Abstract:
BACKGROUND AND PURPOSE:The purpose of this study was to assess brain perfusion with an ultrasound contrast-specific imaging mode and to prove if the results are comparable between 2 centers using a standardized study protocol. METHODS:A total of 32 individuals without known cerebrovascular disease were included in the study. Perfusion studies were performed ipsilaterally in an axial diencephalic plane after intravenous administration of 0.75 mL of Optison. Offline time intensity curves (TIC) were generated in different anatomic regions. Both centers used identical study protocols, ultrasound machines, and contrast agent. RESULTS:In both centers, the comparison of the parameter time to peak intensity (TPI) revealed significantly shorter TPIs in the main vessel structures compared with any parenchymal region of interest (ROI), whereas no significant differences were seen between the parenchymal ROIs. The parameter peak intensity (PI) varied widely interindividually in both centers, whereas the inter-ROI comparison revealed statistical significance (P < 0.05) in most of the cases according to the following pattern: (1) lentiforme nucleus > thalamus and white matter region, (2) thalamus > white matter region, and (3) main vessel > any parenchymal structure. Similar results were achieved in both centers independently. CONCLUSIONS:The study demonstrates that brain perfusion assessment with an ultrasound contrast-specific imaging mode is comparable between different centers using the same study protocol.
journal_name
Strokejournal_title
Strokeauthors
Hölscher T,Wilkening W,Draganski B,Meves SH,Eyding J,Voit H,Bogdahn U,Przuntek H,Postert Tdoi
10.1161/01.STR.0000179038.63109.b0subject
Has Abstractpub_date
2005-10-01 00:00:00pages
2283-5issue
10eissn
0039-2499issn
1524-4628pii
01.STR.0000179038.63109.b0journal_volume
36pub_type
杂志文章,多中心研究相关文献
STROKE文献大全abstract::Background and Purpose- Identifying the etiology of acute ischemic stroke is essential for effective secondary prevention. However, in at least one third of ischemic strokes, existing investigative protocols fail to determine the underlying cause. Establishing etiology is complicated by variation in clinical practice,...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.027123
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Previous studies on the hyperdense middle cerebral artery (MCA) sign were conducted using > or =5-mm thickness noncontrast-computed tomography (NCT). The purpose of this study was to compare thin-section NCT with 5-mm NCT in the detection of thrombus in acute ischemic stroke. METHODS:Enrolled we...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000185720.03803.41
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Randomized clinical trials testing aspirin in relatively low-risk, middle-aged people have consistently shown small increases in stroke associated with aspirin use. We analyzed the relationship between the regular use of aspirin and incident ischemic and hemorrhagic stroke among people aged 65 ye...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1161/01.str.29.5.887
更新日期:1998-05-01 00:00:00
abstract::As part of the Ni-Hon-San Study, stroke incidence was compared in the Japan and Hawaii cohorts. Stroke cases were classified in two types, intracranial hemorrhage (ICH) and thrombo-embolic stroke (T-E). For each type the incidence in Japan was about three times as great as in Hawaii. The ratio ICH/T-E was 1/2.2 and 1/...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.15.1.15
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Preischemic spontaneous locomotor activity was distinguished in this laboratory as a factor influencing outcome after 15 and 20 minutes of forebrain ischemia in gerbils. Histological investigations were carried out to analyze potential relations between postischemic survival and a reduction of ce...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.9.1862
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, in this study, the authors aimed to clarify whether OEF is e...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000198878.66000.4e
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There are few studies analyzing stroke in women, taking into account the vascular risk factors, cause of stroke, clinical picture, and outcome. The purpose of this study was to analyze possible sex differences in patients suffering first-ever acute stroke. METHODS:From December 1995 to January 2...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000078562.82918.F6
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Sonothrombolysis is a new treatment approach in acute ischemic stroke. The results of a monocenter, randomized clinical study are presented. METHODS:Subjects with acute middle cerebral artery main stem occlusion were randomized into a target group receiving 1-hour transcranial continuous insonat...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.107.503870
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The Combined Lysis of Thrombus in Brain Ischemia With Transcranial Ultrasound and Systemic T-PA-Hands-Free (CLOTBUST-HF) study is a first-in-human, National Institutes of Health-sponsored, multicenter, open-label, pilot safety trial of tissue-type plasminogen activator (tPA) plus a novel operator...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.002713
更新日期:2013-12-01 00:00:00
abstract::A woman who presented with a subarachnoid hemorrhage secondary to a ruptured anterior spinal artery aneurysm of the spinal cord is reported. While this is the first report of a ruptured aneurysm of the anterior spinal artery with angiographic confirmation, it emphasizes that occasionally subarachnoid hemorrhage may be...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.12.2.230
更新日期:1981-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Numerous studies have demonstrated higher stroke mortality rates in adults residing in the Southeastern United States (the "Stroke Belt"). If the Stroke Belt is solely caused by regional differences in atherosclerotic stroke risk factors, it should not apply to children. METHODS:For the years 19...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000130514.21773.95
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke is a debilitating disease with long-term social and economic consequences. As new therapies for acute ischemic stroke are forthcoming, there is an increasing need to understand their long-term economic implications. To address this need, a stroke economic model was created. METHODS:The mo...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.12.2574
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Exogenously administered fructose-1,6-bisphosphate reduces neuronal injury from hypoxic or ischemic brain insults. To test the hypothesis that fructose-1,6-bisphosphate prevents changes in intracellular calcium ([Ca2+]i) and high-energy phosphate levels, we measured [Ca2+]i, intracellular pH (pHi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.11.1617
