The complete nucleotide sequence and genome organization of Fig cryptic virus, a novel bipartite dsRNA virus infecting fig, widely distributed in the Mediterranean basin.


:Two double-stranded RNA (dsRNA) segments of a virus with a bipartite genome identified in fig (Ficus carica L.) and denoted Fig cryptic virus (FCV) were cloned and sequenced. Viral dsRNAs are 1696 bp (RNA-1) and 1415 bp (RNA-2) in size. RNA-1 contains a single ORF (1419 nt) potentially encoding a 54 kDa protein and comprising the conserved amino acid motifs of the RNA-dependent RNA polymerase (RdRp) domain of species of the genus Alphacryptovirus. Its full-length amino acid sequence has the highest identity with Raphanus sativus cryptic virus 2 (RsCV-2) (36%), Beet cryptic virus 3 (BCV-3) (36%) and Fragaria chiloensis cryptic virus (FCCV) (34%). RNA-2 has also a single ORF (1014 nt) coding for a polypeptide with a predicted molecular mass of 38 kDa, identified as the viral coat protein (CP). In a phylogenetic tree constructed with the amino acid sequences of the RdRp domain, FCV clusters in a clade comprising BCV-3 and a number of tentative species of the genus Alphacryptovirus. FCV is not mechanically transmissible. It was detected in fig orchards of six Mediterranean countries (Albania, Algeria, Italy, Lebanon, Syria and Tunisia) where it does not seem to induce a visible disease.


Virus Genes


Virus genes


Elbeaino T,Kubaa RA,Digiaro M,Minafra A,Martelli GP




Has Abstract


2011-06-01 00:00:00












  • Phylogenetic analysis of hop and grapevine isolates of hop stunt viroid supports a grapevine origin for hop stunt disease.

    abstract::We have examined sequence variability among nine isolates of hop stunt viroid (HSVd) collected from hop gardens in Tohoku district in Japan, the only area in the world where hop stunt disease is endemic. Six different consensus and one-consensus sequences as well as 12 sequence variants were detected in the nine HSVd-...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Sano T,Mimura R,Ohshima K

    更新日期:2001-01-01 00:00:00

  • High prevalence of adeno-associated virus (AAV) type 2 rep DNA in cervical materials: AAV may be sexually transmitted.

    abstract::Adeno-associated virus (AAV) is a human parvovirus that in laboratory and animal models has the ability to suppress the oncogenic phenotype of a variety of viruses and cellular derived oncogenes. The inhibitory effects of AAV have been mapped to its rap gene (Rep78 protein). Furthermore, seroepidemiologic data indicat...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Han L,Parmley TH,Keith S,Kozlowski KJ,Smith LJ,Hermonat PL

    更新日期:1996-01-01 00:00:00

  • Nucleotide sequence of the genome segment encoding nonstructural protein NS1 of bluetongue virus serotype 20 from Australia.

    abstract::The nucleotide sequence of the genome segment (S6) encoding the nonstructural protein NS1 of an Australian isolate of bluetongue virus serotype 20 (BTV 20) has been determined from a series of overlapping cDNA clones synthesized using two terminal 15-mer oligonucleotides as primers. The gene consists of 1769 nucleotid...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Cowley JA

    更新日期:1992-11-01 00:00:00

  • Sequences of terminal non-coding regions from four dengue-2 viruses isolated from patients exhibiting different disease severities.

    abstract::We have determined the 5' and 3' non-coding regions (NCR) of four dengue-2 viruses isolated from dengue patients with different clinical severities in Nakhon Phanom, Northeastern Thailand in 1993. The results were compared to prototype dengue-2 strains and were found to have highest homology with the New Guinea C stra...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Mangada MN,Igarashi A

    更新日期:1997-01-01 00:00:00

  • Characterization of a J domain gene of Spodoptera litura multicapsid nucleopolyhedrovirus.

    abstract::Spodoptera litura multicapsid nucleopolyhedrovirus (SpltMNPV) ORF39 (designated as the bjdp gene) is the only J domain gene recorded in baculovirus genomes to date. Computer-assisted analysis revealed that its deduced amino acid sequences possessed a coiled-coil region and a RNA recognition motif (RRM). In vivo the bd...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Wang L,Yu J,Yin C,Li Z,Hu X,Pang Y

    更新日期:2002-12-01 00:00:00

  • Human heart cell proteins interacting with a C-terminally truncated 2A protein of coxsackie B3 virus: identification by the yeast two-hybrid system.

    abstract::Protein 2A is a non-structural protein of coxsackievirus B3 (CVB3), an important human pathogen that can cause a variety of human diseases. Protein 2A not only participates in viral life cycle, but also regulates host cell functions; however, the underlying mechanisms remain poorly understood. In order to better under...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Zhao T,Huang X,Xia Y

