Gender differences in presenting and prodromal stroke symptoms.

Abstract:

BACKGROUND AND PURPOSE:Prompt recognition of stroke symptoms is critical to timely treatment and women have increased delay to treatment. Women may be more likely to present with atypical symptoms, but this hypothesis has not been extensively evaluated. METHODS:We examined gender differences in the prevalence of presenting and prodromal stroke symptoms among 1107 consecutive patients hospitalized with neurologist-confirmed acute ischemic stroke. Patient demographics, clinical variables, and stroke symptoms were abstracted from medical records by trained abstractors using standardized forms. Estimates were age-standardized to the age distribution of men and women combined. Presenting symptoms occurred within 24 hours of incident stroke admission; prodromal symptoms occurred >or=24 hours of admission. RESULTS:Women were significantly older (P<0.001), more likely to have cardioembolic stroke (P<0.01), and less likely to receive aspirin (P=0.014) or statins (P<0.001). Thirty-five percent of the sample (n=389) reported prodromal symptoms. Women were more likely to have >or=1 somatic prodromal and presenting symptoms (P=0.03; P=0.008), but did not differ from men on specific somatic symptoms. Women did not differ from men in classic presenting stroke symptoms (P=0.89). CONCLUSIONS:Women did not differ significantly in the prevalence of traditional stroke symptoms but were more likely to have somatic presenting and prodromal symptoms. We found no differences in specific prodromal symptoms, making it difficult to craft a public health message about gender differences in early warning signs of stroke. These results suggest that the focus of stroke prevention education for women should continue to emphasize traditional stroke risk factors.

journal_name

Stroke

journal_title

Stroke

authors

Stuart-Shor EM,Wellenius GA,DelloIacono DM,Mittleman MA

doi

10.1161/STROKEAHA.108.543371

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

1121-6

issue

4

eissn

0039-2499

issn

1524-4628

pii

STROKEAHA.108.543371

journal_volume

40

pub_type

杂志文章

相关文献

STROKE文献大全
  • Genetics of cerebrovascular disease.

    abstract::Stroke is a complex disease, with both genetic and environmental factors having a role in its pathogenesis. A review of past studies shows some evidence of genetic influences in the development of stroke. This is supported by studies of cardiovascular disease, which indicate major genetic influences at several levels ...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:

    authors: Alberts MJ

    更新日期:1990-11-01 00:00:00

  • High Serum Level of Matrix Metalloproteinase-7 Is Associated With Increased Risk of Spontaneous Subarachnoid Hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Increased degradation of the extracellular matrix in the arterial wall by matrix metalloproteinases (MMPs) may be an important mechanism in the pathogenesis of intracranial aneurysms and subarachnoid hemorrhage (SAH). MMP-2 and MMP-9 have been suggested to be involved in matrix degradation preced...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.020660

    authors: Söderholm M,Nordin Fredrikson G,Nilsson J,Engström G

    更新日期:2018-07-01 00:00:00

  • Role of Computed Tomography Perfusion in Identification of Acute Lacunar Stroke Syndromes.

    abstract:BACKGROUND AND PURPOSE:Lacunar syndromes correlate with a lacunar stroke on imaging in 50% to 60% of cases. Computed tomography perfusion (CTP) is becoming the preferred imaging modality for acute stroke triage. We aimed to estimate the sensitivity, specificity, and predictive values for noncontrast computed tomography...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030455

    authors: Garcia-Esperon C,Visser M,Churilov L,Miteff F,Bivard A,Lillicrap T,Levi CR,Spratt NJ,Parsons MW

    更新日期:2021-01-01 00:00:00

  • Occurrence and Predictors of Falls in People With Stroke: Six-Year Prospective Study.

    abstract:BACKGROUND AND PURPOSE:The purpose was to investigate the occurrence of self-reported falls in people with stroke at 3, 6, and 12 months and 6 years post stroke and predictors for falls during 6 years. METHODS:A prospective study involving 121 people with stroke. Data were obtained through structured interviews and as...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.010496

    authors: Minet LR,Peterson E,von Koch L,Ytterberg C

    更新日期:2015-09-01 00:00:00

  • Clinical outcomes of carotid endarterectomy in patients with carotid artery tandem lesions.

