Blood use in cerebrovascular neurosurgery.

abstract：BACKGROUND AND PURPOSE:Astrocytes are potent regulators of brain capillary endothelial cell function. Recently, astrocytes were shown to regulate brain capillary endothelial expression of the fibrinolytic enzyme tissue plasminogen activator (tPA) and the anticoagulant thrombomodulin (TM). To study the mechanism of this...

journal_title：Stroke

authors： Tran ND,Correale J,Schreiber SS,Fisher M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Three-dimensional pseudocontinuous arterial spin labeling with multiple postlabeling delays has been used to assess cerebral blood flow (CBF). We used this modality to estimate antegrade and collateral flow in patients with unilateral middle cerebral artery stenosis. METHODS:Consecutive patients...

journal_title：Stroke

authors： Lyu J,Ma N,Liebeskind DS,Wang DJ,Ma L,Xu Y,Wang T,Miao Z,Lou X

更新日期：2016-02-01 00:00:00

abstract：:Using the dexamethasone suppression test, we studied the activity of the hypothalamic-pituitary-adrenal axis within the first week after onset in 62 patients with acute ischemic stroke. Compared with two control groups (one comprising 25 elderly patients with various acute medical disorders and the other comprising 33...

journal_title：Stroke

authors： Olsson T,Aström M,Eriksson S,Forssell A

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hypothermia improves outcome in resuscitated patients and newborns with hypoxic brain injury. We studied the safety and feasibility of mild hypothermia in awake patients with stroke after intravenous thrombolysis. METHODS:Patients were randomized 1:1 to mild hypothermia (35°C) or to standard str...

journal_title：Stroke

authors： Piironen K,Tiainen M,Mustanoja S,Kaukonen KM,Meretoja A,Tatlisumak T,Kaste M

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data on long-term outcome after intravenous tissue-type plasminogen activator (tPA) in ischemic stroke are limited. We examined the risk of long-term mortality, recurrent ischemic stroke, and major bleeding, including intracranial and gastrointestinal bleeding, in intravenous tPA-treated patients...

journal_title：Stroke

authors： Schmitz ML,Simonsen CZ,Hundborg H,Christensen H,Ellemann K,Geisler K,Iversen H,Madsen C,Rasmussen MJ,Vestergaard K,Andersen G,Johnsen SP

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The cerebrovascular contribution to ischemic preconditioning (IPC) has been scarcely explored. Using in vivo and in vitro approaches, we investigated the involvement of the blood-brain barrier and the role of its cellular components. METHODS:Seven-minute occlusion of the right middle cerebral ar...

journal_title：Stroke

authors： Gesuete R,Orsini F,Zanier ER,Albani D,Deli MA,Bazzoni G,De Simoni MG

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preceding infection as an important risk factor for ischemic stroke has been reported but neglected for hemorrhagic stroke, especially in young and middle-aged patients. This study investigates whether newly diagnosed leptospirosis is associated with an increased risk of stroke. METHODS:We ident...

journal_title：Stroke

authors： Li KY,Chou MC,Wei JC,Lin MC,Hung YM,Chang R

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND AND PURPOSE:Central nervous system serotonergic neurotransmission appears to play a role in mood disorders, eating habits, and sleep, and also modulates blood pressure and metabolism. This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis...

journal_title：Stroke

authors： Muldoon MF,Mackey RH,Sutton-Tyrrell K,Flory JD,Pollock BG,Manuck SB

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Most randomized controlled trials of venous thromboembolism prophylaxis have focused on reduction of deep vein thrombosis, predominantly asymptomatic deep vein thrombosis, detected on imaging. We aimed to estimate the effects of graduated compression stockings on venous thromboembolism events, su...

journal_title：Stroke

authors： CLOTS Trials Collaboration.,Dennis M,Sandercock P,Reid J,Graham C,Murray G,Venables G,Rudd A,Bowler G

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Numerous studies have demonstrated higher stroke mortality rates in adults residing in the Southeastern United States (the "Stroke Belt"). If the Stroke Belt is solely caused by regional differences in atherosclerotic stroke risk factors, it should not apply to children. METHODS:For the years 19...

journal_title：Stroke

authors： Fullerton HJ,Elkins JS,Johnston SC

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:the Penumbra Pivotal Stroke Trial reported a 25% good outcome (modified Rankin scale score ≤ 2) despite an 81% recanalization rate. We evaluated the association of a favorable initial noncontrast CT and a short time to recanalization in predicting good outcome. METHODS:data were from the Penumbr...

journal_title：Stroke

authors： Goyal M,Menon BK,Coutts SB,Hill MD,Demchuk AM,Penumbra Pivotal Stroke Trial Investigators, Calgary Stroke Program, and the Seaman MR Research Center.

