Abstract:
BACKGROUND AND PURPOSE:Recent innovations such as CT installation in ambulances may lead to earlier start of stroke-specific treatments. However, such technically complex mobile facilities require effective methods of correctly identifying patients before deployment. We aimed to develop and validate a new dispatcher identification algorithm for stroke emergencies. METHODS:Dispatcher identification algorithm for stroke emergencies was informed by systematic qualitative analysis of the content of emergency calls to ambulance dispatchers for patients with stroke or transient ischemic attack (N=117) and other neurological (N=39) and nonneurological (N=51) diseases (Part A). After training of dispatchers, sensitivity and predictive values were determined prospectively in patients admitted to Charité hospitals by using the discharge diagnosis as reference standard (Part B). RESULTS:Part A: Dysphasic/dysarthric symptoms (33%), unilateral symptoms (22%) and explicitly stated suspicion of stroke (47%) were typically identified in patients with stroke but infrequently in nonstroke cases (all <10%). Convulsive symptoms (41%) were frequent in other neurological diseases but not strokes (3%). Pain (26%) and breathlessness (31%) were often expressed in nonneurological emergencies (6% and 7% in strokes). Part B: Between October 15 and December 16, 2010, 5774 patients were admitted by ambulance with 246 coded with final stroke diagnoses. Sensitivity of dispatcher identification algorithm for stroke emergencies for detecting stroke was 53.3% and positive predictive value was 47.8% for stroke and 59.1% for stroke and transient ischemic attack. Of all 275 patients with stroke dispatcher codes, 215 (78.5%) were confirmed with neurological diagnosis. CONCLUSIONS:Using dispatcher identification algorithm for stroke emergencies, more than half of all patients with stroke admitted by ambulance were correctly identified by dispatchers. Most false-positive stroke codes had other neurological diagnoses.
journal_name
Strokejournal_title
Strokeauthors
Krebes S,Ebinger M,Baumann AM,Kellner PA,Rozanski M,Doepp F,Sobesky J,Gensecke T,Leidel BA,Malzahn U,Wellwood I,Heuschmann PU,Audebert HJdoi
10.1161/STROKEAHA.111.634980subject
Has Abstractpub_date
2012-03-01 00:00:00pages
776-81issue
3eissn
0039-2499issn
1524-4628pii
STROKEAHA.111.634980journal_volume
43pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Studies of peripheral arteries in hypercholesterolemic animals suggest that increased generation of superoxide contributes to endothelial dysfunction, especially in the presence of atherosclerotic lesions. We tested the hypothesis that vasomotor function is impaired in cerebral arterioles during ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.481879
更新日期:2007-07-01 00:00:00
abstract::A new technique is described for the autoradiographic determination of regional brain glucose metabolism employing 14C labeled glucose as substrate and measurement principles previously described for whole brain. Regional glucose values correlate closely with those reported for the 14C-deoxyglucose technique. The meth...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.10.6.690
更新日期:1979-11-01 00:00:00
abstract::Recent success with thrombolytic therapy for acute myocardial infarction has stimulated interest in its use for stroke. To determine the hemorrhagic potential of thrombolytic therapy in experimental cerebral infarction, we compared a group of tissue plasminogen activator-treated rabbits (n = 4) with 2 groups of strept...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.6.1148
更新日期:1987-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several observations indicate that, during energy deprivation, endogenous dopamine may become neurotoxic. Accordingly, the nucleus striatum is a preferential site of silent infarcts in humans, and experimental ischemia caused by homolateral carotid occlusion selectively damages this dopamine-enri...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.0000038093.42512.0f
更新日期:2002-12-01 00:00:00
abstract::Stroke is a complex disease, with both genetic and environmental factors having a role in its pathogenesis. A review of past studies shows some evidence of genetic influences in the development of stroke. This is supported by studies of cardiovascular disease, which indicate major genetic influences at several levels ...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Calcium (Ca(2+)) plays a role in the cellular and molecular pathways of ischemic neuronal death. We evaluated the impact of both early and delayed Ca(2+) levels on clinical outcomes from acute ischemic stroke. METHODS:The relations between blood calcium level obtained early (<4.5 hours), and del...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.513499
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The objective is to compare the effects of high-intensity interval training (HIIT) with long versus short intervals on endurance and motor performance. Their influence on neuroplasticity markers is assessed in the ipsilesional and contralesional cortex and hippocampus since their remodeling could...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.031873
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The antiplatelet agent sarpogrelate is a selective inhibitor of 5-hydroxytryptamine receptors. The purpose of this study was to compare the efficacy and safety of sarpogrelate with those of aspirin in Japanese ischemic stroke patients. METHODS:In total, 1510 patients with recent cerebral infarct...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.107.505131
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Uric acid (UA) is a neuroprotective antioxidant that improves the benefits of alteplase in experimental ischemia. However, it is unknown whether endogenous UA also influences the response to thrombolysis in patients with stroke. METHODS:A total of 317 consecutive patients treated with thrombolys...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/STROKEAHA.110.596528
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The consequences of stroke are a major health concern. This study was conducted to compare the health-related quality of life among long-term survivors of stroke with that of the general population. METHODS:Our data are taken from a population-based case-control study of all 6-year survivors of ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.31.2.440
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Few pediatric reports of thrombolysis exist. We sought to determine national rates of thrombolysis among pediatric ischemic stroke patients using a national database. METHODS:Patients between the ages of 1 and 17 years, entered in the Nationwide Inpatient Sample between 2000 and 2003, with Inter...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.106.473983
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The Pediatric National Institutes of Health Stroke Scale (PedNIHSS), an adaptation of the adult National Institutes of Health Stroke Scale, is a quantitative measure of stroke severity shown to be reliable when scored prospectively. The ability to calculate the PedNIHSS score retrospectively woul...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.111.633305
