular events after transient ischemic attack (TIA). In an independent cohort, we evaluated copeptin for the prediction of recurrent cerebrovascular events within 3 months after TIA and assessed the incremental value of copeptin compared with t...

journal_title：Stroke

authors： De Marchis GM,Weck A,Audebert H,Benik S,Foerch C,Buhl D,Schuetz P,Jung S,Seiler M,Morgenthaler NG,Mattle HP,Mueller B,Christ-Crain M,Arnold M,Katan M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The efficacy and safety of the selective serotonin reuptake inhibitor fluoxetine have rarely been studied in the treatment of poststroke emotional disturbances. METHODS:Stroke patients (152) who had poststroke depression (PSD), emotional incontinence (PSEI), or anger proneness (PSAP) were studie...

journal_title：Stroke

authors： Choi-Kwon S,Han SW,Kwon SU,Kang DW,Choi JM,Kim JS

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acetazolamide is commonly used with single-photon CT to assess the cerebrovascular reserve in patients with internal carotid artery stenosis or occlusion. In this study we wanted to evaluate the effects of adenosine, a well-known vasodilatatory compound with a short biological half-life, on brain...

journal_title：Stroke

authors： Soricelli A,Postiglione A,Cuocolo A,De Chiara S,Ruocco A,Brunetti A,Salvatore M,Ell PJ

更新日期：1995-09-01 00:00:00

abstract：:Background and Purpose- Timely access to endovascular thrombectomy (EVT) centers is vital for best acute ischemic stroke outcomes. Methods- US stroke-treating centers were mapped utilizing geo-mapping and stratified into non-EVT or EVT if they reported ≥1 acute ischemic stroke thrombectomy code in 2017 to Center for M...

journal_title：Stroke

authors： Sarraj A,Savitz S,Pujara D,Kamal H,Carroll K,Shaker F,Reddy S,Parsha K,Fournier LE,Jones EM,Sharrief A,Martin-Schild S,Grotta J

更新日期：2020-04-01 00:00:00

abstract：:It remains uncertain whether platelet activation in ischemic stroke is contributory or secondary to brain ischemia. The efficacy of aspirin (ASA) in stroke prevention suggests that platelet activation contributes to the occurrence of stroke. On the other hand, platelet activation may be simply a generalized consequenc...

journal_title：Stroke

authors： Shah AB,Beamer N,Coull BM

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perioperative strokes (POS) are rare but serious complications for which mechanical thrombectomy could be beneficial. We aimed to compare the technical results and patients outcomes in a population of POS versus non-POS (nPOS) treated by mechanical thrombectomy. METHODS:From 2010 to 2017, 25 pat...

journal_title：Stroke

authors： Premat K,Clovet O,Frasca Polara G,Shotar E,Bartolini B,Yger M,Di Maria F,Baronnet F,Pistocchi S,Le Bouc R,Pires C,Sourour N,Alamowitch S,Samson Y,Degos V,Clarençon F

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several observations indicate that, during energy deprivation, endogenous dopamine may become neurotoxic. Accordingly, the nucleus striatum is a preferential site of silent infarcts in humans, and experimental ischemia caused by homolateral carotid occlusion selectively damages this dopamine-enri...

journal_title：Stroke

authors： Saulle E,Centonze D,Martín AB,Moratalla R,Bernardi G,Calabresi P

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We found age-related vulnerability to cerebral ischemia in the hippocampus and striatum in spontaneously hypertensive rats. Further study revealed that ischemia-induced release of hippocampal taurine, an inhibitory amino acid, was reduced by 40% in aged rats compared with adult rats, which sugges...

journal_title：Stroke

authors： Yao H,Ooboshi H,Ibayashi S,Uchimura H,Fujishima M

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preceding infection as an important risk factor for ischemic stroke has been reported but neglected for hemorrhagic stroke, especially in young and middle-aged patients. This study investigates whether newly diagnosed leptospirosis is associated with an increased risk of stroke. METHODS:We ident...

journal_title：Stroke

authors： Li KY,Chou MC,Wei JC,Lin MC,Hung YM,Chang R

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to describe the frequency and characteristics of acute ischemic stroke and transient ischemic attacks presenting predominantly with amnesia (ischemic amnesia) and to identify clinical clues for differentiating them from transient global amnesia (TGA). METHODS:We retrospectively analyzed...

journal_title：Stroke

authors： Michel P,Beaud V,Eskandari A,Maeder P,Demonet JF,Eskioglou E

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perfusion-weighted magnetic resonance imaging (PWI) is a reliable and semiquantitative method for estimating cerebral hemodynamics. We sought to evaluate the potential of PWI for assessing cerebral blood flow (CBF) and metabolism compared with positron emission tomography (PET) in patients with c...

journal_title：Stroke

authors： Kajimoto K,Moriwaki H,Yamada N,Hayashida K,Kobayashi J,Miyashita K,Naritomi H

更新日期：2003-07-01 00:00:00