Oximetry-guided reoxygenation improves neurological outcome after experimental cardiac arrest.

abstract：BACKGROUND AND PURPOSE:Vertebrobasilar territory ischemia (VBI) leads to disabling neurological symptoms and poses a risk for stroke by an embolic or flow-related mechanism. We present our clinical experience in the endovascular treatment of patients with symptomatic VBI from severe atherosclerosis or dissection of the...

journal_title：Stroke

authors： Malek AM,Higashida RT,Phatouros CC,Lempert TE,Meyers PM,Gress DR,Dowd CF,Halbach VV

更新日期：1999-10-01 00:00:00

abstract：:The trends in age adjusted and age and sex specific mortality rates for the period 1968-1980 are compared for ischaemic heart disease and cerebrovascular disease. For both sexes and at all ages over 45 the mortality rates for cerebrovascular disease have fallen significantly. However, the mortality rates for ischaemic...

journal_title：Stroke

authors： Haberman S,Capildeo R,Rose FC

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although insulin resistance and hyperinsulinemia play a crucial role in the pathogenesis of atherosclerosis, little is known about their roles in ischemic stroke. The purpose of this study was to clarify whether insulin resistance and hyperinsulinemia are causative factors in the pathogenesis of ...

journal_title：Stroke

authors： Shinozaki K,Naritomi H,Shimizu T,Suzuki M,Ikebuchi M,Sawada T,Harano Y

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Standard radiographic criteria for hematoma enlargement have not been established. We undertook this investigation to assess the incidence and time course of hematoma growth using objective cutoff values. METHODS:We reviewed the clinical records of 204 patients with spontaneous intracerebral hem...

journal_title：Stroke

authors： Kazui S,Naritomi H,Yamamoto H,Sawada T,Yamaguchi T

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Optimizing prehospital stroke care is important because effective treatments for acute stroke require a narrow therapeutic time window. We developed a smartphone-assisted prehospital medical information system (SPMIS) to facilitate research on prehospital stroke care. METHODS:Prehospital medical...

journal_title：Stroke

authors： Nakae T,Kataoka H,Kuwata S,Iihara K

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to investigate the feasibility and therapeutic effect of external counterpulsation (ECP) in ischemic stroke. METHODS:The trial was a randomized, crossover, assessment-blinded, proof-of-concept trial. ECP treatment consisted of 35 daily 1-hour sessions. Patients were randomized to either...

journal_title：Stroke

authors： Han JH,Leung TW,Lam WW,Soo YO,Alexandrov AW,Mok V,Leung YF,Lo R,Wong KS

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Numerous studies indicate that mild hypothermia provides substantial neuroprotection. However, current systems transfer insufficient heat to rapidly vary core temperature. We thus evaluated the safety and efficacy of endovascular cooling and rewarming for the induction and reversal of hypothermia...

journal_title：Stroke

authors： Dae MW,Gao DW,Ursell PC,Stillson CA,Sessler DI

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pediatric stroke, birth to 18 years, is a significant cause of long-term disability in the United States; however, there is currently little experimental data on the pathophysiology of childhood stroke owing to lack of animal models. We developed a novel mouse model of experimental childhood-onse...

journal_title：Stroke

authors： Herson PS,Bombardier CG,Parker SM,Shimizu T,Klawitter J,Klawitter J,Quillinan N,Exo JL,Goldenberg NA,Traystman RJ

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recovery of upper-limb motor impairment after first-ever ischemic stroke is proportional to the degree of initial impairment in patients with a functional corticospinal tract (CST). This study aimed to investigate whether proportional recovery occurs in a more clinically relevant sample including...

journal_title：Stroke

authors： Stinear CM,Byblow WD,Ackerley SJ,Smith MC,Borges VM,Barber PA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron overload has been associated with greater oxidative stress and brain injury in experimental cerebral ischemia and reperfusion. This study investigates whether high serum ferritin levels, as an index of increased cellular iron stores, are associated with poor outcome, hemorrhagic transformati...