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Ventricular assist devices (VADs) have advanced the management of end-stage heart failure. However, these devices are associated with hemorrhagic and thrombotic complications, including stroke. We assessed the incidence, risk factors, and outcomes of ischemic and hemorrhagic stroke after VAD plac...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.014049
更新日期:2016-11-01 00:00:00
abstract::In a postasphyxia neonatal lamb model, the responses of the cerebral circulation to hypoxic hypoxia and changes in systemic arterial blood pressure were examined. Ventilated newborn lambs (n = 14) were subjected to a gradual asphyxial insult, resuscitated, and returned to control ventilator settings. During the time 2...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.2.239
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Persons with early stages of chronic kidney disease, defined by a decreased glomerular filtration rate (GFR), have an increased risk of cardiovascular disease. It is unclear whether decreased GFR is a risk factor for stroke. We assessed the association between GFR and stroke in a prospective popu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.489807
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Data are scarce on both stroke incidence rates and outcomes in Greece and in rural areas in particular. We performed a prospective population-based study evaluating the incidence of first-ever stroke in the Evros prefecture, a region of a total 147 947 residents located in North Eastern Greece. ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019524
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We hypothesize that reversal in diffusion-weighted imaging (DWI) volume at 24 hours predicts favorable clinical outcome only if accompanied by immediate reperfusion. Our aim was to quantify the immediate DWI and mean transit time changes at 2 and 24 hours after intravenous tissue-type plasminogen...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.006082
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Short-term elevations in fine particulate matter air pollution (PM2.5) are associated with increased risk of acute cerebrovascular events. Evidence from the peripheral circulation suggests that vascular dysfunction may be a central mechanism. However, the effects of PM2.5 on cerebrovascular funct...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.000395
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The limited walking ability that follows a stroke restricts the patient's independent mobility about the home and community, a significant social handicap. To improve the in-hospital prediction of functional outcome, the relationships between impairment, disability, and handicap were assessed wit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.6.982
更新日期:1995-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:It is important to know the costs of hospitalization for patients undergoing endovascular embolectomy so that comparisons can be made with payments to hospitals. METHODS:Using the National Inpatient Sample, we evaluated the costs of hospitalization for patients treated with endovascular embolect...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.618405
更新日期:2011-11-01 00:00:00
abstract::Using a scintillation camera system, hemispheric and regional cerebral blood flow was measured repeatedly during the course after a stroke. In 20 patients who improved clinically mean hemispheric and regional flow and relative weight of rapidly perfused compartment increased, while these values decreased in 15 patient...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.7.4.399
更新日期:1976-07-01 00:00:00
abstract::Using in vivo brain microdialysis, we studied amino acid release in the striatum and cortex of eight rats following permanent middle cerebral artery occlusion. We then processed all brains for histopathologic assessment of the volume of ischemic damage 4 hours after occlusion. Ischemic damage was varied by occlusion o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.12.1727
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Spontaneous echo contrast (SEC) is thought to represent a risk factor for cardioembolic stroke. In vitro studies suggest that SEC results from interaction between red cells and fibrinogen. To better understand the relation between SEC and stroke and to investigate the in vivo genesis of SEC, we e...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.8.1564
更新日期:1994-08-01 00:00:00
abstract::An overview of the possible factors that might contribute to the development of cerebral vasospasm is presented, with particular emphasis on the possibility that spasm arises from a malfunction of the regulatory or contractile processes in smooth muscle cells. This possibility is emphasized because the evidence for ce...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.16.4.573
更新日期:1985-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:5' adenosine monophosphate-dependent protein kinase (AMPK) acts as a metabolic sensor. AMPK is elevated under ischemic conditions, but the role of AMPK in ischemic brain remains controversial. In this study, we examined the effects of AMPK inhibition using both pharmacological and genetic approac...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.490904
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Recovery of patients within the first 6 months after stroke is well documented, but there has been little research on long-term recovery. The aim of this study was to analyze functional and motor recovery between admission to rehabilitation centres and 5 years after stroke. METHODS:This follow-u...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/STROKEAHA.115.009421
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cancer is a risk factor for ischemic stroke. Little is known about cancer among young adults with ischemic stroke. We studied the frequency of cancer and its association with long-term risk of death among young patients with first-ever ischemic stroke. METHODS:1002 patients aged 15 to 49 years, ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.115.008694
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, in this study, the authors aimed to clarify whether OEF is e...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000198878.66000.4e
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:One hundred twelve patients undergoing elective carotid endarterectomy for symptomatic and asymptomatic carotid artery stenosis were enrolled in a prospective study to evaluate the incidence of change in postoperative cerebral function. METHODS:Patients were evaluated preoperatively and postoper...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.29.6.1110
更新日期:1998-06-01 00:00:00
abstract::In normothermic anesthetized cats cerebral blood flow was interrupted completely for one hour by arterial clamping and induced hypotension. The effect of ischemia on the ionic gradients of the cerebral cortex was assayed by determining total cortical electrolytes and by recording the activities of extracellular potass...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.8.1.77
更新日期:1977-01-01 00:00:00