Adaptation of wild-type measles virus to cotton rat lung cells: E89K mutation in matrix protein contributes to its fitness.

abstract：:Proteins harbor domains or short linear motifs, which facilitate their functions and interactions. Finding functional motifs in protein sequences could predict the putative cellular roles or characteristics of hypothetical proteins. In this study, we present Shetti-Motif, which is an interactive tool to (i) map UniPro...

journal_title：Virus genes

authors： Sobhy H

更新日期：2017-04-01 00:00:00

abstract：:Sapoviruses (SaVs) are enteric viruses and have been detected in various mammals. They are divided into multiple genogroups and genotypes based on the entire major capsid protein (VP1) encoding region sequences. In this study, we determined the first complete genome sequences of two genogroup V, genotype 3 (GV.3) SaV ...

journal_title：Virus genes

authors： Oka T,Doan YH,Shimoike T,Haga K,Takizawa T

更新日期：2017-12-01 00:00:00

abstract：:Spodoptera litura multicapsid nucleopolyhedrovirus (SpltMNPV) odv-e25 is 684 bp long, potentially encoding 227 amino acids with a predicted molecular weight of 24.9 kDa. Homology analysis indicated that SpltMNPV ODV-E25 has 35-65% amino acid identity with that of other known baculoviruses. RT-PCR results revealed that...

journal_title：Virus genes

authors： Li Z,Pan L,Yu H,Li S,Zhang G,Pang Y

更新日期：2006-02-01 00:00:00

abstract：:Mokola virus, one of the six genotypes within the Lyssavirus genus of the Rhabdoviridae family, is believed to be exclusive to the African continent, where infections in various mammal species have been reported. After an isolation of Mokola virus at Umhlanga on the east coast of South Africa in 1970, the virus was no...

journal_title：Virus genes

authors： Nel L,Jacobs J,Jaftha J,von Teichman B,Bingham J,Olivier M

更新日期：2000-01-01 00:00:00

abstract：:The authentic major capsid protein 1 (VP1) of hamster polyomavirus (HaPyV) consists of 384 amino acid (aa) residues (42 kDa). Expression from an additional in-frame initiation codon located upstream from the authentic VP1 open reading frame (at position -4) might result in the synthesis of a 388 aa-long, amino-termina...

journal_title：Virus genes

authors： Voronkova T,Kazaks A,Ose V,Ozel M,Scherneck S,Pumpens P,Ulrich R

更新日期：2007-06-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) reactivates from a small fraction of latently infected neurons in vivo and neuronally differentiated (ND), quiescently infected (QIF)-PC12 cells in vitro. This may be the result of reactivation initiating in only a few cells, or reactivation followed by premature termination of the ...

journal_title：Virus genes

authors： Danaher RJ,Jacob RJ,Miller CS

更新日期：2006-10-01 00:00:00

abstract：:DNA fragments containing the secretory glycoprotein A (gA) gene of Marek's disease virus type 1 (MDV1) were cloned from the DNA libraries of very virulent Md5 and virulent BC-1 strains and sequenced. Two open reading frames (ORF1 and ORF2) were identified for both strains. The ORF1 has the potential to code for a prot...

journal_title：Virus genes

authors： Ihara T,Kato A,Ueda S,Ishihama A,Hirai K

更新日期：1989-11-01 00:00:00

abstract：:Emerging pseudorabies virus (PRV) variant has led to frequent outbreaks of PRV infection among Bartha-K61-vaccinated swine population in Chinese swine farms and caused high mortality in pigs of all age since late 2011. Here, we generated a gE/gI-deleted PRV (rPRVXJ-delgI/gE-EGFP) based on PRV variant strain (PRV-XJ) t...

journal_title：Virus genes

authors： Yin Y,Xu Z,Liu X,Li P,Yang F,Zhao J,Fan Y,Sun X,Zhu L

更新日期：2017-08-01 00:00:00

abstract：:Ramu stunt disease of sugarcane was first reported in Papua New Guinea in the mid 1980s. The disease can reduce sugarcane yields significantly and causes severe stunting and mortality in highly susceptible cultivars. The causal agent of Ramu stunt has been investigated but its characterization has not been completed. ...

journal_title：Virus genes

authors： Mollov D,Maroon-Lango C,Kuniata L

更新日期：2016-02-01 00:00:00

abstract：:Canine distemper virus (CDV) causes a highly contagious disease in a wide range of carnivores. The hemagglutinin (H) protein of viruses shows the highest variability and plays an important role in modulation of viral antigenicity, virulence, and receptor recognition. Since 2012, canine distemper (CD) outbreaks in fur-...