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Post hoc analyses of randomized controlled clinical trials evaluating mechanical thrombectomy have suggested that admission-to-groin-puncture (ATG) delays are associated with reduced reperfusion rates. Purpose of this analysis was to validate this association in a real-world cohort and to find as...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.030208
更新日期:2020-10-01 00:00:00
abstract::We used 44 splenectomized dogs to study the effects of isovolemic hemodilution with a crystalloid solution. The dogs were randomly divided into a hemodilution and a control group. In each group, 17 dogs were subjected to 6 hours of internal carotid and middle cerebral artery occlusion, and five dogs received sham oper...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.4.534
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The pathogenesis of periventricular hyperintensity (PVH) is still uncertain. We investigated the relationship between PVH and risk factors for cerebrovascular diseases, especially extracranial carotid artery stenosis (ECAS). METHODS:We studied PVH and ECAS in 323 subjects between 1991 and 1994. ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.11.2174
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Some stroke patients complain of an unpleasant sensation of coldness in the hemiplegic arm. This study aimed to determine the prevalence of this symptom and any associated features. METHODS:A questionnaire about symptoms in the arms was sent to patients at least 12 months after stroke. Reflex sy...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.10.1867
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The association among socioeconomic status, quality of care, and clinical outcome after stroke remains poorly understood. In a Danish nationwide follow-up study, we examined whether socioeconomic-related differences in acute stroke care occur and, if so, whether they explain socioeconomic differe...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.611871
更新日期:2011-10-01 00:00:00
abstract::As part of a prospective study of the neurologic and neuropsychological complications of coronary artery bypass graft surgery, 312 patients were compared with a control group of 50 patients undergoing major surgery for peripheral vascular disease. The purpose of comparing the 2 groups was to determine to what extent n...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.4.700
更新日期:1987-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke guidelines recommend time-limited trials of nasogastric feeding prior to percutaneous endoscopic gastrostomy (PEG) tube placement. We sought to describe timing of PEG placement and identify factors associated with early PEG for acute ischemic stroke. METHODS:We designed a retrospective ob...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.015119
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Recanalization status after intravenous thrombolysis (IVT) in patients with ischemic stroke is a reference point to proceed with a rescue reperfusion intervention, although early neurological improvement (NI) may preclude endovascular procedures. We aimed to evaluate the importance of restoration...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.000048
更新日期:2013-09-01 00:00:00
abstract::Background and Purpose- Multifaceted quality improvement interventions of stroke care have been shown to improve hospital personnel adherence to evidence-based performance measures and subsequent stroke outcomes. This study aimed to evaluate the cost-effectiveness of a multifaceted quality improvement intervention for...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.027980
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this study was to identify quantitative trait loci (QTL) for carotid intima-media thickness (CIMT) a risk factor for stroke and cardiovascular disease. METHODS:Probands were selected from Caribbean Hispanic subjects of the population-based Northern Manhattan Study. CIMT was measured b...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.554121
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Dysphagia is common after stroke and is a marker of poor prognosis. Early identification is important. This article reviews the merits and limitations of various assessment methods available to clinicians. METHODS:An electronic database search was performed of MEDLINE, EMBASE, and the Cochrane d...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.STR.0000066309.06490.B8
更新日期:2003-05-01 00:00:00
abstract::We studied the pattern and outcome of strokes in 200 Saudi patients. Cerebral infarction constituted 87% of strokes, subarachnoid hemorrhage 4.5%, cerebral hemorrhage 6.5%, and venous infarction 2%. The vessel most commonly involved was part or all of the middle cerebral artery, constituting 52% (90) of the 174 arteri...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.9.1173
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Develop achievable benchmarks for 9 stroke performance measures (PM) and to identify organizational factors associated with adherence. METHODS:Adherence rates and achievable benchmarks were determined for 9 PM within a study of patients (n=2294) admitted with acute ischemic stroke at 17 hospital...
journal_title:Stroke
pub_type: 信件,多中心研究
doi:10.1161/STROKEAHA.107.496570
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:This study was conducted to analyze the association between reported risk factors for Alzheimer's disease, apolipoprotein E epsilon4 allele, and cardiovascular disease and neuropathological changes essential for the diagnosis of Alzheimer's disease. METHODS:Our data are based on clinical and pos...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.3.613
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Thrombolytic treatment of stroke carries the risk of hemorrhagic transformation. Therefore, the potential of MRI for prediction of recombinant tissue plasminogen activator (rtPA)-induced bleeding is explored to identify patients in whom rtPA treatment may provoke such complications. METHODS:Spon...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.0000014619.59851.65
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We aimed to investigate the associations of dietary and total potassium, magnesium, and calcium intakes with stroke occurrence. METHODS:A prospective cohort study was conducted among 36 094 participants aged 21 to 70 years. Dietary intake was assessed with a food frequency questionnaire. RESULT...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.004032
更新日期:2014-04-01 00:00:00
abstract::Previous studies suggest that rheological changes associated with ischemia may produce postischemic hypoperfusion. We tested whether intracarotid or intravenous infusions of saline improve neurological outcome from incomplete cerebral ischemia in rats. Rats were anesthetized with 1.4% isoflurane in air, and ischemia w...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.6.797
更新日期:1991-06-01 00:00:00