    更新日期:2016-04-01 00:00:00

  • Cleavage of transcripts of foot and mouth disease virus (FMDV), Asia1 serotype, by ribozymes targeted to the VP3 and VP4 genes.

    abstract::Two ribozyme genes were designed to cut within the VP4 and VP3 sequences of foot and mouth disease virus (FMDV) Asia1 serotype genome. The two genes were synthesized and cloned into pBluescript under the control of the T3 promoter. The ribozyme designed to cut the VP4 gene contained two catalytic sequences targeted to...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Stram Y,Molad T

    更新日期:1995-01-01 00:00:00

  • Analysis of the biological and molecular variability of Watermelon mosaic virus isolates from Iran.

    abstract::Watermelon mosaic virus (WMV) is one of the most important viruses that causes different symptoms in Cucurbitaceae. WMV is a potyvirus with a worldwide distribution, but occurs most commonly in temperate and Mediterranean regions. Cucurbit species grown in Yazd, Esfahan, West Azerbaijan, Hormozgan, and Kerman province...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Sharifi M,Massumi H,Heydarnejad J,Hosseini Pour A,Shaabanian M,Rahimian H

    更新日期:2008-12-01 00:00:00

  • Human T-cell leukemia virus type 1 Tax induces an aberrant clustering of the tumor suppressor Scribble through the PDZ domain-binding motif dependent and independent interaction.

    abstract::Human T-cell leukemia virus type 1 (HTLV-1) is a causative agent of adult T-cell leukemia. HTLV-1 Tax1 transforming protein interacts with several PDZ domain-containing proteins, and the interaction is associated with the transforming activities of Tax1 as well as persistent HTLV-1 infection. In this study, we show th...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Okajima M,Takahashi M,Higuchi M,Ohsawa T,Yoshida S,Yoshida Y,Oie M,Tanaka Y,Gejyo F,Fujii M

    更新日期:2008-10-01 00:00:00

  • Emergence of rabbit haemorrhagic disease virus 2 in the archipelago of Madeira, Portugal (2016-2017).

    abstract::We report the detection of rabbit haemorrhagic disease virus 2 (RHDV2) in the Madeira archipelago, Portugal. Viral circulation was confirmed by RT-qPCR and vp60 sequencing. Epidemiological data revealed the outbreak initiated in October 2016 in Porto Santo affecting wild and domestic rabbits. It was then detected thre...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Carvalho CL,Silva S,Gouveia P,Costa M,Duarte EL,Henriques AM,Barros SS,Luís T,Ramos F,Fagulha T,Fevereiro M,Duarte MD

    更新日期:2017-12-01 00:00:00

  • A synthetic peptide derived from domain III envelope glycoprotein of Dengue virus induces neutralizing antibody.

    abstract::Dengue virus (DENV) is an arthropod-borne human pathogen that represents a severe public health threat in both endemic and non-endemic regions. So far, there is no licensed vaccine or specific drugs available for dengue fever. A fifteen-amino-acid-long peptide that includes the NGR motif was chemically synthesized and...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Mary JA,Jittmittraphap A,Chattanadee S,Leaungwutiwong P,Shenbagarathai R

    更新日期:2018-02-01 00:00:00

  • Prevalence of TT virus and GBV-C infections among patients with liver diseases and the general population in Shanghai, China.

    abstract::To determine the prevalence of TT virus (TTV) and GB virus C/hepatitis G virus (GBV-C) infections among patients with liver disease and the general population in Shanghai, China, we studied 90 patients with liver diseases (acute hepatitis, 28; chronic hepatitis, 27; liver cirrhosis, 20; hepatocellular carcinoma, 15) a...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Ding X,Mizokami M,Kang LY,Cao K,Orito E,Tanaka Y,Ueda R,Sasaki M

    更新日期:1999-01-01 00:00:00

  • Characterization of white spot syndrome virus VP52B and its interaction with VP26.

    abstract::White spot syndrome virus (WSSV) is one of the major pathogens of cultured shrimp. Identification of envelope protein interactions has become a central issue for the understanding of WSSV assembly. In this paper, WSSV envelope protein VP52B was fused with GST-tag and expressed in Escherichia coli BL-21(DE3). Immunogol...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Lin F,Jie Z,Hou L,Li F,Yang F

    更新日期:2015-02-01 00:00:00

  • Emerging viruses in the genus Comovirus.

