Depressive Symptoms After Ischemic Stroke: Population-Based Comparisons of Patients and Caregivers With Matched Controls.

Abstract:

:Background and Purpose- Persistent depression after ischemic stroke is common in stroke survivors and may be even higher in family caregivers, but few studies have examined depressive symptom levels and their predictors in patient and caregiver groups simultaneously. Methods- Stroke survivors and their family caregivers (205 dyads) were enrolled from the national REGARDS study (Reasons for Geographic and Racial Differences in Stroke) into the CARES study (Caring for Adults Recovering from the Effects of Stroke) ≈9 months after a first-time ischemic stroke. Demographically matched stroke-free dyads (N=205) were also enrolled. Participants were interviewed by telephone, and depressive symptoms were assessed with the 20-item Center for Epidemiological Studies-Depression scale. Results- Significant elevations in depressive symptoms (Ps<0.03) were observed for stroke survivors (M=8.38) and for their family caregivers (M=6.42) relative to their matched controls (Ms=5.18 and 4.62, respectively). Stroke survivors reported more symptoms of depression than their caregivers (P=0.008). No race or sex differences were found, but differential prediction of depressive symptom levels was found across patients and caregivers. Younger age and having an older caregiver were associated with more depressive symptoms in stroke survivors while being a spouse caregiver and reporting fewer positive aspects of caregiving were associated with more depressive symptoms in caregivers. The percentage of caregivers at risk for clinically significant depression was lower in this population-based sample (12%) than in previous studies of caregivers from convenience or clinical samples. Conclusions- High depressive symptom levels are common 9 months after first-time ischemic strokes for stroke survivors and family caregivers, but rates of depressive symptoms at risk for clinical depression were lower for caregivers than previously reported. Predictors of depression differ for patients and caregivers, and standards of care should incorporate family caregiving factors.

journal_name

Stroke

journal_title

Stroke

authors

Roth DL,Haley WE,Sheehan OC,Liu C,Clay OJ,Rhodes JD,Judd SE,Dhamoon M

doi

10.1161/STROKEAHA.119.027039

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

54-60

issue

1

eissn

0039-2499

issn

1524-4628

journal_volume

51

pub_type

杂志文章

相关文献

STROKE文献大全
  • Concomitant headache influences long-term prognosis after acute cerebral ischemia of noncardioembolic origin.

    abstract:BACKGROUND AND PURPOSE:Acute cerebral ischemia is frequently associated with headache. It is unknown whether concomitant headache reflects a partly different pathogenesis, and thus, may influence long-term prognosis after stroke. Here, we compared the long-term risk of recurrent vascular events in patients in whom a tr...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.113.002217

    authors: Maino A,Algra A,Koudstaal PJ,van Zwet EW,Ferrari MD,Wermer MJ,LiLAC Study Group.

    更新日期:2013-09-01 00:00:00

  • Lipoprotein-associated phospholipase A2 and C-reactive protein for risk-stratification of patients with TIA.

    abstract:BACKGROUND AND PURPOSE:Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a marker of unstable atherosclerotic plaque, and is predictive of both primary and secondary stroke in population-based studies. METHODS:We conducted a prospective study of patients with acute TIA who presented to the ED. Clinical risk sco...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.109.553545

    authors: Cucchiara BL,Messe SR,Sansing L,MacKenzie L,Taylor RA,Pacelli J,Shah Q,Kasner SE

    更新日期:2009-07-01 00:00:00

  • Electrical stimulation of the cerebral cortex exerts antiapoptotic, angiogenic, and anti-inflammatory effects in ischemic stroke rats through phosphoinositide 3-kinase/Akt signaling pathway.

    abstract:BACKGROUND AND PURPOSE:Neuroprotective effects of electric stimulation have been recently shown in ischemic stroke, but the underlying mechanisms remain poorly understood. METHODS:Adult Wistar rats weighing 200 to 250 g received occlusion of the right middle cerebral artery for 90 minutes. At 1 hour after reperfusion,...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.109.563627

    authors: Baba T,Kameda M,Yasuhara T,Morimoto T,Kondo A,Shingo T,Tajiri N,Wang F,Miyoshi Y,Borlongan CV,Matsumae M,Date I

