Outcome in patients with acute basilar artery occlusion requiring mechanical ventilation.

Abstract:

BACKGROUND AND PURPOSE:Many patients with acute basilar artery occlusion may require endotracheal intubation and mechanical ventilation. The circumstances and predictive value for outcome in these patients are not well documented. METHODS:We reviewed the medical records of 25 patients admitted into the intensive care unit with a clinical diagnosis of acute basilar artery occlusion and need for mechanical ventilation. The medical records were reviewed for clinical features, breathing patterns, mode of mechanical ventilation, ability to wean from the ventilator, and neurological outcome. RESULTS:Apneic episodes resulted in endotracheal intubation in 8 patients. In the remaining 17 patients, intubation was needed for airway protection. Seven of 8 patients presenting with apneic episodes lost all brain stem reflexes. All 17 patients intubated for airway protection could be successfully weaned to a T-tube circuit. Outcome was generally poor and 22 patients died, of whom 7 died of early systemic complications. Only 3 of 25 patients, all with locked-in syndrome, survived. CONCLUSIONS:Mortality is high in patients who require mechanical ventilation after acute basilar artery occlusion. No neurological improvement beyond a locked-in syndrome occurred in survivors. Recurrent apnea appears to predict further progression to brain stem death.

journal_name

Stroke

journal_title

Stroke

authors

Wijdicks EF,Scott JP

doi

10.1161/01.str.27.8.1301

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

1301-3

issue

8

eissn

0039-2499

issn

1524-4628

journal_volume

27

pub_type

杂志文章

相关文献

STROKE文献大全
  • Racial disparities in stroke risk factors: the impact of socioeconomic status.

    abstract:BACKGROUND AND PURPOSE:In the US, blacks have a higher incidence of stroke and more severe strokes than whites. Our objective was to determine if differences in income, education, and insurance, as well as differences in the prevalence of stroke risk factors, accounted for the association between ethnicity and stroke. ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000170991.63594.b6

    authors: Bravata DM,Wells CK,Gulanski B,Kernan WN,Brass LM,Long J,Concato J

    更新日期:2005-07-01 00:00:00

  • Age dependence of risk factors for stroke and death in young patients with atrial fibrillation: a nationwide study.

    abstract:BACKGROUND AND PURPOSE:The risk of stroke and death in patients with atrial fibrillation is strongly associated with age and concomitant comorbidities. The aim of this study was to examine the age dependence of risk factors for stroke and mortality in young patients with atrial fibrillation. METHODS:This study is a po...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.114.004903

    authors: Melgaard L,Rasmussen LH,Skjøth F,Lip GY,Larsen TB

    更新日期:2014-05-01 00:00:00

  • Adiponectin and risk of stroke: prospective study and meta-analysis.

    abstract:BACKGROUND AND PURPOSE:The favorable cardiovascular effects attributed to adiponectin may lower risk of stroke. We investigated this in a prospective study and meta-analysis. METHODS:A case-cohort study nested within the Potsdam cohort of the European Prospective Investigation into Cancer was performed, with 170 incid...

    journal_title:Stroke

    pub_type: 杂志文章,meta分析

    doi:10.1161/STROKEAHA.113.001851

    authors: Arregui M,Buijsse B,Fritsche A,di Giuseppe R,Schulze MB,Westphal S,Isermann B,Boeing H,Weikert C

    更新日期:2014-01-01 00:00:00

  • Age-related changes in release of endothelium-derived relaxing factor from the carotid artery.

    abstract:BACKGROUND AND PURPOSE:The goal of this study was to determine whether release of endothelium-derived relaxing factor (EDRF) from carotid artery in response to acetylcholine is altered by aging. METHODS:Responses were examined in arteries from Wistar rats 6 to 8 months old (young rats), 24 to 26 months old (old rats),...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.12.2457

    authors: Paternò R,Faraci FM,Heistad DD

    更新日期:1994-12-01 00:00:00

  • In situ beta-irradiation of a brain arteriovenous malformation model.

    abstract:BACKGROUND AND PURPOSE:The treatment of large brain arteriovenous malformations (BAVMs) is challenging, and embolization alone is seldom curative. The study goal is to enhance the efficacy of arteriovenous malformation embolization by adding a beta-emitting isotope to the embolic agent. METHODS:The pig rete mirabile w...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000185673.73381.4c

    authors: Roy D,Soucy JP,Hartman NG,Janicki C,Weill A,Guilbert F,Papineau K,Raymond J

    更新日期:2005-11-01 00:00:00

  • Blood pressure control and risk of stroke: a population-based prospective cohort study.

