Changes of neural activity correlate with the severity of cortical ischemia in patients with unilateral major cerebral artery occlusion.

abstract：:Background and Purpose- Intracerebral hemorrhage (ICH) has a poorer prognosis than acute ischemic stroke (AIS). However, clinician perception of prognosis may influence treatment decisions and adversely affect outcome. On acute CT, the conspicuity of ICH compared with AIS may lead clinicians to overestimate severity a...

journal_title：Stroke

authors： Tilling EJ,El Tawil S,Muir KW

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recovery from hemiparesis due to corticospinal tract infarction is well documented, but the mechanism of recovery is unknown. Functional MRI (fMRI) provides a means of identifying focal brain activity related to movement of a paretic hand. Although prior studies have suggested that supplementary ...

journal_title：Stroke

authors： Marshall RS,Perera GM,Lazar RM,Krakauer JW,Constantine RC,DeLaPaz RL

更新日期：2000-03-01 00:00:00

abstract：:The effects of halothane on intracellular membrane potential (Em) and force development in cat MCA were studied. Halothane (0.07-0.14 mM/1) relaxed isolated MCA which had developed myogenic tone. Measurement of Em showed that halothane depolarized this preparation in a dose-dependent fashion in the face of vessel rela...

journal_title：Stroke

authors： Harder DR,Gradall K,Madden JA,Kampine JP

更新日期：1985-07-01 00:00:00

abstract：:Background and Purpose- Intracranial thrombi can be characterized according to their permeability as measured by contrast agent penetration. Thrombus composition and its associated pathogenesis are important factors affecting treatment and secondary prevention. We aimed to explore the histopathologic factors explainin...

journal_title：Stroke

authors： Berndt M,Friedrich B,Maegerlein C,Moench S,Hedderich D,Lehm M,Zimmer C,Straeter A,Poppert H,Wunderlich S,Schirmer L,Oberdieck P,Kaesmacher J,Boeckh-Behrens T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid endarterectomy is an effective method for preventing strokes if patients do not suffer adverse perioperative outcomes. The purpose of this study was to identify preoperative patient risk factors for adverse outcomes (death or nonfatal stroke) after carotid endarterectomy through the use o...

journal_title：Stroke

authors： Tu JV,Wang H,Bowyer B,Green L,Fang J,Kucey D,Participants in the Ontario Carotid Endarterectomy Registry.

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron overload has been associated with greater oxidative stress and brain injury in experimental cerebral ischemia and reperfusion. This study investigates whether high serum ferritin levels, as an index of increased cellular iron stores, are associated with poor outcome, hemorrhagic transformati...

journal_title：Stroke

authors： Millan M,Sobrino T,Castellanos M,Nombela F,Arenillas JF,Riva E,Cristobo I,García MM,Vivancos J,Serena J,Moro MA,Castillo J,Dávalos A

更新日期：2007-01-01 00:00:00

abstract：:In a consecutive series of 473 patients admitted within 72 hours after a subarachnoid hemorrhage, 91 (19%) had hydrocephalus on the initial computed tomogram. Consciousness was unimpaired in 25 of the 91 (28%). In 11 more patients acute hydrocephalus developed within 1 week after subarachnoid hemorrhage. Thirty-eight ...

journal_title：Stroke

authors： Hasan D,Vermeulen M,Wijdicks EF,Hijdra A,van Gijn J

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Priorities in the care of stroke patients are often intuitive. An open and translucent priority-setting procedure would benefit patients, professionals, and decision-makers. Prioritization is an innovative part of the new Swedish national stroke guidelines. METHODS:Working groups identified diag...

journal_title：Stroke

authors： Norrving B,Wester P,Sunnerhagen KS,Terént A,Sohlberg A,Berggren F,Wester PO,Asplund K,Stroke Guidelines Working Group, National Board of Health and Welfare, Stockholm, Sweden.