    abstract:BACKGROUND AND PURPOSE:When carotid artery tandem lesions are present, the benefits of carotid endarterectomy (CEA) to reduce recurrent stroke remain uncertain. The present retrospective cohort study aimed to determine the clinical outcomes of CEA for carotid artery tandem stenosis that was diagnosed by contrast-enhanc...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.114.007181

    authors: Han Y,Park H,Kwon SU,Kang DW,Lee DH,Kwon H,Kwon TW,Cho YP,Kim GE

    更新日期:2014-11-01 00:00:00

  • High-resolution emboli detection and differentiation by characteristic postembolic spectral patterns.

    abstract:BACKGROUND AND PURPOSE:High-intensity transient signals (HITS) detected by transcranial Doppler ultrasonography correspond to microemboli in intracranial arteries. The purpose of this study was to develop new diagnostic criteria for the differentiation of these microembolic signals from artifact, based on a high-resolu...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.3.668

    authors: Ries F,Tiemann K,Pohl C,Bauer C,Mundo M,Becher H

    更新日期:1998-03-01 00:00:00

  • Cost of illness in subarachnoid hemorrhage: a German longitudinal study.

    abstract:BACKGROUND AND PURPOSE:Aneurysmal subarachnoid hemorrhage (SAH) is a cerebrovascular disease with a high mortality rate and severe disability. Longitudinal studies investigating health-economic costs in SAH are scare and only one of them analyzed cost-driving factors. The objective was to evaluate first-year costs in G...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.586826

    authors: Dodel R,Winter Y,Ringel F,Spottke A,Gharevi N,Müller I,Klockgether T,Schramm J,Urbach H,Meyer B

    更新日期:2010-12-01 00:00:00

  • Cilostazol for Secondary Prevention of Stroke and Cognitive Decline: Systematic Review and Meta-Analysis.

    abstract:BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...

    journal_title:Stroke

    pub_type: 杂志文章,meta分析

    doi:10.1161/STROKEAHA.120.029454

    authors: McHutchison C,Blair GW,Appleton JP,Chappell FM,Doubal F,Bath PM,Wardlaw JM

    更新日期:2020-08-01 00:00:00

  • Cerebral hypoperfusion during acute Kawasaki disease.

    abstract:BACKGROUND AND PURPOSE:Kawasaki disease is a febrile disease of children notable for systemic vasculitis. There have been many previous reports of various complications, including disorders of the central nervous system. We evaluated cerebral perfusion during the acute stage in patients with Kawasaki disease. METHODS:...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.7.1320

    authors: Ichiyama T,Nishikawa M,Hayashi T,Koga M,Tashiro N,Furukawa S

    更新日期:1998-07-01 00:00:00

  • Tumor-Like Presentation of Primary Angiitis of the Central Nervous System.

    abstract:BACKGROUND AND PURPOSE:We aimed to describe the clinical and imaging features of patients with tumor-like presentation of primary angiitis of the central nervous system. METHODS:We retrospectively analyzed 10 patients enrolled in the French primary angiitis of the central nervous system cohort, who initially presented...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.013917

    authors: de Boysson H,Boulouis G,Dequatre N,Godard S,Néel A,Arquizan C,Detante O,Bloch-Queyrat C,Zuber M,Touzé E,Bienvenu B,Aouba A,Guillevin L,Naggara O,Pagnoux C,French Vasculitis Study Group.

