ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry.

abstract：:Background and Purpose- If a relationship between stroke etiology and thrombus computed tomography characteristics exists, assessing these characteristics in clinical practice could serve as a useful additional diagnostic tool for the identification of stroke subtype. Our purpose was to study the association of stroke...

journal_title：Stroke

authors： Boodt N,Compagne KCJ,Dutra BG,Samuels N,Tolhuisen ML,Alves HCBR,Kappelhof M,Lycklama À Nijeholt GJ,Marquering HA,Majoie CBLM,Lingsma HF,Dippel DWJ,van der Lugt A,Coinvestigators MR CLEAN Registry.

更新日期：2020-06-01 00:00:00

abstract：:The intact omentum of 13 monkeys was lengthened, placed subcutaneously, and laid on the left cerebral hemisphere prior to occluding the left middle cerebral artery. Two of these 13 monkeys developed left cerebral infarct and a right hemiparesis. Nine other monkeys had their left middle cerebral artery occluded without...

journal_title：Stroke

authors： Goldsmith HS,Duckett S,Chen WF

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is evidence of unequal access to health care interventions even where universal health systems operate. We investigated associations between patients' sociodemographic characteristics and the provision of acute and longer-term stroke care in a multiethnic urban population. METHODS:We used ...

journal_title：Stroke

authors： McKevitt C,Coshall C,Tilling K,Wolfe C

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Apoptotic-like pathways may contribute to brain cell death after intracerebral hemorrhage. In this study, we used a simplified in vitro model of hemoglobin neurotoxicity to map the caspase cascades involved and to document the role of oxidative stress. METHODS:Primary neuronal cultures were obta...

journal_title：Stroke

authors： Wang X,Mori T,Sumii T,Lo EH

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The reproducibility of duplex scan measures of carotid atherosclerosis was evaluated as part of a study assessing the prevalence of carotid disease in elderly adults. METHODS:Doppler measures of blood flow velocity were used to evaluate disease severity, and extent of carotid plaque was scored f...

journal_title：Stroke

authors： Sutton-Tyrrell K,Wolfson SK Jr,Thompson T,Kelsey SF

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined the possibility that activation of the human brain renin-angiotensin system is involved in enhancement of ischemic brain damage using chimeric transgenic mice with human renin (hRN) and human angiotensinogen (hANG) genes. METHODS:Chimeric (hRN/hANG-Tg) mice were generated by mating o...

journal_title：Stroke

authors： Inaba S,Iwai M,Tomono Y,Senba I,Furuno M,Kanno H,Okayama H,Mogi M,Higaki J,Horiuchi M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed paraplegia remains a devastating complication after ischemic spinal cord injury associated with aortic surgery and trauma. Although apoptosis has been implicated in the pathogenesis of delayed neurodegeneration, mechanisms responsible for the delayed paraplegia remain incompletely underst...

journal_title：Stroke

authors： Kakinohana M,Kida K,Minamishima S,Atochin DN,Huang PL,Kaneki M,Ichinose F

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:the association of autosomal-dominant polycystic kidney disease (ADPKD) with intracranial aneurysm (ICAN) is well known but little is known about the characteristics of ICAN in ADPKD. The purpose of this study was to investigate the prevalence and characteristics of ICAN in ADPKD. METHODS:we scr...

journal_title：Stroke

authors： Xu HW,Yu SQ,Mei CL,Li MH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pathophysiology of borderzone infarcts is not well understood. We investigated whether combined diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) could identify pathophysiologically meaningful categories of borderzone infarcts. METHODS:Seventeen patients with borderzone i...

journal_title：Stroke

authors： Chaves CJ,Silver B,Schlaug G,Dashe J,Caplan LR,Warach S

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have previously shown that treatment of acute stroke patients in our stroke unit (SU) compared with treatment in general ward (GWs) improves short- and long-term survival and functional outcome and increases the possibility of earlier discharge to home. The aim of the present study was to iden...

journal_title：Stroke

authors： Indredavik B,Bakke F,Slordahl SA,Rokseth R,Hâheim LL

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In an inner-London teaching hospital, a randomized trial of "conventional" care versus early discharge to community-based therapy found no significant differences in clinical outcomes between patient groups. This report examines the economic consequences of the alternative strategies. METHODS:On...

journal_title：Stroke

authors： Beech R,Rudd AG,Tilling K,Wolfe CD

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The diagnosis of intracranial atherosclerosis requires availability of appropriate imaging techniques. The objective was to evaluate the proportion of European hospitals where imaging techniques necessary to detect intracranial atherosclerosis are available. Method- We randomly selected 886 hospi...

journal_title：Stroke

authors： Balucani C,Leys D,Ringelstein EB,Kaste M,Hacke W,Executive Committee of the European Stroke Initiative.

