Evidence for platelet-activating factor as a novel mediator in experimental stroke in rabbits.

abstract：BACKGROUND AND PURPOSE:The first goal of this study was to determine the effect of glutamate on permeability and reactivity of the cerebral microcirculation. The second goal of this study was to determine a possible role for nitric oxide in the effects of glutamate on the cerebral microcirculation. METHODS:We examined...

journal_title：Stroke

authors： Mayhan WG,Didion SP

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The diagnosis of intracranial atherosclerosis requires availability of appropriate imaging techniques. The objective was to evaluate the proportion of European hospitals where imaging techniques necessary to detect intracranial atherosclerosis are available. Method- We randomly selected 886 hospi...

journal_title：Stroke

authors： Balucani C,Leys D,Ringelstein EB,Kaste M,Hacke W,Executive Committee of the European Stroke Initiative.

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:beta-Blockers prevent vascular events in patients after myocardial infarction and lower blood pressure, the main risk factor for stroke. Hence, we assessed the effects of atenolol on the occurrence of death from vascular causes, stroke, or myocardial infarction and on blood pressure in patients a...

journal_title：Stroke

authors：

更新日期：1993-04-01 00:00:00

abstract：:In this retrospective analysis we report our treatment experience in 65 consecutive patients with clinical signs of severe brainstem ischemia with angiographically demonstrated thrombotic vertebrobasilar artery occlusions who received either local intra-arterial thrombolytic therapy (urokinase or streptokinase) (43 pa...

journal_title：Stroke

authors： Hacke W,Zeumer H,Ferbert A,Brückmann H,del Zoppo GJ

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lacunar syndromes correlate with a lacunar stroke on imaging in 50% to 60% of cases. Computed tomography perfusion (CTP) is becoming the preferred imaging modality for acute stroke triage. We aimed to estimate the sensitivity, specificity, and predictive values for noncontrast computed tomography...

journal_title：Stroke

authors： Garcia-Esperon C,Visser M,Churilov L,Miteff F,Bivard A,Lillicrap T,Levi CR,Spratt NJ,Parsons MW

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In primary intracerebral hemorrhage, the presence of contrast extravasation after computed tomographic angiography (CTA), termed the spot sign, predicts hematoma expansion and mortality. Because the biological underpinnings of the spot sign are not fully understood, we investigated whether the ra...

journal_title：Stroke

authors： Brouwers HB,Battey TW,Musial HH,Ciura VA,Falcone GJ,Ayres AM,Vashkevich A,Schwab K,Viswanathan A,Anderson CD,Greenberg SM,Pomerantz SR,Ortiz CJ,Goldstein JN,Gonzalez RG,Rosand J,Romero JM

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autopsy series of patients with AIDS have found a 4% to 29% prevalence of cerebral infarction. Little is known of the prevalence of cerebral infarction when not associated with non-HIV central nervous system (CNS) infection, lymphoma, or cardioembolic sources. Clinical correlation has seldom been...

journal_title：Stroke

authors： Connor MD,Lammie GA,Bell JE,Warlow CP,Simmonds P,Brettle RD

更新日期：2000-09-01 00:00:00

abstract：:We measured cerebral blood flow and somatosensory evoked potentials during transient focal cerebral ischemia in cats to compare the effects of four commonly used anesthetic regimens: ketamine/fentanyl/N2O (fentanyl), pentobarbital, ketamine/alpha-chloralose (alpha-chloralose), and ketamine/halothane/N2O (halothane). S...

journal_title：Stroke

authors： Helfaer MA,Kirsch JR,Traystman RJ

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke has been shown to alter autonomic function. The purpose of this study was to show the differential effects of stroke localization on autonomic function parameters assessed by heart rate variability (HRV). METHODS:To determine the differential effect of ischemic stroke localization on auto...

journal_title：Stroke

authors： Tokgözoglu SL,Batur MK,Topçuoglu MA,Saribas O,Kes S,Oto A

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Nonaneurysmal perimesencephalic hemorrhage, a distinct form of subarachnoid hemorrhage, is a recently described variant of intracranial hemorrhage. We describe two patients who presented with unusual features of this type of subarachnoid hemorrhage and also two patients who had a perimesencephalic pattern of...

