Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion.

abstract：BACKGROUND AND PURPOSE:The PIWI-interacting RNA (piRNA) is the most predominant RNA species in eukaryotes. The piRNA are a class of noncoding RNAs that bind and degrade the RNA formed by the transposons to control the transposon-induced gene mutations. The role of piRNA after focal ischemia is not yet evaluated. METHO...

journal_title：Stroke

authors： Dharap A,Nakka VP,Vemuganti R

更新日期：2011-04-01 00:00:00

abstract：:In an attempt to determine the usefulness of evoked potentials as a measure of focal cerebral ischemia, we examined somatosensory evoked potentials (SEP's) and morphological neuronal changes in cats following unilateral middle cerebral artery (MCA) occlusion. Fifteen adult cats underwent transorbital occlusion of the ...

journal_title：Stroke

authors： Steinberg GK,Gelb AW,Lam AM,Manninen PH,Peerless SJ,Rassi Neto A,Floyd P

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To improve reproducibility and reliability in the identification of embolic signals detected with the use of Doppler ultrasound, many studies have used an intensity threshold. However, variable thresholds between 3 and 12 dB have been used, and often the method of measurement of intensity is not ...

journal_title：Stroke

authors： Markus HS,Molloy J

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid endarterectomy reduces the risk of carotid territory ischemic stroke ipsilateral to a recently symptomatic severe carotid stenosis. However, the benefit is limited by the risks of stroke and death associated with the operation. Although reported surgical risks vary enormously, there has b...

journal_title：Stroke

authors： Rothwell PM,Slattery J,Warlow CP

更新日期：1996-02-01 00:00:00

abstract：:One hundred and sixteen carotid artery bruits were assessed using quantitative phonoangiography (spectral bruit analysis - SBA). This technique uses the averaged break frequency of the bruit to calculate the diameter of he residual lumen at the site of stenosis. Biplanar contrast arteriography was performed on 43 (37%...

journal_title：Stroke

authors： Knox R,Breslau P,Strandness DE Jr

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia is a common stroke symptom and leads to serious complications such as aspiration and pneumonia. Early dysphagia screening can reduce these complications. In many hospitals, dysphagia screening is performed by speech-language therapists who are often not available on weekends/holidays, w...

journal_title：Stroke

authors： Palli C,Fandler S,Doppelhofer K,Niederkorn K,Enzinger C,Vetta C,Trampusch E,Schmidt R,Fazekas F,Gattringer T

更新日期：2017-09-01 00:00:00

abstract：:A retrospective study of 141 patients whith ischemic brain stem infarction admitted to the Department of Neurology, University of Helsinki, during 1966 to 1973 was performed. The patients were contacted by mail in January and February, 1974; in case of death, the death certificates were procured. The follow-up period ...

journal_title：Stroke

authors： Fogelhol R,Aho K

更新日期：1975-05-01 00:00:00

abstract：:The frequency of angiographically defined asymptomatic CAD in patients with carotid disease is 40%. Although the prognosis of patients with asymptomatic 1-vessel or 2-vessel CAD is good (annual cardiac mortality rate less than 2%), the prognosis of asymptomatic 3-vessel disease or left main CAD is substantially less f...

journal_title：Stroke

authors： Chimowitz MI,Mancini GB

更新日期：1992-03-01 00:00:00

abstract：:Experimental subarachnoid hemorrhage was induced in 52 adult male Wistar rats by microsurgical transclival basilar artery puncture. Telencephalic blood flow measured in 24 rats with subarachnoid hemorrhage was compared with that in 23 sham-operated rats and 10 unoperated control rats using the [14C]butanol indicator f...

journal_title：Stroke

authors： Kader A,Krauss WE,Onesti ST,Elliott JP,Solomon RA

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Intravenous Nimodipine West European Stroke Trial (INWEST) found a correlation between nimodipine-induced reduction in blood pressure (BP) and an unfavorable outcome in acute stroke. We sought to confirm this correlation with and without adjustment for prognostic variables and to investigate ...

