Anticoagulation Use and Clinical Outcomes After Major Bleeding on Dabigatran or Warfarin in Atrial Fibrillation.

abstract：BACKGROUND AND PURPOSE:Stroke incidence and mortality are declining rapidly in developed countries. Little data on ethnic-specific stroke recurrence trends exist. Fourteen-year stroke recurrence trend estimates were evaluated in Mexican Americans and non-Hispanic whites in a population-based study. METHODS:Recurrent s...

journal_title：Stroke

authors： Sozener CB,Lisabeth LD,Shafie-Khorassani F,Kim S,Zahuranec DB,Brown DL,Skolarus LE,Burke JF,Kerber KA,Meurer WJ,Case E,Morgenstern LB

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In acute ischemic stroke, the hypoperfused but viable tissue is the main therapeutic target. In clinical routine, time-to-peak (TTP) maps are frequently used to estimate the hemodynamic compromise and to calculate the mismatch volume. We evaluated the accuracy of TTP maps to identify penumbral fl...

journal_title：Stroke

authors： Sobesky J,Zaro Weber O,Lehnhardt FG,Hesselmann V,Thiel A,Dohmen C,Jacobs A,Neveling M,Heiss WD

更新日期：2004-12-01 00:00:00

abstract：:The cardiac conditions most commonly associated with cerebral embolism are rheumatic heart disease (RHD), atherosclerotic heart disease (myocardial infarction and atrial arrhythmias) and other kinds of nonvalvular atrial fibillation (AF). The natural history of cerebral embolism from these cardiac sources is reviewed....

journal_title：Stroke

authors： Easton JD,Sherman DG

更新日期：1980-09-01 00:00:00

abstract：:Background and Purpose- High-resolution vessel wall magnetic resonance imaging is a promising technique for assessing wall structures of unruptured intracranial aneurysms (UIAs). However, the relationship between aneurysmal high-resolution vessel wall magnetic resonance imaging features and their histopathologic mecha...

journal_title：Stroke

authors： Quan K,Song J,Yang Z,Wang D,An Q,Huang L,Liu P,Li P,Tian Y,Zhou L,Zhu W

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to define the influence of feeding mean arterial pressure (FMAP) in conjunction with other morphological or clinical risk factors in determining the probability of hemorrhagic presentation in patients with cerebral arteriovenous malformations (AVMs). METHODS:Clinical and angiograp...

journal_title：Stroke

authors： Duong DH,Young WL,Vang MC,Sciacca RR,Mast H,Koennecke HC,Hartmann A,Joshi S,Mohr JP,Pile-Spellman J

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little is known about how regions vary in their use of thrombolysis (intravenous tissue-type plasminogen activator and intra-arterial treatment) for acute stroke. We sought to determine regional variation in thrombolysis treatment and investigate the extent to which regional variation is accounte...

journal_title：Stroke

authors： Skolarus LE,Meurer WJ,Shanmugasundaram K,Adelman EE,Scott PA,Burke JF

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Short-term elevations in fine particulate matter air pollution (PM2.5) are associated with increased risk of acute cerebrovascular events. Evidence from the peripheral circulation suggests that vascular dysfunction may be a central mechanism. However, the effects of PM2.5 on cerebrovascular funct...

journal_title：Stroke

authors： Wellenius GA,Boyle LD,Wilker EH,Sorond FA,Coull BA,Koutrakis P,Mittleman MA,Lipsitz LA

更新日期：2013-06-01 00:00:00

abstract：:We examined the 21-aminosteroid U74006F, a potent inhibitor of lipid peroxidation, for potential neuroprotective effects in a canine model of complete cerebral ischemia. Two 1.5-mg/kg boluses were administered to six dogs, the first bolus 15 minutes prior to a 12-minute episode of complete cerebral ischemia and the se...

journal_title：Stroke

authors： Perkins WJ,Milde LN,Milde JH,Michenfelder JD

更新日期：1991-07-01 00:00:00

abstract：:Background and Purpose- We aimed to define the neuroimaging determinants of poststroke cognitive performance and their relative contributions among a spectrum of magnetic resonance imaging markers, including lesion burden and strategic locations. Methods- We prospectively included patients with stroke from the GRECogV...

journal_title：Stroke

authors： Puy L,Barbay M,Roussel M,Canaple S,Lamy C,Arnoux A,Leclercq C,Mas JL,Tasseel-Ponche S,Constans JM,Godefroy O,GRECogVASC Study Group.

