The layered fabric of cerebral artery fenestrations.

abstract：:Various concentrations of acetylcholine (ACh) produced dose dependent relaxations of isolated, helical preparations of human cerebral arteries and these responses were blocked by atropine. The median effective concentration (EC50) of ACh was 6.1 +/- 0.2 X 10(-6)M. ACh produced dual responses in isolated dog cerebral a...

journal_title：Stroke

authors： Tsukahara T,Usui H,Taniguchi T,Shimohama S,Fujiwara M,Handa H

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Cardiac involvement in Whipple's disease is not an uncommon phenomenon in autopsies, but its clinical occurrence is often overshadowed by gastrointestinal symptoms. We report a very atypical manifestation of this disorder. SUMMARY OF REPORT:An extraordinary presentation of an extremely long-lasting, culture...

journal_title：Stroke

authors： Naegeli B,Bannwart F,Bertel O

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor inhibition has been hypothesized to provide neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models of a variety of compounds with varying selectivity for AMPA over other...

journal_title：Stroke

authors： Menniti FS,Buchan AM,Chenard BL,Critchett DJ,Ganong AH,Guanowsky V,Seymour PA,Welch WM

更新日期：2003-01-01 00:00:00

abstract：:Seventy-four patients with hypertensive putaminal hemorrhage (HPH) were followed at least 6 months after treatment and estimated by ADL. They were graded according to the state of consciousness on admission. The grading consists of 6 grades: Grade 1, fully conscious; Grade 2, somnolent; Grade 3, stuporous; Grade 4, se...

journal_title：Stroke

authors： Waga S,Yamamoto Y

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hemorrhagic conversion after tissue plasminogen activator (tPA) stroke therapy has been linked with elevations in matrix metalloproteinase-9 (MMP-9) at the neurovascular interface. Here, we test the idea that statins may directly ameliorate tPA-induced MMP-9 dysregulation. METHODS:Recombinant hu...

journal_title：Stroke

authors： Wang S,Lee SR,Guo SZ,Kim WJ,Montaner J,Wang X,Lo EH

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increased amount of therapy seems to be beneficial for motor recovery after stroke. The primary aim of the present study was to evaluate the effect of a 4-week community-based intensive motor training program combined with early supported discharge after initial treatment in a comprehensive strok...

journal_title：Stroke

authors： Askim T,Mørkved S,Engen A,Roos K,Aas T,Indredavik B

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Failure to recanalize predicts mortality in acute ischemic stroke. In the North American Solitaire Acute Stroke registry, we investigated parameters associated with mortality in successfully recanalized patients. METHODS:Logistic regression was used to evaluate baseline characteristics and recan...

journal_title：Stroke

authors： Linfante I,Walker GR,Castonguay AC,Dabus G,Starosciak AK,Yoo AJ,Abou-Chebl A,Britz GW,Marden FA,Alvarez A,Gupta R,Sun CH,Martin C,Holloway WE,Mueller-Kronast N,English JD,Malisch TW,Bozorgchami H,Xavier A,Rai AT,F

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:This systematic review summarizes the effectiveness of mirror therapy for improving motor function, activities of daily living, pain, and visuospatial neglect in patients after stroke. METHODS:We searched the Cochrane Stroke Group’s Trials Register (June 2011), the Cochrane Central Register of Controlled Tr...

journal_title：Stroke

authors： Thieme H,Mehrholz J,Pohl M,Behrens J,Dohle C

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid endarterectomy (CE) has been shown to be beneficial in patients with symptomatic high-grade (70% to 99%) internal carotid artery stenosis. To achieve this benefit, complications must be kept to a minimum. Complications not associated with the procedure itself, but related to medical condi...

journal_title：Stroke

authors： Paciaroni M,Eliasziw M,Kappelle LJ,Finan JW,Ferguson GG,Barnett HJ

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identifying occult coronary artery stenosis may improve secondary prevention of stroke patients. The aim of this study was to derive and validate a simple score to predict severe occult coronary artery stenosis in stroke patients. METHODS:We derived a score from a French hospital-based cohort of...