    更新日期:2009-11-01 00:00:00

  • Circadian fluctuations in onset of subarachnoid hemorrhage. New data on aneurysmal and perimesencephalic hemorrhage and a systematic review.

    abstract:BACKGROUND AND PURPOSE:Several studies have found a morning peak in onset of stroke. A similar peak has been suggested for subarachnoid hemorrhage (SAH), which seems in contradiction with the physical activities associated with aneurysmal rupture. Most studies included only a few patients with SAH. We analyzed time of ...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.str.28.4.805

    authors: Vermeer SE,Rinkel GJ,Algra A

    更新日期:1997-04-01 00:00:00

  • Treatment of hyperglycemia in ischemic stroke (THIS): a randomized pilot trial.

    abstract:BACKGROUND AND PURPOSE:Hyperglycemia may worsen brain injury during acute cerebral infarction. We tested the feasibility and tolerability of aggressive hyperglycemia correction with intravenous insulin compared with usual care during acute cerebral infarction. METHODS:We conducted a randomized, multicenter, blinded pi...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1161/STROKEAHA.107.493544

    authors: Bruno A,Kent TA,Coull BM,Shankar RR,Saha C,Becker KJ,Kissela BM,Williams LS

    更新日期:2008-02-01 00:00:00

  • Leukoaraiosis and stroke.

    abstract::Leukoaraiosis is a common finding in stroke patients and has been strongly associated with risk of incident stroke and dementia. Leukoaraiosis may also be an independent predictor of stroke outcomes. There is increasing evidence from neuroimaging to support the concept that some leukoaraiosis is caused by white matter...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/STROKEAHA.110.596056

    authors: Smith EE

    更新日期:2010-10-01 00:00:00

  • Role of extracellular Ca2+ in subarachnoid hemorrhage-induced spasm of the rabbit basilar artery.

    abstract:BACKGROUND AND PURPOSE:The role of extracellular Ca2+ in the maintenance of chronic vasospasm after subarachnoid hemorrhage (SAH) is largely unknown. Indeed, studies thus far have been limited to demonstrations that L-type Ca(2+)-channel antagonists were unable to reverse the spasm. This study tested whether SAH-induce...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.27.10.1896

    authors: Zuccarello M,Boccaletti R,Tosun M,Rapoport RM

    更新日期:1996-10-01 00:00:00

  • Fatal infantile polyarteritis nodosa with predominant central nervous system involvement.

    abstract:BACKGROUND:Infantile polyarteritis nodosa usually presents in children under 2 years of age as a multiorgan system disease with signs of congestive heart failure or renal failure. This disease and Kawasaki disease may share certain clinical and pathological features. CASE DESCRIPTION:We describe a child who first pres...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.26.4.699

    authors: Engel DG,Gospe SM Jr,Tracy KA,Ellis WG,Lie JT

    更新日期:1995-04-01 00:00:00

  • Third European Stroke Science Workshop.

    abstract::Lake Eibsee, Garmisch-Partenkirchen, November 19 to 21, 2015: The European Stroke Organization convened >120 stroke experts from 27 countries to discuss latest results and hot topics in clinical, translational, and basic stroke research. Since its inception in 2011, the European Stroke Science Workshop has become a co...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.013516

    authors: Dichgans M,Planas AM,Biessels GJ,van der Worp B,Sudlow C,Norrving B,Lees K,Mattle HP

    更新日期:2016-07-01 00:00:00

  • Nitric oxide and the cerebral circulation.

