Stroke associated with antiphospholipid antibodies.

abstract：BACKGROUND AND PURPOSE:There are uncertainties surrounding the optimal management of patients with brain swelling after an ischemic stroke. Guidelines are needed on how to manage this major complication, how to provide the best comprehensive neurological and medical care, and how to best inform families facing complex ...

journal_title：Stroke

authors： Wijdicks EF,Sheth KN,Carter BS,Greer DM,Kasner SE,Kimberly WT,Schwab S,Smith EE,Tamargo RJ,Wintermark M,American Heart Association Stroke Council.

更新日期：2014-04-01 00:00:00

abstract：:Background and Purpose- Patients with intracerebral hemorrhage (ICH) and atrial fibrillation (AF) are at risk for ischemic events. While risk calculators (CHA2DS2-VASc and HAS-BLED) have been validated to assess risk for ischemic stroke and major bleeding in AF patients, decisions about anticoagulation must consider t...

journal_title：Stroke

authors： Stanton RJ,Eckman MH,Woo D,Moomaw CJ,Haverbusch M,Flaherty ML,Kleindorfer DO

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Proinflammatory cytokines including interleukin-6 (IL-6) are supposed to play a pivotal role in the development of atherosclerosis. A common polymorphism in the promoter of the IL-6 gene (IL-6 -174G>C) affects plasma IL-6 concentrations and has been suggested as a risk factor for cardiovascular d...

journal_title：Stroke

authors： Weger M,Steinbrugger I,Haas A,März W,El-Shabrawi Y,Weger W,Schmut O,Renner W

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The benefits of chronic disease self-management programs for stroke survivors are uncertain because individuals with severe impairments have been excluded from previous research. We undertook a phase II randomized controlled trial to determine whether a self-management program designed for surviv...

journal_title：Stroke

authors： Cadilhac DA,Hoffmann S,Kilkenny M,Lindley R,Lalor E,Osborne RH,Batterbsy M

更新日期：2011-06-01 00:00:00

abstract：:Survival and recurrences after stroke were assessed prospectively in a general population sample of 5184 subjects followed biennially for 26 years. Initial strokes occurred in 198 men and 196 women. There were 84 second and 27 third strokes and 223 deaths reported. Thirty day case-fatality rates for initial strokes we...

journal_title：Stroke

authors： Sacco RL,Wolf PA,Kannel WB,McNamara PM

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The primary purpose of intracranial aneurysm treatment is to prevent rupture. Risk factors for rupture after aneurysm treatment have not been clearly established, and the need to completely occlude aneurysms is debated. METHODS:The Cerebral Aneurysm Rerupture After Treatment (CARAT) study is an ...

journal_title：Stroke

authors： Johnston SC,Dowd CF,Higashida RT,Lawton MT,Duckwiler GR,Gress DR,CARAT Investigators.

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It was found that glutamate, a major neurotransmitter, is vasoactive in the cerebral circulation. However, the mechanism is unclear. This study was designed to investigate the role of nitric oxide (NO) and N-methyl-D-aspartate (NMDA) receptors in cerebral arteriolar dilation to glutamate. METHOD...

journal_title：Stroke

authors： Meng W,Tobin JR,Busija DW

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Magnetic resonance perfusion (MRP) and computed tomographic perfusion (CTP) are being increasingly applied in acute stroke trials and clinical practice, yet the comparability of their perfusion values is not well validated. The aim of this study was to validate the comparability of CTP and MRP me...

journal_title：Stroke

authors： Lin L,Bivard A,Levi CR,Parsons MW

更新日期：2014-06-01 00:00:00

abstract：:Cerebral ischemic events associated with arteriography are usually attributed to catheter-induced emboli. We present three patients with cerebral ischemia occurring 6 to 48 hours post-arteriography. We suspected that alternate pathogenic mechanisms were in effect. To evaluate the possibility that sustained platelet ac...

journal_title：Stroke

authors： Fisher M,Sandler R,Weiner JM

更新日期：1985-05-01 00:00:00

abstract：:As part of a prospective study of the neurologic and neuropsychological complications of coronary artery bypass graft surgery, 312 patients were compared with a control group of 50 patients undergoing major surgery for peripheral vascular disease. The purpose of comparing the 2 groups was to determine to what extent n...