journal_title：Stroke

authors： Schievink WI,Wijdicks EF,Piepgras DG,Nichols DA,Ebersold MJ

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some clinical models, like California ABCD and unified ABCD2 scores, are now available to predict the early risk of stroke after a TIA. Despite the transitivity of symptoms, DWI identified an area of acute brain ischemia in almost half of patients. It would be interesting to know how the presence...

journal_title：Stroke

authors： Purroy F,Begué R,Quílez A,Piñol-Ripoll G,Sanahuja J,Brieva L,Setó E,Gil MI

更新日期：2009-06-01 00:00:00

abstract：:Background and Purpose- Hemispheric stroke studies associating lateropulsion (pusher syndrome) with the location of brain lesions have had mixed results from small, unmatched samples. This study was designed to determine whether lateropulsion localizes to specific brain regions across patients with stroke using a case...

journal_title：Stroke

authors： Babyar SR,Smeragliuolo A,Albazron FM,Putrino D,Reding M,Boes AD

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study is to assess whether the PHASES score allows to (1) match decisions taken by multidisciplinary team whether to observe or intervene, (2) classify patients being diagnosed with a ruptured versus unruptured intracranial aneurysm (UIA), and (3) discriminate patients at low risk...

journal_title：Stroke

authors： Bijlenga P,Gondar R,Schilling S,Morel S,Hirsch S,Cuony J,Corniola MV,Perren F,Rüfenacht D,Schaller K

更新日期：2017-08-01 00:00:00

abstract：:Background and Purpose- Aneurysmal subarachnoid hemorrhage (aSAH) has a high healthcare cost burden. Methods- We performed a cross-sectional analysis of the costs of clipping and coiling of aSAH using the National Inpatient Sample and Vizient databases. We conducted multiple regression analyses to estimate national co...

journal_title：Stroke

authors： Yoon S,Yoon JC,Winkler E,Liu C,Lawton MT

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of single-nucleotide polymorphisms (SNPs) associated with increased risk of new intracranial hemorrhage (ICH) after brain arteriovenous malformation (BAVM) diagnosis would facilitate risk stratification and identify potential targets for therapeutic intervention. METHODS:Patients ...

journal_title：Stroke

authors： Achrol AS,Pawlikowska L,McCulloch CE,Poon KY,Ha C,Zaroff JG,Johnston SC,Lee C,Lawton MT,Sidney S,Marchuk DA,Kwok PY,Young WL,UCSF BAVM Study Project.

更新日期：2006-01-01 00:00:00

abstract：:The literature on carotid surgery for lesions appropriate to prior episodes of ischemia has been reviewed. Only one randomized study and six non-controlled reports give useful data (this despite more than thirty years of surgical activity in this field). When analyzed by the IMPS (intact months of patient survival) cr...

journal_title：Stroke

authors： Jonas S

更新日期：1986-11-01 00:00:00

abstract：:In experiments carried out on adult rabbit "chest-head" preparations the volume changes of the exposed brain (BrV) were determined in repeated tests during a controlled increase of the systemic venous pressure (SVP) of about 13 mm Hg. The changes of both SVP and BrV were usually parallel at the onset of the experiment...

journal_title：Stroke

authors： Mchedlishvili G,Nikolaishvili L,Itkis M

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although modern multisequence stroke MRI protocols are an emerging imaging routine for the diagnostic assessment of acute ischemic stroke, their sensitivity for intracerebral hemorrhage (ICH), the most important differential diagnosis, is still a matter of debate. We hypothesized that stroke MRI ...

journal_title：Stroke

authors： Fiebach JB,Schellinger PD,Gass A,Kucinski T,Siebler M,Villringer A,Olkers P,Hirsch JG,Heiland S,Wilde P,Jansen O,Röther J,Hacke W,Sartor K,Kompetenznetzwerk Schlaganfall B5.