    abstract:BACKGROUND AND PURPOSE:Adequate control of blood pressure (BP) is a cornerstone in stroke prevention. This study explored the risk of stroke in relation to the quality of BP control in a population-based cohort and whether control of hypertension was related to background characteristics of patients. METHODS:A total o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000158925.12740.87

    authors: Li C,Engström G,Hedblad B,Berglund G,Janzon L

    更新日期:2005-04-01 00:00:00

  • Validity of self-reported stroke : The Tromso Study.

    abstract:BACKGROUND AND PURPOSE:The aim of this study was to validate the diagnosis of self-reported stroke. METHODS:During 1994-1995, 27 159 people attended a population health survey in the community of Tromso, Norway, a response rate of 77%. A total of 418 attenders reported a history of stroke. In 1997, all individuals wit...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.31.7.1602

    authors: Engstad T,Bonaa KH,Viitanen M

    更新日期:2000-07-01 00:00:00

  • The Virtual International Stroke Trials Archive.

    abstract:BACKGROUND AND PURPOSE:Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal. The unsuccessful outcome of several research programs highlights the need for reliable data on which to plan future clinical trials. The Virtual Internat...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.106.473579

    authors: Ali M,Bath PM,Curram J,Davis SM,Diener HC,Donnan GA,Fisher M,Gregson BA,Grotta J,Hacke W,Hennerici MG,Hommel M,Kaste M,Marler JR,Sacco RL,Teal P,Wahlgren NG,Warach S,Weir CJ,Lees KR

    更新日期:2007-06-01 00:00:00

  • Fibromuscular dysplasia and the brain. I. Observations on angiographic, clinical and genetic characteristics.

    abstract::The angiographic, clinical, and genetic characteristics of fibromuscular dysplasia (FMD) are reviewed in 37 patients (mean age 48 years) selected from a pool of 4000 angiograms of carotid or vertebral arteries. FMD was a neglected pathogenic factor in 28 patients with hemorrhagic or ischemic cerebral lesions. The aneu...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.13.1.46

    authors: Mettinger KL,Ericson K

    更新日期:1982-01-01 00:00:00

  • Impaired dynamic cerebral autoregulation in carotid artery stenosis.

    abstract:BACKGROUND AND PURPOSE:If it could be determined whether cerebral blood flow can be maintained (autoregulated) during transient falls in arterial blood pressure, we might be able to identify patients with carotid stenosis who are at risk of stroke. However, conventional methods of determining autoregulation in such pat...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.28.7.1340

    authors: White RP,Markus HS

    更新日期:1997-07-01 00:00:00

  • Effect of therapy on platelet activating factor-induced aggregation in acute stroke.

    abstract::Platelet activating factor, a potent inducer of in vivo platelet activation and thrombosis, has been shown to be excessively active in acute ischemic stroke patients. Therefore, we studied the effect of aspirin/dipyridamole therapy in inhibiting platelet activating factor-induced platelet activation in acute ischemic ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.20.5.609

    authors: Joseph R,Welch KM,D'Andrea G

    更新日期:1989-05-01 00:00:00

  • Predictors of early arterial reocclusion after tissue plasminogen activator-induced recanalization in acute ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:We aimed to determine clinical and hemodynamic predictors of early reocclusion (RO) in stroke patients treated with intravenous tissue plasminogen activator (tPA). METHODS:We studied 142 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with intravenous...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000170711.43405.81

    authors: Rubiera M,Alvarez-Sabín J,Ribo M,Montaner J,Santamarina E,Arenillas JF,Huertas R,Delgado P,Purroy F,Molina CA

    更新日期:2005-07-01 00:00:00

  • Reduction and restoration of mitochondrial dna content after focal cerebral ischemia/reperfusion.

    abstract:BACKGROUND AND PURPOSE:Oxidative damage of mitochondrial DNA (mtDNA) in the ischemic brain is expected after ischemia/reperfusion injury. A recent study demonstrated limited patterns of mtDNA deletion in the brain after ischemia/reperfusion. We studied the ischemia/reperfusion-induced global changes of mtDNA integrity ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/hs1001.097099

    authors: Chen H,Hu CJ,He YY,Yang DI,Xu J,Hsu CY

    更新日期:2001-10-01 00:00:00

  • Declining Admission and Mortality Rates for Subarachnoid Hemorrhage in Canada Between 2004 and 2015.

    abstract::Background and Purpose- The purpose of this study was to assess recent trends in the admission and mortality rates for subarachnoid hemorrhage in Canada. Methods- This retrospective cross-sectional study was based on data retrieved from the Canadian Institute for Health Information for all patients diagnosed with suba...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.022332

    authors: Chan V,Lindsay P,McQuiggan J,Zagorski B,Hill MD,O'Kelly C

    更新日期:2018-11-21 00:00:00

  • White Matter Hyperintensity-Adjusted Critical Infarct Thresholds to Predict a Favorable 90-Day Outcome.

