Abstract:
:A maximum clade credibility tree constructed using the full-length spike (S) and hemagglutinin-esterase genes revealed that Vietnamese Bovine coronavirus (BCoV) strains belong to a single cluster (C1); therefore, they might share a common origin with Cuban and Chinese BCoV strains. The omega values of cluster 1 (C1) and cluster 2 (C2) were 0.15734 and 0.11613, respectively, and naive empirical bayes analysis identified two amino acid positions (179 and 501) in the S protein in C1 and three amino acid positions (113, 501, and 525) in that of C2 that underwent positive selection (p > 99%). The evolutionary rate of C1 was estimated to be 7.6206 × 10-4 substitutions/site/year, and the most recent common ancestor (tMRCA) of Vietnamese BCoVs was estimated to date back to 1962 (95% HPD 1950-1973). The effective population sizes of C1 and C2 underwent a rapid reduction after 2000 and 2004, respectively.
journal_name
Virus Genesjournal_title
Virus genesauthors
Shin J,Tark D,Le VP,Choe S,Cha RM,Park GN,Cho IS,Nga BTT,Lan NT,An DJdoi
10.1007/s11262-019-01647-1subject
Has Abstractpub_date
2019-06-01 00:00:00pages
415-420issue
3eissn
0920-8569issn
1572-994Xpii
10.1007/s11262-019-01647-1journal_volume
55pub_type
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