Reduction in distal emboli with proximal flow control during mechanical thrombectomy: a quantitative in vitro study.

abstract：BACKGROUND AND PURPOSE:Within different brain regions, we determine the comparative value of multiphase computed tomographic angiography (mCTA) and computed tomographic perfusion (CTP) in predicting follow-up infarction. METHODS:Patients with M1-middle cerebral artery occlusions were prospectively included in this mul...

journal_title：Stroke

authors： d'Esterre CD,Trivedi A,Pordeli P,Boesen M,Patil S,Hwan Ahn S,Najm M,Fainardi E,Shankar JJ,Rubiera M,Almekhlafi MA,Mandzia J,Khaw AV,Barber P,Coutts S,Hill MD,Demchuk AM,Sajobi T,Forkert ND,Goyal M,Lee TY,Menon B

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of our study was to characterize the patient profile and prognostic value associated with high positive IgG (>100 GPL) anticardiolipin antibodies (aCL). METHODS:We studied the clinical, laboratory, radiological, and prospective historical features of ischemic cerebrovascular disease in p...

journal_title：Stroke

authors： Verro P,Levine SR,Tietjen GE

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Venous thromboembolism and ischemic stroke are associated with unfavorable fibrin clot structure and function. We hypothesized that denser fibrin networks displaying impaired lysability characterize patients with cerebral venous sinus thrombosis (CVST). METHODS:We assessed plasma fibrin clot pro...

journal_title：Stroke

authors： Siudut J,Świat M,Undas A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke on board aircraft has been reported in retrospective case series, mainly focusing on economy class stroke syndrome. Data on the actual incidence, pathogenesis, and prognosis of stroke in commercial flights are lacking. METHODS:A prospective registry was designed to include all consecutive...

journal_title：Stroke

authors： Álvarez-Velasco R,Masjuan J,DeFelipe A,Corral I,Estévez-Fraga C,Crespo L,Alonso-Cánovas A

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke education, 1 of 8 endorsed stroke performance measures, consists of 5 specific subcomponents: risk factors, stroke warning signs, emergency medical service activation, physician follow-up, and discharge medications. We identified predictors of stroke education performance measure complianc...

journal_title：Stroke

authors： Nickles A,Fiedler J,Roberts S,Lyon-Callo S,Hurst R,Reeves M

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We describe the clinical, diagnostic, and outcome features of a cohort of white patients with idiopathic moyamoya disease treated in a German institution. METHODS:Our cohort included 21 white patients with moyamoya disease. Clinical and diagnostic features were obtained by retrospective chart re...

journal_title：Stroke

authors： Kraemer M,Heienbrok W,Berlit P

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In the US, blacks have a higher incidence of stroke and more severe strokes than whites. Our objective was to determine if differences in income, education, and insurance, as well as differences in the prevalence of stroke risk factors, accounted for the association between ethnicity and stroke. ...

journal_title：Stroke

authors： Bravata DM,Wells CK,Gulanski B,Kernan WN,Brass LM,Long J,Concato J

更新日期：2005-07-01 00:00:00

abstract：:Background and Purpose- Cerebral small vessel disease (cSVD) is the major vascular cause of cognitive decline and dementia. The pathogenesis of cSVD remains largely unknown, although several studies suggest a role for systemic inflammation. In certain pathophysiological situations, monocytes can reprogram toward a lon...

journal_title：Stroke

authors： Noz MP,Ter Telgte A,Wiegertjes K,Joosten LAB,Netea MG,de Leeuw FE,Riksen NP

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Copeptin has been associated with recurrent cerebrovascular events after transient ischemic attack (TIA). In an independent cohort, we evaluated copeptin for the prediction of recurrent cerebrovascular events within 3 months after TIA and assessed the incremental value of copeptin compared with t...

journal_title：Stroke

authors： De Marchis GM,Weck A,Audebert H,Benik S,Foerch C,Buhl D,Schuetz P,Jung S,Seiler M,Morgenthaler NG,Mattle HP,Mueller B,Christ-Crain M,Arnold M,Katan M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to evaluate the efficacy of remote ischemic conditioning (RIC) in patients with cerebral small-vessel disease. METHODS:Thirty patients with cerebral small-vessel disease-related mild cognitive impairment were enrolled in this prospective, randomized controlled study for 1 year. Besides ...

