The complete nucleotide sequence and genome organization of Fig cryptic virus, a novel bipartite dsRNA virus infecting fig, widely distributed in the Mediterranean basin.


:Two double-stranded RNA (dsRNA) segments of a virus with a bipartite genome identified in fig (Ficus carica L.) and denoted Fig cryptic virus (FCV) were cloned and sequenced. Viral dsRNAs are 1696 bp (RNA-1) and 1415 bp (RNA-2) in size. RNA-1 contains a single ORF (1419 nt) potentially encoding a 54 kDa protein and comprising the conserved amino acid motifs of the RNA-dependent RNA polymerase (RdRp) domain of species of the genus Alphacryptovirus. Its full-length amino acid sequence has the highest identity with Raphanus sativus cryptic virus 2 (RsCV-2) (36%), Beet cryptic virus 3 (BCV-3) (36%) and Fragaria chiloensis cryptic virus (FCCV) (34%). RNA-2 has also a single ORF (1014 nt) coding for a polypeptide with a predicted molecular mass of 38 kDa, identified as the viral coat protein (CP). In a phylogenetic tree constructed with the amino acid sequences of the RdRp domain, FCV clusters in a clade comprising BCV-3 and a number of tentative species of the genus Alphacryptovirus. FCV is not mechanically transmissible. It was detected in fig orchards of six Mediterranean countries (Albania, Algeria, Italy, Lebanon, Syria and Tunisia) where it does not seem to induce a visible disease.


Virus Genes


Virus genes


Elbeaino T,Kubaa RA,Digiaro M,Minafra A,Martelli GP




Has Abstract


2011-06-01 00:00:00












  • Molecular analysis of the complete genomic sequences of four isolates of Gooseberry vein banding associated virus.

    abstract::The presence of Gooseberry vein banding associated virus (GVBaV), a badnavirus in the family Caulimoviridae, is strongly correlated with gooseberry vein banding disease in Ribes spp. In this study, full-length genomic sequences of four GVBaV isolates from different hosts and geographic regions were determined to be 76...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Xu D,Mock R,Kinard G,Li R

    更新日期:2011-08-01 00:00:00

  • Complete genome sequence of a novel Plum pox virus strain W isolate determined by 454 pyrosequencing.

    abstract::The near-complete (99.7 %) genome sequence of a novel Russian Plum pox virus (PPV) isolate Pk, belonging to the strain Winona (W), has been determined by 454 pyrosequencing with the exception of the thirty-one 5'-terminal nucleotides. This region was amplified using 5'RACE kit and sequenced by the Sanger method. Genom...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Sheveleva A,Kudryavtseva A,Speranskaya A,Belenikin M,Melnikova N,Chirkov S

    更新日期:2013-10-01 00:00:00

  • High prevalence of adeno-associated virus (AAV) type 2 rep DNA in cervical materials: AAV may be sexually transmitted.

    abstract::Adeno-associated virus (AAV) is a human parvovirus that in laboratory and animal models has the ability to suppress the oncogenic phenotype of a variety of viruses and cellular derived oncogenes. The inhibitory effects of AAV have been mapped to its rap gene (Rep78 protein). Furthermore, seroepidemiologic data indicat...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Han L,Parmley TH,Keith S,Kozlowski KJ,Smith LJ,Hermonat PL

    更新日期:1996-01-01 00:00:00

  • Comparative analysis of American Dengue virus type 1 full-genome sequences.

    abstract::Dengue virus (DENV; Genus Flavivirus, Family Flaviviridae) has been circulating in Brazil since at least the mid-1980s and continues to be responsible for sporadic cases of Dengue fever and Dengue hemorrhagic fever throughout this country. Here, we describe the full genomes of two new Brazilian DENV-serotype 1 (DENV-1...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Carvalho SE,Martin DP,Oliveira LM,Ribeiro BM,Nagata T

    更新日期:2010-02-01 00:00:00

  • Phylogenetic analysis of partial RNA-polymerase blocks II and III of Rabies virus isolated from the main rabies reservoirs in Brazil.

    abstract::This study describes the results of the sequencing and analysis of segments of Blocks II and III of the RNA polymerase L gene of Rabies virus isolates from different reservoir species of Brazil. The phylogenetic relations of the virus were determined and a variety of species-specific nucleotides were found in the anal...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Carnieli P Jr,de Novaes Oliveira R,de Oliveira Fahl W,de Carvalho Ruthner Batista HB,Scheffer KC,Iamamoto K,Castilho JG

    更新日期:2012-08-01 00:00:00

  • The 2A2 protein of Duck hepatitis A virus type 1 induces apoptosis in primary cell culture.