journal_title：Stroke

authors： Calvet D,Song D,Yoo J,Turc G,Sablayrolles JL,Choi BW,Heo JH,Mas JL

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Potassium channels are important regulators of resting tone in large cerebral arteries, but their activity and distribution may vary according to vessel location and species studied. In the cerebral microcirculation in vivo, however, these channels appear to be silent at rest. Our goal was to det...

journal_title：Stroke

authors： Horiuchi T,Dietrich HH,Tsugane S,Dacey RG Jr

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:White matter hyperintensities (WMH) are frequently seen on neuroimaging of elderly and are associated with cognitive decline and the development of dementia. Yet, the temporal dynamics of conversion of normal-appearing white matter (NAWM) into WMH remains unknown. We examined whether and when pro...

journal_title：Stroke

authors： van Leijsen EMC,Bergkamp MI,van Uden IWM,Ghafoorian M,van der Holst HM,Norris DG,Platel B,Tuladhar AM,de Leeuw FE

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patient and radiological characteristics of intracerebral hemorrhage (ICH), surgical treatment, and outcome after ICH are interrelated. Our purpose was to define whether these characteristics or surgical treatment correlate with mortality among young adults. METHODS:We retrospectively reviewed c...

journal_title：Stroke

authors： Koivunen RJ,Satopää J,Haapaniemi E,Strbian D,Meretoja A,Mustanoja S,Silvennoinen H,Salonen O,Niemelä M,Tatlisumak T,Putaala J

更新日期：2014-08-01 00:00:00

abstract：:Background and Purpose- Emergency medical services (EMSs) are critical for early treatment of patients with ischemic stroke, yet data on EMS utilization and its association with timely treatment in China are still limited. Methods- We examined data from the Chinese Stroke Center Alliance for patients with ischemic str...

journal_title：Stroke

authors： Gu HQ,Rao ZZ,Yang X,Wang CJ,Zhao XQ,Wang YL,Liu LP,Wang CY,Liu C,Li H,Li ZX,Xiao RP,Wang YJ,Chinese Stroke Center Alliance Investigators.

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Thrombolytic Therapy in Acute Ischemic Stroke Study, which started in August of 1991, was designed to assess the efficacy and safety of intravenous rtPA (alteplase) in patients with acute (0 to 6 hours) ischemic stroke. In October 1993 enrollment was halted because of Safety Committee (DMSB) ...

journal_title：Stroke

authors： Clark WM,Albers GW,Madden KP,Hamilton S

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is debate regarding the approach for analysis of modified Rankin scale scores, the most common functional outcome scale used in acute stroke trials. METHODS:We propose to use tests to assess treatment differences addressing the metric, "if a patient is chosen at random from each treatment ...

journal_title：Stroke

authors： Howard G,Waller JL,Voeks JH,Howard VJ,Jauch EC,Lees KR,Nichols FT,Rahlfs VW,Hess DC

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accumulating evidence indicates that inflammatory responses cause secondary injury after intracerebral hemorrhage (ICH). We recently demonstrated the involvement of toll-like receptor 4 (TLR4) signaling in these processes. The purpose of the current study was to investigate the protective effect ...

journal_title：Stroke

authors： Wang YC,Wang PF,Fang H,Chen J,Xiong XY,Yang QW

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) after stroke increases risk of hemorrhagic transformation, particularly in areas with blood-brain barrier leakage. Our aim was to characterize acute effects of rtPA administration on the integrity of microvascular barriers....

journal_title：Stroke

authors： Dijkhuizen RM,Asahi M,Wu O,Rosen BR,Lo EH

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To assess the association of lesion location and risk of aspiration and to establish predictors of transient versus extended risk of aspiration after supratentorial ischemic stroke. METHODS:Atlas-based localization analysis was performed in consecutive patients with MRI-proven first-time acute s...

journal_title：Stroke

authors： Galovic M,Leisi N,Müller M,Weber J,Abela E,Kägi G,Weder B

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to assess the costs and cost-effectiveness of intravenous thrombolysis treatment with alteplase (Actilyse) of acute ischemic stroke with 24-hour in-house neurology coverage and use of magnetic resonance imaging. METHODS:A health economic model was designed to calculate ...

