Cerebral hypoperfusion during acute Kawasaki disease.


BACKGROUND AND PURPOSE:Kawasaki disease is a febrile disease of children notable for systemic vasculitis. There have been many previous reports of various complications, including disorders of the central nervous system. We evaluated cerebral perfusion during the acute stage in patients with Kawasaki disease. METHODS:Single-photon emission-computed tomography (SPECT) with 99mTc-hexamethylpropyleneamine oxime was performed in 21 children with acute stage Kawasaki disease. Follow-up SPECT and MRI were performed about 1 month after the first SPECT in patients who exhibited abnormal SPECT findings during the acute stage. RESULTS:In 6 of 21 children SPECT imaging demonstrated localized cerebral hypoperfusion without abnormal neurological findings or clinical symptoms, and the follow-up SPECT and MRI approximately 1 month after the first SPECT revealed no abnormalities. CONCLUSIONS:Some patients with Kawasaki disease have transient localized cerebral hypoperfusion at the acute stage.






Ichiyama T,Nishikawa M,Hayashi T,Koga M,Tashiro N,Furukawa S




Has Abstract


1998-07-01 00:00:00














  • Coffee and tea consumption and risk of stroke subtypes in male smokers.

    abstract:BACKGROUND AND PURPOSE:Coffee and tea consumption could potentially reduce the risk of stroke because these beverages have antioxidant properties, and coffee may improve insulin sensitivity. We examined the associations of coffee and tea consumption with risk of stroke subtypes. METHODS:We used prospective data from t...


    pub_type: 杂志文章


    authors: Larsson SC,Männistö S,Virtanen MJ,Kontto J,Albanes D,Virtamo J

    更新日期:2008-06-01 00:00:00

  • Baseline Predictors of Poor Outcome in Patients Too Good to Treat With Intravenous Thrombolysis.

    abstract:BACKGROUND AND PURPOSE:Several studies have reported poor outcomes in patients too good to treat with intravenous thrombolysis because of mild or rapidly improving symptoms. We sought to determine baseline clinical and imaging predictors of poor outcome in these patients. METHODS:Among 3950 consecutive stroke admissio...


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    authors: Ali SF,Siddiqui K,Ay H,Silverman S,Singhal A,Viswanathan A,Rost N,Lev M,Schwamm LH

    更新日期:2016-12-01 00:00:00

  • Neuropsychometric changes in patients after carotid endarterectomy.

    abstract:BACKGROUND AND PURPOSE:One hundred twelve patients undergoing elective carotid endarterectomy for symptomatic and asymptomatic carotid artery stenosis were enrolled in a prospective study to evaluate the incidence of change in postoperative cerebral function. METHODS:Patients were evaluated preoperatively and postoper...


    pub_type: 杂志文章


    authors: Heyer EJ,Adams DC,Solomon RA,Todd GJ,Quest DO,McMahon DJ,Steneck SD,Choudhri TF,Connolly ES

    更新日期:1998-06-01 00:00:00

  • Multiple Soluble Components of the Glycocalyx Are Increased in Patient Plasma After Ischemic Stroke.

    abstract::Background and Purpose- The GLX (glycocalyx) is a protein/polysaccharide meshwork at the cellular surface. Consisting largely of glycosaminoglycans and proteoglycans, the GLX can shed in response to stress. In this study, we assay 11 components of the GLX in plasma from patients with ischemic stroke from a longitudina...


    pub_type: 杂志文章


    authors: DellaValle B,Hasseldam H,Johansen FF,Iversen HK,Rungby J,Hempel C

    更新日期:2019-10-01 00:00:00

  • The arctic ground squirrel brain is resistant to injury from cardiac arrest during euthermia.

    abstract:BACKGROUND AND PURPOSE:Hetereothermic mammals tolerate hypoxia during euthermy and torpor, and evidence suggests this tolerance may extend beyond hypoxia to cerebral ischemia. During hibernation, CA1 hippocampal neurons endure extreme fluctuations in cerebral blood flow during transitions into and out of torpor as well...


