Three-dimensional MRI analysis of individual volume of Lacunes in CADASIL.

abstract：BACKGROUND:In 15% to 20% of patients with a spontaneous subarachnoid hemorrhage, no aneurysm is found on the first angiogram. This review emphasizes that this group of patients is in fact heterogeneous and describes the clinical features, pattern of hemorrhage on early computed tomographic (CT) scan, prognosis, and pro...

journal_title：Stroke

authors： Rinkel GJ,van Gijn J,Wijdicks EF

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to demonstrate the contribution of axonal remodeling of the corticospinal tract (CST) in the spinal cord to functional outcome after stroke. METHODS:Bilateral pyramidotomy (BPT) or sham-BPT was performed in mice with transgenic yellow fluorescent protein labeling in the CST subjected t...

journal_title：Stroke

authors： Liu Z,Chopp M,Ding X,Cui Y,Li Y

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of the study is to compare the reliability of the Barthel activities of daily living score, which assesses disability, with the Rankin scale, which assesses handicap, and to determine their mutual agreement. METHODS:Fifty patients with stroke of varying severity were identified by a ...

journal_title：Stroke

authors： Wolfe CD,Taub NA,Woodrow EJ,Burney PG

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Citicoline, a naturally occurring precursor of phosphatidylcholine, is neuroprotective and is currently being assessed in clinical trials. To evaluate potential synergistic neuroprotective effects of prolonged citicoline treatment and early N-methyl-D-aspartate (NMDA) antagonist therapy, suboptim...

journal_title：Stroke

authors： Onal MZ,Li F,Tatlisumak T,Locke KW,Sandage BW Jr,Fisher M

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Admission infarct core lesion size is an important determinant of management and outcome in acute (<9 hours) stroke. Our purposes were to: (1) determine the optimal CT perfusion parameter to define infarct core using various postprocessing platforms; and (2) establish the degree of variability in...

journal_title：Stroke

authors： Kamalian S,Kamalian S,Maas MB,Goldmacher GV,Payabvash S,Akbar A,Schaefer PW,Furie KL,Gonzalez RG,Lev MH

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recanalization status after intravenous thrombolysis (IVT) in patients with ischemic stroke is a reference point to proceed with a rescue reperfusion intervention, although early neurological improvement (NI) may preclude endovascular procedures. We aimed to evaluate the importance of restoration...

journal_title：Stroke

authors： Kharitonova TV,Melo TP,Andersen G,Egido JA,Castillo J,Wahlgren N,SITS investigators.

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The mechanisms underlying smooth muscle relaxations of cerebral arteries in response to nitric oxide (NO) and cyclic GMP (cGMP) are still not completely understood. The present study was designed to determine the role of potassium channels in the relaxations to NO donors 3-morpholinosydnonimine (...

journal_title：Stroke

authors： Onoue H,Katusic ZS

更新日期：1997-06-01 00:00:00

abstract：:The effect of very-low-dose aspirin as an antithrombotic agent was evaluated blindly in 301 patients who had recently undergone carotid endarterectomy. After randomization, 150 patients received aspirin and 151 received placebo. The two groups were comparable with regard to age, sex, blood pressure, previous cerebrova...

journal_title：Stroke

authors： Boysen G,Sørensen PS,Juhler M,Andersen AR,Boas J,Olsen JS,Joensen P

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Improved neurological outcome with postarrest hypertensive hemodilution in an earlier study could be the result of more homogeneous cerebral perfusion and improved O2 delivery. We explored global, regional, and local cerebral blood flow by stable xenon-enhanced computed tomography and global cerebral metabol...

journal_title：Stroke

authors： Leonov Y,Sterz F,Safar P,Johnson DW,Tisherman SA,Oku K

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional stimulation is accompanied by increases in regional cerebral blood flow which exceed metabolic demands under normal circumstances, but it is unknown whether functional stimulation is beneficial or detrimental in the setting of acute ischemia. The aim of this study was to determine the ...

