Differences between ischemic stroke subtypes in vascular outcomes support a distinct lacunar ischemic stroke arteriopathy: a prospective, hospital-based study.

abstract：BACKGROUND AND PURPOSE:The risk of stroke and death in patients with atrial fibrillation is strongly associated with age and concomitant comorbidities. The aim of this study was to examine the age dependence of risk factors for stroke and mortality in young patients with atrial fibrillation. METHODS:This study is a po...

journal_title：Stroke

authors： Melgaard L,Rasmussen LH,Skjøth F,Lip GY,Larsen TB

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The CHA2DS2-VASc score aims to improve risk stratification of ischemic stroke among patients with atrial fibrillation to identify those who can safely forego oral anticoagulation. Oral anticoagulation treatment guidelines remain uncertain for CHA2DS2-VASc score of 1. We conducted a systematic rev...

journal_title：Stroke

authors： Joundi RA,Cipriano LE,Sposato LA,Saposnik G,Stroke Outcomes Research Working Group.

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The goal of this study was to characterize cortical reorganization after stroke and its relation with the site of the stroke-induced lesion and degree of motor recovery using functional MRI (fMRI). METHODS:Fourteen stroke patients with an affected upper limb were studied longitudinally. Three fM...

journal_title：Stroke

authors： Feydy A,Carlier R,Roby-Brami A,Bussel B,Cazalis F,Pierot L,Burnod Y,Maier MA

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to determine the effect of intracisternal administration of an endothelin-A receptor antagonist (BQ-123) against vasospasm in a monkey model and to determine whether this drug would have adverse interactions with intracisternal tissue plasminogen activator (TPA). METHODS:Thirty-three mo...

journal_title：Stroke

authors： Kim CJ,Bassiouny M,Macdonald RL,Weir B,Johns LM

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The relationship between diabetic retinopathy and ischemic stroke is uncertain and examined in this study. METHODS:A population-based, prospective cohort study of 1617 middle-aged persons with diabetes. Diabetic retinopathy signs were ascertained from retinal photographs, and incident ischemic s...

journal_title：Stroke

authors： Cheung N,Rogers S,Couper DJ,Klein R,Sharrett AR,Wong TY

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to evaluate the impact of new treatments by examining the changes between 1990 to 1991 and 2000 to 2001 in in-hospital mortality rates and hospital charges in adult patients with stroke. METHODS:From the Nationwide Inpatient Survey, the largest all-payer inpatient c...

journal_title：Stroke

authors： Qureshi AI,Suri MF,Nasar A,Kirmani JF,Ezzeddine MA,Divani AA,Giles WH

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In an inner-London teaching hospital, a randomized trial of "conventional" care versus early discharge to community-based therapy found no significant differences in clinical outcomes between patient groups. This report examines the economic consequences of the alternative strategies. METHODS:On...

journal_title：Stroke

authors： Beech R,Rudd AG,Tilling K,Wolfe CD

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is important to know the costs of hospitalization for patients undergoing endovascular embolectomy so that comparisons can be made with payments to hospitals. METHODS:Using the National Inpatient Sample, we evaluated the costs of hospitalization for patients treated with endovascular embolect...

journal_title：Stroke

authors： Brinjikji W,Kallmes DF,Rabinstein AA,Lanzino G,Cloft HJ

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke community surveillance projects often focus on hospital data rates. We hypothesized that not including strokes which occurred in nursing homes or at home would differentially affect race/ethnic stroke rates. METHODS:Texas vital statistics data were studied to compare age-specific (45 to 5...

journal_title：Stroke

authors： Wein TH,Smith MA,Morgenstern LB

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is proposed that 20% to 40% of the decline in first-ever stroke incidence is attributed to the improvement of risk factor control. We estimated the impact of modifiable cardiovascular risk factors on the changing incidence of ischemic stroke (IS) between 1995 and 2012, using individual person ...

journal_title：Stroke

authors： Vangen-Lønne AM,Wilsgaard T,Johnsen SH,Løchen ML,Njølstad I,Mathiesen EB

更新日期：2017-03-01 00:00:00

abstract：:Background and Purpose- Given inconclusive studies, it is debated whether clinical and imaging characteristics, as well as functional outcome, differ among patients with intracerebral hemorrhage (ICH) related to vitamin K antagonists (VKA) versus non-vitamin K antagonist (NOAC)-related ICH. Notably, clinical character...

