Cerebral hypoperfusion during acute Kawasaki disease.

Abstract:

BACKGROUND AND PURPOSE:Kawasaki disease is a febrile disease of children notable for systemic vasculitis. There have been many previous reports of various complications, including disorders of the central nervous system. We evaluated cerebral perfusion during the acute stage in patients with Kawasaki disease. METHODS:Single-photon emission-computed tomography (SPECT) with 99mTc-hexamethylpropyleneamine oxime was performed in 21 children with acute stage Kawasaki disease. Follow-up SPECT and MRI were performed about 1 month after the first SPECT in patients who exhibited abnormal SPECT findings during the acute stage. RESULTS:In 6 of 21 children SPECT imaging demonstrated localized cerebral hypoperfusion without abnormal neurological findings or clinical symptoms, and the follow-up SPECT and MRI approximately 1 month after the first SPECT revealed no abnormalities. CONCLUSIONS:Some patients with Kawasaki disease have transient localized cerebral hypoperfusion at the acute stage.

journal_name

Stroke

journal_title

Stroke

authors

Ichiyama T,Nishikawa M,Hayashi T,Koga M,Tashiro N,Furukawa S

doi

10.1161/01.str.29.7.1320

subject

Has Abstract

pub_date

1998-07-01 00:00:00

pages

1320-1

issue

7

eissn

0039-2499

issn

1524-4628

journal_volume

29

pub_type

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