    abstract::The intraspecies variability of capsid proteins of five viruses of the genus Comovirus was established. Inclusion of both capsid proteins to the sequence analysis reduces some uncertainties about species/strains demarcation criteria in the Comovirus genus. New approach is proposed for discrimination of Turnip ringspot...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Petrzik K,Koloniuk I

    更新日期:2010-04-01 00:00:00

  • Searching for a new putative cryptic virus in Pinus sylvestris L.

    abstract::Double-stranded RNAs (dsRNAs) were detected in different pine populations in Germany and Hungary. Two dsRNA species of 1.5 and 1.58 kbp, respectively, persisted in the same trees for at least 2 years and their presence was not associated with any symptoms. The dsRNAs were found to sediment in the VLP (virus-like parti...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Veliceasa D,Enünlü N,Kós PB,Köster S,Beuther E,Morgun B,Deshmukh SD,Lukács N

    更新日期:2006-04-01 00:00:00

  • A novel Enterovirus 96 circulating in China causes hand, foot, and mouth disease.

    abstract::Enterovirus 96 (EV-96) is a recently described member of the species Enterovirus C and is associated with paralysis and myelitis. In this study, using metagenomic sequencing, we identified a new enterovirus 96 strain (EV-96-SZ/GD/CHN/2014) as the sole pathogen causing hand, foot, and mouth disease (HFMD). A genomic co...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Xu Y,Sun Y,Ma J,Zhou S,Fang W,Ye J,Tan L,Ji J,Luo D,Li L,Li J,Fang C,Pei N,Shi S,Liu X,Jiang H,Gong S,Xu X

    更新日期:2017-06-01 00:00:00

  • Vaccinia virus recombinants expressing rabiesvirus glycoprotein protect against rabies.

    abstract::Six recombinants of New York Board of Health (NYBH) vaccinia virus containing cDNA for Challenge Virus Standard (CVS) rabiesvirus glycoprotein (G) were produced by directing gene insertion into the vaccinia thymidine kinase (TK) locus. To regulate expression of G the promoter P7.5 (functions at early and late times po...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Esposito J,Brechling K,Baer G,Moss B

    更新日期:1987-11-01 00:00:00

  • Identification and characterization of the UL24 gene product of herpes simplex virus type 2.

    abstract::The UL24 gene of herpes simplex virus type 2 (HSV-2) is predicted to encode a 281 amino acid protein with a molecular mass of 30.5 kDa. In this study, the HSV-2 UL24 gene product has been identified by using a rabbit polyclonal antiserum produced against a recombinant protein containing the full-length UL24 gene produ...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Hong-Yan Z,Murata T,Goshima F,Takakuwa H,Koshizuka T,Yamauchi Y,Nishiyama Y

    更新日期:2001-06-01 00:00:00

  • Pigeon paramyxovirus type 1 variants with polybasic F protein cleavage site but strikingly different pathogenicity.

    abstract::Newcastle disease viruses (NDV) isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) are mostly of mesogenic pathotype and characterized by a polybasic amino acid sequence motif at the fusion protein (F) cleavage site. This feature also applies to isolate R75/98 from Germany. Its genome consists of 15,192 nucle...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Heiden S,Grund C,Höper D,Mettenleiter TC,Römer-Oberdörfer A

    更新日期:2014-12-01 00:00:00

  • Biophysical and biochemical properties of baculovirus-expressed CaMV P1 protein.

    abstract::Cauliflower mosaic virus (CaMV) gene I encodes a protein (P1) that has been implicated in the control of virus movement in infected plants. To assist in the characterization of the mechanism of action of P1, gene I has been expressed efficiently in Spodoptera frugiperda (Sf) cells using recombinant baculovirus. Contro...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Maule AJ,Usmany M,Wilson IG,Boudazin G,Vlak JM

    更新日期:1992-01-01 00:00:00

  • Genomic characterization of a novel partitivirus infecting. Aspergillus ochraceus.

    abstract::Three double-stranded RNA (dsRNA) segments from Aspergillus ochraceus isolate FA 0611, designated as AoR1, AoR2, and AoR3, were cloned and sequenced. AoR1 was identical with AoV dsRNA 1 previously reported from A. ochraceus ATCC 28706, which putatively encoded an RNA-dependent RNA polymerase of an unidentified mycovir...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Liu W,Duns G,Chen J

    更新日期:2008-12-01 00:00:00

  • Molecular evidence for the existence of two distinct subgroups in cucumber mosaic cucumovirus.

    abstract::Infectious full-length cDNA clones from the genomic RNAs of a subgroup II cucumber mosaic cucumovirus strain (Trk7) were obtained. Sequence analysis of the whole genome revealed strong homology (99%) to the genome of Q-CMV, the only subgroup II strain whose entire genomic nucleotide sequence had been available in the ...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Szilassy D,Salánki K,Balázs E

