Regional cerebral blood flow in the anesthetized mouse as measured by local hydrogen clearance.

abstract：:Nontraumatic intracerebral hemorrhage (ICH) remains a devastating condition with 30-day mortality rates of 35% to 52%. Until the pathophysiology of this condition is better understood, it will not be possible to develop effective therapies. Studies of cerebral blood flow and metabolism in patients with acute ICH show ...

journal_title：Stroke

authors： Powers WJ

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pneumonia has been estimated to occur in about one third of patients after acute stroke. Only limited data are available on stroke-associated pneumonia (SAP) in specialized neurological intensive care units (NICUs). METHODS:We enrolled 124 patients with acute stroke who were treated at our unive...

journal_title：Stroke

authors： Hilker R,Poetter C,Findeisen N,Sobesky J,Jacobs A,Neveling M,Heiss WD

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perivascularly positioned cerebral mast cells (MC) have been shown to participate in acute blood-brain barrier disruption and expansive brain edema following experimental transient cerebral ischemia. However, the underlying molecular mechanisms remain unknown. Because proteolytic gelatinase enzym...

journal_title：Stroke

authors： Mattila OS,Strbian D,Saksi J,Pikkarainen TO,Rantanen V,Tatlisumak T,Lindsberg PJ

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Warfarin reduces stroke risk in studies of predominantly white patients with atrial fibrillation (AF). Whether nonwhites also have lower rates of stroke while treated with warfarin is unclear. METHODS:A multiethnic stroke-free cohort hospitalized with nonrheumatic AF was identified in a large he...

journal_title：Stroke

authors： Shen AY,Yao JF,Brar SS,Jorgensen MB,Wang X,Chen W

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke incidence and mortality are declining rapidly in developed countries. Little data on ethnic-specific stroke recurrence trends exist. Fourteen-year stroke recurrence trend estimates were evaluated in Mexican Americans and non-Hispanic whites in a population-based study. METHODS:Recurrent s...

journal_title：Stroke

authors： Sozener CB,Lisabeth LD,Shafie-Khorassani F,Kim S,Zahuranec DB,Brown DL,Skolarus LE,Burke JF,Kerber KA,Meurer WJ,Case E,Morgenstern LB

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Current guidelines recommend against routine auscultation of carotid arteries, believing that carotid bruits are poor predictors of either underlying carotid stenosis or stroke risk in asymptomatic patients. We investigated whether the presence of a carotid bruit is associated with increased risk...

journal_title：Stroke

authors： Pickett CA,Jackson JL,Hemann BA,Atwood JE

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To elucidate how the motor pathways rewire the denervated tissue after stroke, we investigated remodeling of the corticospinal tract (CST) in transgenic mice with yellow fluorescent protein CST labeling in conjunction with transsynaptic pseudorabies virus retrograde tracing. METHODS:Adult male C...

journal_title：Stroke

authors： Liu Z,Zhang RL,Li Y,Cui Y,Chopp M

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The newly-described computed tomography angiography (CTA) Spot Sign is present in about one third of patients with acute primary intracerebral hemorrhage (PICH) and predicts hematoma expansion. This sign has not been systematically evaluated in patients with secondary causes of ICH, and mimics ha...

journal_title：Stroke

authors： Gazzola S,Aviv RI,Gladstone DJ,Mallia G,Li V,Fox AJ,Symons SP

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Enlarged perivascular spaces in the brain are common but generally overlooked and of uncertain pathophysiology. They may reflect underlying cerebral small vessel disease. We determined whether enlarged perivascular spaces were associated with lacunar stroke subtype and white matter hyperintensiti...

journal_title：Stroke

authors： Doubal FN,MacLullich AM,Ferguson KJ,Dennis MS,Wardlaw JM

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Higher proportions of hemorrhagic stroke and lacunar infarction were reported in rural Japan compared with those in Western countries. We examined the relative proportions of stroke subtypes in an urban Japanese city where westernized lifestyles are more common than in rural areas. METHODS:Strok...

journal_title：Stroke

authors： Kitamura A,Nakagawa Y,Sato M,Iso H,Sato S,Imano H,Kiyama M,Okada T,Okada H,Iida M,Shimamoto T