journal_title：Stroke

authors： Gerner ST,Kuramatsu JB,Sembill JA,Sprügel MI,Hagen M,Knappe RU,Endres M,Haeusler KG,Sobesky J,Schurig J,Zweynert S,Bauer M,Vajkoczy P,Ringleb PA,Purrucker JC,Rizos T,Volkmann J,Müllges W,Kraft P,Schubert AL,Erbgut

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral microbleeds are frequently seen in the general elderly population, but it is unknown at what rate they occur with aging and whether once present can disappear over time. METHODS:As part of the Rotterdam Scan Study, 831 persons (mean age, 68.5 years) underwent repeated brain MRI with a m...

journal_title：Stroke

authors： Poels MM,Ikram MA,van der Lugt A,Hofman A,Krestin GP,Breteler MM,Vernooij MW

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have shown that acute treatment with candesartan in an experimental model of stroke resulted in vascular protection and improved outcomes at 24 hours poststroke, but the mechanisms are unknown. We now examine effects of candesartan on proangiogenic factors and 7-day outcomes using the same tre...

journal_title：Stroke

authors： Kozak A,Ergul A,El-Remessy AB,Johnson MH,Machado LS,Elewa HF,Abdelsaid M,Wiley DC,Fagan SC

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the physical and, to a lesser extent, emotional outcome of stroke survivors has been well documented, there are far fewer data relating to the outcomes of those who care for them. We aimed to describe the outcome of those caring for stroke patients and to identify both patient and caregi...

journal_title：Stroke

authors： Dennis M,O'Rourke S,Lewis S,Sharpe M,Warlow C

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Maternal cigarette smoking increases the risk of neonatal morbidity. We tested the hypothesis that perinatal nicotine exposure causes heightened brain vulnerability to hypoxic-ischemic (HI) injury in neonatal rats through aberrant expression patterns of angiotensin II type 1 (AT(1)R) and type 2 (...

journal_title：Stroke

authors： Li Y,Xiao D,Dasgupta C,Xiong F,Tong W,Yang S,Zhang L

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study is to assess whether the PHASES score allows to (1) match decisions taken by multidisciplinary team whether to observe or intervene, (2) classify patients being diagnosed with a ruptured versus unruptured intracranial aneurysm (UIA), and (3) discriminate patients at low risk...

journal_title：Stroke

authors： Bijlenga P,Gondar R,Schilling S,Morel S,Hirsch S,Cuony J,Corniola MV,Perren F,Rüfenacht D,Schaller K

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite the social, health, and economic burdens associated with cognitive impairment poststroke, there is considerable uncertainty about the types of interventions that might preserve or restore cognitive abilities. The objective of this systematic review and meta-analysis was to evaluate the ef...

journal_title：Stroke

authors： Oberlin LE,Waiwood AM,Cumming TB,Marsland AL,Bernhardt J,Erickson KI

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticoagulation is a highly effective secondary prevention in patients with cardioembolic stroke and atrial fibrillation/flutter (AF). However, the condition remains underdiagnosed, because paroxysmal AF may be missed by diagnostic tests in the acute phase. In this study, the sensitivity of AF de...

journal_title：Stroke

authors： Kallmünzer B,Breuer L,Hering C,Raaz-Schrauder D,Kollmar R,Huttner HB,Schwab S,Köhrmann M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) causes acute vasoconstriction that contributes to ischemic brain injury shortly after the initial bleed. It has been theorized that decreased availability of nitric oxide (NO) may contribute to acute vasoconstriction. Therefore we examined the effect of the NO donor ...

journal_title：Stroke

authors： Sehba FA,Ding WH,Chereshnev I,Bederson JB

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Using the dexamethasone suppression test, we studied the suppressibility of the cortisol axis and its clinical determinants at various time points after stroke. A major aim was to examine the dexamethasone test as a diagnostic tool for the diagnosis of major depression in stroke patients. METHOD...

journal_title：Stroke

authors： Aström M,Olsson T,Asplund K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:[18F]fluoromisonidazole (FMISO) positron emission tomography has been used to image hypoxia early after human stroke. To further study the role of hypoxia in stroke and the binding characteristics of FMISO, we aimed to develop [3H]FMISO autoradiography in an animal stroke model. We hypothesized t...

