Abstract:
BACKGROUND AND PURPOSE:An association between high lipoprotein(a) [Lp(a)] levels and positive Chlamydia pneumoniae IgG titers in coronary artery disease has been described. The possibility of predicting ischemic stroke by measurements of plasma Lp(a) and C pneumoniae antibodies was investigated. METHODS:This incident case-control study included 101 case subjects (cases) who had suffered ischemic cerebral infarctions and 201 matched control subjects (controls). The study population was nested within the Västerbotten Intervention Program or the WHO MONICA project. Plasma samples were measured for C pneumoniae-specific IgG and IgA antibodies and Lp(a). RESULTS:A significantly higher mean Lp(a) level was found in female cases than in female controls. However, plasma Lp(a) was unable to predict ischemic cerebral infarctions in either women or men. The proportion of individuals with positive C pneumoniae-specific IgG or IgA titers did not differ between cases and controls. Antibody titers were unable to predict a future stroke. The proportion of individuals with a positive C pneumoniae IgG titer in combination with a high Lp(a) level did not differ significantly between cases and controls. CONCLUSIONS:These data suggest that there is no association between baseline plasma Lp(a) levels, presence of C pneumoniae antibodies, and future ischemic cerebral infarctions. Furthermore, no evidence of an interactive effect between high Lp(a) levels and C pneumoniae IgG titers was found. However, selection bias and a recent C pneumoniae epidemic may have influenced the results.
journal_name
Strokejournal_title
Strokeauthors
Glader CA,Stegmayr B,Boman J,Stenlund H,Weinehall L,Hallmans G,Dahlén GHdoi
10.1161/01.str.30.10.2013subject
Has Abstractpub_date
1999-10-01 00:00:00pages
2013-8issue
10eissn
0039-2499issn
1524-4628journal_volume
30pub_type
临床试验,杂志文章,随机对照试验相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Perihematomal edema (PHE) is associated with poor outcomes after intracerebral hemorrhage (ICH). PHE evolves in the early period after ICH, providing a therapeutic target and window for intervention. We studied the effect of PHE volume expansion in the first 72 hours (iPHE) and its relationship w...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.115.010054
更新日期:2015-11-01 00:00:00
abstract::Background and Purpose- The simplified stroke-thrombolytic predictive instrument (s-Stroke-TPI) is useful for predicting the outcomes in thrombolysis-treated patients in Western populations. We aimed to validate its predictive value in Chinese patients. Methods- Data from thrombolysis implementation and monitor of acu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.022269
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In malignant cerebral venous thrombosis (CVT) patients, emergency decompressive surgery has been suggested as a life-saving procedure. We report 12 patients with malignant CVT, among whom 8 underwent operation. METHODS:Retrospective study of 12 patients from 3 stroke units who had a malignant CV...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.572909
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Repetitive transcranial magnetic stimulation of the primary motor cortex (M1) may improve outcomes after stroke. The aim of this study was to determine the effects of M1 theta burst stimulation (TBS) and standardized motor training on upper-limb function of patients with chronic stroke. METHODS:...
journal_title:Stroke
pub_type: 信件
doi:10.1161/STROKEAHA.110.583278
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:[123I]Iomazenil is a specific radioligand for the central benzodiazepine receptor that may be useful as an indicator of the intactness of cortical neurons after focal cerebral ischemia. We evaluated the binding of this receptor in reperfused cortex among patients with ischemic stroke to detect vi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.1.124
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Middle cerebral artery (MCA) stenosis is a relatively rare occlusive disease with an annual stroke risk of approximately 7% to 8%. However, the frequent coincidence of cardiac or ipsilateral carotid artery disease may lead to difficulties in identifying the relevant embolizing source in symptomat...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.8.1347
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:A number of studies have shown that reduced intrauterine growth and low birth weight are associated with raised rates of fatal and nonfatal stroke in adult life. Whether this increased risk of stroke is modified by growth in childhood or by socioeconomic status in adult life is not known. METHOD...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.31.4.869
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke is a major cause of death in the People's Republic of China (PRC), and the geographic distribution of stroke death varies substantially. We conducted an ecological analysis to investigate the relationship of prevalence of hypertension and other risk factors with stroke incidence and mortal...
