Abstract:
:A xenon-133 method was used to measure cerebral blood flow (CBF) before and after cerebrospinal fluid (CSF) removal in patients with normal pressure hydrocephalus (NPH). Preliminary results suggested that shunting should be performed on patients whose CBF increased after CSF removal. There was a significant increase in CBF in patients with NPH, which was confirmed by the favorable outcome of 88% of patients shunted. The majority of patients with senile and presenile dementia showed a decrease or no change in CBF after CSF removal. It is suggested that although changes in CBF and clinical symptoms of NPH may have the same cause, i.e., changes in the cerebral intraparenchymal pressure, there is no simple direct relation between these two events. The mechanism underlying the loss of autoregulation observed in NPH is also discussed.
journal_name
Strokejournal_title
Strokeauthors
Mamo HL,Meric PC,Ponsin JC,Rey AC,Luft AG,Seylaz JAdoi
10.1161/01.str.18.6.1074subject
Has Abstractpub_date
1987-11-01 00:00:00pages
1074-80issue
6eissn
0039-2499issn
1524-4628journal_volume
18pub_type
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