Exaggeration of focal cerebral ischemia in transgenic mice carrying human Renin and human angiotensinogen genes.

abstract：BACKGROUND AND PURPOSE:Computed tomography is now routinely used in many hospitals to investigate cerebrovascular disease. The purpose of our prospective study was to determine whether cranial computed tomography in connection with neurological assessment was useful in prognostic evaluation of survival after acute stro...

journal_title：Stroke

authors： Rasmussen D,Køhler O,Worm-Petersen S,Blegvad N,Jacobsen HL,Bergmann I,Egeblad M,Friis M,Nielsen NT

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebrovascular disease can complicate head and neck radiotherapy and result in transient ischemic attack and ischemic stroke. Although the incidence of radiation vasculopathy is predicted to rise with improvements in median cancer survival, the pathogenesis, natural history, and management of th...

journal_title：Stroke

authors： Plummer C,Henderson RD,O'Sullivan JD,Read SJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Epidemiological data about stroke are scarce in low- and middle-income Latin-American countries. We investigated annual incidence of first-ever stroke and transient ischemic attack (TIA) and 30-day case-fatality rates in a population-based setting in Tandil, Argentina. METHODS:We prospectively i...

journal_title：Stroke

authors： Bahit MC,Coppola ML,Riccio PM,Cipriano LE,Roth GA,Lopes RD,Feigin VL,Borrego Guerrero B,De Martino M,Díaz A,Ferrante D,Funaro F,Lavados P,Lewin ML,López DH,Macarrone P,Marciello R,Marino D,Martens C,Martínez P,Odr

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The method described provides a rational means for determining whether to institute chronic anticoagulation to prevent stroke in patients with chronic atrial fibrillation under a variety of clinical circumstances. SUMMARY OF COMMENT:The concept of expected value is used in conjunction with data from clinica...

journal_title：Stroke

authors： Nadeau SE

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ageing is associated with a decline in cerebral blood flow. Animal studies have shown that cholesterol-lowering therapy with statins might preserve cerebral blood flow (CBF). We examined the effect of 40 mg pravastatin on the decline in CBF and brain volume in a subset of elderly subjects partici...

journal_title：Stroke

authors： ten Dam VH,Box FM,de Craen AJ,van den Heuvel DM,Bollen EL,Murray HM,van Buchem MA,Westendorp RG,Blauw GJ,PROSPER Study Group.

更新日期：2005-08-01 00:00:00

abstract：:Reduction in cerebral blood flow (CBF) following global ischemia has been implicated as a pathogenetic mechanism in progressive brain damage seen after restoration of effective cardiac action and cerebral perfusion pressure. There are serious limitations to many of the techniques for measuring regional cerebral blood ...

journal_title：Stroke

authors： Jackson DL,Dole WP,McGloin J,Rosenblatt JI

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite rapid advancements in intracranial aneurysm management, there is no evidence as of yet that this has translated into improvement in overall prognosis. METHODS:We compared 2 periods of aneurysm management, 1998 to 2003 (n=1023 aneurysms) and 2007 to 2013 (n=1499 aneurysms), at a single, h...

journal_title：Stroke

authors： Chua MH,Griessenauer CJ,Stapleton CJ,He L,Thomas AJ,Ogilvy CS

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A previous systematic review of randomized trials suggested a positive effect of antiplatelet therapy in patients with aneurysmal subarachnoid hemorrhage (SAH). We performed a randomized controlled trial to assess whether acetylsalicylic acid (ASA) reduces the risk of delayed ischemic neurologica...

journal_title：Stroke

authors： van den Bergh WM,MASH Study Group.,Algra A,Dorhout Mees SM,van Kooten F,Dirven CM,van Gijn J,Vermeulen M,Rinkel GJ

更新日期：2006-09-01 00:00:00

abstract：:A xenon-133 method was used to measure cerebral blood flow (CBF) before and after cerebrospinal fluid (CSF) removal in patients with normal pressure hydrocephalus (NPH). Preliminary results suggested that shunting should be performed on patients whose CBF increased after CSF removal. There was a significant increase i...

journal_title：Stroke

authors： Mamo HL,Meric PC,Ponsin JC,Rey AC,Luft AG,Seylaz JA

更新日期：1987-11-01 00:00:00

abstract：:The Stenting and Aggressive Medical Management for Preventing Recurrent Stroke and Intracranial Stenosis (SAMMPRIS) trial, a randomized clinical trial comparing aggressive medical management to stenting with aggressive medical management for symptomatic intracranial stenosis, was prematurely halted when a high rate of...