journal_title：Stroke

authors： Ahmed N,Näsman P,Wahlgren NG

更新日期：2000-06-01 00:00:00

abstract：:The effects of halothane on intracellular membrane potential (Em) and force development in cat MCA were studied. Halothane (0.07-0.14 mM/1) relaxed isolated MCA which had developed myogenic tone. Measurement of Em showed that halothane depolarized this preparation in a dose-dependent fashion in the face of vessel rela...

journal_title：Stroke

authors： Harder DR,Gradall K,Madden JA,Kampine JP

更新日期：1985-07-01 00:00:00

abstract：:Arteriolar diameters and venular erythrocyte velocities in the small pial vessels on the surface of the cat brain were measured by TV methods during induced epileptic seizures through a cranial window. Grand mal seizures maximally dilated arterioles and increased venular erythrocyte velocity up to 400%. High positive ...

journal_title：Stroke

authors： Myers RR,Intaglietta M

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to establish the pattern of blood pressure (BP) change after hospitalization for acute hemispheric stroke. METHODS:In 292 patients from the Leicester teaching hospitals with acute hemispheric stroke within the previous 24 hours (139 men; median age, 75 years [range, 42 to 98 years]), w...

journal_title：Stroke

authors： Harper G,Castleden CM,Potter JF

更新日期：1994-09-01 00:00:00

abstract：:Background and Purpose- Stroke is the most frequent severe clinical event in patients with Fabry disease. We aimed to evaluate the cerebral magnetic resonance imaging findings of patients with Fabry disease and assess their association with future stroke risk after enzyme replacement therapy (ERT) induction. Methods- ...

journal_title：Stroke

authors： Yagita Y,Sakai N,Miwa K,Ohara N,Tanaka M,Sakaguchi M,Kitagawa K,Mochizuki H

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hyperglycemia enhances the deleterious effect of global cerebral ischemia. One possible explanation is that increased anaerobic glycolysis leads to exaggeration of intracellular acidosis and increased postischemic edema. To examine the importance of this edema on postischemic cerebral perfusion d...

journal_title：Stroke

authors： Morimoto Y,Morimoto Y,Warner DS,Pearlstein RD

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to determine clinical and hemodynamic predictors of early reocclusion (RO) in stroke patients treated with intravenous tissue plasminogen activator (tPA). METHODS:We studied 142 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with intravenous...

journal_title：Stroke

authors： Rubiera M,Alvarez-Sabín J,Ribo M,Montaner J,Santamarina E,Arenillas JF,Huertas R,Delgado P,Purroy F,Molina CA

更新日期：2005-07-01 00:00:00

abstract：:Background and Purpose- Hypertrophic cardiomyopathy patients with atrial fibrillation are at increased risk of stroke, and anticoagulation is strongly recommended. However, limited data are available regarding the safety and effectiveness of non-vitamin K antagonist oral anticoagulants (NOACs) for primary prevention o...

journal_title：Stroke

authors： Lee HJ,Kim HK,Jung JH,Han KD,Lee H,Park JB,Kim HM,Kim YJ,Ommen SR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To date, few studies have examined associations between the wide range of flavonoid subclasses and risk of ischemic, hemorrhagic, and total stroke. METHODS:We conducted a prospective study among 69 622 women from the Nurses' Health Study. Total flavonoid and subclass intakes were calculated from...

journal_title：Stroke

authors： Cassidy A,Rimm EB,O'Reilly EJ,Logroscino G,Kay C,Chiuve SE,Rexrode KM

更新日期：2012-04-01 00:00:00

abstract：:Feline pial arteries larger than 100 mu in diameter constricted in response to cervical sympathetic nerve stimulation suggests or in response to topical application of norepinephrine. Smaller pial arteries were unresponsive to norepinephrine. This unresponsiveness persisted when norepinephrine was dissolved in CSF wit...

journal_title：Stroke

authors： Wei EP,Raper AJ,Kontos HA,Patterson JL Jr

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:TIMI angiographic classification measures coronary residual flow and recanalization. We developed a Thrombolysis in Brain Ischemia (TIBI) classification by using transcranial Doppler (TCD) to noninvasively monitor intracranial vessel residual flow signals. We examined whether the emergent TCD TIB...