    更新日期:2016-09-01 00:00:00

  • Retrospective Methods Analysis of Semiautomated Intracerebral Hemorrhage Volume Quantification From a Selection of the STICH II Cohort (Early Surgery Versus Initial Conservative Treatment in Patients With Spontaneous Supratentorial Lobar Intracerebral Hae

    abstract:BACKGROUND AND PURPOSE:The ABC/2 method for calculating intracerebral hemorrhage (ICH) volume has been well validated. However, the formula, derived from the volume of an ellipse, assumes the shape of ICH is elliptical. We sought to compare the agreement of the ABC/2 formula with other methods through retrospective ana...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.117.016677

    authors: Haley MD,Gregson BA,Mould WA,Hanley DF,Mendelow AD

    更新日期:2018-02-01 00:00:00

  • Effect of lidocaine on somatosensory evoked response and cerebral blood flow after canine cerebral air embolism.

    abstract:BACKGROUND AND PURPOSE:Victims of air embolism often recover rapidly on hyperbaric treatment then deteriorate again, even if hyperbaric treatment is continued. In previous animal experiments, lidocaine has been shown to improve recovery of somatosensory evoked response amplitude after air embolism. However, animals in ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.23.10.1515

    authors: Dutka AJ,Mink R,McDermott J,Clark JB,Hallenbeck JM

    更新日期:1992-10-01 00:00:00

  • Tuberculosis and the risk of ischemic stroke: a 3-year follow-up study.

    abstract:BACKGROUND AND PURPOSE:The aim of this study is to estimate the risk of ischemic stroke during a 3-year follow-up period after a tuberculosis diagnosis using a nationwide, population-based study and a retrospective cohort design. METHOD:The study cohort comprised 2283 patients who had received treatment for tuberculos...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.109.567735

    authors: Sheu JJ,Chiou HY,Kang JH,Chen YH,Lin HC

    更新日期:2010-02-01 00:00:00

  • Aggressive mechanical clot disruption: a safe adjunct to thrombolytic therapy in acute stroke?

    abstract:BACKGROUND AND PURPOSE:This study evaluated the safety and efficacy of aggressive mechanical clot disruption (AMCD) in acute stroke patients with persisting middle cerebral artery (MCA) or internal carotid artery (ICA) occlusion after thrombolytic therapy. METHODS:Retrospective case series were used from a prospective...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000152331.93770.18

    authors: Noser EA,Shaltoni HM,Hall CE,Alexandrov AV,Garami Z,Cacayorin ED,Song JK,Grotta JC,Campbell MS 3rd

    更新日期:2005-02-01 00:00:00

  • Early Dysphagia Screening by Trained Nurses Reduces Pneumonia Rate in Stroke Patients: A Clinical Intervention Study.

    abstract:BACKGROUND AND PURPOSE:Dysphagia is a common stroke symptom and leads to serious complications such as aspiration and pneumonia. Early dysphagia screening can reduce these complications. In many hospitals, dysphagia screening is performed by speech-language therapists who are often not available on weekends/holidays, w...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.117.018157

    authors: Palli C,Fandler S,Doppelhofer K,Niederkorn K,Enzinger C,Vetta C,Trampusch E,Schmidt R,Fazekas F,Gattringer T

    更新日期:2017-09-01 00:00:00

  • Role of potassium channels in regulation of brain arteriolar tone: comparison of cerebrum versus brain stem.

    abstract:BACKGROUND AND PURPOSE:Potassium channels are important regulators of resting tone in large cerebral arteries, but their activity and distribution may vary according to vessel location and species studied. In the cerebral microcirculation in vivo, however, these channels appear to be silent at rest. Our goal was to det...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.32.1.218

    authors: Horiuchi T,Dietrich HH,Tsugane S,Dacey RG Jr

    更新日期:2001-01-01 00:00:00

  • Dysphagia after stroke: incidence, diagnosis, and pulmonary complications.

    abstract:OBJECTIVE:To determine the incidence of dysphagia and associated pulmonary compromise in stroke patients through a systematic review of the published literature. METHODS:Databases were searched (1966 through May 2005) using terms "cerebrovascular disorders," "deglutition disorders," and limited to "humans" for origina...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.STR.0000190056.76543.eb

    authors: Martino R,Foley N,Bhogal S,Diamant N,Speechley M,Teasell R

    更新日期:2005-12-01 00:00:00

  • Rate of Contrast Extravasation on Computed Tomographic Angiography Predicts Hematoma Expansion and Mortality in Primary Intracerebral Hemorrhage.