    abstract:BACKGROUND:Nitric oxide (NO) is a potent vasodilator that was initially described as the mediator of endothelium-dependent relaxation (endothelium-derived relaxing factor, EDRF). It is now known that NO is produced by a variety of other cell types. SUMMARY OF REVIEW:Endothelium produces NO (EDRF) under basal condition...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.str.25.3.692

    authors: Faraci FM,Brian JE Jr

    更新日期:1994-03-01 00:00:00

  • Cerebral infarction immediately after ingestion of hydrogen peroxide solution.

    abstract:BACKGROUND:We report the clinical and neuroimaging findings of a patient who sustained multiple cerebral infarcts after the ingestion of concentrated hydrogen peroxide solution sold as a "health food" product. CASE DESCRIPTION:An 84-year-old man sustained focal neurological deficits immediately after ingesting 30 mL o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.5.1065

    authors: Sherman SJ,Boyer LV,Sibley WA

    更新日期:1994-05-01 00:00:00

  • Fibrinogen concentration and risk of ischemic stroke and acute coronary events in 5113 patients with transient ischemic attack and minor ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:Fibrinogen is an independent risk factor for coronary events in population-based studies and in patients with coronary heart disease, but there is uncertainty about prediction of stroke, particularly in secondary prevention. METHODS:We studied unpublished data from 3 prospective studies of patie...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000141701.36371.d1

    authors: Rothwell PM,Howard SC,Power DA,Gutnikov SA,Algra A,van Gijn J,Clark TG,Murphy MF,Warlow CP

    更新日期:2004-10-01 00:00:00

  • Arterial baroreflex: a novel target for preventing stroke in rat hypertension.

    abstract:BACKGROUND AND PURPOSE:Arterial baroreflex is one of the most important mechanisms in the regulation of cardiovascular activities. Arterial baroreflex function can be expressed as baroreflex sensitivity (BRS). The present study was designed to test 2 hypotheses: (1) BRS is a new independent predictor for the incidence ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.106.480061

    authors: Liu AJ,Ma XJ,Shen FM,Liu JG,Chen H,Su DF

    更新日期:2007-06-01 00:00:00

  • Intracarotid saline infusion improves outcome from incomplete ischemia in rats.

    abstract::Previous studies suggest that rheological changes associated with ischemia may produce postischemic hypoperfusion. We tested whether intracarotid or intravenous infusions of saline improve neurological outcome from incomplete cerebral ischemia in rats. Rats were anesthetized with 1.4% isoflurane in air, and ischemia w...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.22.6.797

    authors: Hoffman WE,Ferguson L,Thomas C,Albrecht RF

    更新日期:1991-06-01 00:00:00

  • Early Imaging Prediction of Malignant Cerebellar Edema Development in Acute Ischemic Stroke.

    abstract:BACKGROUND AND PURPOSE:Malignant cerebellar edema (MCE) is a life-threatening complication of acute ischemic stroke that requires timely diagnosis and management. Aim of this study was to identify imaging predictors in initial multiparametric computed tomography (CT), including whole-brain CT perfusion (WB-CTP). METHO...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.117.018237

    authors: Fabritius MP,Thierfelder KM,Meinel FG,Othman AE,Dorn F,Sabel BO,Scheffler P,Ertl-Wagner B,Sommer WH,Kunz WG

    更新日期:2017-09-01 00:00:00

  • Impact of admission hyperglycemia on stroke outcome after thrombolysis: risk stratification in relation to time to reperfusion.

    abstract:BACKGROUND AND PURPOSE:We evaluated the impact of admission hyperglycemia (HG) on stroke outcome in relation to the timing of reperfusion in patients treated with tissue plasminogen activator (tPA). METHODS:We studied 138 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000143728.45516.c6

    authors: Alvarez-Sabín J,Molina CA,Ribó M,Arenillas JF,Montaner J,Huertas R,Santamarina E,Rubiera M

    更新日期:2004-11-01 00:00:00

  • Impact of chronic kidney disease on carotid atherosclerosis according to blood pressure category: the Suita study.

