High-resolution emboli detection and differentiation by characteristic postembolic spectral patterns.

abstract：BACKGROUND AND PURPOSE:Zinc protoporphyrin (ZnPP) has multiple actions. It is an interleukin-1 antagonist as well as a hemeoxygenase inhibitor. Interleukin-1 is produced in ischemic brain and probably contributes to ischemic injury, although the role of heme oxygenase during ischemia is unknown. Whether ZnPP treatment ...

journal_title：Stroke

authors： Kadoya C,Domino EF,Yang GY,Stern JD,Betz AL

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is the leading cause of disability in the Western world; however, few therapies are at hand to decrease this burden. SUMMARY OF REVIEW:Endothelial progenitor cells (EPCs) have been introduced in cardiovascular medicine as factotums. EPCs can repair damaged endothelium and attenuate the de...

journal_title：Stroke

authors： Rouhl RP,van Oostenbrugge RJ,Damoiseaux J,Tervaert JW,Lodder J

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lamotrigine (LTG) is an anticonvulsant drug whose mechanism of action may involve the inhibition of glutamate release by blocking voltage-dependent sodium channels. Glutamate neurotoxicity may contribute to cerebral ischemic damage after recovery from cardiac arrest. Thus, LTG may prevent the bra...

journal_title：Stroke

authors： Crumrine RC,Bergstrand K,Cooper AT,Faison WL,Cooper BR

更新日期：1997-11-01 00:00:00

abstract：:The plasma concentrations of protein C, an anticoagulant protein, and fibrinopeptide A were measured in 37 patients with acute hemispheric stroke and in age-matched controls with nonvascular neurologic diseases. In 11 stroke patients who died within 15 days after the onset (nonsurvivors) protein C antigen concentratio...

journal_title：Stroke

authors： D'Angelo A,Landi G,Vigano'D'Angelo S,Nobile Orazio E,Boccardi E,Candelise L,Mannucci PM

更新日期：1988-05-01 00:00:00

abstract：:There is a strong link between antiphospholipid antibodies and stroke. Retrospective studies indicate that these patients are generally young, often have had prior thrombotic events including stroke, frequently complain of headaches, and often experience amaurosis fugax. Cardiac valvular lesions, particularly involvin...

journal_title：Stroke

authors： Hess DC

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of the present study was to investigate the effects of normobaric oxygen (NBO) therapy on T2*-weighted images of intracranial hemorrhages (ICHs). METHODS:Two common models of ICH were performed in mice, and longitudinal T2*-weighted images of the hematomas were acquired under normoxia or...

journal_title：Stroke

authors： Gaberel T,Gakuba C,Hebert M,Montagne A,Agin V,Rubio M,Emery E,Vivien D,Gauberti M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies of the cerebroprotective effects of selective brain cooling have failed to show amelioration of ischemic injury in the cerebral cortex. This study was designed to test the hypothesis that mild-to-moderate selective brain cooling initiated after the onset of global brain ischemia in rats p...

journal_title：Stroke

authors： Kuluz JW,Gregory GA,Yu AC,Chang Y

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In ischemic stroke, diffusion-weighted (DW) and perfusion-weighted (PW) magnet resonance imaging (MRI) is used to define the mismatch as the therapeutic target. With positron emission tomography (PET), we characterized the metabolic patterns of tissue compartments identified by MRI and compared t...

journal_title：Stroke

authors： Sobesky J,Zaro Weber O,Lehnhardt FG,Hesselmann V,Neveling M,Jacobs A,Heiss WD

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A transient ischemic attack (TIA) in the brain is classically considered a syndrome lasting <24 hours. Having previously shown that an experimental challenge with the GABAA agonist midazolam in recovered stroke patients can reinduce the acute clinical state, we determined whether TIA patients wou...

journal_title：Stroke

authors： Lazar RM,Fitzsimmons BF,Marshall RS,Mohr JP,Berman MF

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Noncontrast computed tomographic (CT) hypodensities have been shown to be associated with hematoma expansion in intracerebral hemorrhage (ICH), but their impact on functional outcome is yet to be determined. We evaluated whether baseline noncontrast CT hypodensities are associated with poor clini...

journal_title：Stroke

authors： Boulouis G,Morotti A,Brouwers HB,Charidimou A,Jessel MJ,Auriel E,Pontes-Neto O,Ayres A,Vashkevich A,Schwab KM,Rosand J,Viswanathan A,Gurol ME,Greenberg SM,Goldstein JN

