Abstract:
:A 13 amino acid residue insertion was found in the N-terminal region of the coat protein of several Maize dwarf mosaic virus isolates (MDMV). These insertions seem to be the result of a direct duplication event, but differ in some positions. In order to evaluate the influence of the insertion on the RNA secondary structure and stability, the RNA secondary structures and minimum free energies (MFE) of all existing MDMV coat protein sequences were estimated using three different softwares, the Vienna RNA Package, NUPACK, and UNAFold, and compared to the secondary structure and MFE of various random sequence collections preserving the nucleotide distribution of MDMV. The bioinformatic analysis showed that the insertion stabilizes the RNA structure of the coat protein gene.
journal_name
Virus Genesjournal_title
Virus genesauthors
Petrik K,Sebestyén E,Gell G,Balázs Edoi
10.1007/s11262-009-0425-3subject
Has Abstractpub_date
2010-02-01 00:00:00pages
135-9issue
1eissn
0920-8569issn
1572-994Xjournal_volume
40pub_type
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