    abstract:BACKGROUND AND PURPOSE:We aimed to clarify the association of chronic kidney disease (CKD) with carotid atherosclerosis and the impact of CKD on carotid atherosclerosis according to blood pressure categories in an urban general population. METHODS:We studied 3466 Japanese individuals (35-93 years old) in the Suita Stu...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.113.002957

    authors: Ohara T,Kokubo Y,Toyoda K,Watanabe M,Koga M,Nakamura S,Nagatsuka K,Minematsu K,Nakagawa M,Miyamoto Y

    更新日期:2013-12-01 00:00:00

  • Single limb exercise induces femoral artery remodeling and improves blood flow in the hemiparetic leg poststroke.

    abstract:BACKGROUND AND PURPOSE:After stroke, individuals have decreased mobility of the hemiparetic leg, which demands less muscle oxygen consumption; thus, blood flow decreases. The purpose of this study was to determine the effect of single limb exercise (SLE) on femoral artery blood flow, diameter, and peak flow velocity in...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/STROKEAHA.109.550889

    authors: Billinger SA,Gajewski BJ,Guo LX,Kluding PM

    更新日期:2009-09-01 00:00:00

  • Altered Fibrin Clot Properties in Patients With Cerebral Venous Sinus Thrombosis: Association With the Risk of Recurrence.

    abstract:BACKGROUND AND PURPOSE:Venous thromboembolism and ischemic stroke are associated with unfavorable fibrin clot structure and function. We hypothesized that denser fibrin networks displaying impaired lysability characterize patients with cerebral venous sinus thrombosis (CVST). METHODS:We assessed plasma fibrin clot pro...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.009528

    authors: Siudut J,Świat M,Undas A

    更新日期:2015-09-01 00:00:00

  • Clinical Outcomes of Transplanted Modified Bone Marrow-Derived Mesenchymal Stem Cells in Stroke: A Phase 1/2a Study.

    abstract:BACKGROUND AND PURPOSE:Preclinical data suggest that cell-based therapies have the potential to improve stroke outcomes. METHODS:Eighteen patients with stable, chronic stroke were enrolled in a 2-year, open-label, single-arm study to evaluate the safety and clinical outcomes of surgical transplantation of modified bon...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.012995

    authors: Steinberg GK,Kondziolka D,Wechsler LR,Lunsford LD,Coburn ML,Billigen JB,Kim AS,Johnson JN,Bates D,King B,Case C,McGrogan M,Yankee EW,Schwartz NE

    更新日期:2016-07-01 00:00:00

  • Tactile extinction and functional status after stroke. A preliminary investigation.

    abstract:BACKGROUND AND PURPOSE:Research has identified a number of factors associated with poststroke recovery, but the prediction of long-term functional outcome remains an uncertain endeavor. In previous work, extinction to tactile, double-simultaneous stimulation has been shown to have short-term predictive utility. The pre...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.10.1973

    authors: Rose L,Bakal DA,Fung TS,Farn P,Weaver LE

    更新日期:1994-10-01 00:00:00

  • Transcranial Doppler detection of microemboli during percutaneous transluminal coronary angioplasty.

    abstract:BACKGROUND AND PURPOSE:The use of percutaneous transluminal coronary angioplasty (PTCA) to treat coronary artery disease is now commonplace. The occurrence of microemboli during invasive procedures such as cardiac angiography and bypass surgery is well documented, although neurological complications are relatively unco...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.11.2367

    authors: Bladin CF,Bingham L,Grigg L,Yapanis AG,Gerraty R,Davis SM

    更新日期:1998-11-01 00:00:00

  • Association Between Thrombus Perviousness Assessed on Computed Tomography and Stroke Cause.

    abstract:BACKGROUND AND PURPOSE:A recent study proposed that thrombus perviousness (TP)-the degree to which contrast agents penetrate the thrombus in an occluded vessel measured on noncontrast computed tomography (NCCT) and CT angiography-may be associated with cardioembolic stroke cause with high specificity. Our aim was to in...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.031148

    authors: Kufner A,Erdur H,Endres M,Nolte CH,Scheel M,Schlemm L

    更新日期:2020-12-01 00:00:00

  • Prestroke modified rankin stroke scale has moderate interobserver reliability and validity in an acute stroke setting.