journal_title：Stroke

authors： Spratt NJ,Ackerman U,Tochon-Danguy HJ,Donnan GA,Howells DW

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The antiplatelet agent sarpogrelate is a selective inhibitor of 5-hydroxytryptamine receptors. The purpose of this study was to compare the efficacy and safety of sarpogrelate with those of aspirin in Japanese ischemic stroke patients. METHODS:In total, 1510 patients with recent cerebral infarct...

journal_title：Stroke

authors： Shinohara Y,Nishimaru K,Sawada T,Terashi A,Handa S,Hirai S,Hayashi K,Tohgi H,Fukuuchi Y,Uchiyama S,Yamaguchi T,Kobayashi S,Kondo K,Otomo E,Gotoh F,S-ACCESS Study Group.

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CT remains the most commonly used imaging technique in acute stroke but is often delayed after minor stroke. Interobserver reliability in distinguishing hemorrhagic transformation of infarction from intracerebral hemorrhage may depend on delays to CT but has not been reported previously despite t...

journal_title：Stroke

authors： Lovelock CE,Anslow P,Molyneux AJ,Byrne JV,Kuker W,Pretorius PM,Coull A,Rothwell PM

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Striatal GABAergic neuron is known as a key regulator in adult neurogenesis. However, the specific role of striatal GABAergic neuronal activity in the promotion of neurological recovery after ischemic stroke remains unknown. Here, we used optogenetic approach to investigate these effects and mech...

journal_title：Stroke

authors： Jiang L,Li W,Mamtilahun M,Song Y,Ma Y,Qu M,Lu Y,He X,Zheng J,Fu Z,Zhang Z,Yang GY,Wang Y

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke produces diaschisis in adjacent and connected regions. The sequential changes in diaschisis over time and the relationship of regions of diaschisis to functional cortical areas and regions of poststroke neuroplasticity have not been determined. METHODS:Small cortical strokes were produced...

journal_title：Stroke

authors： Carmichael ST,Tatsukawa K,Katsman D,Tsuyuguchi N,Kornblum HI

更新日期：2004-03-01 00:00:00

abstract：:As part of a prospective study of the neurologic and neuropsychological complications of coronary artery bypass graft surgery, 312 patients were compared with a control group of 50 patients undergoing major surgery for peripheral vascular disease. The purpose of comparing the 2 groups was to determine to what extent n...

journal_title：Stroke

authors： Shaw PJ,Bates D,Cartlidge NE,French JM,Heaviside D,Julian DG,Shaw DA

更新日期：1987-07-01 00:00:00

abstract：:The morphologic description and measurements of endarterectomy specimens are usually believed to be accurate and are used as the gold standard against which the findings of diagnostic procedures are judged. Pathology data on 289 endarterectomy specimens from five participating centers and the corresponding angiography...

journal_title：Stroke

authors： Schenk EA,Bond MG,Aretz TH,Angelo JN,Choi HY,Rynalski T,Gustafson NF,Berson AS,Ricotta JJ,Goodison MW

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A variety of primary end points have been used in acute stroke trials. We focus on the modified Rankin Scale, a reliable and valid ordinal outcome measure that assesses disability on a 7-point scale. METHODS:We provide an abbreviated discussion of analytical methods for ordinal scales, and relat...

journal_title：Stroke

authors： Koziol JA,Feng AC

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:With the advent of time-dependent thrombolytic therapy for ischemic stroke, it has become increasingly important for stroke patients to arrive at the hospital quickly. This study investigates the association between the use of emergency medical services (EMS) and delay time among individuals with...

journal_title：Stroke

authors： Schroeder EB,Rosamond WD,Morris DL,Evenson KR,Hinn AR

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The clinical syndrome of transient ischemic attacks is accompanied in a significant percentage of patients by brain lesions or neuroimaging abnormalities whose structural counterparts have not been defined. The objective of this study was to analyze, in an experimental model of short-term (< 25 m...

journal_title：Stroke

authors： Garcia JH,Liu KF,Ye ZR,Gutierrez JA

更新日期：1997-11-01 00:00:00