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Current guidelines suggest that cardiac arrest (CA) survivors should be ventilated with 100% O(2) after resuscitation. Breathing 100% O(2) may worsen neurological outcome after experimental CA. This study tested the hypothesis that graded reoxygenation, with oximetry guidance, can safely reduce F...

journal_title：Stroke

authors： Balan IS,Fiskum G,Hazelton J,Cotto-Cumba C,Rosenthal RE

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The CHA2DS2-VASc stroke score (congestive heart failure, hypertension, age ≥75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65-74, female) is used in most guidelines for risk stratification in atrial fibrillation (AF), but most data for ...

journal_title：Stroke

authors： Kim TH,Yang PS,Uhm JS,Kim JY,Pak HN,Lee MH,Joung B,Lip GYH

更新日期：2017-06-01 00:00:00

abstract：:Brief episodes of ischemia can protect against subsequent damaging ischemic events; however, the molecular mechanisms responsible for protection are poorly understood. Identifying genes involved in this process could provide insight into cell survival and treatment of stroke. We developed a murine model of ischemic pr...

journal_title：Stroke

authors： Stenzel-Poore MP,Stevens SL,Simon RP

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to measure the overall rate of usage of tissue-type plasminogen activator (tPA) for ischemic stroke at academic medical centers, and to determine whether ethnicity was associated with usage. METHODS:Between June and December 1999, 42 academic medical centers in the United States each i...

journal_title：Stroke

authors： Johnston SC,Fung LH,Gillum LA,Smith WS,Brass LM,Lichtman JH,Brown AN

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Endovascular treatment of intracranial aneurysms is safe and effective but too often is followed by recurrences. Gene therapy may improve healing after embolization, and endovascular approaches may offer future in situ delivery systems designed to prevent aneurysm rupture. SUMMARY OF REVIEW:Advances in coil...

journal_title：Stroke

authors： Ribourtout E,Raymond J

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few studies are available that have addressed the prevalence of early-onset dementia (EOD), including early-onset Alzheimer disease and other forms of dementia in Japan. METHODS:A 2-step postal survey was sent to all of the 2475 institutions providing medical or care services for individuals wit...

journal_title：Stroke

authors： Ikejima C,Yasuno F,Mizukami K,Sasaki M,Tanimukai S,Asada T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke community surveillance projects often focus on hospital data rates. We hypothesized that not including strokes which occurred in nursing homes or at home would differentially affect race/ethnic stroke rates. METHODS:Texas vital statistics data were studied to compare age-specific (45 to 5...

journal_title：Stroke

authors： Wein TH,Smith MA,Morgenstern LB

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The extent of cardiac investigation required in patients with coexistent symptomatic carotid and cardiac disease is unsettled. This study compared the outlook for patients symptomatic from carotid stenosis with and without a history of symptomatic ischemic heart disease (IHD). METHODS:The risk o...

journal_title：Stroke

authors： Gates PC,Eliasziw M,Algra A,Barnett HJ,Gunton RW,North American Symptomatic Carotid Endarterectomy Trial Group.

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Impaired rheological properties of as well as cytotoxic substances produced by granulocytes may contribute to tissue damage in acute ischemic stroke. To assess changes in the properties of circulating granulocytes, we measured their adhesion, deformability, and superoxide generation in the first ...

journal_title：Stroke

authors： Grau AJ,Berger E,Sung KL,Schmid-Schönbein GW

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fruits and vegetables are known for their beneficial effects on chronic diseases. The purpose of the present study was to investigate the protective effect of a diet rich in fruits and vegetables on total stroke mortality and its 2 main subtypes in men and women separately. METHODS:A prospective...

journal_title：Stroke

authors： Sauvaget C,Nagano J,Allen N,Kodama K

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:After stroke, individuals have decreased mobility of the hemiparetic leg, which demands less muscle oxygen consumption; thus, blood flow decreases. The purpose of this study was to determine the effect of single limb exercise (SLE) on femoral artery blood flow, diameter, and peak flow velocity in...

