Does the mismatch match the penumbra? Magnetic resonance imaging and positron emission tomography in early ischemic stroke.

abstract：BACKGROUND AND PURPOSE:Recent innovations such as CT installation in ambulances may lead to earlier start of stroke-specific treatments. However, such technically complex mobile facilities require effective methods of correctly identifying patients before deployment. We aimed to develop and validate a new dispatcher id...

journal_title：Stroke

authors： Krebes S,Ebinger M,Baumann AM,Kellner PA,Rozanski M,Doepp F,Sobesky J,Gensecke T,Leidel BA,Malzahn U,Wellwood I,Heuschmann PU,Audebert HJ

更新日期：2012-03-01 00:00:00

abstract：:Cerebral cortical blood flow was measured in rabbits with the hydrogen clearance technique. The reactivity to CO2, tested by changing the end tidal CO2 (ETCO2) in steps from 2 to 6 volumes %, was highly dependent on the kind of anesthesia, being greatest under halothane and least under nitrous oxide. Reactivity to CO2...

journal_title：Stroke

authors： Scremin OU,Rubinstein EH,Sonnenschein RR

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of these experiments was to examine mechanisms by which hypercapnia produces vasodilatation in brain. We examined the hypothesis that dilatation of cerebral arterioles during hypercapnia is dependent on activation of ATP-sensitive potassium channels and formation of nitric oxide. MET...

journal_title：Stroke

authors： Faraci FM,Breese KR,Heistad DD

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lower concentrations of albumin have been positively related to coronary disease. The aim of this project was to assess the association between serum albumin and carotid atherosclerosis. METHODS:B-mode ultrasound was used to assess carotid plaques and intima-media thickness (IMT) among white sub...

journal_title：Stroke

authors： Djoussé L,Rothman KJ,Cupples LA,Arnett DK,Ellison RC,NHLBI Family Heart Study.

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Victims of air embolism often recover rapidly on hyperbaric treatment then deteriorate again, even if hyperbaric treatment is continued. In previous animal experiments, lidocaine has been shown to improve recovery of somatosensory evoked response amplitude after air embolism. However, animals in ...

journal_title：Stroke

authors： Dutka AJ,Mink R,McDermott J,Clark JB,Hallenbeck JM

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to identify variables associated with intracerebral hemorrhage in patients with acute ischemic stroke who receive tissue plasminogen activator (t-PA). METHODS:We performed subgroup analyses of data from a randomized, double-blind, placebo-controlled trial of intravenous t-PA administer...

journal_title：Stroke

authors：

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction. We aimed to determine which baseline clinical and radiological parameters predict development of CED in patients treated with...

journal_title：Stroke

authors： Thorén M,Azevedo E,Dawson J,Egido JA,Falcou A,Ford GA,Holmin S,Mikulik R,Ollikainen J,Wahlgren N,Ahmed N

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The neuroprotective role of mild therapeutic hypothermia was established in animal models of cerebral ischemia. Still, several issues, including optimal target temperature, remain unclear. The optimal depth of hypothermia in a rat model of focal cerebral ischemia was investigated. METHODS:Eighty...

journal_title：Stroke

authors： Kollmar R,Blank T,Han JL,Georgiadis D,Schwab S

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) and carotid duplex (CD) provide rapid and safe screening for stroke patients but are highly operator dependent. We explored the feasibility of telemedicine (TM)-guided TCD/CD administered by a health care provider inexperienced with ultrasound. METHODS:Dual video scree...

journal_title：Stroke

authors： Mikulik R,Alexandrov AV,Ribo M,Garami Z,Porche NA,Fulep E,Grotta JC,Wojner-Alexandrov AW,Choi JY

更新日期：2006-01-01 00:00:00

abstract：:Reduction in cerebral blood flow (CBF) following global ischemia has been implicated as a pathogenetic mechanism in progressive brain damage seen after restoration of effective cardiac action and cerebral perfusion pressure. There are serious limitations to many of the techniques for measuring regional cerebral blood ...

journal_title：Stroke

authors： Jackson DL,Dole WP,McGloin J,Rosenblatt JI

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to clarify whether mitral valve prolapse increases the subsequent risk of stroke. METHODS:A historical cohort study was conducted on 1079 residents of Olmsted County, Minnesota, who had an initial echocardiographic diagnosis of mitral valve prolapse between 1975 and...