journal_title：Stroke

authors： Millan M,Sobrino T,Castellanos M,Nombela F,Arenillas JF,Riva E,Cristobo I,García MM,Vivancos J,Serena J,Moro MA,Castillo J,Dávalos A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to clarify the association of chronic kidney disease (CKD) with carotid atherosclerosis and the impact of CKD on carotid atherosclerosis according to blood pressure categories in an urban general population. METHODS:We studied 3466 Japanese individuals (35-93 years old) in the Suita Stu...

journal_title：Stroke

authors： Ohara T,Kokubo Y,Toyoda K,Watanabe M,Koga M,Nakamura S,Nagatsuka K,Minematsu K,Nakagawa M,Miyamoto Y

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pending the results of randomized controlled trials, the benefit and safety of bridging therapy (combined intravenous and intra-arterial thrombolysis) remain to be determined. The aim of this analysis was to give reliable estimates of efficacy and safety outcomes of bridging therapy. METHODS:We ...

journal_title：Stroke

authors： Mazighi M,Meseguer E,Labreuche J,Amarenco P

更新日期：2012-05-01 00:00:00

abstract：:Clinical and pathologic observations have suggested analogies between the developing nervous system of ferrets (Mustela putorius furo) and those of more traditional animal models employed in stroke research. Experimental work has demonstrated advantages of the ferret as a model of visual development. We performed in v...

journal_title：Stroke

authors： Atkinson CS,Press GA,Lyden P,Katz B

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:While it has been widely reported that the vasospasm following subarachnoid hemorrhage (SAH) is prevented/reversed by endothelin (ET) receptor antagonists selective for the ET(A) receptor and by nonselective ET receptor antagonists, ie, antagonists of both the ET(A) and ET(B) receptors, there are...

journal_title：Stroke

authors： Zuccarello M,Boccaletti R,Romano A,Rapoport RM

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to investigate by means of transcranial Doppler (TCD) ultrasonography how many spontaneous reperfusions of the middle cerebral artery (MCA) occurred during the first week after onset of acute ischemic stroke in the carotid territory. METHODS:TCD examination, computed to...

journal_title：Stroke

authors： Zanette EM,Roberti C,Mancini G,Pozzilli C,Bragoni M,Toni D

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess the reproducibility, interobserver variability, and application to clinical studies of a new method for the quantitative assessment of carotid plaque echogenicity. METHODS:Carotid plaques were scanned with the use of ultrasound, and their images were stored in a computer. The...

journal_title：Stroke

authors： Sabetai MM,Tegos TJ,Nicolaides AN,Dhanjil S,Pare GJ,Stevens JM

更新日期：2000-09-01 00:00:00

abstract：:Hyperventilation to extremely low arterial carbon dioxide tension (PaCO2) has been used in the management of persistent pulmonary hypertension in newborn infants. With progressive hypocarbia, cerebral vasoconstriction occurs, raising the concern that extreme hypocarbia may result in cerebral oxygen deprivation. Theref...

journal_title：Stroke

authors： Rosenberg AA

更新日期：1988-11-01 00:00:00

abstract：:Using a scintillation camera system, hemispheric and regional cerebral blood flow was measured repeatedly during the course after a stroke. In 20 patients who improved clinically mean hemispheric and regional flow and relative weight of rapidly perfused compartment increased, while these values decreased in 15 patient...

journal_title：Stroke

authors： Heiss WD,Zeiler K,Turnheim M,Podreka I

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to investigate the direct costs of acute hospitalization for patients with first-ever ischemic stroke in Taiwan. METHODS:Data were prospectively collected from 360 first-ever ischemic stroke patients. Hospital charges were used for analysis. Multiple linear regression analysis was used...

journal_title：Stroke

authors： Chang KC,Tseng MC

更新日期：2003-11-01 00:00:00

abstract：:Though unilateral blood distribution of the vertebral artery has not been studied in humans, it is significant when considering the ischemic events especially embolic occlusion in vertebrobasilar system. To clarify the blood distribution, Krypton-81m was continuously infused into the vertebral arteries of 10 patients....

journal_title：Stroke

authors： Taki W,Handa H,Higa T,Tanada S,Fukuyama H,Fujita T,Yonekawa Y,Kameyama M,Torizuka K

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In Rivaroxaban Once Daily Oral Direct Factor Xa Inhibitor Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial, rivaroxaban was noninferior to dose-adjusted warfarin in preventing stroke or systemic embolism among patients with no...

journal_title：Stroke

authors： Wong KS,Hu DY,Oomman A,Tan RS,Patel MR,Singer DE,Breithardt G,Mahaffey KW,Becker RC,Califf R,Fox KA,Berkowitz SD,Hacke W,Hankey GJ,Executive Steering Committee and the ROCKET AF Study Investigators.