journal_title：Stroke

authors： Shaw PJ,Bates D,Cartlidge NE,French JM,Heaviside D,Julian DG,Shaw DA

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron overload has been associated with greater oxidative stress and brain injury in experimental cerebral ischemia and reperfusion. This study investigates whether high serum ferritin levels, as an index of increased cellular iron stores, are associated with poor outcome, hemorrhagic transformati...

journal_title：Stroke

authors： Millan M,Sobrino T,Castellanos M,Nombela F,Arenillas JF,Riva E,Cristobo I,García MM,Vivancos J,Serena J,Moro MA,Castillo J,Dávalos A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Silent cerebrovascular disease (CVD) has been proposed as a predisposing condition for clinically overt stroke and vascular dementia. Recently, we found increased thrombin generation in silent CVD patients. Here, we report the effect of thrombin inhibition using a potent selective thrombin inhibi...

journal_title：Stroke

authors： Kario K,Matsuo T,Hoshide S,Umeda Y,Shimada K

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains unknown whether the effects of 0.6 mg/kg alteplase differ with occlusion site of the middle cerebral artery (MCA). We therefore evaluated the effects of 0.6 mg/kg intravenous alteplase in patients with different sites of MCA occlusion. METHODS:An exploratory analysis was made of 57 pa...

journal_title：Stroke

authors： Hirano T,Sasaki M,Mori E,Minematsu K,Nakagawara J,Yamaguchi T,Japan Alteplase Clinical Trial II Group.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Experimental and clinical data suggest that insonation of echo-contrast agents with high acoustical power produces disintegration of microbubbles, resulting in a pseudo-Doppler phenomenon called stimulated acoustic emission (SAE). The purpose of this study was to investigate whether SAE might be ...

journal_title：Stroke

authors： Pohl C,Tiemann K,Schlosser T,Becher H

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Neuroradiological characteristics and functional outcomes of patients with intracerebral hemorrhage (ICH) during novel oral anticoagulant treatment were not well defined. We examined these in comparison with those during warfarin treatment. METHODS:The consecutive 585 patients with ICH admitted ...

journal_title：Stroke

authors： Hagii J,Tomita H,Metoki N,Saito S,Shiroto H,Hitomi H,Kamada T,Seino S,Takahashi K,Baba Y,Sasaki S,Uchizawa T,Iwata M,Matsumoto S,Osanai T,Yasujima M,Okumura K

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains uncertain whether lower dose intravenous tissue-type plasminogen activator (tPA) for stroke is as effective and safe as the standard dose. METHODS:We analyzed data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China). Patients who were treate...

journal_title：Stroke

authors： Liao X,Wang Y,Pan Y,Wang C,Zhao X,Wang DZ,Wang C,Liu L,Wang Y,Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China Investigators.

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Brain microbleeds (MBs) are considered to be associated with cognitive decline and can be pathologically and topographically classified as cerebral amyloid angiopathy-related (located in lobar regions) and hypertensive microangiopathy-related (located in deep regions). We examined whether differe...

journal_title：Stroke

authors： Yakushiji Y,Noguchi T,Hara M,Nishihara M,Eriguchi M,Nanri Y,Nishiyama M,Hirotsu T,Nakajima J,Kuroda Y,Hara H

更新日期：2012-07-01 00:00:00

abstract：:We investigated the effects of phenytoin on the rate of enzymatic release of free fatty acids and on the levels of energy metabolites and nucleoside phosphates in ischemic brain. Phenytoin (10 mg/kg i.v.) was administered 30 minutes before the onset of ischemia induced in 30 male Wistar rats by occluding the basilar a...

journal_title：Stroke

authors： Kinouchi H,Imaizumi S,Yoshimoto T,Motomiya M

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy. METHODS:We categorized 71 patients ...

journal_title：Stroke

authors： Jung YH,Jang H,Park SB,Choe YS,Park Y,Kang SH,Lee JM,Kim JS,Kim J,Kim JP,Kim HJ,Na DL,Seo SW

更新日期：2020-12-01 00:00:00

abstract：:Seventy-four patients with hypertensive putaminal hemorrhage (HPH) were followed at least 6 months after treatment and estimated by ADL. They were graded according to the state of consciousness on admission. The grading consists of 6 grades: Grade 1, fully conscious; Grade 2, somnolent; Grade 3, stuporous; Grade 4, se...

journal_title：Stroke

authors： Waga S,Yamamoto Y

更新日期：1983-07-01 00:00:00

abstract：:Non-invasive ultrasonic imaging of the carotid bifurcation by duplex scanning and ultrasonic arteriography combined with pulsed Doppler spectrum analysis demonstrated patency of the external and internal carotid arteries distal to a common carotid occlusion in 3 patients. Common carotid occlusion is not invariably ass...