journal_title：Stroke

authors： Marks MP

更新日期：2012-02-01 00:00:00

abstract：:Background and Purpose- Besides the established spot sign (SS) in computed tomography angiography (CTA), there is growing evidence that different imaging markers in noncontrast CT offer great value for outcome prediction in patients with intracerebral hemorrhage (ICH). However, it is unclear how the concurrent presenc...

journal_title：Stroke

authors： Sporns PB,Kemmling A,Schwake M,Minnerup J,Nawabi J,Broocks G,Wildgruber M,Fiehler J,Heindel W,Hanning U

更新日期：2018-10-01 00:00:00

abstract：:Patients with chronic aphasia were assigned randomly to a group to receive either conventional aphasia therapy or constraint-induced (CI) aphasia therapy, a new therapeutic technique requiring intense practice over a relatively short period of consecutive days. CI aphasia therapy is realized in a communicative therape...

journal_title：Stroke

authors： Pulvermüller F,Neininger B,Elbert T,Mohr B,Rockstroh B,Koebbel P,Taub E

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:the Penumbra Pivotal Stroke Trial reported a 25% good outcome (modified Rankin scale score ≤ 2) despite an 81% recanalization rate. We evaluated the association of a favorable initial noncontrast CT and a short time to recanalization in predicting good outcome. METHODS:data were from the Penumbr...

journal_title：Stroke

authors： Goyal M,Menon BK,Coutts SB,Hill MD,Demchuk AM,Penumbra Pivotal Stroke Trial Investigators, Calgary Stroke Program, and the Seaman MR Research Center.

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to evaluate the diagnostic accuracy of ultrasound criteria for recanalization during real-time transcranial Doppler monitoring of intra-arterial reperfusion procedures in acute ischemic stroke patients in an international, multicenter study. METHODS:Consecutive acute ischemic stroke pa...

journal_title：Stroke

authors： Tsivgoulis G,Ribo M,Rubiera M,Vasdekis SN,Barlinn K,Athanasiadis D,Bavarsad Shahripour R,Giannopoulos S,Stamboulis E,Harrigan MR,Molina CA,Alexandrov AV

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study investigated the influence of the antiplatelet agent acetylsalicylic acid (ASA) on cerebral microembolism as detected by transcranial Doppler sonography (TCD). METHODS:Nine patients with recent transient ischemic attack or minor stroke of arterial origin were investigated. Eigh...

journal_title：Stroke

authors： Goertler M,Baeumer M,Kross R,Blaser T,Lutze G,Jost S,Wallesch CW

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recombinant tissue plasminogen activator (rtPA; Actilyse) is not as widely used in clinical practice as it could be. Have new data since 1995 strengthened the evidence sufficiently to justify more widespread use of rtPA? METHODS:We performed a sequential year-to-year cumulative meta-analysis of ...

journal_title：Stroke

authors： Wardlaw JM,Sandercock PA,Berge E

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The bedside clinical assessment of the patient with suspected stroke has not been well studied. Improving clinical skills may accelerate patient progress through the emergency department. We aimed to determine the frequency and nature of stroke mimics and to identify the key clinical features tha...

journal_title：Stroke

authors： Hand PJ,Kwan J,Lindley RI,Dennis MS,Wardlaw JM

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Neutrophil Extracellular Traps (NETs) are DNA extracellular networks decorated with histones and granular proteins produced by activated neutrophils. NETs have been identified as major triggers and structural factors of thrombosis. A recent study designated extracellular DNA threads from NETs as ...

journal_title：Stroke

authors： Ducroux C,Di Meglio L,Loyau S,Delbosc S,Boisseau W,Deschildre C,Ben Maacha M,Blanc R,Redjem H,Ciccio G,Smajda S,Fahed R,Michel JB,Piotin M,Salomon L,Mazighi M,Ho-Tin-Noe B,Desilles JP

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The apparent diffusion coefficient (ADC) of water should be sensitive to the cytotoxic edema triggered by energy failure during ischemia. Elevated values of T2. the nuclear MR transverse relaxation time of water, seen on T2 nuclear MR images detect vasogenic edema and infarcted areas. The tempora...

