Toll-like receptor 4 antagonist attenuates intracerebral hemorrhage-induced brain injury.

abstract：BACKGROUND AND PURPOSE:Historically, the use of tissue plasminogen activator (tPA) thrombolysis in pregnancy has been regarded as relatively contraindicated. Underlying this stance has been the concern over the risk of bleeding complications in both mother and child. SUMMARY OF CASE:We report the successful use of int...

journal_title：Stroke

authors： Wiese KM,Talkad A,Mathews M,Wang D

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little is known about the clinical outcomes associated with posthemorrhage anticoagulation resumption for atrial fibrillation. This study had 2 objectives: first, to evaluate anticoagulation use after a first major bleed on warfarin or dabigatran and, second, to compare effectiveness and safety o...

journal_title：Stroke

authors： Hernandez I,Zhang Y,Brooks MM,Chin PK,Saba S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiology of subarachnoid hemorrhage (SAH) is poorly understood. Reduced lung function, expressed as low forced expiratory volume in 1 second (FEV(1)) and low forced vital capacity (FVC), is a predictor of cardiovascular disease, but whether reduced lung function is a risk factor for SAH is no...

journal_title：Stroke

authors： Söderholm M,Zia E,Hedblad B,Engström G

更新日期：2012-10-01 00:00:00

abstract：:The effect of respiration on the cerebrovascular response to elevated intracranial pressure (ICP) was studied in anesthetized dogs. Total and regional cerebral blood flows were measured using labelled microspheres. In spontaneously breathing dogs total and regional cerebral blood flows increased when cerebral perfusio...

journal_title：Stroke

authors： Malik AB,Krasney JA,Royce GJ

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Type 2 diabetes is associated with a high cardiovascular morbidity and mortality. Recent advances of intervention studies in type 2 diabetes with use of carotid intima-media thickness (CIMT) measurement as a surrogate end point may allow for better understanding of the undetermined process of ath...

journal_title：Stroke

authors： Yokoyama H,Katakami N,Yamasaki Y

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Many patients with acute basilar artery occlusion may require endotracheal intubation and mechanical ventilation. The circumstances and predictive value for outcome in these patients are not well documented. METHODS:We reviewed the medical records of 25 patients admitted into the intensive care ...

journal_title：Stroke

authors： Wijdicks EF,Scott JP

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hetereothermic mammals tolerate hypoxia during euthermy and torpor, and evidence suggests this tolerance may extend beyond hypoxia to cerebral ischemia. During hibernation, CA1 hippocampal neurons endure extreme fluctuations in cerebral blood flow during transitions into and out of torpor as well...

journal_title：Stroke

authors： Dave KR,Prado R,Raval AP,Drew KL,Perez-Pinzon MA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Analysis of quality of care for in-hospital stroke has not been previously performed at the national level. This study compares patient characteristics, process measures of quality, and outcomes for in-hospital strokes with those for community-onset strokes in a national cohort. METHODS:We perfo...

journal_title：Stroke

authors： Cumbler E,Wald H,Bhatt DL,Cox M,Xian Y,Reeves M,Smith EE,Schwamm L,Fonarow GC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Diffusion-weighted MRI (DWI) and perfusion-weighted MRI (PWI) are new techniques that can be used for the evaluation of acute ischemic stroke. However, their potential role in the management of patients treated with recombinant tissue plasminogen activator (rtPA) has yet to be determined. CASE DESCRIPTION:T...

journal_title：Stroke

authors： Lansberg MG,Tong DC,Norbash AM,Yenari MA,Moseley ME

更新日期：1999-03-01 00:00:00

abstract：:Coarctation of the aorta is an uncommon cause of cerebral hemorrhage in the full- or near-term infant. The clinical, radiologic, and neurologic findings of four infants with aortic coarctation and cerebral hemorrhage are presented. In all four infants, cerebral hemorrhage was associated with only moderate elevation of...

journal_title：Stroke

authors： Young RS,Liberthson RR,Zalneraitis EL

更新日期：1982-07-01 00:00:00

abstract：:This study was conducted to determine whether air distributed to the cerebral circulation alone could cause acute cardiovascular dysfunction and thus be a potential mechanism for sudden death following arterial air embolism. Cardiovascular measurements were made in anesthetized, ventilated cats during infusion of air ...