更新日期：2016-10-01 00:00:00

abstract：:Background and Purpose- Ischemic stroke is one of the leading causes of morbidity and mortality worldwide and a major cause of long-term disability. Recently, long noncoding RNAs have been revealed, which are tightly associated with several human diseases. However, the functions of long noncoding RNAs in ischemic stro...

journal_title：Stroke

authors： Deng Y,Chen D,Wang L,Gao F,Jin B,Lv H,Zhang G,Sun X,Liu L,Mo D,Ma N,Song L,Huo X,Yan T,Miao Z

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transorbital sonography may help establish diagnosis of central retinal artery occlusion (CRAO). Next to Doppler sonographic proof of CRAO, an intra-arterial spot sign can be detected in some cases. We hypothesized that it reflects calcified components. It may be associated with embolization from...

journal_title：Stroke

authors： Nedelmann M,Graef M,Weinand F,Wassill KH,Kaps M,Lorenz B,Tanislav C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hetereothermic mammals tolerate hypoxia during euthermy and torpor, and evidence suggests this tolerance may extend beyond hypoxia to cerebral ischemia. During hibernation, CA1 hippocampal neurons endure extreme fluctuations in cerebral blood flow during transitions into and out of torpor as well...

journal_title：Stroke

authors： Dave KR,Prado R,Raval AP,Drew KL,Perez-Pinzon MA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of the present study is to determine the effect of mild hypothermia on the synthesis of ubiquitin, an important protein for maintenance of cell viability, in the hippocampal neurons following transient cerebral ischemia. METHODS:Transient ischemia was induced by occluding both common...

journal_title：Stroke

authors： Yamashita K,Eguchi Y,Kajiwara K,Ito H

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animals, drugs that increase brain amine concentrations influence the rate and degree of recovery from cortical lesions. It is therefore conceivable that antidepressants may influence outcome after ischemic brain injury in humans. We evaluated the effects of the norepinephrine reuptake blocker...

journal_title：Stroke

authors： Dam M,Tonin P,De Boni A,Pizzolato G,Casson S,Ermani M,Freo U,Piron L,Battistin L

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cannabidiol has been reported to be a neuroprotectant, but the neuroprotective mechanism of cannabidiol remains unclear. We studied the neuroprotective mechanism of cannabidiol in 4-hour middle cerebral artery (MCA) occlusion mice. METHODS:Male MCA occluded mice were treated with cannabidiol, ab...

journal_title：Stroke

authors： Mishima K,Hayakawa K,Abe K,Ikeda T,Egashira N,Iwasaki K,Fujiwara M

更新日期：2005-05-01 00:00:00

abstract：:Background and Purpose- The CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) demonstrated equivalent composite outcomes between carotid endarterectomy (CEA) and carotid artery stenting (CAS) for treating carotid stenosis. We investigated nationwide trends in these procedures and associated peripr...

journal_title：Stroke

authors： Cole TS,Mezher AW,Catapano JS,Godzik J,Baranoski JF,Nakaji P,Albuquerque FC,Lawton MT,Little AS,Ducruet AF

更新日期：2020-02-01 00:00:00

abstract：:The reactivity of cerebral blood vessels to changes in PaCO2 in areas of the cerebral cortex with or without diaschisis was investigated in 13 patients in a subacute or chronic stage after a small capsular infarct. A focal area of hypoperfusion (area of diaschisis) was detected in the ipsilateral sensorimotor cortex i...

journal_title：Stroke

authors： Takano T,Nagatsuka K,Ohnishi Y,Takamitsu Y,Matsuo H,Matsumoto M,Kimura K,Kamada T

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Specialized management of patients with stroke is not available in all hospitals. We evaluated whether prehospital management in the Stroke Emergency Mobile (STEMO) improves the triage of patients with stroke. METHODS:STEMO is an ambulance staffed with a specialized stroke team and equipped with...

journal_title：Stroke

authors： Wendt M,Ebinger M,Kunz A,Rozanski M,Waldschmidt C,Weber JE,Winter B,Koch PM,Freitag E,Reich J,Schremmer D,Audebert HJ,STEMO Consortium.