    abstract:BACKGROUND AND PURPOSE:The modified Rankin Scale (mRS) is the recommended functional outcome assessment in stroke trials. Utility of mRS may be limited by interobserver variability. prestroke function, described using mRS, is often used as trial entry criterion. We assessed the reliability and validity of prestroke mRS...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.112.670422

    authors: Fearon P,McArthur KS,Garrity K,Graham LJ,McGroarty G,Vincent S,Quinn TJ

    更新日期:2012-12-01 00:00:00

  • Spontaneous improvement after acute ischemic stroke. A pilot study.

    abstract::Recent clinical studies emphasize the importance of early (less than 12 hours after onset) treatment of patients with acute ischemic stroke. Therapies have been proposed as being effective because of early clinical improvement. The frequency and degree of spontaneous improvement in such patients, however, is unknown. ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.21.7.1008

    authors: Biller J,Love BB,Marsh EE 3rd,Jones MP,Knepper LE,Jiang D,Adams HP Jr,Gordon DL

    更新日期:1990-07-01 00:00:00

  • Common carotid artery intima-media thickness progression as a predictor of stroke in multi-ethnic study of atherosclerosis.

    abstract:BACKGROUND AND PURPOSE:Carotid artery intima-media thickness (IMT) is a marker of cardiovascular disease associated with incident stroke. We studied whether IMT rate of change is associated with stroke. METHODS:We studied 5028 participants of the Multi-Ethnic Study of Atherosclerosis (MESA) comprising white, Chinese, ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.111.625186

    authors: Polak JF,Pencina MJ,O'Leary DH,D'Agostino RB

    更新日期:2011-11-01 00:00:00

  • Brain atrophy and cerebral small vessel disease: a prospective follow-up study.

    abstract:BACKGROUND AND PURPOSE:cerebral small vessel disease (SVD) is the most common cause of vascular dementia. Interest in the use of surrogate markers is increasing. The aims of this study were to determine if brain volume was different between patients with SVD and control subjects, whether it correlated with cognition in...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.594267

    authors: Nitkunan A,Lanfranconi S,Charlton RA,Barrick TR,Markus HS

    更新日期:2011-01-01 00:00:00

  • Blend Sign on Computed Tomography: Novel and Reliable Predictor for Early Hematoma Growth in Patients With Intracerebral Hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Early hematoma growth is not uncommon in patients with intracerebral hemorrhage and is an independent predictor of poor functional outcome. The purpose of our study was to report and validate the use of our newly identified computed tomographic (CT) blend sign in predicting early hematoma growth....

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.009185

    authors: Li Q,Zhang G,Huang YJ,Dong MX,Lv FJ,Wei X,Chen JJ,Zhang LJ,Qin XY,Xie P

    更新日期:2015-08-01 00:00:00

  • Patent foramen ovale size and embolic brain imaging findings among patients with ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:Although the cause of stroke among patients with patent foramen ovale (PFO) may be due to paradoxical cerebral embolism (PCE), this mechanism is often difficult to prove. The aim of our study was to evaluate the association between brain imaging findings suggestive of embolism and PFO among ische...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.5.944

    authors: Steiner MM,Di Tullio MR,Rundek T,Gan R,Chen X,Liguori C,Brainin M,Homma S,Sacco RL

    更新日期:1998-05-01 00:00:00

  • Anterior spinal artery aneurysm presenting as a subarachnoid hemorrhage.

    abstract::A woman who presented with a subarachnoid hemorrhage secondary to a ruptured anterior spinal artery aneurysm of the spinal cord is reported. While this is the first report of a ruptured aneurysm of the anterior spinal artery with angiographic confirmation, it emphasizes that occasionally subarachnoid hemorrhage may be...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.12.2.230

    authors: Vincent FM

    更新日期:1981-03-01 00:00:00