Regulation of cerebral blood flow after asphyxia in neonatal lambs.

abstract：BACKGROUND AND PURPOSE:The role of extracellular Ca2+ in the maintenance of chronic vasospasm after subarachnoid hemorrhage (SAH) is largely unknown. Indeed, studies thus far have been limited to demonstrations that L-type Ca(2+)-channel antagonists were unable to reverse the spasm. This study tested whether SAH-induce...

journal_title：Stroke

authors： Zuccarello M,Boccaletti R,Tosun M,Rapoport RM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to identify quantitative trait loci (QTL) for carotid intima-media thickness (CIMT) a risk factor for stroke and cardiovascular disease. METHODS:Probands were selected from Caribbean Hispanic subjects of the population-based Northern Manhattan Study. CIMT was measured b...

journal_title：Stroke

authors： Sacco RL,Blanton SH,Slifer S,Beecham A,Glover K,Gardener H,Wang L,Sabala E,Juo SH,Rundek T

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The joint effect of risk factors on the risk of aneurysmal SAH (aSAH) has been studied sparsely. METHODS:We examined the potential synergism between cigarette smoking, hypertension, and regular alcohol consumption and the risk of aSAH in a prospective, population-based cohort of participants fro...

journal_title：Stroke

authors： Lindekleiv H,Sandvei MS,Romundstad PR,Wilsgaard T,Njølstad I,Ingebrigtsen T,Vik A,Mathiesen EB

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cannabidiol has been reported to be a neuroprotectant, but the neuroprotective mechanism of cannabidiol remains unclear. We studied the neuroprotective mechanism of cannabidiol in 4-hour middle cerebral artery (MCA) occlusion mice. METHODS:Male MCA occluded mice were treated with cannabidiol, ab...

journal_title：Stroke

authors： Mishima K,Hayakawa K,Abe K,Ikeda T,Egashira N,Iwasaki K,Fujiwara M

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined whether hemodynamic and metabolic abnormalities in the cerebral white matter, basal ganglia, and thalamus are associated with asymptomatic white matter lesions (WML) depicted on MR images. METHODS:A positron emission tomographic study with H2(15)O, C15O, and 15O2 was performed in eig...

journal_title：Stroke

authors： Hatazawa J,Shimosegawa E,Satoh T,Toyoshima H,Okudera T

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in the elderly. We undertook an international survey to characterize the frequency of AF-associated stroke, methods of AF detection, and patient features. METHODS:Consecutive patie...

journal_title：Stroke

authors： Perera KS,Vanassche T,Bosch J,Swaminathan B,Mundl H,Giruparajah M,Barboza MA,O'Donnell MJ,Gomez-Schneider M,Hankey GJ,Yoon BW,Roxas A Jr,Lavallee P,Sargento-Freitas J,Shamalov N,Brouns R,Gagliardi RJ,Kasner SE,Pieroni

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A supraphysiological amount of vitamin E in the standard diet of laboratory animals may provide partial protection against cerebral ischemic damage in stroke models. The aim of the present study was to test the effect of dietary vitamin E on infarct volume in rats subjected to permanent focal cer...

journal_title：Stroke

authors： van der Worp HB,Bär PR,Kappelle LJ,de Wildt DJ

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The current report details our initial periprocedural experience with Wingspan (Boston Scientific/Target), the first self-expanding stent system designed for the treatment of intracranial atheromatous disease. METHODS:All patients undergoing angioplasty and stenting with the Gateway balloon-Wing...

journal_title：Stroke

authors： Fiorella D,Levy EI,Turk AS,Albuquerque FC,Niemann DB,Aagaard-Kienitz B,Hanel RA,Woo H,Rasmussen PA,Hopkins LN,Masaryk TJ,McDougall CG

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite rapid advancements in intracranial aneurysm management, there is no evidence as of yet that this has translated into improvement in overall prognosis. METHODS:We compared 2 periods of aneurysm management, 1998 to 2003 (n=1023 aneurysms) and 2007 to 2013 (n=1499 aneurysms), at a single, h...

journal_title：Stroke

authors： Chua MH,Griessenauer CJ,Stapleton CJ,He L,Thomas AJ,Ogilvy CS

更新日期：2016-03-01 00:00:00

abstract：:The effect of prostaglandin E1 on regional cerebral blood flow (rCBF) was studied with the intra-arterial 133Xe method in ten awake patients under local anesthesia. Measurements were taken from 16 areas of a hemisphere in seven patients, from 35 areas of a hemisphere in two patients and from 256 areas of a hemisphere ...