journal_title：Stroke

authors： Demchuk AM,Burgin WS,Christou I,Felberg RA,Barber PA,Hill MD,Alexandrov AV

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Current guidelines suggest that cardiac arrest (CA) survivors should be ventilated with 100% O(2) after resuscitation. Breathing 100% O(2) may worsen neurological outcome after experimental CA. This study tested the hypothesis that graded reoxygenation, with oximetry guidance, can safely reduce F...

journal_title：Stroke

authors： Balan IS,Fiskum G,Hazelton J,Cotto-Cumba C,Rosenthal RE

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We studied whether the inducible nitric oxide synthase (iNOS) inhibitor aminoguanidine reduces focal cerebral ischemic damage in a relatively noninvasive stroke model in which the rat middle cerebral artery (MCA) is occluded using an intravascular filament. METHODS:In rats anesthetized with halo...

journal_title：Stroke

authors： Zhang F,Casey RM,Ross ME,Iadecola C

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral emboli can be identified by the presence of typical microembolic signals (MES) in transcranial Doppler (TCD) spectral curves. The usefulness of this technique was studied by evaluating the prevalence and time course of MES in patients with acute stroke. In addition, we examined the influ...

journal_title：Stroke

authors： Sliwka U,Lingnau A,Stohlmann WD,Schmidt P,Mull M,Diehl RR,Noth J

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A close correlation between B-mode sonography and the histopathology and surface structure of plaque is rarely seen in vivo with high-grade stenoses of the extracranial carotid artery. The goal of this study was to determine whether normalized gray scale analysis and surface analysis of the plaqu...

journal_title：Stroke

authors： Denzel C,Balzer K,Müller KM,Fellner F,Fellner C,Lang W

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the stroke rate associated with atrial fibrillation has declined over the last 10 years, the emerging atrial fibrillation epidemic threatens to increase the incidence of cardioembolic stroke. Summary of Review-Oral anticoagulants are superior antithrombotic agents but are underused due t...

journal_title：Stroke

authors： Medi C,Hankey GJ,Freedman SB

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral arteries develop stretch-induced myogenic tone, which plays an important role in the regulation of blood flow to the brain. Although the effect of oxidized LDL (Ox-LDL) on many aspects of the vascular endothelial and smooth muscle cell function have been extensively investigated, its inf...

journal_title：Stroke

authors： Xie H,Bevan JA

更新日期：1999-11-01 00:00:00

abstract：:Spontaneously hypertensive rats (SHR) have been shown to have an increased capacity for superior cervical sympathetic nerve activity which may protect against stroke (Mueller et al: Stroke 13: 115, 1982). Sympathetic nerve activity has never been examined in the stroke-prone substrain of SHR (SP). In this study we mea...

journal_title：Stroke

authors： Mueller SM,Black WL Jr

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study aims to investigate the association between insulin resistance (IR) and silent lacunar infarction (SLI) in healthy adults. METHODS:We recruited 2326 healthy Korean adults who took health checkups, including a brain magnetic resonance imaging. SLI was defined as an infarction measuring...

journal_title：Stroke

authors： Lee JE,Shin DW,Yun JM,Kim SH,Nam YS,Cho B,Lim JS,Jeong HY,Kwon HM,Park JH

更新日期：2016-12-01 00:00:00

abstract：:Cerebral ischemic events associated with arteriography are usually attributed to catheter-induced emboli. We present three patients with cerebral ischemia occurring 6 to 48 hours post-arteriography. We suspected that alternate pathogenic mechanisms were in effect. To evaluate the possibility that sustained platelet ac...

journal_title：Stroke

authors： Fisher M,Sandler R,Weiner JM

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lamotrigine (LTG) is an anticonvulsant drug whose mechanism of action may involve the inhibition of glutamate release by blocking voltage-dependent sodium channels. Glutamate neurotoxicity may contribute to cerebral ischemic damage after recovery from cardiac arrest. Thus, LTG may prevent the bra...

journal_title：Stroke

authors： Crumrine RC,Bergstrand K,Cooper AT,Faison WL,Cooper BR

更新日期：1997-11-01 00:00:00