journal_title：Stroke

authors： Ehlers L,Andersen G,Clausen LB,Bech M,Kjølby M

更新日期：2007-01-01 00:00:00

abstract：:Nineteen unanesthetized sheep were given Evans blue dye or radionuclide and then were incrementally bled into hemorrhagic shock (BP less than 50/25) by withdrawal of blood over a period of approximately one hour. Four sheep served as controls for histologic data. Static nuclide brain scans performed in 6 bled sheep d...

journal_title：Stroke

authors： Bronshvag MM

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial color-coded sonography is a new development in noninvasive cerebral vascular imaging. Reference data using this technique are described. METHODS:Blood velocities and pulsatility and resistance indices were determined in the anterior cerebral, middle cerebral, posterior cerebral, ver...

journal_title：Stroke

authors： Martin PJ,Evans DH,Naylor AR

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Spontaneous echo contrast (SEC) is thought to represent a risk factor for cardioembolic stroke. In vitro studies suggest that SEC results from interaction between red cells and fibrinogen. To better understand the relation between SEC and stroke and to investigate the in vivo genesis of SEC, we e...

journal_title：Stroke

authors： Briley DP,Giraud GD,Beamer NB,Spear EM,Grauer SE,Edwards JM,Clark WM,Sexton GJ,Coull BM

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of athersclerosis in the difference between the pathogenesis of large-vessel disease (LVD) and small-vessel disease (SVD) is a matter of debate. Common carotid artery intima-media thickness (CCA IMT) is a marker of atherosclerosis. Our aim was to compare CCA IMT between SVD and LVD patie...

journal_title：Stroke

authors： Pruissen DM,Gerritsen SA,Prinsen TJ,Dijk JM,Kappelle LJ,Algra A,SMART Study Group.

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke has been shown to alter autonomic function. The purpose of this study was to show the differential effects of stroke localization on autonomic function parameters assessed by heart rate variability (HRV). METHODS:To determine the differential effect of ischemic stroke localization on auto...

journal_title：Stroke

authors： Tokgözoglu SL,Batur MK,Topçuoglu MA,Saribas O,Kes S,Oto A

更新日期：1999-07-01 00:00:00

abstract：:The trends in age adjusted and age and sex specific mortality rates for the period 1968-1980 are compared for ischaemic heart disease and cerebrovascular disease. For both sexes and at all ages over 45 the mortality rates for cerebrovascular disease have fallen significantly. However, the mortality rates for ischaemic...

journal_title：Stroke

authors： Haberman S,Capildeo R,Rose FC

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Montreal Cognitive Assessment (MoCA) and Addenbrooke's Cognitive Examination-Revised (ACE-R) are proposed as short cognitive tests for use after stroke, but there are few published validations against a neuropsychological battery. We studied the relationship between MoCA, ACE-R, Mini-Mental S...

journal_title：Stroke

authors： Pendlebury ST,Mariz J,Bull L,Mehta Z,Rothwell PM

更新日期：2012-02-01 00:00:00

abstract：:It remains uncertain whether platelet activation in ischemic stroke is contributory or secondary to brain ischemia. The efficacy of aspirin (ASA) in stroke prevention suggests that platelet activation contributes to the occurrence of stroke. On the other hand, platelet activation may be simply a generalized consequenc...

journal_title：Stroke

authors： Shah AB,Beamer N,Coull BM

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Shoulder pain is a common complication after stroke that can impede participation in rehabilitation and has been associated with poorer outcomes. Evidence-based treatments for hemiplegic shoulder pain are limited. Suprascapular nerve block (SSNB) is a safe and effective treatment of shoulder pain...

journal_title：Stroke

authors： Adey-Wakeling Z,Crotty M,Shanahan EM

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A variety of primary end points have been used in acute stroke trials. We focus on the modified Rankin Scale, a reliable and valid ordinal outcome measure that assesses disability on a 7-point scale. METHODS:We provide an abbreviated discussion of analytical methods for ordinal scales, and relat...

journal_title：Stroke

authors： Koziol JA,Feng AC

更新日期：2006-10-01 00:00:00