    abstract::Duck hepatitis A virus type 1, (DHAV-1) 2A2pro, is one of the most highly conserved viral proteins within the DHAV serotypes. However, its effect on host cells is unclear. We predicted that DHAV-1 2A2pro was a GTPase-like protein based on the results of multiple sequence alignment and homologous modeling analysis. Upo...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Cao J,Ou X,Zhu D,Ma G,Cheng A,Wang M,Chen S,Jia R,Liu M,Sun K,Yang Q,Wu Y,Chen X

    更新日期:2016-12-01 00:00:00

  • Complete genome analysis of two new bacteriophages isolated from impetigo strains of Staphylococcus aureus.

    abstract::Exfoliative toxin A (ETA)-coding temperate bacteriophages are leading contributors to the toxic phenotype of impetigo strains of Staphylococcus aureus. Two distinct eta gene-positive bacteriophages isolated from S. aureus strains which recently caused massive outbreaks of pemphigus neonatorum in Czech maternity hospit...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Botka T,Růžičková V,Konečná H,Pantůček R,Rychlík I,Zdráhal Z,Petráš P,Doškař J

    更新日期:2015-08-01 00:00:00

  • Sequencing, phylogenetic analysis, and potential recombination events of infectious bronchitis viruses isolated in Korea.

    abstract::The S2 glycoprotein and membrane (M) protein genes and S1 glycoprotein and nucleocapsid (N) genes of 11 Korean infectious bronchitis virus (IBV) isolates were amplified by RT-PCR, cloned, and sequenced. The resultant nucleotide sequences were compared with the published sequences for non-Korean IBV strains. Korean IBV...

    journal_title:Virus genes

    pub_type: 信件


    authors: Song JE,Jeong WG,Sung HW,Kwon HM

    更新日期:2013-04-01 00:00:00

  • Nucleotide sequence analysis of rotavirus gene 11 from two tissue culture-adapted ATCC strains, RRV and Wa.

    abstract::We report here nucleotide sequence and characterization of gene 11 from two tissue culture-adapted ATCC rhesus (RRV) and human (Wa) strains of rotavirus. Gene 11 sequence encodes a nonstructural protein, NSP5 and also encodes NSP6, from an out of phase open reading frame. Sequence of RRV(ATCC) gene 11 represents the f...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Mohan KV,Atreya CD

    更新日期:2001-12-01 00:00:00

  • Insights into Jumonji C-domain containing protein 6 (JMJD6): a multifactorial role in foot-and-mouth disease virus replication in cells.

    abstract::The Jumonji C-domain containing protein 6 (JMJD6) has had a convoluted history, and recent reports indicating a multifactorial role in foot-and-mouth disease virus (FMDV) infection have further complicated the functionality of this protein. It was first identified as the phosphatidylserine receptor on the cell surface...

    journal_title:Virus genes

    pub_type: 杂志文章,评审


    authors: Lawrence P,Rieder E

    更新日期:2017-06-01 00:00:00

  • Complete genome sequences of three rabies viruses isolated from rabid raccoon dogs and a cow in Korea.

    abstract::The complete genomes of three rabies viruses (BD0406CC, BV9901PJ, and 08F40) of two raccoon dogs (Nyctereutes procyonoides koreensis) and a cow were determined. The genomic organization is typical of rabies viruses, and the open reading frames of the N, P, M, G, and L genes are 1,353, 894, 609, 1,575, and 6,384 bases ...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Oem JK,Kim SH,Kim YH,Lee MH,Lee KK

    更新日期:2013-12-01 00:00:00

  • Molecular characterization of the env gene from Brazilian field isolates of Bovine leukemia virus.

    abstract::Molecular characterization of Bovine leukemia virus (BLV) isolates from Brazil using the env gene sequences revealed a high conservation of this gene. In most cases the substitutions corresponded to silent transitions. In addition, cystein residues, potential glycosylation sites, neutralization domains and other criti...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Camargos MF,Pereda A,Stancek D,Rocha MA,dos Reis JK,Greiser-Wilke I,Leite RC

    更新日期:2007-06-01 00:00:00

  • Characterization of a bovine viral diarrhea virus originated from cattle in Gansu Province, China.

    abstract::A bovine viral diarrhea disease virus (BVDV) GS-4 was isolated in Western China form dairy cattle with respiratory disease. Genomic comparison analysis with the 5' half genome sequence encompassing the coding region of N(pro), capsid, and envelope glycoproteins showed that the GS-4 should be classified into BVDV-1b1, ...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Gao S,Shao J,Du J,Lin T,Cong G,Zhao F,Chang H,Yin H