更新日期：2015-03-01 00:00:00

abstract：:We tested the reproducibility of consecutive measurements of regional cerebral blood flow (rCBF) made in 13 areas of each hemisphere in patients with cerebrovascular diseases by the atraumatic 133Xe intravenous injection method. The data were analysed by a two-compartment model similar to that used in the Obrist inhal...

journal_title：Stroke

authors： Meric P,Luft A,Seylaz J,Mamo H

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A previous study suggested that occlusive diseases of small penetrating arteries account for most anterior choroidal artery (AChA) territory infarcts, but half of the patients did not have an echocardiogram. Cases of AChA territory infarcts associated with internal carotid artery stenosis or atri...

journal_title：Stroke

authors： Leys D,Mounier-Vehier F,Lavenu I,Rondepierre P,Pruvo JP

更新日期：1994-04-01 00:00:00

abstract：:Radiolabelled misonidazole, a radiosensitizing drug that binds to viable hypoxic tumor cells, may be useful in identifying hypoxic cells in cerebrovascular disease. Its potential was investigated in the gerbil stroke model. Biodistribution of [3H]misonidazole was measured in normal gerbils and animals that had been su...

journal_title：Stroke

authors： Hoffman JM,Rasey JS,Spence AM,Shaw DW,Krohn KA

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Early neurological deterioration (END) occurs in ≥20% of single small subcortical infarctions (SSSIs; axial diameter ≤20 mm in the perforator territories) and deters functional recovery. Both microvasculopathies and atherosclerosis have been proposed to independently contribute to the occurrence ...

journal_title：Stroke

authors： Jeong HG,Kim BJ,Yang MH,Han MK,Bae HJ

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microwave Radiometry (MWR) allows in vivo noninvasive assessment of internal temperature of tissues. The aim of the present study was to evaluate in patients with ischemic stroke and bilateral carotid plaques (1) whether ipsilateral carotid arteries exhibit higher temperature differences (ΔT), as...

journal_title：Stroke

authors： Toutouzas K,Benetos G,Drakopoulou M,Deligianni C,Spengos K,Stefanadis C,Siores E,Tousoulis D

更新日期：2015-01-01 00:00:00

abstract：:Using the dexamethasone suppression test, we studied the activity of the hypothalamic-pituitary-adrenal axis within the first week after onset in 62 patients with acute ischemic stroke. Compared with two control groups (one comprising 25 elderly patients with various acute medical disorders and the other comprising 33...

journal_title：Stroke

authors： Olsson T,Aström M,Eriksson S,Forssell A

更新日期：1989-12-01 00:00:00

abstract：:We studied the effects of the calcium channel blocker nicardipine on regional tissue Ca2+, Na+, K+, and water shifts in the brains of seven Sprague-Dawley rats after permanent occlusions of the middle cerebral artery. We also assessed the entry of [14C]nicardipine into the brains of five rats; the highest concentratio...

journal_title：Stroke

authors： Hadani M,Young W,Flamm ES

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Apolipoprotein E (apoE) epsilon 4 allele has been associated with a high risk for coronary heart disease. Increased frequency of the epsilon 4 allele has also been reported in patients with late-onset familial and sporadic Alzheimer's disease (AD). The aim of this study was to investigate the deg...

journal_title：Stroke

authors： Kosunen O,Talasniemi S,Lehtovirta M,Heinonen O,Helisalmi S,Mannermaa A,Paljärvi L,Ryynänen M,Riekkinen PJ Sr,Soininen H

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The cerebrovascular contribution to ischemic preconditioning (IPC) has been scarcely explored. Using in vivo and in vitro approaches, we investigated the involvement of the blood-brain barrier and the role of its cellular components. METHODS:Seven-minute occlusion of the right middle cerebral ar...

journal_title：Stroke

authors： Gesuete R,Orsini F,Zanier ER,Albani D,Deli MA,Bazzoni G,De Simoni MG

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our investigation sought to determine whether neonatal brain ischemic vascular and metabolic effects were altered by repeated episodes of ischemia. METHODS:We studied twelve piglets using in vivo magnetic resonance spectroscopy to obtain multiple, simultaneous measurements of cerebral blood flow...

journal_title：Stroke

authors： Laptook AR,Corbett RJ,Ruley J,Olivares E

更新日期：1992-03-01 00:00:00

abstract：:Background and Purpose- Intraluminal thrombus (ILT) is an uncommon finding among patients with ischemic stroke. We report clinical-imaging manifestations, treatment offered, and outcome among patients with ischemic stroke/transient ischemic attack and ILT in their cervico-cephalic arteries. Methods- Sixty-one of 3750 ...

journal_title：Stroke

authors： Singh RJ,Chakraborty D,Dey S,Ganesh A,Al Sultan AS,Eesa M,Wong JH,Goyal M,Hill MD,Menon BK

更新日期：2019-02-01 00:00:00