journal_title:Stroke
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Multicenter clinical trials attempt to select sites that can move rapidly to randomization and enroll sufficient numbers of patients. However, there are few assessments of the success of site selection. METHODS:In the CREST-2 (Carotid Revascularization and Medical Management for Asymptomatic Car...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.016976
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The ABC/2 method for calculating intracerebral hemorrhage (ICH) volume has been well validated. However, the formula, derived from the volume of an ellipse, assumes the shape of ICH is elliptical. We sought to compare the agreement of the ABC/2 formula with other methods through retrospective ana...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.016677
更新日期:2018-02-01 00:00:00
abstract::We evaluated the effects of aging and hypertension on endothelium-dependent relaxation of rat common carotid arteries using 14-week-old (young) and 11-month-old (old) Wistar-Kyoto rats (WKY) and age-matched spontaneously hypertensive rats (SHR). Isometric tension of common carotid artery ring segments was measured. Wi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.7.892
更新日期:1988-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The presence of known restriction fragment length polymorphisms in the apoprotein A-I-C-III gene cluster, which encodes their respective apoproteins, was investigated using the restriction enzymes Sac I and Pst I to determine the potential role of genetic variations for stroke risk in an American...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.9.1257
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:cerebral small vessel disease (SVD) is the most common cause of vascular dementia. Interest in the use of surrogate markers is increasing. The aims of this study were to determine if brain volume was different between patients with SVD and control subjects, whether it correlated with cognition in...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.594267
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke symptoms can be very stressful for family caregivers, but most knowledge about the prevalence and stressfulness of stroke-related patient problems is derived from convenience samples. In addition, little is known about perceived benefits of the stroke caregiving experience. The purpose of ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.108.545269
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Previous studies exploring stroke-related caregiving focused solely on informal caregiving and a relatively limited set of activities. We sought to determine whether, and at what cost, stroke survivors receive more care than matched controls using an expanded definition of caregiving and inclusio...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.012704
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intracranial internal carotid artery calcification is associated with cerebrovascular risk factors and stroke, but few quantification methods are available. We tested the reliability of visual scoring, semiautomated Agatston score, and calcium volume measurement in patients with recent stroke. M...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.115.009716
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Previously, we have shown that hyperthermia significantly increased neuronal damage after ischemic injury in a focal embolic model of stroke in rats. In the present study, we examined the effects of hyperthermia on the efficacy of thrombolytic therapy in this stroke model. METHODS:In part A, eff...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000155684.20864.58
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Increased amount of therapy seems to be beneficial for motor recovery after stroke. The primary aim of the present study was to evaluate the effect of a 4-week community-based intensive motor training program combined with early supported discharge after initial treatment in a comprehensive strok...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.110.584284
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Randomized clinical trials testing aspirin in relatively low-risk, middle-aged people have consistently shown small increases in stroke associated with aspirin use. We analyzed the relationship between the regular use of aspirin and incident ischemic and hemorrhagic stroke among people aged 65 ye...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1161/01.str.29.5.887
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Accurate data on the distribution of stroke subtypes are essential for understanding the forces driving recent morbidity and mortality trends. The introduction of diagnosis-related groups (DRGs) in the 1980s may have affected the distribution of stroke subtypes as defined by International Classif...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.32.7.1487
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In animal models of cerebral ischemia, matrix metalloproteinase (MMP) expression was significantly increased and related to blood-brain barrier disruption, edema formation, and hemorrhagic transformation (HT). MMP inhibitors reduce HT after embolic ischemia in tissue-type plasminogen activator-tr...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/hs1201.99512
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Acupuncture may be a promising treatment for poststroke paralysis. We conducted a meta-analysis, assessing the efficacy of acupuncture with and without stroke rehabilitation. METHODS:We identified randomized trials comparing acupuncture with no acupuncture within 6 months of stroke by searching ...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/01.str.0000035908.74261.c9
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The presence of white-matter hyperintensities (WMHs) has been linked to intracerebral hemorrhage (ICH). We sought to determine whether the severity of WMHs influences hematoma growth and ICH volume. METHODS:We retrospectively reviewed prospectively collected clinical, laboratory, and radiologic ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.564955
更新日期:2010-01-01 00:00:00
abstract::Background and Purpose- Hemispheric stroke studies associating lateropulsion (pusher syndrome) with the location of brain lesions have had mixed results from small, unmatched samples. This study was designed to determine whether lateropulsion localizes to specific brain regions across patients with stroke using a case...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.023445
更新日期:2019-05-01 00:00:00
abstract::Cerebral cortical blood flow was measured in rabbits with the hydrogen clearance technique. The reactivity to CO2, tested by changing the end tidal CO2 (ETCO2) in steps from 2 to 6 volumes %, was highly dependent on the kind of anesthesia, being greatest under halothane and least under nitrous oxide. Reactivity to CO2...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.9.2.160
更新日期:1978-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stent-assisted coiling has expanded the treatment of intracranial aneurysms, but the rates of procedure-related neurological complications and the incidence of angiographic aneurysm recurrence of this novel treatment are not yet well known. We present our experience with stent-assisted coiling wi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.558114
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:This study was conducted to analyze the association between reported risk factors for Alzheimer's disease, apolipoprotein E epsilon4 allele, and cardiovascular disease and neuropathological changes essential for the diagnosis of Alzheimer's disease. METHODS:Our data are based on clinical and pos...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.3.613
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The role of extracellular Ca2+ in the maintenance of chronic vasospasm after subarachnoid hemorrhage (SAH) is largely unknown. Indeed, studies thus far have been limited to demonstrations that L-type Ca(2+)-channel antagonists were unable to reverse the spasm. This study tested whether SAH-induce...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.10.1896
更新日期:1996-10-01 00:00:00
abstract::Experimental regional cerebral ischemia was produced in the middle cerebral artery (MCA) territory in primates (M. mulatta) by macrosphere embolization. Determinations of percentage tissue dry weight and tissue sodium and potassium concentrations were obtained in samples from the ischemic and non-ischemic hemispheres ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.9.4.387
更新日期:1978-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Some strokes of unknown etiology may be the result of a paradoxical embolism traversing through a nonfused foramen ovale (patent foramen ovale [PFO]). The utility of percutaneously placed devices for treatment of patients with cryptogenic stroke or transient ischemic attack (TIA) and PFO is unkno...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/STROKEAHA.110.593376
更新日期:2010-12-01 00:00:00