journal_title：Stroke

authors： Orencia AJ,Petty GW,Khandheria BK,Annegers JF,Ballard DJ,Sicks JD,O'Fallon WM,Whisnant JP

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Arterial stiffness is associated with an increased risk of myocardial infarction and stroke, independent of classical vascular risk factors. Vascular factors and stroke are associated with cognitive function and dementia. We examined whether arterial stiffness was independently associated with co...

journal_title：Stroke

authors： Poels MM,van Oijen M,Mattace-Raso FU,Hofman A,Koudstaal PJ,Witteman JC,Breteler MM

更新日期：2007-03-01 00:00:00

abstract：:Weights of matching right and left middle or posterior cerebral arteries and their main branches from the same animal were compared 8-10 weeks after unilateral denervation by superior cervical ganglionectomy. When compared in pairs, the denervated arterial systems weighed significantly less (mean 85%) than their inner...

journal_title：Stroke

authors： Bevan RD,Tsuru H,Bevan JA

更新日期：1983-05-01 00:00:00

abstract：:The Stenting and Aggressive Medical Management for Preventing Recurrent Stroke and Intracranial Stenosis (SAMMPRIS) trial, a randomized clinical trial comparing aggressive medical management to stenting with aggressive medical management for symptomatic intracranial stenosis, was prematurely halted when a high rate of...

journal_title：Stroke

authors： Marks MP

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to validate the diagnosis of self-reported stroke. METHODS:During 1994-1995, 27 159 people attended a population health survey in the community of Tromso, Norway, a response rate of 77%. A total of 418 attenders reported a history of stroke. In 1997, all individuals wit...

journal_title：Stroke

authors： Engstad T,Bonaa KH,Viitanen M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autonomic dysfunction, including increased sympathetic drive and blunted baroreflex, has repeatedly been observed in acute stroke. Of clinical importance is that the stroke-related autonomic imbalance seems to be linked to worse outcome after stroke. Here, we discuss the role of baroreflex impair...

journal_title：Stroke

authors： Sykora M,Diedler J,Turcani P,Hacke W,Steiner T

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thick cisternal clot on CT is a well-recognized risk factor for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH). Whether intraventricular hemorrhage (IVH) or intracerebral hemorrhage (ICH) predisposes to DCI is unclear. The Fisher CT grading scale identifies thick SAH but does...

journal_title：Stroke

authors： Claassen J,Bernardini GL,Kreiter K,Bates J,Du YE,Copeland D,Connolly ES,Mayer SA

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated urinary albumin excretion (UAE) is associated with an increased carotid intima-media thickness (IMT). Because angiotensin-converting enzyme inhibitors as well as statins have been shown to lower UAE and the progression of IMT, we assessed the effects of fosinopril and pravastatin on caro...

journal_title：Stroke

authors： Asselbergs FW,van Roon AM,Hillege HL,de Jong PE,Gans RO,Smit AJ,van Gilst WH,PREVEND IT Investigators.

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic stroke has a strong familial component to risk. The Siblings With Ischemic Stroke Study (SWISS) is a genome-wide, family-based analysis that included use of imputed genotypes. The Siblings With Ischemic Stroke Study was conducted to examine the associations between single-nucleotide poly...

journal_title：Stroke

authors： Meschia JF,Nalls M,Matarin M,Brott TG,Brown RD Jr,Hardy J,Kissela B,Rich SS,Singleton A,Hernandez D,Ferrucci L,Pearce K,Keller M,Worrall BB,Siblings With Ischemic Stroke Study Investigators.