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the resting regional cerebral blood flow (rCBF) in aphasic patients has been thoroughly investigated with positron emission tomography (PET) and single-photon emission CT, and PET studies in normal subjects have elucidated the functional localization of language processing, little is kno...

journal_title：Stroke

authors： Ohyama M,Senda M,Kitamura S,Ishii K,Mishina M,Terashi A

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In acute ischemic stroke, fast and complete recanalization of the occluded vessel is associated with improved outcomes. We describe a novel measure for newer generation devices: the first pass effect (FPE). FPE is defined as achieving a complete recanalization with a single thrombectomy device pa...

journal_title：Stroke

authors： Zaidat OO,Castonguay AC,Linfante I,Gupta R,Martin CO,Holloway WE,Mueller-Kronast N,English JD,Dabus G,Malisch TW,Marden FA,Bozorgchami H,Xavier A,Rai AT,Froehler MT,Badruddin A,Nguyen TN,Taqi MA,Abraham MG,Yoo AJ,

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:One hundred twelve patients undergoing elective carotid endarterectomy for symptomatic and asymptomatic carotid artery stenosis were enrolled in a prospective study to evaluate the incidence of change in postoperative cerebral function. METHODS:Patients were evaluated preoperatively and postoper...

journal_title：Stroke

authors： Heyer EJ,Adams DC,Solomon RA,Todd GJ,Quest DO,McMahon DJ,Steneck SD,Choudhri TF,Connolly ES

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In an inner-London teaching hospital, a randomized trial of "conventional" care versus early discharge to community-based therapy found no significant differences in clinical outcomes between patient groups. This report examines the economic consequences of the alternative strategies. METHODS:On...

journal_title：Stroke

authors： Beech R,Rudd AG,Tilling K,Wolfe CD

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Toll-like receptors (TLRs) and the scavenger receptor CD36 are key molecular sensors for the innate immune response to invading pathogens. However, these receptors may also recognize endogenous "danger signals" generated during brain injury, such as cerebral ischemia, and trigger a maladaptive in...

journal_title：Stroke

authors： Abe T,Shimamura M,Jackman K,Kurinami H,Anrather J,Zhou P,Iadecola C

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial atherosclerosis is one of the main causes of stroke, and high-resolution magnetic resonance imaging provides useful imaging biomarkers related to the risk of ischemic events. This study aims to evaluate differences in histogram features between culprit and nonculprit intracranial ath...

journal_title：Stroke

authors： Shi Z,Li J,Zhao M,Peng W,Meddings Z,Jiang T,Liu Q,Teng Z,Lu J

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animal models of cerebral ischemia, matrix metalloproteinase (MMP) expression was significantly increased and related to blood-brain barrier disruption, edema formation, and hemorrhagic transformation (HT). MMP inhibitors reduce HT after embolic ischemia in tissue-type plasminogen activator-tr...

journal_title：Stroke

authors： Montaner J,Alvarez-Sabín J,Molina CA,Anglés A,Abilleira S,Arenillas J,Monasterio J

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dichloroacetate facilitates a decrease in brain lactate during reperfusion after incomplete ischemia. This study examined the possible activation of pyruvate dehydrogenase enzyme by dichloroacetate to explain this effect. Because the duration of ischemia and hyperglycemia exacerbate ischemic brai...

journal_title：Stroke

authors： Dimlich RV,Nielsen MM

更新日期：1992-08-01 00:00:00

abstract：:Background and Purpose- We aimed to compare outcomes of ischemic stroke patients with nonvalvular atrial fibrillation between earlier and later initiation of direct oral anticoagulants (DOACs) after stroke onset. Methods- From data for 1192 nonvalvular atrial fibrillation patients with acute ischemic stroke or transie...

journal_title：Stroke

authors： Mizoguchi T,Tanaka K,Toyoda K,Yoshimura S,Itabashi R,Takagi M,Todo K,Shiozawa M,Yagita Y,Yoshimoto T,Terasaki T,Yamagami H,Takizawa S,Inoue M,Kamiyama K,Ihara M,Okada Y,Kitazono T,Koga M,SAMURAI Study Investigators.

