Abstract:
:Mokola virus, one of the six genotypes within the Lyssavirus genus of the Rhabdoviridae family, is believed to be exclusive to the African continent, where infections in various mammal species have been reported. After an isolation of Mokola virus at Umhlanga on the east coast of South Africa in 1970, the virus was not reported in South Africa until its reappearance in 1995. Since then a total of six new isolates of the virus were made, three from the East London region in 1995 and 1996, two near Pinetown in 1997 and a further isolate in a residential suburb of the city of Pietermaritzburg, in 1998. These isolation sites are respectively about 500 km (East London region) and 23 to 60 km from the site of the 1970 isolation Phylogenetically the three isolates from the East London area were similar and could be distinguished from the four KwaZulu-Natal isolates, which formed a defined group of their own. The viruses comprising these two clusters were also found to be distant from another southern African isolate, made in 1982 in Zimbabwe, Mokola virus isolates thus conforms to a pattern of virus evolution strongly influenced by geographical determinants. In comparison to Rabies virus, of which at least two different biotypes are known and a vast array of different wildlife species contribute to its complex epidemiology on the sub-continent, Mokola viruses have only been isolated form one species, i.e. domestic cats, in South Africa. Nevertheless, the heterogeneity among the Mokola virus isolates is far greater than the degree of variation among the Rabies virus populations of the region.
journal_name
Virus Genesjournal_title
Virus genesauthors
Nel L,Jacobs J,Jaftha J,von Teichman B,Bingham J,Olivier Mdoi
10.1023/a:1008120511752subject
Has Abstractpub_date
2000-01-01 00:00:00pages
103-6issue
2eissn
0920-8569issn
1572-994Xjournal_volume
20pub_type
杂志文章相关文献
VIRUS GENES文献大全abstract::Several important biological processes are performed by distinct functional domains found on replication-associated protein (Rep) encoded by AC1 of geminiviruses. Two truncated forms of replicase (tAC1) gene, capable of expressing only the N-terminal 669 bp (5'AC1) and C-terminal 783 bp (3'AC1) nucleotides cloned unde...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-011-0569-9
更新日期:2011-04-01 00:00:00
abstract::We report the detection of rabbit haemorrhagic disease virus 2 (RHDV2) in the Madeira archipelago, Portugal. Viral circulation was confirmed by RT-qPCR and vp60 sequencing. Epidemiological data revealed the outbreak initiated in October 2016 in Porto Santo affecting wild and domestic rabbits. It was then detected thre...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1483-6
更新日期:2017-12-01 00:00:00
abstract::The establishment of viral pathogens in new host environments following spillover events probably requires adaptive changes within both the new host and pathogen. After many generations, signals for ancient cross-species transmission may become lost and a strictly host-adapted phylogeny may mimic true co-divergence wh...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01702-x
更新日期:2019-12-01 00:00:00
abstract::Herpesvirus saimiri induces acute lymphomas and leukemias in primates and rabbits. Sequence divergence of the right end unique region of the genome classifies virus strains into three groups (A, B, and C), and previous studies have demonstrated correlation between DNA grouping and oncogenicity. In order to relate diff...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF01703599
更新日期:1994-01-01 00:00:00
abstract::The varicella zoster virus (VZV) ORF4 protein, one of immediate-early genes protein, is associated with the tegument in purified virions. ORF4 protein functions at both transcriptional and post-transcriptional levels, present during different phase of whole VZV life cycle. ORF4 protein acts as a nucleocytoplasm shuttl...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-013-1006-z
更新日期:2014-04-01 00:00:00
abstract::Dengue virus (DENV; Genus Flavivirus, Family Flaviviridae) has been circulating in Brazil since at least the mid-1980s and continues to be responsible for sporadic cases of Dengue fever and Dengue hemorrhagic fever throughout this country. Here, we describe the full genomes of two new Brazilian DENV-serotype 1 (DENV-1...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-009-0428-0
更新日期:2010-02-01 00:00:00
abstract::We have examined sequence variability among nine isolates of hop stunt viroid (HSVd) collected from hop gardens in Tohoku district in Japan, the only area in the world where hop stunt disease is endemic. Six different consensus and one-consensus sequences as well as 12 sequence variants were detected in the nine HSVd-...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1008182302704