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic injury triggers multiple pathological responses in the brain tissue, including spreading depolarizations across the cerebral cortex (cortical spreading depolarizations [CSD]). Microglia have been recently shown to play a significant role in the propagation of CSD. However, the intracellu...

journal_title：Stroke

authors： Liu L,Kearns KN,Eli I,Sharifi KA,Soldozy S,Carlson EW,Scott KW,Sluzewski MF,Acton ST,Stauderman KA,Kalani MYS,Park M,Tvrdik P

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Diffusion-weighted MRI can demonstrate decreases of the apparent diffusion coefficient (ADC) of brain tissue water shortly after the onset of ischemia. To further elucidate underlying mechanisms, this study extended diffusion assessment to intracellular metabolites in rat brain in vivo before, du...

journal_title：Stroke

authors： Wick M,Nagatomo Y,Prielmeier F,Frahm J

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The mechanisms underlying frontal lobe dysfunction in moyamoya disease (MMD) are unknown. We aimed to determine whether chronic ischemia induces subtle microstructural brain changes in adult MMD and evaluated the association of changes with neuropsychological performance. METHODS:MRI, including ...

journal_title：Stroke

authors： Kazumata K,Tha KK,Narita H,Kusumi I,Shichinohe H,Ito M,Nakayama N,Houkin K

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Epidemiological data about stroke are scarce in low- and middle-income Latin-American countries. We investigated annual incidence of first-ever stroke and transient ischemic attack (TIA) and 30-day case-fatality rates in a population-based setting in Tandil, Argentina. METHODS:We prospectively i...

journal_title：Stroke

authors： Bahit MC,Coppola ML,Riccio PM,Cipriano LE,Roth GA,Lopes RD,Feigin VL,Borrego Guerrero B,De Martino M,Díaz A,Ferrante D,Funaro F,Lavados P,Lewin ML,López DH,Macarrone P,Marciello R,Marino D,Martens C,Martínez P,Odr

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke leads to a reduction in bone mineral density, altered calcium homeostasis, and an increase in hip fractures. Vitamin D deficiency is well documented in long-term stroke survivors and is associated with post-stroke hip fractures. Less is known regarding levels in acute stroke. METHODS:We c...

journal_title：Stroke

authors： Poole KE,Loveridge N,Barker PJ,Halsall DJ,Rose C,Reeve J,Warburton EA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies of the cerebroprotective effects of selective brain cooling have failed to show amelioration of ischemic injury in the cerebral cortex. This study was designed to test the hypothesis that mild-to-moderate selective brain cooling initiated after the onset of global brain ischemia in rats p...

journal_title：Stroke

authors： Kuluz JW,Gregory GA,Yu AC,Chang Y

更新日期：1992-12-01 00:00:00

abstract：:A 25-year-old black man with sarcoidosis presented with transient ischemic attacks followed by sudden, persistent right hemiparesis. He gave a history of recent, recurrent lower motor neuron facial palsy. Computed tomography demonstrated an infarct in the left internal capsule. Chest x-ray film showed bilateral hilar ...

journal_title：Stroke

authors： Brown MM,Thompson AJ,Wedzicha JA,Swash M

更新日期：1989-03-01 00:00:00

abstract：:Background and Purpose- Cerebral small vessel disease (SVD) is a major cause of stroke and dementia, but underlying disease mechanisms are still largely unknown, partly because of the difficulty in assessing small vessel function in vivo. We developed a method to measure blood flow velocity pulsatility in perforating ...

journal_title：Stroke

authors： Geurts LJ,Zwanenburg JJM,Klijn CJM,Luijten PR,Biessels GJ

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND AND PURPOSE:Current guidelines recommend against routine auscultation of carotid arteries, believing that carotid bruits are poor predictors of either underlying carotid stenosis or stroke risk in asymptomatic patients. We investigated whether the presence of a carotid bruit is associated with increased risk...

journal_title：Stroke

authors： Pickett CA,Jackson JL,Hemann BA,Atwood JE

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Venous thromboembolism and ischemic stroke are associated with unfavorable fibrin clot structure and function. We hypothesized that denser fibrin networks displaying impaired lysability characterize patients with cerebral venous sinus thrombosis (CVST). METHODS:We assessed plasma fibrin clot pro...

journal_title：Stroke

authors： Siudut J,Świat M,Undas A

更新日期：2015-09-01 00:00:00

abstract：:Background and Purpose- Given inconclusive studies, it is debated whether clinical and imaging characteristics, as well as functional outcome, differ among patients with intracerebral hemorrhage (ICH) related to vitamin K antagonists (VKA) versus non-vitamin K antagonist (NOAC)-related ICH. Notably, clinical character...

