Role of the endothelial lining in recurrences after coil embolization: prevention of recanalization by endothelial denudation.

abstract：:Background and Purpose- Disturbance of endoplasmic reticulum (ER) Ca2+ homeostasis causes neuronal cell injury in stroke. By contrast, ischemic preconditioning (IPC)-a brief sublethal ischemic episode affording tolerance to a subsequent ischemic insult-restores ER Ca2+ homeostasis. Under physiological conditions, ER c...

journal_title：Stroke

authors： Secondo A,Petrozziello T,Tedeschi V,Boscia F,Vinciguerra A,Ciccone R,Pannaccione A,Molinaro P,Pignataro G,Annunziato L

更新日期：2019-05-01 00:00:00

abstract：:The effect of prostaglandin E1 on regional cerebral blood flow (rCBF) was studied with the intra-arterial 133Xe method in ten awake patients under local anesthesia. Measurements were taken from 16 areas of a hemisphere in seven patients, from 35 areas of a hemisphere in two patients and from 256 areas of a hemisphere ...

journal_title：Stroke

authors： Olesen J

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Reduction of cerebral blood flow results in several acute metabolic disturbances, including a reduction in Na,K-ATPase activity. The relation between this reduction and the onset of edema is unknown, as is the effect of restoration of blood flow. Therefore, we investigated the role of decreased N...

journal_title：Stroke

authors： Yang GY,Chen SF,Kinouchi H,Chan PH,Weinstein PR

更新日期：1992-09-01 00:00:00

abstract：:Twenty-four cats had an intravenous infusion of either Fluosol or saline and then were subjected to 2 hours of middle cerebral artery occlusion. All the animals infused with Fluosol and one-half the animals infused with saline were ventilated with 100% O2. Tissue oxygen availability and regional cerebral blood flow we...

journal_title：Stroke

authors： Kolluri S,Heros RC,Hedley-Whyte ET,Vonsattel JP,Miller D,Zervas NT

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to determine the 30-day mortality and morbidity of intracerebral hemorrhage in a large metropolitan population and to determine the most important predictors of 30-day outcome. METHODS:We reviewed the medical records and computed tomographic films for all cases of spont...

journal_title：Stroke

authors： Broderick JP,Brott TG,Duldner JE,Tomsick T,Huster G

更新日期：1993-07-01 00:00:00

abstract：:Background and Purpose- Ischemic stroke is one of the leading causes of morbidity and mortality worldwide and a major cause of long-term disability. Recently, long noncoding RNAs have been revealed, which are tightly associated with several human diseases. However, the functions of long noncoding RNAs in ischemic stro...

journal_title：Stroke

authors： Deng Y,Chen D,Wang L,Gao F,Jin B,Lv H,Zhang G,Sun X,Liu L,Mo D,Ma N,Song L,Huo X,Yan T,Miao Z

更新日期：2019-07-01 00:00:00

abstract：:Background and Purpose- The use of oral anticoagulants (OAC) is considered a contra-indication for intravenous thrombolytics as acute treatment of ischemic stroke. However, little is known about the risks and benefits of endovascular treatment in patients on prior OAC. We aim to compare outcomes after endovascular tre...

journal_title：Stroke

authors： Goldhoorn RB,van de Graaf RA,van Rees JM,Lingsma HF,Dippel DWJ,Hinsenveld WH,Postma A,van den Wijngaard I,van Zwam WH,van Oostenbrugge RJ,Roozenbeek B,MR CLEAN Registry Investigators—Group Authors.

更新日期：2020-06-01 00:00:00

abstract：:Clinicopathologic correlations were reviewed in 100 cases of recent cerebral infarctions in the internal carotid artery distribution. The most frequent cause of death was transtentorial herniation, followed in frequency by pneumonia, cardiac causes, and pulmonary embolism. Thirty-six percent of all patients and 47% of...

journal_title：Stroke

authors： Bounds JV,Wiebers DO,Whisnant JP,Okazaki H

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional walk tests such as the 6- and 12-Minute Walk Test (ie, 6MWT and 12MWT, respectively) are submaximal measures used to determine functional capacity in individuals with compromised ability. The purpose of this study was to determine the relationship between these walk tests and measures ...

journal_title：Stroke

authors： Eng JJ,Chu KS,Dawson AS,Kim CM,Hepburn KE

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been proposed that spin trap agents such as N:-t-butyl-phenylnitrone (PBN) may be useful as neuroprotective agents in the treatment of ischemia and stroke. However, to date, there is little information concerning the effectiveness of spin trap agents when administered in combination with t...