    pub_type: 杂志文章


    authors: Dave KR,Prado R,Raval AP,Drew KL,Perez-Pinzon MA

    更新日期:2006-05-01 00:00:00

  • Misdiagnosis of symptomatic cerebral aneurysm. Prevalence and correlation with outcome at four institutions.

    abstract:BACKGROUND AND PURPOSE:It is not known what fraction of patients with symptomatic cerebral aneurysms are misdiagnosed at initial medical presentation. It is also not clear whether misdiagnosed patients more frequently deteriorate before definitive aneurysm diagnosis and therapy or achieve a poorer outcome than correctl...


    pub_type: 杂志文章


    authors: Mayer PL,Awad IA,Todor R,Harbaugh K,Varnavas G,Lansen TA,Dickey P,Harbaugh R,Hopkins LN

    更新日期:1996-09-01 00:00:00

  • Late outcome of patients with premature carotid atherosclerosis after carotid endarterectomy.

    abstract:BACKGROUND AND PURPOSE:The durability of carotid endarterectomy (CEA) in young adults with premature carotid atherosclerosis has not been adequately assessed. This study examined the late recurrence and mortality rates in young adults undergoing CEA. METHODS:We studied 42 young patients (mean age, 45.5 +/- 0.5 years) ...


    pub_type: 杂志文章


    authors: Valentine RJ,Myers SI,Hagino RT,Clagett GP

    更新日期:1996-09-01 00:00:00

  • Effect of BQ-123 and tissue plasminogen activator on vasospasm after subarachnoid hemorrhage in monkeys.

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    pub_type: 杂志文章


    authors: Kim CJ,Bassiouny M,Macdonald RL,Weir B,Johns LM

    更新日期:1996-09-01 00:00:00

  • Chronic depression of glucose metabolism in postischemic rat brains.

    abstract:BACKGROUND AND PURPOSE:The present investigation aimed to quantify functional activity in rat brains after long-term recovery from transient forebrain ischemia. METHODS:With the use of the [14C]2-deoxyglucose method, local cerebral glucose utilization was measured in 62 cortical and subcortical brain regions in postis...


    pub_type: 杂志文章


    authors: Beck T,Goller HJ,Wree A

    更新日期:1995-06-01 00:00:00

  • Which time-to-peak threshold best identifies penumbral flow? A comparison of perfusion-weighted magnetic resonance imaging and positron emission tomography in acute ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:In acute ischemic stroke, the hypoperfused but viable tissue is the main therapeutic target. In clinical routine, time-to-peak (TTP) maps are frequently used to estimate the hemodynamic compromise and to calculate the mismatch volume. We evaluated the accuracy of TTP maps to identify penumbral fl...


    pub_type: 杂志文章


    authors: Sobesky J,Zaro Weber O,Lehnhardt FG,Hesselmann V,Thiel A,Dohmen C,Jacobs A,Neveling M,Heiss WD

    更新日期:2004-12-01 00:00:00

  • Dissociation of vasospasm and secondary effects of experimental subarachnoid hemorrhage by clazosentan.

    abstract:BACKGROUND AND PURPOSE:Endothelin receptor antagonists such as clazosentan decrease large-artery vasospasm after experimental and clinical subarachnoid hemorrhage. We used clazosentan to gain insight into the pathophysiology of subarachnoid hemorrhage by determining if decreasing vasospasm is associated with alleviatio...


    pub_type: 杂志文章


    authors: Sabri M,Ai J,Macdonald RL

    更新日期:2011-05-01 00:00:00

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    pub_type: 杂志文章


    authors: Alberts MJ,Chaturvedi S,Graham G,Hughes RL,Jamieson DG,Krakowski F,Raps E,Scott P

    更新日期:1998-11-01 00:00:00

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    abstract:BACKGROUND AND PURPOSE:Determinants of long-term outcome are not well defined in minor stroke patients. This study aims to evaluate which factors are independent long-term predictors of death and major stroke recurrence in a cohort of minor ischemic strokes. METHODS:A cohort of 322 patients with first-ever minor ische...


    pub_type: 杂志文章


    authors: Prencipe M,Culasso F,Rasura M,Anzini A,Beccia M,Cao M,Giubilei F,Fieschi C

    更新日期:1998-01-01 00:00:00

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    pub_type: 杂志文章


    authors: Morimoto Y,Morimoto Y,Warner DS,Pearlstein RD

    更新日期:1996-08-01 00:00:00

  • Clomethiazole Acute Stroke Study in ischemic stroke (CLASS-I): final results.