journal_title：Stroke

authors： Olesen J

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The majority of patients enrolled in SWIFT PRIME trial (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke) had computed tomographic perfusion (CTP) imaging before randomization; 34 patients were randomized after magnetic resonance imaging...

journal_title：Stroke

authors： Menjot de Champfleur N,Saver JL,Goyal M,Jahan R,Diener HC,Bonafe A,Levy EI,Pereira VM,Cognard C,Yavagal DR,Albers GW

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microembolic signals (MESs) are detectable within the transcranial Doppler frequency spectrum downstream from vascular atherothrombotic or cardiothrombotic lesions. A frequent occurrence of MESs has also been shown during bypass surgery or after mechanical valve implantation. We sought to compile...

journal_title：Stroke

authors： Dittrich R,Ringelstein EB

更新日期：2008-02-01 00:00:00

abstract：:Two hundred fifteen consecutive patients with cerebrovascular events were evaluated prospectively for the incidence and characteristics of headache. Of 163 patients able to communicate, headache occurred in 29% with bland infarcts, 57% with parenchymal hemorrhage, 36% with transient ischemic attacks and 17% with lacun...

journal_title：Stroke

authors： Portenoy RK,Abissi CJ,Lipton RB,Berger AR,Mebler MF,Baglivo J,Solomon S

更新日期：1984-11-01 00:00:00

abstract：:Background and Purpose- Imaging is frequently used to select acute stroke patients for intra-arterial therapy. Quantitative cerebral blood flow can be measured noninvasively with arterial spin labeling magnetic resonance imaging. Cerebral blood flow levels in the contralateral (unaffected) hemisphere may affect capaci...

journal_title：Stroke

authors： Thamm T,Guo J,Rosenberg J,Liang T,Marks MP,Christensen S,Do HM,Kemp SM,Adair E,Eyngorn I,Mlynash M,Jovin TG,Keogh BP,Chen HJ,Lansberg MG,Albers GW,Zaharchuk G

更新日期：2019-12-01 00:00:00

abstract：:The influence of chronic arterial hypertension upon the permeability to albumin of the cerebral capillaries, i.e. the blood-brain barrier, was studied in normotensive Wistar and spontaneously hypertensive Wistar rats with experimental subarachnoid hemorrhage. The blood-brain barrier permeability to albumin was assesse...

journal_title：Stroke

authors： Dóczi T,Joó F,Sonkodi S,Adám G

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Conventional diets may cause hyperglycemia in patients with neurological injuries. The purpose of this study was to examine the effect on the severity of cerebral infarction of replacing carbohydrates as the primary dietary source of nonprotein calories. METHODS:Sixty-nine Long-Evans rats were e...

journal_title：Stroke

authors： Robertson C,Goodman JC,Grossman RG,Claypool M,White A

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is unclear which harmonic imaging mode (power Doppler or gray-scale imaging) is superior and which measuring method is the most robust for the description of brain perfusion. METHODS:We performed an animal study on 6 beagles through the intact skull using a SONOS 5500 device and Optison injec...

journal_title：Stroke

authors： Seidel G,Algermissen C,Christoph A,Katzer T,Kaps M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Central nervous system serotonergic neurotransmission appears to play a role in mood disorders, eating habits, and sleep, and also modulates blood pressure and metabolism. This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis...

journal_title：Stroke

authors： Muldoon MF,Mackey RH,Sutton-Tyrrell K,Flory JD,Pollock BG,Manuck SB

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal. The unsuccessful outcome of several research programs highlights the need for reliable data on which to plan future clinical trials. The Virtual Internat...

journal_title：Stroke

authors： Ali M,Bath PM,Curram J,Davis SM,Diener HC,Donnan GA,Fisher M,Gregson BA,Grotta J,Hacke W,Hennerici MG,Hommel M,Kaste M,Marler JR,Sacco RL,Teal P,Wahlgren NG,Warach S,Weir CJ,Lees KR

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial arterial dolichoectasia (IADE) is a poorly understood arteriopathy compared with intracranial atherosclerotic stenosis (ICAS). We aimed to investigate the risk factors of IADE and ICAS and their relationship with neuroimaging markers of cerebral small vessel disease in a population-b...