更新日期：2009-03-01 00:00:00

abstract：:Patients with chronic aphasia were assigned randomly to a group to receive either conventional aphasia therapy or constraint-induced (CI) aphasia therapy, a new therapeutic technique requiring intense practice over a relatively short period of consecutive days. CI aphasia therapy is realized in a communicative therape...

journal_title：Stroke

authors： Pulvermüller F,Neininger B,Elbert T,Mohr B,Rockstroh B,Koebbel P,Taub E

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Animal data suggest the use of beta-human chorionic gonadotropin followed by erythropoietin to promote brain repair after stroke. The current study directly translated these results by evaluating safety of this sequential growth factor therapy through a 3-center, single-dose, open-label, noncontr...

journal_title：Stroke

authors： Cramer SC,Fitzpatrick C,Warren M,Hill MD,Brown D,Whitaker L,Ryckborst KJ,Plon L

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid plaque composition is a major determinant of cerebrovascular events. In the present analysis, we evaluated the relationship between intraplaque hemorrhage (IPH) and a thin/ruptured fibrous cap (TRFC) in moderately stenosed carotid arteries and cerebral infarcts on MRI in the ipsilateral h...

journal_title：Stroke

authors： de Rotte AA,Truijman MT,van Dijk AC,Liem MI,Schreuder FH,van der Kolk AG,de Kruijk JR,Daemen MJ,van der Steen AF,de Borst GJ,Luijten PR,Nederkoorn PJ,Kooi ME,van der Lugt A,Hendrikse J

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pressure-flow relation has been characterized in normal cerebrum, but it has not been studied in cerebrum dependent on collateral flow. The purpose of this investigation was to examine the relation between systemic pressure, regional cerebral blood flow, and middle cerebral artery branch pres...

journal_title：Stroke

authors： Muhonen MG,Sawin PD,Loftus CM,Heistad DD

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fibrocartilaginous embolism from the nucleus pulposus has been reported as a rare cause of spinal cord ischemia. We were unable to find previous reports of embolism from this source to cerebral arteries. CASE DESCRIPTION:A previously healthy 17-year-old girl fell during a basketball game. Left h...

journal_title：Stroke

authors： Toro-González G,Navarro-Román L,Román GC,Cantillo J,Serrano B,Herrera M,Vergara I

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The introduction of cereal grain folic acid fortification in 1998 has reduced homocyst(e)ine (tHcy) concentrations in the US population. We performed a case-control study to determine the risk of stroke and transient ischemic attack (TIA) associated with tHcy and low vitamin status in a postforti...

journal_title：Stroke

authors： Kelly PJ,Shih VE,Kistler JP,Barron M,Lee H,Mandell R,Furie KL

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We evaluated the impact of a primary stroke center (PSC) destination policy in a major metropolitan city and used geographic modeling to evaluate expected changes for a comprehensive stroke center policy. METHODS:We identified suspected stroke emergency medical services encounters from 1/1/2004 ...

journal_title：Stroke

authors： Mullen MT,Pajerowski W,Messé SR,Mechem CC,Jia J,Abboud M,David G,Carr BG,Band R

更新日期：2018-04-01 00:00:00

abstract：:To study the effects of antithrombotic therapy in experimental stroke, we have characterized a baboon model of acute cerebrovascular thrombosis. In this model an inflatable silastic balloon cuff has been implanted by transorbital approach around the right middle cerebral artery (MCA), proximal to the take-off of the l...

journal_title：Stroke

authors： Del Zoppo GJ,Copeland BR,Harker LA,Waltz TA,Zyroff J,Hanson SR,Battenberg E