journal_title：Stroke

authors： Evans DE,Kobrine AI,Weathersby PK,Bradley ME

更新日期：1981-05-01 00:00:00

abstract：:Exposure of Mongolian gerbils to a 100% oxygen atmosphere after 15 minutes of global brain ischemia resulted in a marked increase in the production of pentane, an in vivo product of lipid peroxidation. Much less pentane production occurred in animals subjected to global brain ischemia then exposed to an air atmosphere...

journal_title：Stroke

authors： Mickel HS,Vaishnav YN,Kempski O,von Lubitz D,Weiss JF,Feuerstein G

更新日期：1987-03-01 00:00:00

abstract：:Weights of matching right and left middle or posterior cerebral arteries and their main branches from the same animal were compared 8-10 weeks after unilateral denervation by superior cervical ganglionectomy. When compared in pairs, the denervated arterial systems weighed significantly less (mean 85%) than their inner...

journal_title：Stroke

authors： Bevan RD,Tsuru H,Bevan JA

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several markers of poststroke cognitive impairment have been reported. The role of brain cortical volume remains uncertain. The aim of this study was to evaluate the influence of brain cortical volume on cognitive outcomes using a voxel-based morphometry approach in subjects without prestroke dem...

journal_title：Stroke

authors： Sagnier S,Catheline G,Dilharreguy B,Munsch F,Bigourdan A,Poli M,Debruxelles S,Olindo S,Renou P,Rouanet F,Dousset V,Tourdias T,Sibon I

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In an inner-London teaching hospital, a randomized trial of "conventional" care versus early discharge to community-based therapy found no significant differences in clinical outcomes between patient groups. This report examines the economic consequences of the alternative strategies. METHODS:On...

journal_title：Stroke

authors： Beech R,Rudd AG,Tilling K,Wolfe CD

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral infarction in sickle cell disease is associated with arterial narrowing or occlusions of intracranial arteries. Primary stroke prevention would be feasible if a noninvasive screening test could be developed to detect intracranial disease in patients before symptoms develop. METHODS:To d...

journal_title：Stroke

authors： Adams RJ,Nichols FT,Figueroa R,McKie V,Lott T

更新日期：1992-08-01 00:00:00

abstract：:During the 5-year period from 1980 to 1984, the incidence of subarachnoid hemorrhage due only to rupture of aneurysms was investigated in Izumo City, a small city with a population of 79,026. Additionally, to ascertain the relation of incidence to the size of the geographic area and/or population, a similar analysis w...

journal_title：Stroke

authors： Inagawa T,Ishikawa S,Aoki H,Takahashi M,Yoshimoto H

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to clarify whether mitral valve prolapse increases the subsequent risk of stroke. METHODS:A historical cohort study was conducted on 1079 residents of Olmsted County, Minnesota, who had an initial echocardiographic diagnosis of mitral valve prolapse between 1975 and...

journal_title：Stroke

authors： Orencia AJ,Petty GW,Khandheria BK,Annegers JF,Ballard DJ,Sicks JD,O'Fallon WM,Whisnant JP

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Desaturation during swallowing may help to identify aspiration in stroke patients. This study investigated pulse oximetry, bedside swallowing assessment (BSA), and videofluoroscopy as tests for detecting aspiration after stroke. METHODS:Swallowing was assessed in 189 stroke patients (mean+/-SD a...

journal_title：Stroke

authors： Ramsey DJ,Smithard DG,Kalra L

更新日期：2006-12-01 00:00:00

abstract：:The angiographic, clinical, and genetic characteristics of fibromuscular dysplasia (FMD) are reviewed in 37 patients (mean age 48 years) selected from a pool of 4000 angiograms of carotid or vertebral arteries. FMD was a neglected pathogenic factor in 28 patients with hemorrhagic or ischemic cerebral lesions. The aneu...