journal_title：Stroke

authors： Blackshear WM Jr,Phillips DJ,Bodily KC,Strandness DE Jr

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The extent of cardiac investigation required in patients with coexistent symptomatic carotid and cardiac disease is unsettled. This study compared the outlook for patients symptomatic from carotid stenosis with and without a history of symptomatic ischemic heart disease (IHD). METHODS:The risk o...

journal_title：Stroke

authors： Gates PC,Eliasziw M,Algra A,Barnett HJ,Gunton RW,North American Symptomatic Carotid Endarterectomy Trial Group.

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of the sympathetic nervous system in cerebral autoregulation remains poorly characterized. We examined cerebral blood flow responses to augmented arterial pressure oscillations with and without sympathetic blockade and compared them with responses in the forearm circulation. METHODS:An ...

journal_title：Stroke

authors： Hamner JW,Tan CO,Lee K,Cohen MA,Taylor JA

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The incidence, causes, and prognosis of nonhemorrhagic strokes and intraparenchymal hemorrhages occurring in association with pregnancy or puerperium are poorly understood. METHODS:We carried out a retrospective (1989 through 1991) and prospective (1992) study in 63 public maternities (348,295 d...

journal_title：Stroke

authors： Sharshar T,Lamy C,Mas JL

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Striatal GABAergic neuron is known as a key regulator in adult neurogenesis. However, the specific role of striatal GABAergic neuronal activity in the promotion of neurological recovery after ischemic stroke remains unknown. Here, we used optogenetic approach to investigate these effects and mech...

journal_title：Stroke

authors： Jiang L,Li W,Mamtilahun M,Song Y,Ma Y,Qu M,Lu Y,He X,Zheng J,Fu Z,Zhang Z,Yang GY,Wang Y

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The epsilon4 allele of the apolipoprotein E (apoE) has been related to the occurrence of myocardial infarction, but its association with ischemic stroke is controversial. We have evaluated the relation between apoE alleles and the occurrence of cerebrovascular ischemia. METHODS:The apoE epsilon ...

journal_title：Stroke

authors： Margaglione M,Seripa D,Gravina C,Grandone E,Vecchione G,Cappucci G,Merla G,Papa S,Postiglione A,Di Minno G,Fazio VM

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the modified Rankin Scale (mRS) is the most commonly used primary end point in acute stroke trials, its power is limited when analyzed in dichotomized fashion and its indication of effect size challenging to interpret when analyzed ordinally. Weighting the 7 Rankin levels by utilities ma...

journal_title：Stroke

authors： Chaisinanunkul N,Adeoye O,Lewis RJ,Grotta JC,Broderick J,Jovin TG,Nogueira RG,Elm JJ,Graves T,Berry S,Lees KR,Barreto AD,Saver JL,DAWN Trial and MOST Trial Steering Committees.,Additional contributors from DAWN Trial Steering

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial direct current stimulation is emerging as a promising tool for the treatment of several neurological conditions, including cerebral ischemia. The therapeutic role of this noninvasive treatment is, however, limited to chronic phases of stroke. We thus ought to investigate whether diff...

journal_title：Stroke

authors： Peruzzotti-Jametti L,Cambiaghi M,Bacigaluppi M,Gallizioli M,Gaude E,Mari S,Sandrone S,Cursi M,Teneud L,Comi G,Musco G,Martino G,Leocani L

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Abnormalities in endogenous fibrinolysis are associated with an increased risk for stroke in men and older adults. We tested the hypothesis that elevated plasma tissue plasminogen activator (tPA) antigen, a marker for impaired endogenous fibrinolysis, is an independent risk factor for stroke in y...

journal_title：Stroke

authors： Macko RF,Kittner SJ,Epstein A,Cox DK,Wozniak MA,Wityk RJ,Stern BJ,Sloan MA,Sherwin R,Price TR,McCarter RJ,Johnson CJ,Earley CJ,Buchholz DW,Stolley PD

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In an inner-London teaching hospital, a randomized trial of "conventional" care versus early discharge to community-based therapy found no significant differences in clinical outcomes between patient groups. This report examines the economic consequences of the alternative strategies. METHODS:On...

journal_title：Stroke

authors： Beech R,Rudd AG,Tilling K,Wolfe CD

更新日期：1999-04-01 00:00:00