更新日期：1986-11-01 00:00:00

abstract：:We have investigated the effects of a reduced regional or a reduced body temperature, on pial arteriolar response to a variety of vasoactive stimuli. This has been done by studying the effects of these stimuli on groups of mice with different body temperatures, or with different temperatures of the artificial cerebros...

journal_title：Stroke

authors： Rosenblum WI,Segreti AC

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several prognostic scores have been developed to predict the risk of symptomatic intracranial hemorrhage (sICH) after ischemic stroke thrombolysis. We compared the performance of these scores in a multicenter cohort. METHODS:We merged prospectively collected data of patients with consecutive isc...

journal_title：Stroke

authors： Strbian D,Michel P,Seiffge DJ,Saver JL,Numminen H,Meretoja A,Murao K,Weder B,Forss N,Parkkila AK,Eskandari A,Cordonnier C,Davis SM,Engelter ST,Tatlisumak T

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The antiplatelet agent sarpogrelate is a selective inhibitor of 5-hydroxytryptamine receptors. The purpose of this study was to compare the efficacy and safety of sarpogrelate with those of aspirin in Japanese ischemic stroke patients. METHODS:In total, 1510 patients with recent cerebral infarct...

journal_title：Stroke

authors： Shinohara Y,Nishimaru K,Sawada T,Terashi A,Handa S,Hirai S,Hayashi K,Tohgi H,Fukuuchi Y,Uchiyama S,Yamaguchi T,Kobayashi S,Kondo K,Otomo E,Gotoh F,S-ACCESS Study Group.

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral blood flow after cardiac arrest is reduced during the delayed hypoperfusion phase, while cerebral metabolic rate of oxygen returns to baseline values. Hypocapnia can induce cerebral ischemia in neurosurgical patients who already have reduced cerebral blood flow. The purpose of the presen...

journal_title：Stroke

authors： Buunk G,van der Hoeven JG,Meinders AE

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke symptoms can be very stressful for family caregivers, but most knowledge about the prevalence and stressfulness of stroke-related patient problems is derived from convenience samples. In addition, little is known about perceived benefits of the stroke caregiving experience. The purpose of ...

journal_title：Stroke

authors： Haley WE,Allen JY,Grant JS,Clay OJ,Perkins M,Roth DL

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Astrocytes are potent regulators of brain capillary endothelial cell function. Recently, astrocytes were shown to regulate brain capillary endothelial expression of the fibrinolytic enzyme tissue plasminogen activator (tPA) and the anticoagulant thrombomodulin (TM). To study the mechanism of this...

journal_title：Stroke

authors： Tran ND,Correale J,Schreiber SS,Fisher M

更新日期：1999-08-01 00:00:00

abstract：:Twenty-four cats had an intravenous infusion of either Fluosol or saline and then were subjected to 2 hours of middle cerebral artery occlusion. All the animals infused with Fluosol and one-half the animals infused with saline were ventilated with 100% O2. Tissue oxygen availability and regional cerebral blood flow we...

journal_title：Stroke

authors： Kolluri S,Heros RC,Hedley-Whyte ET,Vonsattel JP,Miller D,Zervas NT

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been reported that National Institutes of Health Stroke Scale (NIHSS) scores correlate poorly with hypoperfused tissue measured by perfusion-weighted imaging (PWI) in nondominant hemisphere stroke. We conducted 2 studies to determine whether tests of hemispatial neglect provide a better me...

journal_title：Stroke

authors： Hillis AE,Wityk RJ,Barker PB,Ulatowski JA,Jacobs MA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Infantile polyarteritis nodosa usually presents in children under 2 years of age as a multiorgan system disease with signs of congestive heart failure or renal failure. This disease and Kawasaki disease may share certain clinical and pathological features. CASE DESCRIPTION:We describe a child who first pres...

journal_title：Stroke

authors： Engel DG,Gospe SM Jr,Tracy KA,Ellis WG,Lie JT

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Most improvement from poststroke aphasia occurs within the first 3 months, but there remains unexplained variability in recovery. Recently, we reported a strong correlation between initial impairment and change scores in motor recovery at 90 days. We wanted to determine whether aphasia recovery (...

journal_title：Stroke

authors： Lazar RM,Minzer B,Antoniello D,Festa JR,Krakauer JW,Marshall RS

更新日期：2010-07-01 00:00:00