journal_title：Stroke

authors： Lapchak PA,Chapman DF,Zivin JA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The absence of a widely available and sensitive diagnostic test for acute cerebral ischemia remains a significant limitation in the diagnosis and management of stroke. The objective of this study was to examine the feasibility of developing a diagnostic panel of blood-borne biochemical markers of...

journal_title：Stroke

authors： Lynch JR,Blessing R,White WD,Grocott HP,Newman MF,Laskowitz DT

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is scant information available on the incidence of transient ischemic attack (TIA) in a defined population. This study defines incidence rates of first TIA and subtypes of TIA during 1985-1989 and compares the incidence to that obtained from a 1960-1972 cohort study. METHODS:Medical record...

journal_title：Stroke

authors： Brown RD Jr,Petty GW,O'Fallon WM,Wiebers DO,Whisnant JP

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Risk-factor modeling has been proposed to identify patients with carotid stenosis who will most benefit from surgery. Validation by independent institutions performing carotid endarterectomy is necessary to determine the applicability of such models to the individual patient. METHODS:A series of...

journal_title：Stroke

authors： Barth A,Bassetti C

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The shape and exact size of lacunar infarcts have been investigated only postmortem. Recent imaging techniques based on triangulation and connectivity can now be used for 3D segmentation of cerebral lesions. The shape and size of lacunar infarcts was investigated using these techniques in 10 cere...

journal_title：Stroke

authors： Hervé D,Mangin JF,Molko N,Bousser MG,Chabriat H

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Proinflammatory cytokines including interleukin-6 (IL-6) are supposed to play a pivotal role in the development of atherosclerosis. A common polymorphism in the promoter of the IL-6 gene (IL-6 -174G>C) affects plasma IL-6 concentrations and has been suggested as a risk factor for cardiovascular d...

journal_title：Stroke

authors： Weger M,Steinbrugger I,Haas A,März W,El-Shabrawi Y,Weger W,Schmut O,Renner W

更新日期：2005-02-01 00:00:00

abstract：:Mild hypothermia is an established neuroprotectant in the laboratory, showing remarkable and consistent effects across multiple laboratories and models of brain injury. At the clinical level, mild hypothermia has shown benefits in patients who have experienced cardiac arrest and in some pediatric populations experienc...

journal_title：Stroke

authors： Yenari MA,Hemmen TM

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral blood flow is coupled to brain metabolism by means of active modulation of cerebrovascular resistance. This homeostatic vasogenic activity is reflected in slow waves of cerebral blood flow velocities (FV) which can also be detected in intracranial pressure (ICP). However, effects of incr...

journal_title：Stroke

authors： Haubrich C,Czosnyka Z,Lavinio A,Smielewski P,Diehl RR,Pickard JD,Czosnyka M

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Enlarged perivascular spaces (EPVS) have been associated with aging, increased stroke risk, decreased cognitive function, and vascular dementia. However, the relationship of EPVS with age-related neuropathologies is not well understood. Therefore, the purpose of this study was to assess the neuro...

journal_title：Stroke

authors： Javierre-Petit C,Schneider JA,Kapasi A,Makkinejad N,Tamhane AA,Leurgans SE,Mehta RI,Barnes LL,Bennett DA,Arfanakis K

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to determine the effects of aging on regional cerebral blood flow and ischemic brain damage in transient cerebral ischemia in rats. METHODS:Five adult (5-6 months) and five aged (18-22 months) female spontaneously hypertensive rats were subjected to 20 minutes of bilateral carotid occl...

journal_title：Stroke

authors： Yao H,Sadoshima S,Ooboshi H,Sato Y,Uchimura H,Fujishima M

更新日期：1991-11-01 00:00:00

abstract：:In 20 patients with acute major cerebral arterial occlusion, follow-up angiograms were obtained to inspect the occluded artery. These angiograms were compared with brain scans in the fourth week after the stroke. The angiograms revealed that frequent recanalization of the occluded arteries occurred within a week after...

journal_title：Stroke

authors： Irino T,Taneda M,Minami T

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anecdotal evidence suggests that the coronavirus disease 2019 (COVID-19) pandemic mitigation efforts may inadvertently discourage patients from seeking treatment for stroke with resultant increased morbidity and mortality. Analysis of regional data, while hospital capacities for acute stroke care...