    更新日期:1999-01-01 00:00:00

  • Complete sequence of the RNA genome of pneumonia virus of mice (PVM).

    abstract::Pneumonia virus of mice (PVM) is an enveloped RNA-containing virus of Family Paramyxoviridae. Sequences had been determined previously for a number of PVM genes, although these represented cloned cDNAs rather than consensus sequences. Sequences were not available for the 3' -leader and 5' -trailer regions that constit...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Krempl CD,Lamirande EW,Collins PL

    更新日期:2005-03-01 00:00:00

  • Phylogenetic analysis of porcine astrovirus in domestic pigs and wild boars in South Korea.

    abstract::Porcine astrovirus (PAstV) belongs to genetically divergent lineages within the genus Mamastrovirus. In this study, 25/129 (19.4 %) domestic pig and 1/146 (0.7 %) wild boar fecal samples tested in South Korea were positive for PAstV. Positive samples were mainly from pigs under 6 weeks old. Bayesian inference (BI) tre...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Lee MH,Jeoung HY,Park HR,Lim JA,Song JY,An DJ

    更新日期:2013-02-01 00:00:00

  • Assessment of HCV genotypes in Yunnan Province of Southwest China.

    abstract::Recently, we reported that the frequency of hepatitis C virus (HCV) genotypes and subtypes has rapidly changed among intravenous drug users (IDUs) in Yunnan Province over the last 5 years; this is especially true for subtype 6a which has increased in frequency from 5 to 15%. Here, we assessed 120 HCV-positive plasma s...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Li Q,Yao Y,Shen Y,Cao D,Li Y,Zhang S,Cun W,Sun M,Yu J,Shi L,Dong S

    更新日期:2017-04-01 00:00:00

  • The VP3 gene of human group C rotavirus.

    abstract::The complete nucleotide sequence of genome segment 4 from the human group C rotavirus (Bristol strain) was determined. Comparison of the nucleotide sequences of the genome termini with the consensus 5' and 3' terminal non-coding sequences of the human group C rotavirus genome revealed characteristic 5' and 3' sequence...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Samarbaf-Zadeh AR,Lambden PR,Green SM,Deng Y,Caul EO,Clarke IN

    更新日期:1996-01-01 00:00:00

  • Adaptation of wild-type measles virus to cotton rat lung cells: E89K mutation in matrix protein contributes to its fitness.

    abstract::Wild-type measles virus (wtMeV) adapted well to cotton rat lung (CRL) cells after serial passages. In order to evaluate the contributions of the individual genes of wtMeV for adaptation, whole genome sequences of the adapted and original viruses were determined and analyzed. The results showed that there were two muta...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Dong JB,Saito A,Mine Y,Sakuraba Y,Nibe K,Goto Y,Komase K,Nakayama T,Miyata H,Iwata H,Haga T

    更新日期:2009-12-01 00:00:00

  • Identification and characterization of a novel Tritimovirus species isolated from wild Trisetum flavescens L., family Poaceae.

    abstract::Yellow oat-grass plants (Trisetum flavescens L.) with mild mosaic and pronounced dwarfing symptoms were observed at different locations in the Czech Republic. Electron microscope observations of symptomatic plants revealed the presence of filamentous particles and inclusion bodies characteristic of the family Potyviri...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Hassan M,Sirlova L,Jokes M,Vacke J

    更新日期:2009-08-01 00:00:00

  • Oncolytic viruses: adenoviruses.

    abstract::Tumor-selectively replicating (oncolytic) viruses are promising tools for therapy of solid cancers and have been initially developed to achieve potent tumor lysis with acceptable side effects on healthy tissue. However, in recent years, oncolytic viruses have been recognized as therapeutic vehicles exhibiting multipro...

    journal_title:Virus genes

    pub_type: 杂志文章,评审


    authors: Niemann J,Kühnel F

    更新日期:2017-10-01 00:00:00

  • Unique evolution characteristics of the envelope protein of EIAV(LN₄₀), a virulent strain of equine infectious anemia virus.

    abstract::The Chinese equine infectious anemia virus (EIAV) virulent strain EIAV(LN40) is derived from a naturally occurring virus by continuously passing in horses for 16 generations. Its genome sequence is 23% different from that of the American strains or the Japanese strains, and the variation of envelope gp90 surface unit ...

    journal_title:Virus genes

    pub_type: 杂志文章


    authors: Wang X,Wang S,Lin Y,Jiang C,Ma J,Zhao L,Lv X,Wang F,Shen R,Zhou J

    更新日期:2011-04-01 00:00:00