journal_title：Stroke

authors： Zhai FF,Yan S,Li ML,Han F,Wang Q,Zhou LX,Ni J,Yao M,Zhang SY,Cui LY,Jin ZY,Zhu YC

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We compared two-dimensional time-of-flight magnetic resonance angiography (MRA) and duplex ultrasonography with arteriography for the detection of 70% to 99% stenoses at the carotid artery bifurcation (ie, surgical disease according to findings of the North American Carotid Endarterectomy Trial)....

journal_title：Stroke

authors： Mittl RL Jr,Broderick M,Carpenter JP,Goldberg HI,Listerud J,Mishkin MM,Berkowitz HD,Atlas SW

更新日期：1994-01-01 00:00:00

abstract：:Regional cerebral blood flow (CBF) was measured (intra-arterial injections of 133Xe) and electroencephalograms (EEG) were recorded periodically before, for two hours during, and for one and one-fourth hours after middle cerebral artery (MCA) occlusion in 20 squirrel monkeys (Saimiri sciureus). A CBF-Paco2 response cur...

journal_title：Stroke

authors： Donley RF,Sundt TM,Anderson RE,Sharbrough FW

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Abnormalities in endogenous fibrinolysis are associated with an increased risk for stroke in men and older adults. We tested the hypothesis that elevated plasma tissue plasminogen activator (tPA) antigen, a marker for impaired endogenous fibrinolysis, is an independent risk factor for stroke in y...

journal_title：Stroke

authors： Macko RF,Kittner SJ,Epstein A,Cox DK,Wozniak MA,Wityk RJ,Stern BJ,Sloan MA,Sherwin R,Price TR,McCarter RJ,Johnson CJ,Earley CJ,Buchholz DW,Stolley PD

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:By means of neurological and ophthalmologic examinations we considered whether there is a microcirculatory disorder not related to hypertension and diabetes in patients with lacunar infarcts and whether there are microcirculatory differences in patients with lacunar infarcts compared with those w...

journal_title：Stroke

authors： Schneider R,Rademacher M,Wolf S

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preceding infection as an important risk factor for ischemic stroke has been reported but neglected for hemorrhagic stroke, especially in young and middle-aged patients. This study investigates whether newly diagnosed leptospirosis is associated with an increased risk of stroke. METHODS:We ident...

journal_title：Stroke

authors： Li KY,Chou MC,Wei JC,Lin MC,Hung YM,Chang R

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND AND PURPOSE:The onset of spontaneous intracerebral hemorrhage (ICH) is often accompanied by transient blood pressure (BP) elevation. The prognostic value and the determinants of this BP reaction have not entirely been solved, and the present study was focused on these questions. METHODS:From 1985 to 1991 in...

journal_title：Stroke

authors： Fogelholm R,Avikainen S,Murros K

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The use of bare metal stents to treat symptomatic intracranial stenosis may be associated with significant restenosis rates. The advent of drug-eluting stents (DESs) in the coronary circulation has resulted in a reduction of restenosis rates. We report our technical success rate and short-term re...

journal_title：Stroke

authors： Gupta R,Al-Ali F,Thomas AJ,Horowitz MB,Barrow T,Vora NA,Uchino K,Hammer MD,Wechsler LR,Jovin TG

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelin receptor antagonists such as clazosentan decrease large-artery vasospasm after experimental and clinical subarachnoid hemorrhage. We used clazosentan to gain insight into the pathophysiology of subarachnoid hemorrhage by determining if decreasing vasospasm is associated with alleviatio...

journal_title：Stroke

authors： Sabri M,Ai J,Macdonald RL

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia is common after stroke and is a marker of poor prognosis. Early identification is important. This article reviews the merits and limitations of various assessment methods available to clinicians. METHODS:An electronic database search was performed of MEDLINE, EMBASE, and the Cochrane d...

journal_title：Stroke

authors： Ramsey DJ,Smithard DG,Kalra L

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Higher plasma total homocysteine (tHcy) levels have been associated with carotid atherosclerosis and cerebral infarction in whites. However, data regarding such associations are limited for Asians. This study examined associations between tHcy levels and severity of carotid atherosclerosis in Jap...

journal_title：Stroke

authors： Sasaki T,Watanabe M,Nagai Y,Hoshi T,Takasawa M,Nukata M,Taguchi A,Kitagawa K,Kinoshita N,Matsumoto M

更新日期：2002-06-01 00:00:00