journal_title：Stroke

authors： Gerner ST,Kuramatsu JB,Sembill JA,Sprügel MI,Hagen M,Knappe RU,Endres M,Haeusler KG,Sobesky J,Schurig J,Zweynert S,Bauer M,Vajkoczy P,Ringleb PA,Purrucker JC,Rizos T,Volkmann J,Müllges W,Kraft P,Schubert AL,Erbgut

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid artery intima-media thickness (IMT) is a marker of cardiovascular disease associated with incident stroke. We studied whether IMT rate of change is associated with stroke. METHODS:We studied 5028 participants of the Multi-Ethnic Study of Atherosclerosis (MESA) comprising white, Chinese, ...

journal_title：Stroke

authors： Polak JF,Pencina MJ,O'Leary DH,D'Agostino RB

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Antiplatelet therapy is currently one of the methods for preventing transient ischemic attacks and cerebral thrombosis. Because antiplatelet agents are generally administered on a long-term basis, patient compliance is an important factor. The purpose of this study was to determine the compliance...

journal_title：Stroke

authors： Komiya T,Kudo M,Urabe T,Mizuno Y

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Large pulse pressure associates with atherosclerosis, but it is unclear if it contributes to the development of atherosclerosis or if atherosclerosis leads to pulse pressure widening. We examined whether exposure to large pulse pressure in childhood predicts carotid artery intima-media thickness ...

journal_title：Stroke

authors： Raitakari OT,Juonala M,Taittonen L,Jula A,Laitinen T,Kähönen M,Viikari JS

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study is to estimate the risk of ischemic stroke during a 3-year follow-up period after a tuberculosis diagnosis using a nationwide, population-based study and a retrospective cohort design. METHOD:The study cohort comprised 2283 patients who had received treatment for tuberculos...

journal_title：Stroke

authors： Sheu JJ,Chiou HY,Kang JH,Chen YH,Lin HC

更新日期：2010-02-01 00:00:00

abstract：:Various studies indicate that after a latent interval, a progressive focal deterioration of microvascular perfusion can develop in zones of acute damage to the central nervous system (CNS). In order to obtain reliable information concerning the possibility of platelet participation in this phenomenon, platelet deposit...

journal_title：Stroke

authors： Obrenovitch TP,Hallenbeck JM

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Homocysteine has been linked to increased risk of ischemic stroke and other cardiovascular events. Matrix degradation and inflammation play an important role in these disorders, and we have demonstrated increased levels of matrix-degrading enzymes and inflammatory cytokines in hyperhomocysteinemi...

journal_title：Stroke

authors： Nenseter MS,Ueland T,Retterstøl K,Strøm E,Mørkrid L,Landaas S,Ose L,Aukrust P,Holven KB

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animals, drugs that increase brain amine concentrations influence the rate and degree of recovery from cortical lesions. It is therefore conceivable that antidepressants may influence outcome after ischemic brain injury in humans. We evaluated the effects of the norepinephrine reuptake blocker...

journal_title：Stroke

authors： Dam M,Tonin P,De Boni A,Pizzolato G,Casson S,Ermani M,Freo U,Piron L,Battistin L

更新日期：1996-07-01 00:00:00

abstract：:Background and Purpose- Endovascular thrombectomy (ET) door-to-puncture time (DTPT) is a modifiable metric. One of the most important, yet time-consuming steps, is documentation of large vessel occlusion by computed tomography angiography (CTA). We hypothesized that obtaining CTA on board a Mobile Stroke Unit and dire...

journal_title：Stroke

authors： Czap AL,Singh N,Bowry R,Jagolino-Cole A,Parker SA,Phan K,Wang M,Sheth SA,Rajan SS,Yamal JM,Grotta JC

更新日期：2020-05-01 00:00:00

abstract：:Clinicopathologic correlations were reviewed in 100 cases of recent cerebral infarctions in the internal carotid artery distribution. The most frequent cause of death was transtentorial herniation, followed in frequency by pneumonia, cardiac causes, and pulmonary embolism. Thirty-six percent of all patients and 47% of...

journal_title：Stroke

authors： Bounds JV,Wiebers DO,Whisnant JP,Okazaki H

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:To judge the efficacy of new, putative stroke therapies, we need a method to measure neurological deficit accurately in groups of patients before and after treatment. No single measurement technique has yet proven to be universally acceptable, but one approach is the use of rating instruments that summarize ...

journal_title：Stroke

authors： Lyden PD,Lau GT

更新日期：1991-11-01 00:00:00