更新日期:2001-01-01 00:00:00
abstract::The intraspecies variability of capsid proteins of five viruses of the genus Comovirus was established. Inclusion of both capsid proteins to the sequence analysis reduces some uncertainties about species/strains demarcation criteria in the Comovirus genus. New approach is proposed for discrimination of Turnip ringspot...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-009-0443-1
更新日期:2010-04-01 00:00:00
abstract::Partial genome segments of a begomovirus were previously amplified from Wissadula amplissima exhibiting yellow-mosaic and leaf-curl symptoms in the parish of St. Thomas, Jamaica and this isolate assigned to a tentative begomovirus species, Wissadula golden mosaic St. Thomas virus. To clone the complete genome of this ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-009-0401-y
更新日期:2009-12-01 00:00:00
abstract::We amplified the capsid protein gene fragments of 30 Japanese isolates of feline calicivirus (FCV), including the C, D, and E regions, by reverse transcription-polymerase chain reaction (RT-PCR), followed by direct sequencing. Alignment of the predicted amino acid sequences, together with other published sequences fro...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1011892120875
更新日期:2001-01-01 00:00:00
abstract::A H3N2 canine influenza virus, A/canine/Guangdong/3/2011 (H3N2), was isolated from roaming dogs in rural China. Sequence and phylogenetic analysis of eight gene segments revealed that the A/canine/Guangdong/3/2011 (H3N2) was most similar to a recent H3N2 canine influenza virus isolated in cats from South Korea, which ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-013-0882-6
更新日期:2013-06-01 00:00:00
abstract::We performed whole genome sequencing of 22 H9N2 avian influenza viruses (AIV) isolated from domestic laying hens on farms between 2005 and 2008, and compared the sequences with viruses previously reported in Asia. A previous study revealed that two antigenically distinct sublineages were established within the MS96 li...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-012-0737-6
更新日期:2012-08-01 00:00:00
abstract::By using a phage vector (lambda ZAP II) and the mRNA extracted from IMR-32 cells infected with the RC.HL strain of rabies virus, we constructed a cDNA library from which four nucleoprotein (N)-specific cDNA clones were obtained by Southern blot hybridization. These clones contained a cDNA insert of about 1.4 kb, in wh...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF01703607
更新日期:1994-03-01 00:00:00
abstract::Porcine reproductive and respiratory syndrome (PRRS) is a swine disease of major economic importance that causes reproductive and respiratory problems in pigs. In the present study, one strain of porcine reproductive and respiratory syndrome virus (PRRSV) was isolated in Xinjiang province, Northwest China, designated ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-014-1122-4
更新日期:2015-02-01 00:00:00
abstract::Geminiviridae consists of a large group of single-stranded DNA viruses that cause tremendous losses worldwide. Frequent mixed infection and high rates of recombination and mutation allow them to adapt rapidly to new hosts and overcome hosts' resistances. Therefore, an effective strategy able to confer plants with resi...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-014-1041-4
更新日期:2014-06-01 00:00:00
abstract::Fourteen infectious bronchitis viruses (IBVs) were isolated in Korea between 2001 and 2003 from chickens suspected to be infected with IBVs. The nucleocapsid (N) protein genes of the various IBVs were amplified by reverse transcriptase-polymerase chain reaction (RT-PCR) and were cloned and sequenced, and the nucleotid...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-005-1788-8
更新日期:2005-10-01 00:00:00
abstract::Papillomaviruses are small and complex viruses with circular DNA genome that belongs to the Papillomavirus family, which comprises at least 39 genera. The bovine papillomavirus (BPV) causes an infectious disease that is characterized by chronic and proliferative benign tumors that affect cattle worldwide. In the prese...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1406-y
更新日期:2017-02-01 00:00:00
abstract::Molecular characterization of Bovine leukemia virus (BLV) isolates from Brazil using the env gene sequences revealed a high conservation of this gene. In most cases the substitutions corresponded to silent transitions. In addition, cystein residues, potential glycosylation sites, neutralization domains and other criti...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-006-0011-x
更新日期:2007-06-01 00:00:00