journal_title：Virus genes

authors： Tao R,Ba H,Chen J,Liu M,Pan H,Li X,Wang Q,Zhao J

更新日期：2020-02-01 00:00:00

abstract：:We have extended our studies using the mouse lymphoid cell system to determine if polyomavirus (Py) cell type specificity is a consequence of the simple presence of either the A and B enhancers, or if specificity results from specific combinations or arrangements of the individual enhancer elements. Mouse fibroblasts ...

journal_title：Virus genes

authors： Campbell BA,Villarreal LP

更新日期：1987-11-01 00:00:00

abstract：:In this study, the relative synonymous codon usage (RSCU) values, effective number of codon (ENC) values, nucleotide contents, and dinucleotide were used to investigate codon usage pattern of each protein-coding gene and genome among 31 Newcastle disease virus (NDV) isolates. The result shows that the overall extent o...

journal_title：Virus genes

authors： Wang M,Liu YS,Zhou JH,Chen HT,Ma LN,Ding YZ,Liu WQ,Gu YX,Zhang J

更新日期：2011-04-01 00:00:00

abstract：:The Tahyna virus (TAHV) is an important human pathogen in the Bunyaviridae family. To date, only the S and M segments of this virus have been sequenced, but the sequence of the L segment hasn't been established yet. In this study, we sequenced 963 nucleotides of the L segment of TAHV, comprising pre-motif A and motif ...

journal_title：Virus genes

authors： Quinan BR,de Brito Magalhães CL,Novaes RF,Dos Santos JR,Kroon EG,Bonjardim CA,Ferreira PC

更新日期：2008-06-01 00:00:00

abstract：:Macropodid herpesvirus 1 (MaHV-1) is an unclassified alphaherpesvirus linked with the fatal infections of kangaroos and other marsupials. During the characterisation of the internal repeat region of MaHV-1, an open reading frame (ORF) encoding for thymidylate synthase (TS) gene was identified and completely sequenced....

journal_title：Virus genes

authors： Guliani S,Polkinghorne I,Smith GA,Young P,Mattick JS,Mahony TJ

更新日期：2002-06-01 00:00:00

abstract：:Watermelon mosaic virus (WMV) is one of the most important viruses that causes different symptoms in Cucurbitaceae. WMV is a potyvirus with a worldwide distribution, but occurs most commonly in temperate and Mediterranean regions. Cucurbit species grown in Yazd, Esfahan, West Azerbaijan, Hormozgan, and Kerman province...

journal_title：Virus genes

authors： Sharifi M,Massumi H,Heydarnejad J,Hosseini Pour A,Shaabanian M,Rahimian H

更新日期：2008-12-01 00:00:00

abstract：:Newcastle disease viruses (NDV) isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) are mostly of mesogenic pathotype and characterized by a polybasic amino acid sequence motif at the fusion protein (F) cleavage site. This feature also applies to isolate R75/98 from Germany. Its genome consists of 15,192 nucle...

journal_title：Virus genes

authors： Heiden S,Grund C,Höper D,Mettenleiter TC,Römer-Oberdörfer A

更新日期：2014-12-01 00:00:00

abstract：:The complete genome sequence of the KGH strain of the first human rabies virus, which was isolated from a skin biopsy of a patient with rabies, whose symptoms developed due to bites from a raccoon dog in 2001. The size of the KGH strain genome was determined to be 11,928 nucleotides (nt) with a leader sequence of 58 n...

journal_title：Virus genes

authors： Park JS,Kim CK,Kim SY,Ju YR

更新日期：2013-04-01 00:00:00

abstract：:The complete nucleotide sequences of neuraminidase (NA) of two swine influenza viruses (H1N1) are presented. A/Sw/Quebec/5393/91 (SwQc91) virus, associated with the chronic respiratory disease and A/Sw/ Quebec/192/81 (SwQc81) virus, associated with the acute respiratory disease, were used. The deduced amino acid seque...

journal_title：Virus genes

authors： Arora DS,Tijssen P,Dea S,Henrichon M

更新日期：1997-01-01 00:00:00

abstract：:The complete genomic sequences of 13 PCV2 viruses obtained between 2005 and 2007 were analyzed in order to determine their phylogenetic relationship and identify possible recombination events between PCV2a and PCV2b. Twelve PCV2b viruses and one PCV2a virus were identified by phylogenetic analysis. Notably, two PCV2b ...

journal_title：Virus genes

authors： Kim HK,Luo Y,Moon HJ,Park SJ,Keum HO,Rho S,Park BK

更新日期：2009-12-01 00:00:00

abstract：:The foot-and-mouth disease virus (FMDV) nonstructural protein 3A plays an important role in viral replication, virulence, and host range. It has been shown that deletions of 10 or 19-20 amino acids in the C-terminal half of 3A attenuate serotype O and C FMDVs, which replicate poorly in bovine cells but normally in por...