    abstract:BACKGROUND AND PURPOSE:There is increasing interest in defining stroke lesion volume thresholds to predict poststroke outcome. However, there is a paucity of data on factors that impact the association between critical infarct thresholds volume and outcome. We sought to determine whether lesion thresholds best predicti...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.013982

    authors: Patti J,Helenius J,Puri AS,Henninger N

    更新日期:2016-10-01 00:00:00

  • Early intravenous thrombolysis for acute ischemic stroke in a community-based approach.

    abstract:BACKGROUND AND PURPOSE:Controlled multicenter studies have demonstrated the efficacy of systemic recombinant tissue-type plasminogen activator (rtPA) treatment in selected cases of acute ischemic stroke. The feasibility of this therapeutic option in clinical practice was assessed in a community-based approach. METHODS...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1161/01.str.29.8.1544

    authors: Grond M,Stenzel C,Schmülling S,Rudolf J,Neveling M,Lechleuthner A,Schneweis S,Heiss WD

    更新日期:1998-08-01 00:00:00

  • Blood flow measurements and the "look through" artifact in focal cerebral ischemia.

    abstract::Regional cerebral blood flow (CBF) was measured (intra-arterial injections of 133Xe) and electroencephalograms (EEG) were recorded periodically before, for two hours during, and for one and one-fourth hours after middle cerebral artery (MCA) occlusion in 20 squirrel monkeys (Saimiri sciureus). A CBF-Paco2 response cur...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.6.2.121

    authors: Donley RF,Sundt TM,Anderson RE,Sharbrough FW

    更新日期:1975-03-01 00:00:00

  • Distinct Short-Term Outcomes in Patients With Mild Versus Rapidly Improving Stroke Not Treated With Thrombolytics.

    abstract:BACKGROUND AND PURPOSE:Mild stroke (MS) and rapidly improving stroke (RIS) symptoms are common stroke presentations. Our objective is to describe the short-term outcomes in this population. METHODS:A retrospective analysis of patients with ischemic stroke in the Get With The Guidelines-Stroke registry who arrived ≤4.5...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.011528

    authors: Romano JG,Smith EE,Liang L,Gardener H,Campo-Bustillo I,Khatri P,Bhatt DL,Fonarow GC,Sacco RL,Schwamm LH

    更新日期:2016-05-01 00:00:00

  • Facilitating postischemic reduction of cerebral lactate in rats.

    abstract:BACKGROUND AND PURPOSE:Dichloroacetate facilitates a decrease in brain lactate during reperfusion after incomplete ischemia. This study examined the possible activation of pyruvate dehydrogenase enzyme by dichloroacetate to explain this effect. Because the duration of ischemia and hyperglycemia exacerbate ischemic brai...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.23.8.1145

    authors: Dimlich RV,Nielsen MM

    更新日期:1992-08-01 00:00:00

  • Studies on cerebral blood flow and oxygen metabolism in patients with established cerebral infarcts undergoing omental transposition.

    abstract::Regional cerebral blood flow, blood volume, fractional oxygen extraction, and oxygen consumption were measured by positron emission tomography in 4 stroke patients prior to and 6 months following omental transposition surgery. Preoperatively, 3 patients showed the typical picture of established infarction with a match...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.18.1.46

    authors: Herold S,Frackowiak RS,Neil-Dwyer G

    更新日期:1987-01-01 00:00:00

  • Asymptomatic coronary artery disease in patients with stroke. Prevalence, prognosis, diagnosis, and treatment.

    abstract::The frequency of angiographically defined asymptomatic CAD in patients with carotid disease is 40%. Although the prognosis of patients with asymptomatic 1-vessel or 2-vessel CAD is good (annual cardiac mortality rate less than 2%), the prognosis of asymptomatic 3-vessel disease or left main CAD is substantially less f...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.str.23.3.433

    authors: Chimowitz MI,Mancini GB

    更新日期:1992-03-01 00:00:00

  • VEGF receptor-2 variants are associated with susceptibility to stroke and recurrence.

    abstract:BACKGROUND AND PURPOSE:Dysregulation of vessel wall formation, growth, and maintenance may confer susceptibility of stroke. METHODS:We tested the hypothesis that variants in 2 genes encoding vascular endothelial growth factor and vascular endothelial growth factor receptor-2 are associated with susceptibility to strok...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究

    doi:10.1161/STROKEAHA.109.554394

    authors: Zhang W,Sun K,Zhen Y,Wang D,Wang Y,Chen J,Xu J,Hu FB,Hui R

    更新日期:2009-08-01 00:00:00

  • Incidence of aneurysmal subarachnoid hemorrhage in Shimokita, Japan, from 1989 to 1998.