journal_title：Stroke

authors： Wang Y,Meng R,Song H,Liu G,Hua Y,Cui D,Zheng L,Feng W,Liebeskind DS,Fisher M,Ji X

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vascular effects of mental stress are only partially understood. Therefore, we studied effects of chronic stress and heart rate (HR) on endothelial function and cerebral ischemia. METHODS:129S6/SvEv mice were randomized to the I(f)-channel inhibitor ivabradine (10 mg/kg per day) or vehicle and u...

journal_title：Stroke

authors： Custodis F,Gertz K,Balkaya M,Prinz V,Mathar I,Stamm C,Kronenberg G,Kazakov A,Freichel M,Böhm M,Endres M,Laufs U

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelium-derived hyperpolarizing factor (EDHF)-mediated dilations are potentiated after several pathologies, including ischemia/reperfusion (I/R). However, no study to date has addressed the mechanism by which this potentiation occurs. This study tested the hypothesis that potentiated EDHF-med...

journal_title：Stroke

authors： Marrelli SP

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Astrocytes are potent regulators of brain capillary endothelial cell function. Recently, astrocytes were shown to regulate brain capillary endothelial expression of the fibrinolytic enzyme tissue plasminogen activator (tPA) and the anticoagulant thrombomodulin (TM). To study the mechanism of this...

journal_title：Stroke

authors： Tran ND,Correale J,Schreiber SS,Fisher M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional walk tests such as the 6- and 12-Minute Walk Test (ie, 6MWT and 12MWT, respectively) are submaximal measures used to determine functional capacity in individuals with compromised ability. The purpose of this study was to determine the relationship between these walk tests and measures ...

journal_title：Stroke

authors： Eng JJ,Chu KS,Dawson AS,Kim CM,Hepburn KE

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The goal of this study was to determine the alterations in contractile and dilatory responses and ultrastructure of the feline middle cerebral artery after hemorrhagic hypotension. METHODS:In the sodium pentobarbital anesthetized cats, a steady 50 mm Hg level of hypotension was reached by bleedi...

journal_title：Stroke

authors： Kovách AG,Szabó C,Faragó M,Lohinai Z,Fehér E

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains uncertain whether lower dose intravenous tissue-type plasminogen activator (tPA) for stroke is as effective and safe as the standard dose. METHODS:We analyzed data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China). Patients who were treate...

journal_title：Stroke

authors： Liao X,Wang Y,Pan Y,Wang C,Zhao X,Wang DZ,Wang C,Liu L,Wang Y,Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China Investigators.

更新日期：2014-08-01 00:00:00

abstract：:Background and Purpose- Persistent depression after ischemic stroke is common in stroke survivors and may be even higher in family caregivers, but few studies have examined depressive symptom levels and their predictors in patient and caregiver groups simultaneously. Methods- Stroke survivors and their family caregive...

journal_title：Stroke

authors： Roth DL,Haley WE,Sheehan OC,Liu C,Clay OJ,Rhodes JD,Judd SE,Dhamoon M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microanatomy studies reveal that most penetrating branches of middle cerebral artery (MCA) arise from the dorsal-superior surface of the trunk. Using high-resolution MRI, we sought to explore the plaque distribution of MCA atherosclerosis and its clinical relevance in relation to the orifices of ...

journal_title：Stroke

authors： Xu WH,Li ML,Gao S,Ni J,Zhou LX,Yao M,Peng B,Feng F,Jin ZY,Cui LY

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is unclear which harmonic imaging mode (power Doppler or gray-scale imaging) is superior and which measuring method is the most robust for the description of brain perfusion. METHODS:We performed an animal study on 6 beagles through the intact skull using a SONOS 5500 device and Optison injec...

journal_title：Stroke

authors： Seidel G,Algermissen C,Christoph A,Katzer T,Kaps M

更新日期：2000-07-01 00:00:00

abstract：:Contrast-enhanced computed tomography of the neck permits low-risk evaluation of morphologic complications of carotid plaque, including (and foremost) calcification. To investigate the patterns and clinical significance of calcified deposits in the cervical carotid arteries using computed tomography we studied 40 pati...

journal_title：Stroke

authors： Culebras A,Otero C,Toledo JR,Rubin BS

更新日期：1989-11-01 00:00:00

abstract：:Background and Purpose- Despite evidence to support the prescription of antihypertensive medications before hospital discharge to promote medication adherence and prevent recurrent events, many patients with stroke miss out on these medications at discharge. We aimed to examine patient, clinical, and system-level diff...