    更新日期:2013-08-01 00:00:00

  • Identification of a thymidylate synthase gene within the genome of Chilo iridescent virus.

    abstract::The thymidylate synthase (TS, EC is essential for the de novo synthesis of dTMP in pro- and eucaryotic organisms. Consequently it plays a major role in the replication of the DNA genome of a cell or a DNA virus. The gene encoding the TS of Chilo iridescent virus (CIV) was identified by nucleotide sequence an...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Müller K,Tidona CA,Bahr U,Darai G

    更新日期:1998-01-01 00:00:00

  • Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.

    abstract::Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicist...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Phan TG,Del Valle Mendoza J,Sadeghi M,Altan E,Deng X,Delwart E

    更新日期:2018-02-01 00:00:00

  • Barriers to systemic application of virus-based vectors in gene therapy: lessons from adenovirus type 5.

    abstract::Currently, virus-based vectors, namely derivatives of the adenovirus, are frequently used in a wide variety of ex vivo or local gene therapeutic applications. However, the efficacy of virus-based vectors in systemic applications is presently still extremely limited. Complex interactions of the various vector types wit...

    journal_title:Virus genes

    pub_type: 杂志文章,评审


    authors: Jönsson F,Kreppel F

    更新日期:2017-10-01 00:00:00

  • Molecular characterization of KGH, the first human isolate of rabies virus in Korea.

    abstract::The complete genome sequence of the KGH strain of the first human rabies virus, which was isolated from a skin biopsy of a patient with rabies, whose symptoms developed due to bites from a raccoon dog in 2001. The size of the KGH strain genome was determined to be 11,928 nucleotides (nt) with a leader sequence of 58 n...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Park JS,Kim CK,Kim SY,Ju YR

    更新日期:2013-04-01 00:00:00

  • Phylodynamic analysis of two amino acid substitutions in the hemagglutinin protein of canine distemper virus strains detected in fur-bearing animals in China.

    abstract::Canine distemper virus (CDV) causes a highly contagious disease in a wide range of carnivores. The hemagglutinin (H) protein of viruses shows the highest variability and plays an important role in modulation of viral antigenicity, virulence, and receptor recognition. Since 2012, canine distemper (CD) outbreaks in fur-...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Tao R,Ba H,Chen J,Liu M,Pan H,Li X,Wang Q,Zhao J

    更新日期:2020-02-01 00:00:00

  • A local strain of Paprika mild mottle virus breaks L3 resistance in peppers and is accelerated in Tomato brown rugose fruit virus-infected Tm-22-resistant tomatoes.

    abstract::During October 2014, unfamiliar mild mosaic and mottling symptoms were identified on leaves of pepper (Capsicum chinense cv. Habanero) seedlings grown in the Arava valley in Israel 2-3 weeks post planting. Symptomatic plants were tested positive by ELISA using laboratory-produced antisera for tobamovirus species. Typi...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Luria N,Smith E,Sela N,Lachman O,Bekelman I,Koren A,Dombrovsky A

    更新日期:2018-04-01 00:00:00

  • Evolution of feline immunodeficiency virus Gag proteins.

    abstract::We evaluated the predicted biochemical properties of Gag proteins from a diverse group of feline immunodeficiency viruses (FIV) to determine how different evolutionary histories of virus and host have changed or constrained these important structural proteins. Our data are based on FIV sequences derived from domestic ...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Burkala E,Poss M

    更新日期:2007-10-01 00:00:00

  • Prevalence and genotyping of group 3 torque teno viruses detected in health care workers in Hungary.

    abstract::Torque teno viruses (TTVs) are classified into the Anellovirus genus of the Circoviridae family. In addition to TTV isolates, TTV genogroup 3 also includes the 8 virus strains known as SENV-A to H. In this study, the prevalence of TTV group 3 viruses and that of SENV-D and H in particular were determined among the sta...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Dencs A,Hettmann A,Szomor KN,Kis Z,Takács M

    更新日期:2009-08-01 00:00:00

  • Identification of a new Bombyx mori nucleopolyhedrovirus and analysis of its bro gene family.

    abstract::The highly pathogenic Bombyx mori nucleopolyhedrovirus (BmNPV) has caused severe damages to sericulture in many countries, and the relationship between the pathogenicity of various BmNPV strains and their geographical evolution has been the topic of our interest. In this study, we isolated a new BmNPV strain from Thai...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Zhou JB,Li XQ,De-Eknamkul W,Suraporn S,Xu JP