    abstract:BACKGROUND AND PURPOSE:The incidence of subarachnoid hemorrhage (SAH) has been investigated in many studies. A recent study in Izumo, Japan, indicates that the incidence of SAH is as high as that in Finland. The purpose of this study was to confirm the high incidence of SAH in Japan. METHODS:The incidence rate of SAH ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/hs0102.101891

    authors: Ohkuma H,Fujita S,Suzuki S

    更新日期:2002-01-01 00:00:00

  • Axonal remodeling of the corticospinal tract in the spinal cord contributes to voluntary motor recovery after stroke in adult mice.

    abstract:BACKGROUND AND PURPOSE:We sought to demonstrate the contribution of axonal remodeling of the corticospinal tract (CST) in the spinal cord to functional outcome after stroke. METHODS:Bilateral pyramidotomy (BPT) or sham-BPT was performed in mice with transgenic yellow fluorescent protein labeling in the CST subjected t...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.113.001162

    authors: Liu Z,Chopp M,Ding X,Cui Y,Li Y

    更新日期:2013-07-01 00:00:00

  • Intra-arterial thrombolytic therapy for acute basilar occlusion: pro.

    abstract::Acute thromboembolic occlusion of the basilar artery accounts for 6% to 10% of large-vessel stroke in humans. Because of the brain region supplied by this artery, the case fatality rate is the highest for all ischemic stroke subtypes, ranging from 40% to 86%. Patients who undergo successful recanalization of the basil...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.STR.0000247897.33267.42

    authors: Smith WS

    更新日期:2007-02-01 00:00:00

  • Cathepsin and calpain inhibitor E64d attenuates matrix metalloproteinase-9 activity after focal cerebral ischemia in rats.

    abstract:BACKGROUND AND PURPOSE:Matrix metalloproteinases (MMPs) and cysteine proteases (calpain and cathepsin B) play an important role in cell death and are upregulated after focal cerebral ischemia. Because there is a significant interaction between MMP-9 with calpain and cathepsin B, we investigated the role of E64d (a calp...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000227259.15506.24

    authors: Tsubokawa T,Solaroglu I,Yatsushige H,Cahill J,Yata K,Zhang JH

    更新日期:2006-07-01 00:00:00

  • Invasive Monitoring of Intracranial Pressure After Decompressive Craniectomy in Malignant Stroke.

    abstract:BACKGROUND AND PURPOSE:The role of decompressive hemicraniectomy (DC) in malignant cerebral infarction (MCI) has clearly been established, but little is known about the course of intracranial pressure (ICP) in patients undergoing this surgical measure. In this study, we investigated the role of invasive ICP monitoring ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.032390

    authors: Hernández-Durán S,Meinen L,Rohde V,von der Brelie C

    更新日期:2021-01-01 00:00:00

  • Associations of inflammatory and hemostatic variables with the risk of recurrent stroke.

    abstract:BACKGROUND AND PURPOSE:Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these varia...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1161/01.STR.0000181754.38408.4c

    authors: Woodward M,Lowe GD,Campbell DJ,Colman S,Rumley A,Chalmers J,Neal BC,Patel A,Jenkins AJ,Kemp BE,MacMahon SW

    更新日期:2005-10-01 00:00:00

  • Pseudocontinuous arterial spin labeling quantifies relative cerebral blood flow in acute stroke.

    abstract:BACKGROUND AND PURPOSE:The aim of this study was to test whether arterial spin labeling (ASL) can detect significant differences in relative cerebral blood flow (rCBF) in the core, mismatch, and reverse-mismatch regions, and whether rCBF values measured by ASL in those areas differ from values obtained using dynamic su...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.111.635979

    authors: Hernandez DA,Bokkers RP,Mirasol RV,Luby M,Henning EC,Merino JG,Warach S,Latour LL

    更新日期:2012-03-01 00:00:00

  • Intakes of potassium, magnesium, and calcium and risk of stroke.

    abstract:BACKGROUND AND PURPOSE:We aimed to investigate the associations of dietary and total potassium, magnesium, and calcium intakes with stroke occurrence. METHODS:A prospective cohort study was conducted among 36 094 participants aged 21 to 70 years. Dietary intake was assessed with a food frequency questionnaire. RESULT...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.113.004032

    authors: Sluijs I,Czernichow S,Beulens JW,Boer JM,van der Schouw YT,Verschuren WM,Grobbee DE

    更新日期:2014-04-01 00:00:00