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We designed a prospective sequential pretreatment and posttreatment MRI study to assess the relation between neuroimaging parameters and clinical outcome in patients treated with intravenous recombinant tissue-type plasminogen activator (rtPA). METHODS:Patients with symptoms of acute hemispheric...

journal_title：Stroke

authors： Nighoghossian N,Hermier M,Adeleine P,Derex L,Dugor JF,Philippeau F,Ylmaz H,Honnorat J,Dardel P,Berthezène Y,Froment JC,Trouillas P

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous work has shown that rates of cerebral microemboli downstream of high-grade internal carotid artery stenosis are higher in recently symptomatic compared with asymptomatic patients. In addition, microembolic rates decline after carotid endarterectomy. We conducted a prospective investigati...

journal_title：Stroke

authors： Sitzer M,Müller W,Siebler M,Hort W,Kniemeyer HW,Jäncke L,Steinmetz H

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Obvious cardiac dysfunction, including ECG abnormalities and left ventricular asynergy, is known to develop after subarachnoid hemorrhage (SAH). To clarify the close relationship between myocardial damage and sympathetic nervous activity immediately after SAH, a novel experimental animal model wa...

journal_title：Stroke

authors： Masuda T,Sato K,Yamamoto S,Matsuyama N,Shimohama T,Matsunaga A,Obuchi S,Shiba Y,Shimizu S,Izumi T

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is evidence of unequal access to health care interventions even where universal health systems operate. We investigated associations between patients' sociodemographic characteristics and the provision of acute and longer-term stroke care in a multiethnic urban population. METHODS:We used ...

journal_title：Stroke

authors： McKevitt C,Coshall C,Tilling K,Wolfe C

更新日期：2005-02-01 00:00:00

abstract：:Four university centers collaborated to contribute 1158 patients with acute episodes of cerebrovascular disease to the pilot Stroke Data Bank, initiated by NINCDS in 1978. During the pilot project a standard set of data collection forms were developed and used at each of the collaborating centers. Data on clinical cou...

journal_title：Stroke

authors： Kunitz SC,Gross CR,Heyman A,Kase CS,Mohr JP,Price TR,Wolf PA

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Symptomatic hemorrhage contributes to an increased risk of repeated bleeding and morbidity in cerebral cavernous malformation (CCM). A better understanding of morbidity after CCM hemorrhage would be helpful to identify patients of higher risk for unfavorable outcome and tailor individualized mana...

journal_title：Stroke

authors： Ma L,Zhang S,Li Z,Wu CX,Wang Z,Zhan L,Hao Q,Wang H,Ye X,Chen X,Liu YO,Wang S,Zhao YL

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A simple method of testing cerebral autoregulation by observing transcranial Doppler changes in middle cerebral artery flow velocity (FV) during a brief ipsilateral carotid artery compression (the transient hyperemic response test) was studied in 11 normal healthy volunteers. The aim of this stud...

journal_title：Stroke

authors： Smielewski P,Czosnyka M,Kirkpatrick P,McEroy H,Rutkowska H,Pickard JD

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A ruptured intracranial aneurysm (IA) is the leading cause of a subarachnoid hemorrhage. This study seeks to define a specific gene whose mutation leads to disease. METHODS:More than 500 IA probands and 100 affected families were enrolled and clinically characterized. Whole exome sequencing was ...

journal_title：Stroke

authors： Santiago-Sim T,Fang X,Hennessy ML,Nalbach SV,DePalma SR,Lee MS,Greenway SC,McDonough B,Hergenroeder GW,Patek KJ,Colosimo SM,Qualmann KJ,Hagan JP,Milewicz DM,MacRae CA,Dymecki SM,Seidman CE,Seidman JG,Kim DH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Most previous studies addressed the cognitive impact of lacunar infarcts using radiologic correlations that are known to correlate poorly with neuropathological data. Moreover, absence of systematic bilateral assessment of vascular lesions and masking effects of Alzheimer disease pathology and ma...

journal_title：Stroke

authors： Gold G,Kövari E,Herrmann FR,Canuto A,Hof PR,Michel JP,Bouras C,Giannakopoulos P

更新日期：2005-06-01 00:00:00

abstract：:Various studies indicate that after a latent interval, a progressive focal deterioration of microvascular perfusion can develop in zones of acute damage to the central nervous system (CNS). In order to obtain reliable information concerning the possibility of platelet participation in this phenomenon, platelet deposit...

journal_title：Stroke

authors： Obrenovitch TP,Hallenbeck JM

更新日期：1985-03-01 00:00:00

abstract：:Cerebral cortical blood flow was measured in rabbits with the hydrogen clearance technique. The reactivity to CO2, tested by changing the end tidal CO2 (ETCO2) in steps from 2 to 6 volumes %, was highly dependent on the kind of anesthesia, being greatest under halothane and least under nitrous oxide. Reactivity to CO2...