    abstract:BACKGROUND AND PURPOSE:In primary intracerebral hemorrhage, the presence of contrast extravasation after computed tomographic angiography (CTA), termed the spot sign, predicts hematoma expansion and mortality. Because the biological underpinnings of the spot sign are not fully understood, we investigated whether the ra...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.009659

    authors: Brouwers HB,Battey TW,Musial HH,Ciura VA,Falcone GJ,Ayres AM,Vashkevich A,Schwab K,Viswanathan A,Anderson CD,Greenberg SM,Pomerantz SR,Ortiz CJ,Goldstein JN,Gonzalez RG,Rosand J,Romero JM

    更新日期:2015-09-01 00:00:00

  • Feasibility and safety of inducing modest hypothermia in awake patients with acute stroke through surface cooling: A case-control study: the Copenhagen Stroke Study.

    abstract:BACKGROUND AND PURPOSE:Hypothermia reduces neuronal damage in animal stroke models. Whether hypothermia is neuroprotective in patients with acute stroke remains to be clarified. In this case-control study, we evaluated the feasibility and safety of inducing modest hypothermia by a surface cooling method in awake patien...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/01.str.31.9.2251

    authors: Kammersgaard LP,Rasmussen BH,Jørgensen HS,Reith J,Weber U,Olsen TS

    更新日期:2000-09-01 00:00:00

  • Role of the contralateral inferior frontal gyrus in recovery of language function in poststroke aphasia: a combined repetitive transcranial magnetic stimulation and positron emission tomography study.

    abstract:BACKGROUND AND PURPOSE:Functional neuroimaging studies have demonstrated right inferior frontal gyrus (IFG) activation in poststroke aphasia. It remains unclear whether this activation is essential for language performance. We tested this hypothesis in a positron emission tomography (PET) activation study during a sema...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000174487.81126.ef

    authors: Winhuisen L,Thiel A,Schumacher B,Kessler J,Rudolf J,Haupt WF,Heiss WD

    更新日期:2005-08-01 00:00:00

  • Enlarged perivascular spaces on MRI are a feature of cerebral small vessel disease.

    abstract:BACKGROUND AND PURPOSE:Enlarged perivascular spaces in the brain are common but generally overlooked and of uncertain pathophysiology. They may reflect underlying cerebral small vessel disease. We determined whether enlarged perivascular spaces were associated with lacunar stroke subtype and white matter hyperintensiti...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.109.564914

    authors: Doubal FN,MacLullich AM,Ferguson KJ,Dennis MS,Wardlaw JM

    更新日期:2010-03-01 00:00:00

  • Substantial observer variability in the differentiation between primary intracerebral hemorrhage and hemorrhagic transformation of infarction on CT brain imaging.

    abstract:BACKGROUND AND PURPOSE:CT remains the most commonly used imaging technique in acute stroke but is often delayed after minor stroke. Interobserver reliability in distinguishing hemorrhagic transformation of infarction from intracerebral hemorrhage may depend on delays to CT but has not been reported previously despite t...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.109.553933

    authors: Lovelock CE,Anslow P,Molyneux AJ,Byrne JV,Kuker W,Pretorius PM,Coull A,Rothwell PM

    更新日期:2009-12-01 00:00:00

  • Pediatric Stroke Belt: geographic variation in stroke mortality in US children.

    abstract:BACKGROUND AND PURPOSE:Numerous studies have demonstrated higher stroke mortality rates in adults residing in the Southeastern United States (the "Stroke Belt"). If the Stroke Belt is solely caused by regional differences in atherosclerotic stroke risk factors, it should not apply to children. METHODS:For the years 19...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000130514.21773.95

    authors: Fullerton HJ,Elkins JS,Johnston SC

    更新日期:2004-07-01 00:00:00

  • Continuation or Discontinuation of Anticoagulation in the Early Phase After Acute Ischemic Stroke.

