Genetic relationship of Borna disease virus isolates.

Abstract:

:The infection of humans with Boma disease virus (BDV) is still a matter of debate. In a recent publication, we described a BDV (RW98) isolated from the blood of a psychiatric patient. The RNA of this virus differed more than 5% from that of the widely used strain He/80, which was supposed to represent our laboratory virus. Here, we show that the virus used in our laboratory was not He/80 and, furthermore, that RW98 has sequence identity to the laboratory strain. We also present data that BDV-specific nucleic acid detected in blood of the donor of the presumed RW98 isolate and one other patient differs from all known BDV-p24 sequences, arguing for the existence of BDV sequences in man.

journal_name

Virus Genes

journal_title

Virus genes

authors

Planz O,Rziha HJ,Stitz L

doi

10.1023/a:1022321920287

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

25-30

issue

1

eissn

0920-8569

issn

1572-994X

journal_volume

26

pub_type

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