journal_title：Stroke

authors： Burnett MG,Shimazu T,Szabados T,Muramatsu H,Detre JA,Greenberg JH

更新日期：2006-05-01 00:00:00

abstract：:The effects of halothane on intracellular membrane potential (Em) and force development in cat MCA were studied. Halothane (0.07-0.14 mM/1) relaxed isolated MCA which had developed myogenic tone. Measurement of Em showed that halothane depolarized this preparation in a dose-dependent fashion in the face of vessel rela...

journal_title：Stroke

authors： Harder DR,Gradall K,Madden JA,Kampine JP

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Results from large multicenter studies have shown that carotid endarterectomy, performed with low perioperative morbidity and mortality, is beneficial for patients with symptomatic carotid stenosis > or = 70% as calculated according to strict angiographic criteria. To apply these results in clini...

journal_title：Stroke

authors： Chang YJ,Golby AJ,Albers GW

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Animal studies of cerebral arteries 2 to 3 days after experimental subarachnoid hemorrhage (SAH) provide evidence of arterial change such as hyperresponsiveness to contractile agonists. There is evidence that small arteries, as well as those large enough to be seen on angiography, may be involved...

journal_title：Stroke

authors： Bevan JA,Bevan RD,Walters CL,Wellman T

更新日期：1998-12-01 00:00:00

abstract：:An anecdotal series of nine patients (three men and six women with an average age of 57 years) presented with progressive neurologic deterioration while on medical therapy for large right hemispheric cerebral infarction. Clinical signs of uncal herniation (anisocoria or fixed and dilated pupils, and/or left hemiplegia...

journal_title：Stroke

authors： Delashaw JB,Broaddus WC,Kassell NF,Haley EC,Pendleton GA,Vollmer DG,Maggio WW,Grady MS

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The relationship between diabetic retinopathy and ischemic stroke is uncertain and examined in this study. METHODS:A population-based, prospective cohort study of 1617 middle-aged persons with diabetes. Diabetic retinopathy signs were ascertained from retinal photographs, and incident ischemic s...

journal_title：Stroke

authors： Cheung N,Rogers S,Couper DJ,Klein R,Sharrett AR,Wong TY

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pathogenesis of periventricular hyperintensity (PVH) is still uncertain. We investigated the relationship between PVH and risk factors for cerebrovascular diseases, especially extracranial carotid artery stenosis (ECAS). METHODS:We studied PVH and ECAS in 323 subjects between 1991 and 1994. ...

journal_title：Stroke

authors： Adachi T,Takagi M,Hoshino H,Inafuku T

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic injury triggers multiple pathological responses in the brain tissue, including spreading depolarizations across the cerebral cortex (cortical spreading depolarizations [CSD]). Microglia have been recently shown to play a significant role in the propagation of CSD. However, the intracellu...

journal_title：Stroke

authors： Liu L,Kearns KN,Eli I,Sharifi KA,Soldozy S,Carlson EW,Scott KW,Sluzewski MF,Acton ST,Stauderman KA,Kalani MYS,Park M,Tvrdik P

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Outcome after mechanical thrombectomy for ischemic stroke may be influenced by blood pressure (BP). This study aims to assess the association of BP changes during general anesthesia versus conscious sedation with functional outcome after mechanical thrombectomy. METHODS:SIESTA (Sedation vs Intub...

journal_title：Stroke

authors： Schönenberger S,Uhlmann L,Ungerer M,Pfaff J,Nagel S,Klose C,Bendszus M,Wick W,Ringleb PA,Kieser M,Möhlenbruch MA,Bösel J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is an inverse association between dairy food consumption and the incidence of stroke in observational studies. However, it is unknown whether the relationship is causal or, if so, what components in milk are responsible for reducing the incidence of stroke. METHODS:Stroke-prone spontaneous...

journal_title：Stroke

authors： Chiba T,Itoh T,Tabuchi M,Ooshima K,Satou T,Ezaki O

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We tested the hypothesis that circulating microRNAs (miRNAs) present in plasma might display a specific signature in patients with intracerebral hemorrhage. METHODS:Global miRNA profiles were determined with the Agilent Human miRNA Microarray platform, and validated by quantitative polymerase ch...

journal_title：Stroke

authors： Guo D,Liu J,Wang W,Hao F,Sun X,Wu X,Bu P,Zhang Y,Liu Y,Liu F,Zhang Q,Jiang F