    abstract:BACKGROUND AND PURPOSE:There is no consensus on whether anticoagulation should be continued or temporarily stopped in patients suffering acute ischemic stroke while using anticoagulation. We assessed treatment variations and outcomes in these patients. METHODS:Post hoc analysis of PASS (Preventive Antibiotics in Strok...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.021514

    authors: Groot AE,Vermeij JM,Westendorp WF,Nederkoorn PJ,van de Beek D,Coutinho JM

    更新日期:2018-07-01 00:00:00

  • Risk factors for spontaneous cerebral hematomas. Case-control study.

    abstract::In a case-control study of 73 cases of cerebral hematoma diagnosed by CT scan, significant risk factors were history of hypertension, chronic alcoholism, evidence of hepatic disease, EKG abnormalities and high hematocrit values. Initial blood pressure was significantly higher in cases, but blood pressure on the third ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.17.6.1126

    authors: Calandre L,Arnal C,Ortega JF,Bermejo F,Felgeroso B,del Ser T,Vallejo A

    更新日期:1986-11-01 00:00:00

  • Importance of cerebral artery recanalization in patients with stroke with and without neurological improvement after intravenous thrombolysis.

    abstract:BACKGROUND AND PURPOSE:Recanalization status after intravenous thrombolysis (IVT) in patients with ischemic stroke is a reference point to proceed with a rescue reperfusion intervention, although early neurological improvement (NI) may preclude endovascular procedures. We aimed to evaluate the importance of restoration...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.111.000048

    authors: Kharitonova TV,Melo TP,Andersen G,Egido JA,Castillo J,Wahlgren N,SITS investigators.

    更新日期:2013-09-01 00:00:00

  • Increased vulnerability of the blood-brain barrier to experimental subarachnoid hemorrhage in spontaneously hypertensive rats.

    abstract::The influence of chronic arterial hypertension upon the permeability to albumin of the cerebral capillaries, i.e. the blood-brain barrier, was studied in normotensive Wistar and spontaneously hypertensive Wistar rats with experimental subarachnoid hemorrhage. The blood-brain barrier permeability to albumin was assesse...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.17.3.498

    authors: Dóczi T,Joó F,Sonkodi S,Adám G

    更新日期:1986-05-01 00:00:00

  • Feeding artery pressure and venous drainage pattern are primary determinants of hemorrhage from cerebral arteriovenous malformations.

    abstract:PURPOSE:The purpose of this study was to define the influence of feeding mean arterial pressure (FMAP) in conjunction with other morphological or clinical risk factors in determining the probability of hemorrhagic presentation in patients with cerebral arteriovenous malformations (AVMs). METHODS:Clinical and angiograp...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.6.1167

    authors: Duong DH,Young WL,Vang MC,Sciacca RR,Mast H,Koennecke HC,Hartmann A,Joshi S,Mohr JP,Pile-Spellman J

    更新日期:1998-06-01 00:00:00

  • Recovery of upper limb function after cerebellar stroke: lesion symptom mapping and arm kinematics.

    abstract:BACKGROUND AND PURPOSE:Loss of movement coordination is the main postacute symptom after cerebellar infarction. Although the course of motor recovery has been described previously, detailed kinematic descriptions of acute stage ataxia are rare and no attempt has been made to link improvements in motor function to measu...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.583641

    authors: Konczak J,Pierscianek D,Hirsiger S,Bultmann U,Schoch B,Gizewski ER,Timmann D,Maschke M,Frings M

    更新日期:2010-10-01 00:00:00

  • Cardiac cycle-dependent alternating flow in vertebral arteries with subclavian artery stenoses.

    abstract::Continuous-wave Doppler sonography is a reliable method for detecting severe subclavian stenosis and occlusion as well as subclavian steal. Intermediate stages leading to subclavian steal can also be detected. These are characterized by a cardiac-phase-dependent alternating flow direction in the vertebral artery. Some...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.9.3.229

    authors: von Reutern GM,Pourcelot L

    更新日期:1978-05-01 00:00:00