    更新日期:2012-06-01 00:00:00

  • Capsid protein gene variation among feline calicivirus isolates.

    abstract::We amplified the capsid protein gene fragments of 30 Japanese isolates of feline calicivirus (FCV), including the C, D, and E regions, by reverse transcription-polymerase chain reaction (RT-PCR), followed by direct sequencing. Alignment of the predicted amino acid sequences, together with other published sequences fro...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Horimoto T,Takeda Y,Iwatsuki-Horimoto K,Sugii S,Tajima T

    更新日期:2001-01-01 00:00:00

  • The N-terminus of vaccinia virus host range protein C7L is essential for function.

    abstract::Vaccinia virus (VACV), a member of the Poxviridae family of large double-stranded DNA viruses, is being used as a smallpox vaccine as well as an expression vector for immunization against other infectious diseases and cancer. The host range of wild type VACV is very broad among mammalian cells. C7L is a host range gen...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Terajima M,Urban SL,Leporati AM

    更新日期:2013-02-01 00:00:00

  • A common structural core in the internal ribosome entry sites of picornavirus, hepatitis C virus, and pestivirus.

    abstract::Cap-independent translations of viral RNAs of enteroviruses and rhinoviruses, cardioviruses and aphthoviruses, hepatitis A and C viruses (HAV and HCV), and pestivirus are initiated by the direct binding of 40S ribosomal subunits to a cis-acting genetic element termed the internal ribosome entry site (IRES) or ribosome...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Le SY,Siddiqui A,Maizel JV Jr

    更新日期:1996-01-01 00:00:00

  • Genetic diversity of Apodemus agrarius-borne hantaan virus in Korea.

    abstract::Hantaan (HTN) virus, the etiologic agent of clinically severe hemorrhagic fever with renal syndrome (HFRS), was first isolated in 1976 from lung tissues of striped field mice (Apodemus agrarius) captured in Songnae-ri, Kyungki-do, Korea. To clarify the genetic diversity and phylogenetic relationship among Korean strai...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Song JW,Baek LJ,Kim SH,Kho EY,Kim JH,Yanagihara R,Song KJ

    更新日期:2000-10-01 00:00:00

  • A synthetic peptide derived from domain III envelope glycoprotein of Dengue virus induces neutralizing antibody.

    abstract::Dengue virus (DENV) is an arthropod-borne human pathogen that represents a severe public health threat in both endemic and non-endemic regions. So far, there is no licensed vaccine or specific drugs available for dengue fever. A fifteen-amino-acid-long peptide that includes the NGR motif was chemically synthesized and...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Mary JA,Jittmittraphap A,Chattanadee S,Leaungwutiwong P,Shenbagarathai R

    更新日期:2018-02-01 00:00:00

  • A live gI/gE-deleted pseudorabies virus (PRV) protects weaned piglets against lethal variant PRV challenge.

    abstract::Emerging pseudorabies virus (PRV) variant has led to frequent outbreaks of PRV infection among Bartha-K61-vaccinated swine population in Chinese swine farms and caused high mortality in pigs of all age since late 2011. Here, we generated a gE/gI-deleted PRV (rPRVXJ-delgI/gE-EGFP) based on PRV variant strain (PRV-XJ) t...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Yin Y,Xu Z,Liu X,Li P,Yang F,Zhao J,Fan Y,Sun X,Zhu L

    更新日期:2017-08-01 00:00:00

  • The PDZ domain binding motif (PBM) of human T-cell leukemia virus type 1 Tax can be substituted by heterologous PBMs from viral oncoproteins during T-cell transformation.

    abstract::Several tumor viruses, such as human T-cell leukemia virus (HTLV), human papilloma virus (HPV), human adenovirus, have high-oncogenic and low-oncogenic subtypes, and such subtype-specific oncogenesis is associated with the PDZ-domain binding motif (PBM) in their transforming proteins. HTLV-1, the causative agent of ad...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Aoyagi T,Takahashi M,Higuchi M,Oie M,Tanaka Y,Kiyono T,Aoyagi Y,Fujii M

    更新日期:2010-04-01 00:00:00

  • Simultaneous analysis of the bidirectional African cassava mosaic virus promoter activity using two different luciferase genes.

    abstract::The expression of geminivirus genes is controlled by bidirectional promoters which are located in the large intergenic region of the circular DNA genomes and specifically regulated by virus encoded proteins. In order to study the simultaneous regulation of both orientations of the DNA A and DNA B promoters of African ...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Frey PM,Schärer-Hernández NG,Fütterer J,Potrykus I,Puonti-Kaerlas J

    更新日期:2001-03-01 00:00:00