更新日期：2013-06-01 00:00:00

abstract：:A new technique is described for the autoradiographic determination of regional brain glucose metabolism employing 14C labeled glucose as substrate and measurement principles previously described for whole brain. Regional glucose values correlate closely with those reported for the 14C-deoxyglucose technique. The meth...

journal_title：Stroke

authors： Hawkins R,Hass WK,Ransohoff J

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:MRI characterization of carotid plaque has been studied recently as a potential tool to predict stroke caused by carotid atherosclerosis. We performed a systematic review and meta-analysis to summarize the association of MRI-determined intraplaque hemorrhage, lipid-rich necrotic core, and thinnin...

journal_title：Stroke

authors： Gupta A,Baradaran H,Schweitzer AD,Kamel H,Pandya A,Delgado D,Dunning A,Mushlin AI,Sanelli PC

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animal models of cerebral ischemia, matrix metalloproteinase (MMP) expression was significantly increased and related to blood-brain barrier disruption, edema formation, and hemorrhagic transformation (HT). MMP inhibitors reduce HT after embolic ischemia in tissue-type plasminogen activator-tr...

journal_title：Stroke

authors： Montaner J,Alvarez-Sabín J,Molina CA,Anglés A,Abilleira S,Arenillas J,Monasterio J

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The newly-described computed tomography angiography (CTA) Spot Sign is present in about one third of patients with acute primary intracerebral hemorrhage (PICH) and predicts hematoma expansion. This sign has not been systematically evaluated in patients with secondary causes of ICH, and mimics ha...

journal_title：Stroke

authors： Gazzola S,Aviv RI,Gladstone DJ,Mallia G,Li V,Fox AJ,Symons SP

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) lower serum cholesterol and decrease the incidence of stroke and cardiovascular disease. There is growing evidence that statins exert some of their beneficial effects independent of cholesterol lowering. Indeed, we...

journal_title：Stroke

authors： Amin-Hanjani S,Stagliano NE,Yamada M,Huang PL,Liao JK,Moskowitz MA

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The applicability of a novel differentiation technique in embolus detection based on the coincidence principle and using a multigate probe was evaluated in this study. METHODS:According to the coincidence method, high-intensity transients should only be classified as microembolic signals if they...

journal_title：Stroke

authors： Georgiadis D,Goeke J,Hill M,König M,Nabavi DG,Stögbauer F,Zunker P,Ringelstein EB

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The current report details our initial periprocedural experience with Wingspan (Boston Scientific/Target), the first self-expanding stent system designed for the treatment of intracranial atheromatous disease. METHODS:All patients undergoing angioplasty and stenting with the Gateway balloon-Wing...

journal_title：Stroke

authors： Fiorella D,Levy EI,Turk AS,Albuquerque FC,Niemann DB,Aagaard-Kienitz B,Hanel RA,Woo H,Rasmussen PA,Hopkins LN,Masaryk TJ,McDougall CG

更新日期：2007-03-01 00:00:00

abstract：:Background and Purpose- Persistent depression after ischemic stroke is common in stroke survivors and may be even higher in family caregivers, but few studies have examined depressive symptom levels and their predictors in patient and caregiver groups simultaneously. Methods- Stroke survivors and their family caregive...

journal_title：Stroke

authors： Roth DL,Haley WE,Sheehan OC,Liu C,Clay OJ,Rhodes JD,Judd SE,Dhamoon M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Poststroke cognitive impairment is frequent. There are, however, few longitudinal studies examining delayed changes in poststroke cognition. METHODS:As part of a longitudinal study of incident dementia after stroke, 115 older stroke survivors (>75 years of age) without dementia were evaluated at...

journal_title：Stroke

authors： Ballard C,Rowan E,Stephens S,Kalaria R,Kenny RA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelin receptor antagonists such as clazosentan decrease large-artery vasospasm after experimental and clinical subarachnoid hemorrhage. We used clazosentan to gain insight into the pathophysiology of subarachnoid hemorrhage by determining if decreasing vasospasm is associated with alleviatio...

journal_title：Stroke

authors： Sabri M,Ai J,Macdonald RL

更新日期：2011-05-01 00:00:00