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:An increase in intima-media thickness (IMT) in the common carotid artery (CCA) is commonly used as a marker of atherosclerosis. The purpose of this study was to investigate the relationship between IMT in the CCA and atherosclerosis in the carotid bifurcation. METHODS:182 consecutive patients (m...

journal_title：Stroke

authors： Rosfors S,Hallerstam S,Jensen-Urstad K,Zetterling M,Carlström C

更新日期：1998-07-01 00:00:00

abstract：:The effects of halothane on intracellular membrane potential (Em) and force development in cat MCA were studied. Halothane (0.07-0.14 mM/1) relaxed isolated MCA which had developed myogenic tone. Measurement of Em showed that halothane depolarized this preparation in a dose-dependent fashion in the face of vessel rela...

journal_title：Stroke

authors： Harder DR,Gradall K,Madden JA,Kampine JP

更新日期：1985-07-01 00:00:00

abstract：:A 51-yearold man with moderate intermittent hypertension had a rapidly progressive, profound dementia in the absence of significant localizing neurological signs. Postmortem examination disclosed the vascular alterations and diffuse white matter degeneration which characterize subcortical arteriosclerotic encephalopat...

journal_title：Stroke

authors： Burger PC,Burch JG,Kunze U

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is evidence of unequal access to health care interventions even where universal health systems operate. We investigated associations between patients' sociodemographic characteristics and the provision of acute and longer-term stroke care in a multiethnic urban population. METHODS:We used ...

journal_title：Stroke

authors： McKevitt C,Coshall C,Tilling K,Wolfe C

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The inflammatory response within cerebral infarcts may have an influence on tissue damage. Since old animals with an impaired immune response have decreased inflammation after experimental cerebral infarction, we postulated that female animals with an increased immune response will have an increa...

journal_title：Stroke

authors： Li K,Futrell N,Tovar S,Wang LC,Wang DZ,Schultz LR

更新日期：1996-03-01 00:00:00

abstract：:Choline concentration is rate limiting in the synthesis of acetylcholine. There is a negative arteriovenous difference for choline concentration across the brain, indicating the steady output of choline from this organ. Cerebral ischemia may increase extracellular choline concentration by interfering with its removal ...

journal_title：Stroke

authors： Scremin OU,Jenden DJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mild hypothermia has been shown to ameliorate neuronal damage due to cerebral ischemia. In our study, the influence of mild-to-moderate hypothermia was examined in a rabbit model of focal cerebral ischemia. METHODS:After 4 hours of permanent ischemia induced by occlusion of the anterior and midd...

journal_title：Stroke

authors： Lo EH,Steinberg GK

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Administration of histamine receptor antagonists has been reported to produce contradictory results, either reducing or increasing neural damage induced by ischemia. In this study, we investigated the neuroprotective effects of histamine H2-receptor antagonists in an "in vitro" model of ischemia....

journal_title：Stroke

authors： Malagelada C,Xifró X,Badiola N,Sabrià J,Rodríguez-Alvarez J

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preclinical data suggest that cell-based therapies have the potential to improve stroke outcomes. METHODS:Eighteen patients with stable, chronic stroke were enrolled in a 2-year, open-label, single-arm study to evaluate the safety and clinical outcomes of surgical transplantation of modified bon...

journal_title：Stroke

authors： Steinberg GK,Kondziolka D,Wechsler LR,Lunsford LD,Coburn ML,Billigen JB,Kim AS,Johnson JN,Bates D,King B,Case C,McGrogan M,Yankee EW,Schwartz NE

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Outcome after acute stroke is determined to a large extent by poststroke complications. Nutritional status and metabolic balance may substantially contribute to outcome after stroke. Key mechanisms of stroke pathophysiology can induce systemic catabolic imbalance with impaired metabolic efficienc...

journal_title：Stroke

authors： Scherbakov N,Dirnagl U,Doehner W

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Admission infarct core lesion size is an important determinant of management and outcome in acute (<9 hours) stroke. Our purposes were to: (1) determine the optimal CT perfusion parameter to define infarct core using various postprocessing platforms; and (2) establish the degree of variability in...

journal_title：Stroke

authors： Kamalian S,Kamalian S,Maas MB,Goldmacher GV,Payabvash S,Akbar A,Schaefer PW,Furie KL,Gonzalez RG,Lev MH

更新日期：2011-07-01 00:00:00

abstract：:Neurologic deficits that occur simultaneously with or subsequent to internal carotid artery occlusion may be influenced by the adequacy of the intracerebral collateral circulation. Transcranial Doppler ultrasonography was used to evaluate mean middle cerebral artery blood velocity and blood flow in major collateral ar...

journal_title：Stroke

authors： Schneider PA,Rossman ME,Bernstein EF,Torem S,Ringelstein EB,Otis SM

更新日期：1988-05-01 00:00:00