Are hypertension or cardiac embolism likely causes of lacunar infarction?

abstract：BACKGROUND AND PURPOSE:We have shown that acute treatment with candesartan in an experimental model of stroke resulted in vascular protection and improved outcomes at 24 hours poststroke, but the mechanisms are unknown. We now examine effects of candesartan on proangiogenic factors and 7-day outcomes using the same tre...

journal_title：Stroke

authors： Kozak A,Ergul A,El-Remessy AB,Johnson MH,Machado LS,Elewa HF,Abdelsaid M,Wiley DC,Fagan SC

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of flow diverter (FD) on hemodynamic changes observed in aneurysms is inevitably affected by the actual structural configuration of deployed FD. We studied the resultant hemodynamic changes after implantation of FDs using computational fluid dynamic simulations based on micro-computed ...

journal_title：Stroke

authors： Huang Q,Xu J,Cheng J,Wang S,Wang K,Liu JM

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microwave Radiometry (MWR) allows in vivo noninvasive assessment of internal temperature of tissues. The aim of the present study was to evaluate in patients with ischemic stroke and bilateral carotid plaques (1) whether ipsilateral carotid arteries exhibit higher temperature differences (ΔT), as...

journal_title：Stroke

authors： Toutouzas K,Benetos G,Drakopoulou M,Deligianni C,Spengos K,Stefanadis C,Siores E,Tousoulis D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Copeptin has been associated with recurrent cerebrovascular events after transient ischemic attack (TIA). In an independent cohort, we evaluated copeptin for the prediction of recurrent cerebrovascular events within 3 months after TIA and assessed the incremental value of copeptin compared with t...

journal_title：Stroke

authors： De Marchis GM,Weck A,Audebert H,Benik S,Foerch C,Buhl D,Schuetz P,Jung S,Seiler M,Morgenthaler NG,Mattle HP,Mueller B,Christ-Crain M,Arnold M,Katan M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess the geographic proximity of patients with stroke in California to centers that performed specific threshold volumes of mechanical embolectomy procedures each year. METHODS:We identified all patients who were hospitalized for acute ischemic stroke at all nonfederal acute care ...

journal_title：Stroke

authors： Choi JC,Hsia RY,Kim AS

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In a previous study from our laboratory, ritanserin, a specific 5-HT2 serotonin receptor antagonist, reduced ischemic damage in the setting of transient global ischemia. In this study, we examined the effect of ritanserin on ischemic cerebral blood flow, systemic blood pressure, and infarct volum...

journal_title：Stroke

authors： Takagi K,Ginsberg MD,Globus MY,Busto R,Dietrich WD

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We know that significant cardiac involvement can occur in patients with acute intracranial hemorrhage, particularly in those with subarachnoid hemorrhage. These patients may present with electrocardiographic abnormalities that were previously thought to be benign. However, many die of cardiovascu...

journal_title：Stroke

authors： Elrifai AM,Bailes JE,Shih SR,Dianzumba S,Brillman J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Poststroke cognitive impairment is frequent. There are, however, few longitudinal studies examining delayed changes in poststroke cognition. METHODS:As part of a longitudinal study of incident dementia after stroke, 115 older stroke survivors (>75 years of age) without dementia were evaluated at...

journal_title：Stroke

authors： Ballard C,Rowan E,Stephens S,Kalaria R,Kenny RA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identifying occult coronary artery stenosis may improve secondary prevention of stroke patients. The aim of this study was to derive and validate a simple score to predict severe occult coronary artery stenosis in stroke patients. METHODS:We derived a score from a French hospital-based cohort of...

journal_title：Stroke

authors： Calvet D,Song D,Yoo J,Turc G,Sablayrolles JL,Choi BW,Heo JH,Mas JL

更新日期：2014-01-01 00:00:00

abstract：:Recent success with thrombolytic therapy for acute myocardial infarction has stimulated interest in its use for stroke. To determine the hemorrhagic potential of thrombolytic therapy in experimental cerebral infarction, we compared a group of tissue plasminogen activator-treated rabbits (n = 4) with 2 groups of strept...

journal_title：Stroke

authors： Slivka A,Pulsinelli W

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelial progenitor cells (EPCs) migrate from bone marrow to systemic circulation in response to tissue ischemia where they differentiate into mature endothelial cells for angiogenesis in situ. This study tested the hypothesis that the level of circulating EPCs is substantially increased and p...