journal_title：Stroke

authors： Loubinoux I,Volk A,Borredon J,Guirimand S,Tiffon B,Seylaz J,Méric P

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Effects of anoxic stress on cerebrovascular responses to calcitonin gene-related peptide (CGRP) have not been examined previously. We determined the effects of total global ischemia on cerebral arteriolar responses to CGRP in newborn pigs. METHODS:Piglets were anesthetized and ventilated with a ...

journal_title：Stroke

authors： Louis TM,Meng W,Bari F,Errico RA,Busija DW

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cysteine could potentially lower the risk of stroke through antihypertensive and antioxidant effects. Our aim was to evaluate the hypothesis that cysteine intake is inversely associated with stroke incidence. METHODS:We used data from the Swedish Mammography Cohort, a population-based prospectiv...

journal_title：Stroke

authors： Larsson SC,Håkansson N,Wolk A

更新日期：2015-04-01 00:00:00

abstract：:Longitudinal stretch of the rabbit basilar artery produces local injury followed by prolonged circular constriction. After stretching and rapid release in vitro localized constrictions promptly occurred. This could be prevented by prior treatment with cyanide or calcium-free solution. Once produced, constrictions pers...

journal_title：Stroke

authors： Duckles SP,Bevan RD,Bevan JA

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:An increase in intima-media thickness (IMT) in the common carotid artery (CCA) is commonly used as a marker of atherosclerosis. The purpose of this study was to investigate the relationship between IMT in the CCA and atherosclerosis in the carotid bifurcation. METHODS:182 consecutive patients (m...

journal_title：Stroke

authors： Rosfors S,Hallerstam S,Jensen-Urstad K,Zetterling M,Carlström C

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autonomic nervous system diseases affect systemic blood pressure regulation. Patients with autonomic nervous system diseases have consistently larger drops in blood pressure associated with standing than the normal population. Autonomic dysfunction and/or these changes in blood pressure may affec...

journal_title：Stroke

authors： Blaber AP,Bondar RL,Stein F,Dunphy PT,Moradshahi P,Kassam MS,Freeman R

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little is known about how regions vary in their use of thrombolysis (intravenous tissue-type plasminogen activator and intra-arterial treatment) for acute stroke. We sought to determine regional variation in thrombolysis treatment and investigate the extent to which regional variation is accounte...

journal_title：Stroke

authors： Skolarus LE,Meurer WJ,Shanmugasundaram K,Adelman EE,Scott PA,Burke JF

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to assess the prevalence of extracranial carotid artery atherosclerosis and its relation to principal cardiovascular risk factors at different ages in a sample of the general population. METHODS:B-mode ultrasonography was used to investigate the carotid district in 457 ...

journal_title：Stroke

authors： Fabris F,Zanocchi M,Bo M,Fonte G,Poli L,Bergoglio I,Ferrario E,Pernigotti L

更新日期：1994-06-01 00:00:00

abstract：:Eighty-one young Japanese patients with occlusive thromboaortopathy (Takayasu's disease) were classed into three groups according to the degree and extent of diameter stenosis in the 4 cervical arterial systems, as determined by serial aortography. Class I was made up of 63 patients with 70% or greater stenosis in les...

journal_title：Stroke

authors： Ishikawa K,Uyama M,Asayama K

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticoagulation is a highly effective secondary prevention in patients with cardioembolic stroke and atrial fibrillation/flutter (AF). However, the condition remains underdiagnosed, because paroxysmal AF may be missed by diagnostic tests in the acute phase. In this study, the sensitivity of AF de...

journal_title：Stroke

authors： Kallmünzer B,Breuer L,Hering C,Raaz-Schrauder D,Kollmar R,Huttner HB,Schwab S,Köhrmann M

更新日期：2012-04-01 00:00:00

abstract：:We have evaluated carotid gamma imaging using 111Indium-labelled platelets in the diagnosis of carotid artery disease and measured the accumulation of labelled platelets on endarterectomy specimens. Autologous 111In labelled platelets were injected in 25 patients with TIA. Gamma images were then taken daily and indepe...

journal_title：Stroke

authors： Goldman M,Leung JO,Aukland A,Hawker RJ,Drolc Z,McCollum CN

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Kawasaki disease is a febrile disease of children notable for systemic vasculitis. There have been many previous reports of various complications, including disorders of the central nervous system. We evaluated cerebral perfusion during the acute stage in patients with Kawasaki disease. METHODS:...

journal_title：Stroke

authors： Ichiyama T,Nishikawa M,Hayashi T,Koga M,Tashiro N,Furukawa S

更新日期：1998-07-01 00:00:00