journal_title：Stroke

authors： Hsiao J,Sayles E,Antzoulatos E,Stanton RJ,Sucharew H,Broderick JP,Demel SL,Flaherty ML,Grossman AW,Kircher C,Kreitzer N,Peariso K,Prestigiacomo CJ,Shirani P,Walsh KB,Lampton H,Adeoye O,Khatri P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The rate of nitric oxide (NO) generation from nitrite is linearly dependent on reductions in oxygen and pH levels. Recently, nitrite-derived NO has been reported to exert a profound protection against liver and heart ischemia-reperfusion injury. In this study, we hypothesized that nitrite would b...

journal_title：Stroke

authors： Jung KH,Chu K,Ko SY,Lee ST,Sinn DI,Park DK,Kim JM,Song EC,Kim M,Roh JK

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence suggests that an alteration in cerebral hemodynamics plays a relevant role in the occurrence of stroke in patients with carotid occlusion. The purpose of the present study was to evaluate the relationships among baseline characteristics, type and number of collateral pathways, cerebral v...

journal_title：Stroke

authors： Vernieri F,Pasqualetti P,Matteis M,Passarelli F,Troisi E,Rossini PM,Caltagirone C,Silvestrini M

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the efficacy of endovascular treatment (EVT) in patients with anterior circulation ischemic stroke (AIS) is well documented, early neurological deterioration after EVT remains a serious issue associated with poor outcome. Besides obvious causes, such as lack of reperfusion, procedural co...

journal_title：Stroke

authors： Girot JB,Richard S,Gariel F,Sibon I,Labreuche J,Kyheng M,Gory B,Dargazanli C,Maier B,Consoli A,Daumas-Duport B,Lapergue B,Bourcier R,ETIS Investigators*.

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The objectives of the present study were to: (1) noninvasively identify white matter reorganization and monitor its progress within 6 weeks after the onset of stroke; and (2) quantitatively investigate the effect of recombinant human erythropoietin treatment on this structural change using in viv...

journal_title：Stroke

authors： Li L,Jiang Q,Ding G,Zhang L,Zhang ZG,Li Q,Panda S,Kapke A,Lu M,Ewing JR,Chopp M

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined sex-specific relationships of smoking with risk of total stroke and stroke subtypes in Asian populations because of the limited data available. METHODS:A total of 19,782 men and 21,500 women aged 40 to 59 years who were free of prior diagnosis of stroke, coronary heart disease, or ca...

journal_title：Stroke

authors： Mannami T,Iso H,Baba S,Sasaki S,Okada K,Konishi M,Tsugane S,Japan Public Health Center-Based Prospective Study on Cancer and Cardiovascular Disease Group.

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In intracerebral hemorrhage (ICH), preexisting cognitive impairment has been identified as a risk factor for increased mortality and morbidity. However, previous studies examined predominantly White populations; therefore, the prevalence and effect of preICH cognitive impairment has not been stud...

journal_title：Stroke

authors： Sawyer RP,Yim E,Coleman E,Demel SL,Sekar P,Woo D

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:NINDS (National Institute of Neurological Disorders and Stroke)-SiGN (Stroke Genetics Network) is an international consortium of ischemic stroke studies that aims to generate high-quality phenotype data to identify the genetic basis of pathogenic stroke subtypes. This analysis characterizes the e...

journal_title：Stroke

authors： Ay H,Arsava EM,Andsberg G,Benner T,Brown RD Jr,Chapman SN,Cole JW,Delavaran H,Dichgans M,Engström G,Giralt-Steinhauer E,Grewal RP,Gwinn K,Jern C,Jimenez-Conde J,Jood K,Katsnelson M,Kissela B,Kittner SJ,Kleindorfer D

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous studies on the hyperdense middle cerebral artery (MCA) sign were conducted using > or =5-mm thickness noncontrast-computed tomography (NCT). The purpose of this study was to compare thin-section NCT with 5-mm NCT in the detection of thrombus in acute ischemic stroke. METHODS:Enrolled we...

journal_title：Stroke

authors： Kim EY,Lee SK,Kim DJ,Suh SH,Kim J,Heo JH,Kim DI

更新日期：2005-12-01 00:00:00

abstract：:The goal of this study was to test the hypothesis that atherosclerosis alters responses of cerebral arteries and the ocular circulation to the activation in vivo of leukocytes and platelets. We measured blood flow to the brain and eye using microspheres and pressure in the cerebral microvessels of normal and atheroscl...

journal_title：Stroke

authors： Faraci FM,Lopez AG,Breese K,Armstrong ML,Heistad DD

更新日期：1991-06-01 00:00:00