journal_title：Stroke

authors： Yip HK,Chang LT,Chang WN,Lu CH,Liou CW,Lan MY,Liu JS,Youssef AA,Chang HW

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Discharge ICD-9-CM (International Classification of Diseases, 9th Revision, Clinical Modification) codes have been used to identify patients with acute stroke for epidemiological, quality of care, and cost studies. The aim of this study was to determine if the accuracy of the primary ICD-9-CM cod...

journal_title：Stroke

authors： Goldstein LB

更新日期：1998-08-01 00:00:00

abstract：:We observed the effects of a new thyrotropin-releasing hormone derivative, YM-14673 (N alpha-[[(S)-4-oxo-2-azetidinyl]carbonyl]-L-histidyl-L-prolinamide dihydrate), on behavioral changes in rats for 3 weeks after focal cerebral ischemia. Under halothane anesthesia, the left middle cerebral artery was occluded via a tr...

journal_title：Stroke

authors： Yamamoto M,Tamura A,Kirino T,Shimizu M,Sano K

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have investigated the pathophysiological mechanisms of dysphagia in Wallenberg's syndrome (WS) that are due to lateral medullary infarction (LMI). METHODS:Twenty patients with WS were evaluated by means of clinical and electrophysiological methods that measured the oropharyngeal phase of volu...

journal_title：Stroke

authors： Aydogdu I,Ertekin C,Tarlaci S,Turman B,Kiylioglu N,Secil Y

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately one fourth of stroke occur during sleep. Despite the clinical and radiological similarities between wake-up stroke (WUS) and non-WUS, the functional outcomes of WUS are largely unknown. METHODS:This retrospective analysis reviewed 2289 consecutive patients with acute ischemic strok...

journal_title：Stroke

authors： Kim BJ,Lee SH,Shin CW,Ryu WS,Kim CK,Yoon BW

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Risk-factor modeling has been proposed to identify patients with carotid stenosis who will most benefit from surgery. Validation by independent institutions performing carotid endarterectomy is necessary to determine the applicability of such models to the individual patient. METHODS:A series of...

journal_title：Stroke

authors： Barth A,Bassetti C

更新日期：2003-02-01 00:00:00

abstract：:Background and Purpose- The GLX (glycocalyx) is a protein/polysaccharide meshwork at the cellular surface. Consisting largely of glycosaminoglycans and proteoglycans, the GLX can shed in response to stress. In this study, we assay 11 components of the GLX in plasma from patients with ischemic stroke from a longitudina...

journal_title：Stroke

authors： DellaValle B,Hasseldam H,Johansen FF,Iversen HK,Rungby J,Hempel C

更新日期：2019-10-01 00:00:00

abstract：:Background and Purpose- Several vascular risk factors are known to be associated with the occurrence of intracranial aneurysms (IAs). Coronary artery calcium (CAC), which reflects the atherosclerotic burden of the coronary arteries, is a known predictor of cardiovascular events and stroke. We investigated the relation...

journal_title：Stroke

authors： Cho BH,Kim JH,Suh SH,Baik SJ,Lee HS,Kim J,Lee KY

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data are scarce on both stroke incidence rates and outcomes in Greece and in rural areas in particular. We performed a prospective population-based study evaluating the incidence of first-ever stroke in the Evros prefecture, a region of a total 147 947 residents located in North Eastern Greece. ...

journal_title：Stroke

authors： Tsivgoulis G,Patousi A,Pikilidou M,Birbilis T,Katsanos AH,Mantatzis M,Asimis A,Papanas N,Skendros P,Terzoudi A,Karamanli A,Kouroumichakis I,Zebekakis P,Maltezos E,Piperidou C,Vadikolias K,Heliopoulos I

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cardiovascular and pulmonary factors contributing to impaired peak oxygen uptake (VO2) in patients with stroke (SP) are not well known. We assessed cardiovascular function, pulmonary gas exchange, and ventilation in SP and healthy age, gender, and activity-matched control subjects. METHODS:Ten h...

journal_title：Stroke

authors： Tomczak CR,Jelani A,Haennel RG,Haykowsky MJ,Welsh R,Manns PJ

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aneurysmal subarachnoid hemorrhage (SAH) is a cerebrovascular disease with a high mortality rate and severe disability. Longitudinal studies investigating health-economic costs in SAH are scare and only one of them analyzed cost-driving factors. The objective was to evaluate first-year costs in G...