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The visual analogue scale is a self-reported, validated tool to measure quality of life (QoL). Our purpose was to determine whether baseline QoL predicted strokes in the ALLHAT study (Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial) and evaluate determinants of poststr...

journal_title：Stroke

authors： Shams T,Auchus AP,Oparil S,Wright CB,Wright J,Furlan AJ,Sila CA,Davis BR,Pressel S,Yamal JM,Einhorn PT,Lerner AJ,ALLHAT Collaborative Research Group.

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multicenter clinical trials attempt to select sites that can move rapidly to randomization and enroll sufficient numbers of patients. However, there are few assessments of the success of site selection. METHODS:In the CREST-2 (Carotid Revascularization and Medical Management for Asymptomatic Car...

journal_title：Stroke

authors： Demaerschalk BM,Brown RD Jr,Roubin GS,Howard VJ,Cesko E,Barrett KM,Longbottom ME,Voeks JH,Chaturvedi S,Brott TG,Lal BK,Meschia JF,Howard G,CREST-2 Investigators.

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multifocal signal loss lesions (MSLLs) on T2*-weighted gradient-echo (GE) MRI are believed to be microbleeds histopathologically. Previous epidemiological studies suggested that low serum cholesterol is associated with the increased risk of intracerebral hemorrhage. We investigated risk factors o...

journal_title：Stroke

authors： Lee SH,Bae HJ,Yoon BW,Kim H,Kim DE,Roh JK

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Inflammatory and immune mechanisms can precipitate cerebrovascular thrombosis and hemorrhage. Immunologic tolerance can be induced to a specific antigen by intranasal instillation of that antigen. Lymphocytes tolerized in this way provide local immunosuppression on restimulation with the same ant...

journal_title：Stroke

authors： Takeda H,Spatz M,Ruetzler C,McCarron R,Becker K,Hallenbeck J

更新日期：2002-09-01 00:00:00

abstract：:Visually apparent EEG changes associated with clamping the internal carotid artery appeared in 55 of 176 consecutive patients (31%) undergoing carotid endarterectomy without shunt. Attenuation of higher frequency activity was the most common change. Changes were moderate in 33 patients (19%) and major in 22 (12.5%). M...

journal_title：Stroke

authors： Blume WT,Ferguson GG,McNeill DK

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Persons with early stages of chronic kidney disease, defined by a decreased glomerular filtration rate (GFR), have an increased risk of cardiovascular disease. It is unclear whether decreased GFR is a risk factor for stroke. We assessed the association between GFR and stroke in a prospective popu...

journal_title：Stroke

authors： Bos MJ,Koudstaal PJ,Hofman A,Breteler MM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:National Institutes of Health Stroke Scale (NIHSS) item profiles that were recently proposed and validated may prove useful for clinical prognostication and research studies. We aimed to validate the NIHSS item profiles in hyper-acute stroke patients who received thrombolysis treatment (tissue-ty...

journal_title：Stroke

authors： Abdul-Rahim AH,Fulton RL,Sucharew H,Kleindorfer D,Khatri P,Broderick JP,Lees KR,SITS-MOST Steering Committee.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although left atrial enlargement (LAE) increases incident stroke risk, the association with recurrent stroke is less clear. Our aim was to determine the association of LAE with recurrent stroke most likely related to embolism (cryptogenic and cardioembolic) and all ischemic stroke recurrences. M...

journal_title：Stroke

authors： Yaghi S,Moon YP,Mora-McLaughlin C,Willey JZ,Cheung K,Di Tullio MR,Homma S,Kamel H,Sacco RL,Elkind MS

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To investigate whether neuroimaging information has added predictive value compared with clinical information for independency in activities of daily living (ADL) 1 year after stroke. METHODS:Seventy-five first-ever middle cerebral artery stroke survivors were evaluated in logistic regression an...

journal_title：Stroke

authors： Schiemanck SK,Kwakkel G,Post MW,Kappelle LJ,Prevo AJ

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few studies currently assess the health-related quality of life of individuals following a stroke. One of the major challenges of assessing quality of life is the high likelihood that after a stroke a patient will not be able to complete such an assessment. One practical solution is to have a fam...

journal_title：Stroke

authors： Mathias SD,Bates MM,Pasta DJ,Cisternas MG,Feeny D,Patrick DL

更新日期：1997-10-01 00:00:00