abstract::Sacbrood virus (SBV) represents a serious threat to the health of managed honeybees. We determined four complete SBV genomic sequences (AmSBV-Kor1, AmSBV-Kor2, AcSBV-Kor3, and AcSBV-Kor4) isolated from Apis mellifera and Apis cerana in various regions of South Korea. A phylogenetic tree was constructed from the comple...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-015-1268-8
更新日期:2016-04-01 00:00:00
abstract::The Kansas/15626/84 (Ka) and Shipping Fever (SF) strains of bovine parainfluenza virus type 3 (BPIV3) replicate less efficiently than human PIV3 (HPIV3) in the upper and lower respiratory tract of rhesus monkeys, and BPIV3 Ka is also highly attenuated in humans and is in clinical trials as a candidate vaccine against ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1008130917204
更新日期:2000-01-01 00:00:00
abstract::Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer associated with the Merkel cell polyomavirus (MCPyV). The MCPyV genome, which is clonally integrated in the majority of MCCs, encodes the regulatory small T (sT) antigen. Previously, reports have established MCPyV sT antigen as a potent onco...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1304-3
更新日期:2016-06-01 00:00:00
abstract::Caliciviruses are nonenveloped with a polyadenylated genome of approximately 7.6 kb and a single capsid protein. The "RNA Fold" computer program was used to analyze 3'-terminal noncoding sequences of five feline calicivirus (FCV), rabbit hemorrhagic disease virus (RHDV), and two San Miguel sea lion virus (SMSV) isolat...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF01704518
更新日期:1994-07-01 00:00:00
abstract::African monkeys are resistant to HIV-1 infection due to intrinsic restriction mechanisms found in their cells. However, although they can be infected by monkey-adapted modified HIV-1 particles that are designed to overcome known restriction factors, virus numbers drop to undetectable levels in immunocompetent animals....
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01731-x
更新日期:2020-04-01 00:00:00
abstract::Protein 2A is a non-structural protein of coxsackievirus B3 (CVB3), an important human pathogen that can cause a variety of human diseases. Protein 2A not only participates in viral life cycle, but also regulates host cell functions; however, the underlying mechanisms remain poorly understood. In order to better under...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-015-1270-1
更新日期:2016-04-01 00:00:00
abstract::Porcine pegiviruses (PPgV) have been first discovered in serum samples from domestic pigs in Germany in 2016 and then in the USA in 2018. To date, there is no documentation with respect to the presence of PPgVs in domestic pigs in China. Herein, we attempted to determine the presence and prevalence of PPgV in China an...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-018-1624-6
更新日期:2019-04-01 00:00:00
abstract::The VP2 gene DNA (1.4 kb in approximate) of a very virulent infectious bursal disease virus (vvIBDV) Chinju strain detected in Chinju, Korea was cloned into the bacmid, a baculovirus shuttle vector, through transposition of the gene from initially cloned pFastBacHTa plasmid, a baculovirus expression vector, and was su...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1025128619976
更新日期:2003-08-01 00:00:00
abstract::Foot-and-mouth disease (FMD) is the most contagious and devastating disease of livestock. Our previous studies demonstrated that TK(-)/gG(-)/P1(+), a recombinant expressing the FMDV capsid precursor protein (P1) based on attenuated pseudorabies virus (PRV) TK(-)/gG(-), could be used as a recombinant vaccine to protect...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-008-0204-6
更新日期:2008-04-01 00:00:00
abstract::A maximum clade credibility tree constructed using the full-length spike (S) and hemagglutinin-esterase genes revealed that Vietnamese Bovine coronavirus (BCoV) strains belong to a single cluster (C1); therefore, they might share a common origin with Cuban and Chinese BCoV strains. The omega values of cluster 1 (C1) a...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01647-1
更新日期:2019-06-01 00:00:00
abstract::Emerging pseudorabies virus (PRV) variant has led to frequent outbreaks of PRV infection among Bartha-K61-vaccinated swine population in Chinese swine farms and caused high mortality in pigs of all age since late 2011. Here, we generated a gE/gI-deleted PRV (rPRVXJ-delgI/gE-EGFP) based on PRV variant strain (PRV-XJ) t...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1454-y
更新日期:2017-08-01 00:00:00
abstract::White spot syndrome virus (WSSV) is one of the most virulent pathogens causing high mortality in shrimp. The viral early genes play a key role in DNA replication and virus proliferation. In this study, a WSSV gene (wsv477) encoding 208 amino acid peptides was characterized as an early gene. The temporal analysis showe...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-006-0053-0
更新日期:2007-04-01 00:00:00