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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Lyden P,Shuaib A,Ng K,Levin K,Atkinson RP,Rajput A,Wechsler L,Ashwood T,Claesson L,Odergren T,Salazar-Grueso E,CLASS-I\/H\/T Investigators.

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    authors: Mazighi M,Meseguer E,Labreuche J,Amarenco P

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  • Sympathetic nervous activity and myocardial damage immediately after subarachnoid hemorrhage in a unique animal model.

    abstract:BACKGROUND AND PURPOSE:Obvious cardiac dysfunction, including ECG abnormalities and left ventricular asynergy, is known to develop after subarachnoid hemorrhage (SAH). To clarify the close relationship between myocardial damage and sympathetic nervous activity immediately after SAH, a novel experimental animal model wa...


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    authors: Masuda T,Sato K,Yamamoto S,Matsuyama N,Shimohama T,Matsunaga A,Obuchi S,Shiba Y,Shimizu S,Izumi T

    更新日期:2002-06-01 00:00:00

  • Strictly Lobar Microbleeds Reflect Amyloid Angiopathy Regardless of Cerebral and Cerebellar Compartments.

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  • Prognosis in middle cerebral artery stenosis.

    abstract::Among 21 patients with angiographically demonstrated stenosis of the middle cerebral artery (MCA) 14 presented with a stroke and 7 with transient ischaemic attacks (TIAs). Of the former 4 had further strokes (3 fatal); of the latter one had a fatal stroke. Only 2 of the 21 patients had TIAs during the follow-up period...


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    authors: Corston RN,Kendall BE,Marshall J

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  • Deconstruction of Interhospital Transfer Workflow in Large Vessel Occlusion: Real-World Data in the Thrombectomy Era.

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    authors: Ng FC,Low E,Andrew E,Smith K,Campbell BCV,Hand PJ,Crompton DE,Wijeratne T,Dewey HM,Choi PM

    更新日期:2017-07-01 00:00:00

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    pub_type: 杂志文章


    authors: Tomita I,Sano M,Serizawa S,Ohta K,Katou M

    更新日期:1979-05-01 00:00:00

  • Effects of fosinopril and pravastatin on carotid intima-media thickness in subjects with increased albuminuria.

    abstract:BACKGROUND AND PURPOSE:Elevated urinary albumin excretion (UAE) is associated with an increased carotid intima-media thickness (IMT). Because angiotensin-converting enzyme inhibitors as well as statins have been shown to lower UAE and the progression of IMT, we assessed the effects of fosinopril and pravastatin on caro...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Asselbergs FW,van Roon AM,Hillege HL,de Jong PE,Gans RO,Smit AJ,van Gilst WH,PREVEND IT Investigators.

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    pub_type: 杂志文章


    authors: Smith WL,DeWitt DL,Shimokawa T,Kraemer SA,Meade EA

    更新日期:1990-12-01 00:00:00

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    pub_type: 杂志文章


    authors: Marini C,De Santis F,Sacco S,Russo T,Olivieri L,Totaro R,Carolei A

    更新日期:2005-06-01 00:00:00

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    pub_type: 杂志文章,meta分析


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    pub_type: 杂志文章


    authors: Ohara T,Kokubo Y,Toyoda K,Watanabe M,Koga M,Nakamura S,Nagatsuka K,Minematsu K,Nakagawa M,Miyamoto Y

    更新日期:2013-12-01 00:00:00

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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


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    pub_type: 杂志文章


    authors: Takano T,Nagatsuka K,Ohnishi Y,Takamitsu Y,Matsuo H,Matsumoto M,Kimura K,Kamada T

    更新日期:1988-07-01 00:00:00