更新日期：2014-06-01 00:00:00

abstract：:To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...

journal_title：Stroke

authors： Lyden PD,Zivin JA,Kochhar A,Mazzarella V

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preischemic spontaneous locomotor activity was distinguished in this laboratory as a factor influencing outcome after 15 and 20 minutes of forebrain ischemia in gerbils. Histological investigations were carried out to analyze potential relations between postischemic survival and a reduction of ce...

journal_title：Stroke

authors： Stummer W,Weber K,Tranmer B,Baethmann A,Kempski O

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To clarify diagnostic entities in ischemic stroke we analyzed the relation between the severity of carotid atherosclerosis, coagulation parameters, lipoproteins, neurological status, and risk factors in 232 patients. METHODS:Duplex ultrasonography, computed tomography scan, and laboratory invest...

journal_title：Stroke

authors： Szirmai IG,Kamondi A,Magyar H,Juhász C

更新日期：1993-12-01 00:00:00

abstract：:Mild hypothermia is an established neuroprotectant in the laboratory, showing remarkable and consistent effects across multiple laboratories and models of brain injury. At the clinical level, mild hypothermia has shown benefits in patients who have experienced cardiac arrest and in some pediatric populations experienc...

journal_title：Stroke

authors： Yenari MA,Hemmen TM

更新日期：2010-10-01 00:00:00

abstract：:In an attempt to elucidate the mechanism by which hypertension acts as a risk factor for major non-haemorrhagic stroke, its effect on the prevalence of carotid atheroma has been studied angiographically. The carotid angiograms of 269 patients with cerebral tumours have been reviewed for evidence of coincidental athero...

journal_title：Stroke

authors： Harrison MJ,Wilson LA

更新日期：1983-07-01 00:00:00

abstract：:Background and Purpose- If a relationship between stroke etiology and thrombus computed tomography characteristics exists, assessing these characteristics in clinical practice could serve as a useful additional diagnostic tool for the identification of stroke subtype. Our purpose was to study the association of stroke...

journal_title：Stroke

authors： Boodt N,Compagne KCJ,Dutra BG,Samuels N,Tolhuisen ML,Alves HCBR,Kappelhof M,Lycklama À Nijeholt GJ,Marquering HA,Majoie CBLM,Lingsma HF,Dippel DWJ,van der Lugt A,Coinvestigators MR CLEAN Registry.

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolytic treatment of stroke carries the risk of hemorrhagic transformation. Therefore, the potential of MRI for prediction of recombinant tissue plasminogen activator (rtPA)-induced bleeding is explored to identify patients in whom rtPA treatment may provoke such complications. METHODS:Spon...

journal_title：Stroke

authors： Neumann-Haefelin C,Brinker G,Uhlenküken U,Pillekamp F,Hossmann KA,Hoehn M

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is currently no consensus on (1) the percentage of patients who develop spasticity after ischemic stroke, (2) the relation between spasticity and initial clinical findings after acute stroke, and (3) the impact of spasticity on activities of daily living and health-related quality of life. ...

journal_title：Stroke

authors： Urban PP,Wolf T,Uebele M,Marx JJ,Vogt T,Stoeter P,Bauermann T,Weibrich C,Vucurevic GD,Schneider A,Wissel J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although family studies have suggested a genetic influence on hemorrhagic stroke, the underlying genetic risk factors remain poorly defined. Coagulation factor XIII, which is involved in hemostasis, fibrinolysis, vascular remodeling, and tissue repair, represents a candidate gene for hemorrhagic ...

journal_title：Stroke

authors： Reiner AP,Schwartz SM,Frank MB,Longstreth WT Jr,Hindorff LA,Teramura G,Rosendaal FR,Gaur LK,Psaty BM,Siscovick DS

更新日期：2001-11-01 00:00:00