journal_title：Virus genes

authors： Yuan T,Wang H,Li C,Yang D,Zhou G,Yu L

更新日期：2017-12-01 00:00:00

abstract：:Orf virus (ORFV), a typical member of the Parapoxvirus genus within the family Poxviridae, which is the causative agent of Orf, a common epitheliotropic viral disease of sheep, goats, wild ruminants, and humans. In the present study, we sequenced the complete genomic sequences of two ORFV strains (ORFV-SY17, isolated ...

journal_title：Virus genes

authors： Zhong J,Guan J,Zhou Y,Cui S,Wang Z,Zhou S,Xu M,Wei X,Gao Y,Zhai S,Song D,He W,Gao F,Zhao K

更新日期：2019-08-01 00:00:00

abstract：:Protein 2A is a non-structural protein of coxsackievirus B3 (CVB3), an important human pathogen that can cause a variety of human diseases. Protein 2A not only participates in viral life cycle, but also regulates host cell functions; however, the underlying mechanisms remain poorly understood. In order to better under...

journal_title：Virus genes

authors： Zhao T,Huang X,Xia Y

更新日期：2016-04-01 00:00:00

abstract：:Cap-independent translations of viral RNAs of enteroviruses and rhinoviruses, cardioviruses and aphthoviruses, hepatitis A and C viruses (HAV and HCV), and pestivirus are initiated by the direct binding of 40S ribosomal subunits to a cis-acting genetic element termed the internal ribosome entry site (IRES) or ribosome...

journal_title：Virus genes

authors： Le SY,Siddiqui A,Maizel JV Jr

更新日期：1996-01-01 00:00:00

abstract：:The complete genomic sequence of a sheep lentivirus isolate that presents a slow/low phenotype in vitro has been determined. The virus, designated P1OLV, was isolated from lung cells of a naturally infected sheep in Portugal. Three overlapping DNA fragments amplified by PCR, and encompassing the entire viral genome we...

journal_title：Virus genes

authors： Barros SC,Ramos F,Duarte M,Fagulha T,Cruz B,Fevereiro M

更新日期：2004-10-01 00:00:00

abstract：:A 13 amino acid residue insertion was found in the N-terminal region of the coat protein of several Maize dwarf mosaic virus isolates (MDMV). These insertions seem to be the result of a direct duplication event, but differ in some positions. In order to evaluate the influence of the insertion on the RNA secondary stru...

journal_title：Virus genes

authors： Petrik K,Sebestyén E,Gell G,Balázs E

更新日期：2010-02-01 00:00:00

abstract：:Marek's disease (MD), a lymphoproliferative disease of chicken is caused by a highly cell-associated alpha-herpesvirus, Marek's disease virus (MDV). MDV replicates in chicken lymphocytes and establishes a latent infection within CD4(+) T cells. The expression analysis of limited viral transcripts have revealed differe...

journal_title：Virus genes

authors： Heidari M,Huebner M,Kireev D,Silva RF

更新日期：2008-04-01 00:00:00

abstract：:The nucleotide sequence of the 3' terminal region of potato virus Y (PVY) was determined. Starting with a poly(A) tail of 18 residues a non-coding region of 335 nucleotides precedes the region encoding for the virus coat protein (cp) 801 nucleotides long ending with a TGA. This region was located by comparing the pred...

journal_title：Virus genes

authors： Rosner A,Raccah B

更新日期：1988-06-01 00:00:00

abstract：:Hepatitis E virus (HEV) has emerged as an important cause of epidemic and sporadic acute viral hepatitis worldwide, which is a major public health challenge. A better understanding of the interaction between the virus and the host cell would be very helpful for its therapy. Swine HEV (SHEV) open reading frame 3 (ORF3)...

journal_title：Virus genes

authors： Cheng Y,Du L,Shi Q,Jiao H,Zhang X,Hao Y,Rong H,Zhang J,Jia X,Guo S,Kuang W,Zhang H,Chen C,Wang F

更新日期：2013-08-01 00:00:00

abstract：:We amplified the capsid protein gene fragments of 30 Japanese isolates of feline calicivirus (FCV), including the C, D, and E regions, by reverse transcription-polymerase chain reaction (RT-PCR), followed by direct sequencing. Alignment of the predicted amino acid sequences, together with other published sequences fro...

journal_title：Virus genes

authors： Horimoto T,Takeda Y,Iwatsuki-Horimoto K,Sugii S,Tajima T

更新日期：2001-01-01 00:00:00

abstract：:Jaagsiekte sheep retrovirus (JSRV) is the causative agent of ovine pulmonary adenocarcinoma (OPA), a contagious lung cancer in sheep. Previous studies have shown that the JSRV envelope protein (Env) functions as an oncogene, in that it can morphologically transform rodent fibroblast and epithelial cell lines. To obtai...

journal_title：Virus genes

authors： Dakessian RM,Inoshima Y,Fan H

更新日期：2007-08-01 00:00:00