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Conventional diets may cause hyperglycemia in patients with neurological injuries. The purpose of this study was to examine the effect on the severity of cerebral infarction of replacing carbohydrates as the primary dietary source of nonprotein calories. METHODS:Sixty-nine Long-Evans rats were e...

journal_title：Stroke

authors： Robertson C,Goodman JC,Grossman RG,Claypool M,White A

更新日期：1992-04-01 00:00:00

abstract：:Thrombus formation is of paramount importance in the pathophysiology of acute ischemic stroke. Current antithrombotics used to treat or prevent cerebral ischemia are only moderately effective or bear an increased risk of severe bleeding. von Willebrand factor (VWF) has long been known to be a key player in thrombus fo...

journal_title：Stroke

authors： De Meyer SF,Stoll G,Wagner DD,Kleinschnitz C

更新日期：2012-02-01 00:00:00

abstract：:The nature of alpha-adrenergic receptors in human cerebral arteries was characterized, and alteration of these receptors after subarachnoid hemorrhage was examined using a radioligand binding assay. Norepinephrine content of control arteries was also analyzed and compared with that of arteries after subarachnoid hemor...

journal_title：Stroke

authors： Tsukahara T,Taniguchi T,Miwa S,Shimohama S,Fujiwara M,Nishikawa M,Handa H

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In a previous study, we occasionally found that the rat given naloxone in the preoptic region develops behavioral seizures. In view of knowledge that the forebrain including the medial septal nucleus provides cholinergic projections to the hippocampal formation, the present study examined the eff...

journal_title：Stroke

authors： Nishimura J,Endo Y,Kimura F

更新日期：1992-09-01 00:00:00

abstract：:Background and Purpose- Although older age is one of the most important risk factor for stroke in atrial fibrillation (AF), the appropriate age threshold (eg, CHA2DS2-VASc score [congestive heart failure, hypertension, age ≥75 years (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vas...

journal_title：Stroke

authors： Kim TH,Yang PS,Yu HT,Jang E,Uhm JS,Kim JY,Pak HN,Lee MH,Joung B,Lip GYH

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Reduced arterial distensibility has been introduced as a novel risk factor for atherosclerosis. The importance of the genetic contribution to variation in distensibility is largely unknown. The purpose of this study was to estimate heritability of carotid distensibility. METHODS:The ongoing Nort...

journal_title：Stroke

authors： Juo SH,Rundek T,Lin HF,Cheng R,Lan MY,Huang JS,Boden-Albala B,Sacco RL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clomethiazole is a neuroprotective drug that enhances gamma-aminobutyrate type A (GABA(A)) receptor activity. Its efficacy and safety were tested in the CLomethiazole Acute Stroke Study (CLASS). The protocol allowed a CT scan to be done after randomization but within 7 days of stroke onset to min...

journal_title：Stroke

authors： Wahlgren NG,Díez-Tejedor E,Teitelbaum J,Arboix A,Leys D,Ashwood T,Grossman E

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Unaccustomed strenuous physical exertion can trigger myocardial infarction, but little is known about the mechanisms precipitating subarachnoid hemorrhage (SAH). METHODS:We identified all cases of first-ever SAH among the combined populations (2.8 million) of 4 urban centers in Australia and New...

journal_title：Stroke

authors： Anderson C,Ni Mhurchu C,Scott D,Bennett D,Jamrozik K,Hankey G,Australasian Cooperative Research on Subarachnoid Hemorrhage Study Group.

更新日期：2003-07-01 00:00:00

abstract：:Background and Purpose- Mobile Stroke Units (MSUs) provide innovative prehospital stroke care but their 24/7 operation has not been studied. Our study investigates 24/7 MSU diurnal variations related to transport frequency, patient characteristics, and stroke treatments. Methods- We compared transportation frequency, ...

journal_title：Stroke

authors： Zaidat OO,Changal KH,Sultan-Qurraie A,de Havenon A,Calderon VJ,Goins-Whitmore J,Patterson MS,Lin E

更新日期：2019-07-01 00:00:00

abstract：:Eighty-one young Japanese patients with occlusive thromboaortopathy (Takayasu's disease) were classed into three groups according to the degree and extent of diameter stenosis in the 4 cervical arterial systems, as determined by serial aortography. Class I was made up of 63 patients with 70% or greater stenosis in les...

journal_title：Stroke

authors： Ishikawa K,Uyama M,Asayama K

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) after stroke increases risk of hemorrhagic transformation, particularly in areas with blood-brain barrier leakage. Our aim was to characterize acute effects of rtPA administration on the integrity of microvascular barriers....

journal_title：Stroke

authors： Dijkhuizen RM,Asahi M,Wu O,Rosen BR,Lo EH

更新日期：2002-08-01 00:00:00