journal_title：Stroke

authors： Dalli LL,Kim J,Thrift AG,Andrew NE,Lannin NA,Anderson CS,Grimley R,Katzenellenbogen JM,Boyd J,Lindley RI,Pollack M,Jude M,Durairaj R,Shah D,Cadilhac DA,Kilkenny MF

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is currently no consensus on (1) the percentage of patients who develop spasticity after ischemic stroke, (2) the relation between spasticity and initial clinical findings after acute stroke, and (3) the impact of spasticity on activities of daily living and health-related quality of life. ...

journal_title：Stroke

authors： Urban PP,Wolf T,Uebele M,Marx JJ,Vogt T,Stoeter P,Bauermann T,Weibrich C,Vucurevic GD,Schneider A,Wissel J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lacunar syndromes correlate with a lacunar stroke on imaging in 50% to 60% of cases. Computed tomography perfusion (CTP) is becoming the preferred imaging modality for acute stroke triage. We aimed to estimate the sensitivity, specificity, and predictive values for noncontrast computed tomography...

journal_title：Stroke

authors： Garcia-Esperon C,Visser M,Churilov L,Miteff F,Bivard A,Lillicrap T,Levi CR,Spratt NJ,Parsons MW

更新日期：2021-01-01 00:00:00

abstract：:Platelet activating factor, a potent inducer of in vivo platelet activation and thrombosis, has been shown to be excessively active in acute ischemic stroke patients. Therefore, we studied the effect of aspirin/dipyridamole therapy in inhibiting platelet activating factor-induced platelet activation in acute ischemic ...

journal_title：Stroke

authors： Joseph R,Welch KM,D'Andrea G

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial direct current stimulation is emerging as a promising tool for the treatment of several neurological conditions, including cerebral ischemia. The therapeutic role of this noninvasive treatment is, however, limited to chronic phases of stroke. We thus ought to investigate whether diff...

journal_title：Stroke

authors： Peruzzotti-Jametti L,Cambiaghi M,Bacigaluppi M,Gallizioli M,Gaude E,Mari S,Sandrone S,Cursi M,Teneud L,Comi G,Musco G,Martino G,Leocani L

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is associated with increased risk of dementia. There has been a decline in mortality from stroke among persons 65 and over in recent decades in the US. It is not clear, however, how this process has affected incidence of various dementias. METHODS:We evaluated over time changes in stroke ...

journal_title：Stroke

authors： Ukraintseva S,Sloan F,Arbeev K,Yashin A

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed cerebral ischemia and infarction due to reduced CBF remains the leading cause of poor outcome after aneurysmal subarachnoid hemorrhage. Hypertonic saline (HS) is associated with an increase in CBF. This study explores whether CBF enhancement with HS in patients with poor-grade subarachnoi...

journal_title：Stroke

authors： Al-Rawi PG,Tseng MY,Richards HK,Nortje J,Timofeev I,Matta BF,Hutchinson PJ,Kirkpatrick PJ

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:An increase in intima-media thickness (IMT) in the common carotid artery (CCA) is commonly used as a marker of atherosclerosis. The purpose of this study was to investigate the relationship between IMT in the CCA and atherosclerosis in the carotid bifurcation. METHODS:182 consecutive patients (m...

journal_title：Stroke

authors： Rosfors S,Hallerstam S,Jensen-Urstad K,Zetterling M,Carlström C

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A high incidence of arteriovenous malformations (AVMs) is associated with hereditary hemorrhagic telangiectasia type 1. Endoglin, the gene mutated in this disorder, is expressed at reduced levels on blood vessels of these patients. Since endoglin is a component of the transforming growth factor-b...

journal_title：Stroke

authors： Matsubara S,Bourdeau A,terBrugge KG,Wallace C,Letarte M

更新日期：2000-11-01 00:00:00

abstract：:Background and Purpose- Ischemic stroke impairs endoplasmic reticulum (ER) function, causes ER stress, and activates the unfolded protein response. The unfolded protein response consists of 3 branches controlled by ER stress sensor proteins, which include PERK (protein kinase RNA-like ER kinase). Activated PERK phosph...

journal_title：Stroke

authors： Wang YC,Li X,Shen Y,Lyu J,Sheng H,Paschen W,Yang W

更新日期：2020-05-01 00:00:00