journal_title：Stroke

authors： Mettinger KL,Ericson K

更新日期：1982-01-01 00:00:00

abstract：:Visually apparent EEG changes associated with clamping the internal carotid artery appeared in 55 of 176 consecutive patients (31%) undergoing carotid endarterectomy without shunt. Attenuation of higher frequency activity was the most common change. Changes were moderate in 33 patients (19%) and major in 22 (12.5%). M...

journal_title：Stroke

authors： Blume WT,Ferguson GG,McNeill DK

更新日期：1986-09-01 00:00:00

abstract：:Clinical and pathologic observations have suggested analogies between the developing nervous system of ferrets (Mustela putorius furo) and those of more traditional animal models employed in stroke research. Experimental work has demonstrated advantages of the ferret as a model of visual development. We performed in v...

journal_title：Stroke

authors： Atkinson CS,Press GA,Lyden P,Katz B

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Monocytes may contribute to secondary injury after intracerebral hemorrhage (ICH). We tested the association of absolute monocyte count with 30-day ICH case fatality in a multiethnic cohort. METHODS:Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study is a prospective, multicenter,...

journal_title：Stroke

authors： Walsh KB,Sekar P,Langefeld CD,Moomaw CJ,Elkind MS,Boehme AK,James ML,Osborne J,Sheth KN,Woo D,Adeoye O

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Neonatal stroke is increasingly recognized with an estimated incidence of one in 4000 live births per year. Pathways involved in the pathophysiology of neonatal stroke are diverse and may include thrombosis and thrombolysis, vascular reactivity, and inflammation. METHODS:We compared frequencies ...

journal_title：Stroke

authors： Miller SP,Wu YW,Lee J,Lammer EJ,Iovannisci DM,Glidden DV,Bonifacio SL,Collins A,Shaw GM,Barkovich AJ,Ferriero DM

更新日期：2006-11-01 00:00:00

abstract：:The nature of alpha-adrenergic receptors in human cerebral arteries was characterized, and alteration of these receptors after subarachnoid hemorrhage was examined using a radioligand binding assay. Norepinephrine content of control arteries was also analyzed and compared with that of arteries after subarachnoid hemor...

journal_title：Stroke

authors： Tsukahara T,Taniguchi T,Miwa S,Shimohama S,Fujiwara M,Nishikawa M,Handa H

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some clinical models, like California ABCD and unified ABCD2 scores, are now available to predict the early risk of stroke after a TIA. Despite the transitivity of symptoms, DWI identified an area of acute brain ischemia in almost half of patients. It would be interesting to know how the presence...

journal_title：Stroke

authors： Purroy F,Begué R,Quílez A,Piñol-Ripoll G,Sanahuja J,Brieva L,Setó E,Gil MI

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Treatment of stroke patients in specialized stroke units has become more frequent, yet the effect of this treatment has not been determined. METHODS:In a community-based, prospective, and consecutive study of 1241 unselected acute stroke patients, we compared outcome of stroke treatment between ...

journal_title：Stroke

authors： Jørgensen HS,Nakayama H,Raaschou HO,Larsen K,Hübbe P,Olsen TS

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent evidence suggests that physiological changes in the concentration of endogenous estrogens may influence stroke outcome. The purpose of this study was to determine a menstrual cycle-related profile of blood flow through the carotid arteries and its correlation with estrogen concentration. ...

journal_title：Stroke

authors： Krejza J,Mariak Z,Huba M,Wolczynski S,Lewko J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of our study was to compare outcome and its determinants in familial subarachnoid hemorrhage and in sporadic subarachnoid hemorrhage in a large and well-documented patient population. METHODS:Patients with aneurysmal subarachnoid hemorrhage (SAH) treated at the Department of Neurosurgery...

journal_title：Stroke

authors： Ronkainen A,Niskanen M,Piironen R,Hernesniemi J

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acute cerebral ischemia is frequently associated with headache. It is unknown whether concomitant headache reflects a partly different pathogenesis, and thus, may influence long-term prognosis after stroke. Here, we compared the long-term risk of recurrent vascular events in patients in whom a tr...

journal_title：Stroke

authors： Maino A,Algra A,Koudstaal PJ,van Zwet EW,Ferrari MD,Wermer MJ,LiLAC Study Group.

更新日期：2013-09-01 00:00:00