Cerebral blood flow in normal pressure hydrocephalus.

Abstract:

:A xenon-133 method was used to measure cerebral blood flow (CBF) before and after cerebrospinal fluid (CSF) removal in patients with normal pressure hydrocephalus (NPH). Preliminary results suggested that shunting should be performed on patients whose CBF increased after CSF removal. There was a significant increase in CBF in patients with NPH, which was confirmed by the favorable outcome of 88% of patients shunted. The majority of patients with senile and presenile dementia showed a decrease or no change in CBF after CSF removal. It is suggested that although changes in CBF and clinical symptoms of NPH may have the same cause, i.e., changes in the cerebral intraparenchymal pressure, there is no simple direct relation between these two events. The mechanism underlying the loss of autoregulation observed in NPH is also discussed.

journal_name

Stroke

journal_title

Stroke

authors

Mamo HL,Meric PC,Ponsin JC,Rey AC,Luft AG,Seylaz JA

doi

10.1161/01.str.18.6.1074

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

1074-80

issue

6

eissn

0039-2499

issn

1524-4628

journal_volume

18

pub_type

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