journal_title：Stroke

authors： Billinger SA,Gajewski BJ,Guo LX,Kluding PM

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We performed the present study to determine whether the site of occlusion in the vertebrobasilar circulation could be identified by the measurement of blood flow velocity in the bilateral vertebral arteries. METHODS:Using color-coded duplex carotid ultrasonography, we measured the time-averaged ...

journal_title：Stroke

authors： Kimura K,Yasaka M,Moriyasu H,Tsuchiya T,Yamaguchi T

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Whether and how the arterial pathology underlying lacunar ischemic stroke differs from the atherothrombotic processes causing most other ischemic strokes is still debated. Different risks of recurrent stroke and MI after lacunar versus nonlacunar ischemic stroke may support a distinct lacunar art...

journal_title：Stroke

authors： Jackson CA,Hutchison A,Dennis MS,Wardlaw JM,Lewis SC,Sudlow CL

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is not known what fraction of patients with symptomatic cerebral aneurysms are misdiagnosed at initial medical presentation. It is also not clear whether misdiagnosed patients more frequently deteriorate before definitive aneurysm diagnosis and therapy or achieve a poorer outcome than correctl...

journal_title：Stroke

authors： Mayer PL,Awad IA,Todor R,Harbaugh K,Varnavas G,Lansen TA,Dickey P,Harbaugh R,Hopkins LN

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Severe cerebral edema is associated with poor outcome in patients with acute stroke. Experimental studies suggest that astrocytic endothelin-1 (ET-1) has deleterious effects on water homeostasis, cerebral edema, and blood brain barrier (BBB) integrity, which contribute to more severe ischemic bra...

journal_title：Stroke

authors： Moldes O,Sobrino T,Millán M,Castellanos M,Pérez de la Ossa N,Leira R,Serena J,Vivancos J,Dávalos A,Castillo J

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Three-dimensional MRI segmentation may be useful to better understand the physiopathology of lacunar infarctions. Using this technique, the distribution of lacunar infarctions volumes has been recently reported in patients with cerebral autosomal-dominant arteriopathy with subcortical infarcts an...

journal_title：Stroke

authors： Hervé D,Godin O,Dufouil C,Viswanathan A,Jouvent E,Pachaï C,Guichard JP,Bousser MG,Dichgans M,Chabriat H

更新日期：2009-01-01 00:00:00

abstract：:A 34-year-old, single Japanese woman with active Takayasu's disease presented with stenosed bilateral common carotid arteries, subtotal occlusion of the left subclavian artery, and complete occlusion of the ipsilateral proximal vertebral artery, as demonstrated by angiography. A right subclavian-left vertebral bypass ...

journal_title：Stroke

authors： Ishikawa K,Yonekawa Y

更新日期：1987-05-01 00:00:00

abstract：:Adenylate cyclase activity was investigated in either homogenate or particulate fractions from the frontal cerebral cortex of the gerbil following five experimental conditions of bilateral ischemia. After periods of 15 min ischemia, 15 min ischemia plus 15 min of recirculation or 60 min ischemia the enzyme generally d...

journal_title：Stroke

authors： Taylor MD,Palmer GC,Callahan AS 3rd

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Time elapsed from last-known well (LKW) and baseline imaging results are influential on endovascular thrombectomy (EVT) outcomes. METHODS:In a prospective multicenter cohort study of imaging selection for endovascular thrombectomy (SELECT [Optimizing Patient's Selection for Endovascular Treatmen...

journal_title：Stroke

authors： Sarraj A,Hassan AE,Grotta J,Blackburn S,Day A,Abraham M,Sitton C,Dannenbaum M,Cai C,Pujara D,Hicks W,Vora N,Budzik R,Shaker F,Arora A,Riascos RF,Kamal H,Martin-Schild S,Lansberg M,Gupta R,Albers GW,SELECT Invest

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There are uncertainties surrounding the optimal management of patients with brain swelling after an ischemic stroke. Guidelines are needed on how to manage this major complication, how to provide the best comprehensive neurological and medical care, and how to best inform families facing complex ...

journal_title：Stroke

authors： Wijdicks EF,Sheth KN,Carter BS,Greer DM,Kasner SE,Kimberly WT,Schwab S,Smith EE,Tamargo RJ,Wintermark M,American Heart Association Stroke Council.

更新日期：2014-04-01 00:00:00