journal_title：Stroke

authors： Scremin OU,Rubinstein EH,Sonnenschein RR

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To test the safety and recanalization efficacy of intra-arterial local delivery of plasminogen activators in acute ischemic stroke, a randomized trial of recombinant pro-urokinase (rpro-UK) versus placebo was undertaken in patients with angiographically documented proximal middle cerebral artery ...

journal_title：Stroke

authors： del Zoppo GJ,Higashida RT,Furlan AJ,Pessin MS,Rowley HA,Gent M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To define desirable target low-density lipoprotein (LDL) cholesterol levels for the prevention of stroke recurrence, a post hoc analysis was performed in the J-STARS study (Japan Statin Treatment Against Recurrent Stroke). METHODS:Subjects (n=1578) were divided into groups based on mean value of...

journal_title：Stroke

authors： Hosomi N,Kitagawa K,Nagai Y,Nakagawa Y,Aoki S,Nezu T,Kagimura T,Maruyama H,Origasa H,Minematsu K,Uchiyama S,Matsumoto M,J-STARS Collaborators.

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelium-derived hyperpolarizing factor (EDHF)-mediated dilations are potentiated after several pathologies, including ischemia/reperfusion (I/R). However, no study to date has addressed the mechanism by which this potentiation occurs. This study tested the hypothesis that potentiated EDHF-med...

journal_title：Stroke

authors： Marrelli SP

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed cerebral ischemia and infarction due to reduced CBF remains the leading cause of poor outcome after aneurysmal subarachnoid hemorrhage. Hypertonic saline (HS) is associated with an increase in CBF. This study explores whether CBF enhancement with HS in patients with poor-grade subarachnoi...

journal_title：Stroke

authors： Al-Rawi PG,Tseng MY,Richards HK,Nortje J,Timofeev I,Matta BF,Hutchinson PJ,Kirkpatrick PJ

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The best management of patients with unruptured brain arteriovenous malformations (BAVM) is controversial. In this study, we analyzed the stroke rate and functional outcomes of patients having stereotactic radiosurgery (SRS) for unruptured BAVM using the same eligibility criteria and primary end ...

journal_title：Stroke

authors： Pollock BE,Link MJ,Brown RD

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Cardiac involvement in Whipple's disease is not an uncommon phenomenon in autopsies, but its clinical occurrence is often overshadowed by gastrointestinal symptoms. We report a very atypical manifestation of this disorder. SUMMARY OF REPORT:An extraordinary presentation of an extremely long-lasting, culture...

journal_title：Stroke

authors： Naegeli B,Bannwart F,Bertel O

更新日期：2000-08-01 00:00:00

abstract：:We have investigated the effects of a reduced regional or a reduced body temperature, on pial arteriolar response to a variety of vasoactive stimuli. This has been done by studying the effects of these stimuli on groups of mice with different body temperatures, or with different temperatures of the artificial cerebros...

journal_title：Stroke

authors： Rosenblum WI,Segreti AC

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelins (ETs) are potent vasoconstrictors and may play a role in the pathophysiology of several diseases. Limited and controversial data exist on their role in human ischemic stroke. We planned a prospective, observational, and longitudinal clinical study to test whether ET-1 levels increase ...

journal_title：Stroke

authors： Haapaniemi E,Tatlisumak T,Hamel K,Soinne L,Lanni C,Opgenorth TJ,Kaste M

更新日期：2000-03-01 00:00:00

abstract：:The external diameters of rat and rabbit basilar arteries were determined before and after formaldehyde fixation in relaxed and drug constricted vessels. Fixation usually resulted in an immediate vessel constriction followed by partial relaxation after several hours. However, the results were inconstant from vessel to...

journal_title：Stroke

authors： Hart MN,O'Donnell SL

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Using the dexamethasone suppression test, we studied the suppressibility of the cortisol axis and its clinical determinants at various time points after stroke. A major aim was to examine the dexamethasone test as a diagnostic tool for the diagnosis of major depression in stroke patients. METHOD...

journal_title：Stroke

authors： Aström M,Olsson T,Asplund K

更新日期：1993-01-01 00:00:00

abstract：:An anecdotal series of nine patients (three men and six women with an average age of 57 years) presented with progressive neurologic deterioration while on medical therapy for large right hemispheric cerebral infarction. Clinical signs of uncal herniation (anisocoria or fixed and dilated pupils, and/or left hemiplegia...

journal_title：Stroke

authors： Delashaw JB,Broaddus WC,Kassell NF,Haley EC,Pendleton GA,Vollmer DG,Maggio WW,Grady MS

更新日期：1990-06-01 00:00:00