journal_title：Stroke

authors： Dodel R,Winter Y,Ringel F,Spottke A,Gharevi N,Müller I,Klockgether T,Schramm J,Urbach H,Meyer B

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Telomerase reverse transcriptase (TERT) is tightly related to the resistance of cells to stress and injury. However, little is known about the roles of TERT in the nervous system. We try to investigate the effects of TERT on the function of astrocytes in developing rat brains subjected to hypoxia...

journal_title：Stroke

authors： Qu Y,Duan Z,Zhao F,Wei D,Zhang J,Tang B,Li J,Yang C,Mu D

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The use of bare metal stents to treat symptomatic intracranial stenosis may be associated with significant restenosis rates. The advent of drug-eluting stents (DESs) in the coronary circulation has resulted in a reduction of restenosis rates. We report our technical success rate and short-term re...

journal_title：Stroke

authors： Gupta R,Al-Ali F,Thomas AJ,Horowitz MB,Barrow T,Vora NA,Uchino K,Hammer MD,Wechsler LR,Jovin TG

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lacunar ischemic stroke accounts for 25% of all ischemic strokes, but the exact etiology is unknown. Numerous pathophysiologies have been proposed, including atheroma and endothelial dysfunction. Models of any of these pathological features would aid understanding of the etiology and help develop...

journal_title：Stroke

authors： Bailey EL,McCulloch J,Sudlow C,Wardlaw JM

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Controlled multicenter studies have demonstrated the efficacy of systemic recombinant tissue-type plasminogen activator (rtPA) treatment in selected cases of acute ischemic stroke. The feasibility of this therapeutic option in clinical practice was assessed in a community-based approach. METHODS...

journal_title：Stroke

authors： Grond M,Stenzel C,Schmülling S,Rudolf J,Neveling M,Lechleuthner A,Schneweis S,Heiss WD

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelins (ETs) are potent vasoconstrictors and may play a role in the pathophysiology of several diseases. Limited and controversial data exist on their role in human ischemic stroke. We planned a prospective, observational, and longitudinal clinical study to test whether ET-1 levels increase ...

journal_title：Stroke

authors： Haapaniemi E,Tatlisumak T,Hamel K,Soinne L,Lanni C,Opgenorth TJ,Kaste M

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stent placement has been applied in small case series as a rescue therapy in combination with different thrombolytic agents, percutaneous balloon angioplasty (PTA), and mechanical thromboembolectomy (MT) in acute stroke treatment. These studies report a considerable mortality and a high rate of i...

journal_title：Stroke

authors： Brekenfeld C,Schroth G,Mattle HP,Do DD,Remonda L,Mordasini P,Arnold M,Nedeltchev K,Meier N,Gralla J

更新日期：2009-03-01 00:00:00

abstract：:Background and Purpose- Intracranial thrombi can be characterized according to their permeability as measured by contrast agent penetration. Thrombus composition and its associated pathogenesis are important factors affecting treatment and secondary prevention. We aimed to explore the histopathologic factors explainin...

journal_title：Stroke

authors： Berndt M,Friedrich B,Maegerlein C,Moench S,Hedderich D,Lehm M,Zimmer C,Straeter A,Poppert H,Wunderlich S,Schirmer L,Oberdieck P,Kaesmacher J,Boeckh-Behrens T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) growth predicts mortality and functional outcome. We hypothesized that irregular hematoma shape and density heterogeneity, reflecting active, multifocal bleeding or a variable bleeding time course, would predict ICH growth. METHODS:Three raters examined baseline su...

journal_title：Stroke

authors： Barras CD,Tress BM,Christensen S,MacGregor L,Collins M,Desmond PM,Skolnick BE,Mayer SA,Broderick JP,Diringer MN,Steiner T,Davis SM,Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators.

更新日期：2009-04-01 00:00:00

abstract：:Background and Purpose- Information on what effect disability before stroke can have on stroke outcome is lacking. We assessed prestroke disability in relation to poststroke hospital outcome. Methods- Analysis of prospectively collected data from the Sentinel Stroke National Audit Programme. A total of 1656 men (mean ...

journal_title：Stroke

authors： Han TS,Fry CH,Gulli G,Affley B,Robin J,Irvin-Sellers M,Fluck D,Kakar P,Sharma S,Sharma P

更新日期：2020-02-01 00:00:00