Identification of specific amino acid residues of adenovirus 12 E1A involved in transformation and p300 binding.

abstract：:Marek's disease (MD), a lymphoproliferative disease of chicken is caused by a highly cell-associated alpha-herpesvirus, Marek's disease virus (MDV). MDV replicates in chicken lymphocytes and establishes a latent infection within CD4(+) T cells. The expression analysis of limited viral transcripts have revealed differe...

journal_title：Virus genes

authors： Heidari M,Huebner M,Kireev D,Silva RF

更新日期：2008-04-01 00:00:00

abstract：:Cell mediated immunity (CMI) is crucial for the defense against viruses. Cytotoxic T lymphocytes (CTLs) play a major role in CMI. They recognize endogenous antigenic peptides presented by antigen presenting cells in association with the major histocompatibility complex (MHC) class I molecules. The elucidation of the s...

journal_title：Virus genes

authors： Hegde NR,Srikumaran S

更新日期：1997-01-01 00:00:00

abstract：:Orf virus (ORFV), a typical member of the Parapoxvirus genus within the family Poxviridae, which is the causative agent of Orf, a common epitheliotropic viral disease of sheep, goats, wild ruminants, and humans. In the present study, we sequenced the complete genomic sequences of two ORFV strains (ORFV-SY17, isolated ...

journal_title：Virus genes

authors： Zhong J,Guan J,Zhou Y,Cui S,Wang Z,Zhou S,Xu M,Wei X,Gao Y,Zhai S,Song D,He W,Gao F,Zhao K

更新日期：2019-08-01 00:00:00

abstract：:Historically, viral evolution has often been considered from the perspective of the ability of the virus to maintain viral pathogenic fitness by causing disease. A predator-prey model has been successfully applied to explain genetically variable quasi-species of viruses, such as influenza virus and human immunodeficie...

journal_title：Virus genes

authors： Shadan FF,Villarreal LP

更新日期：1995-01-01 00:00:00

abstract：:Canine distemper (CD) is a highly contagious, often fatal, multisystemic, and incurable disease in dogs and other carnivores, which is caused by canine distemper virus (CDV). Although vaccines have been used as the principal means of controlling the disease, CD has been reported in vaccinated animals. The hemoagglutin...

journal_title：Virus genes

authors： Li W,Li T,Liu Y,Gao Y,Yang S,Feng N,Sun H,Wang S,Wang L,Bu Z,Xia X

更新日期：2014-08-01 00:00:00

abstract：:One of the consequences of equine herpesvirus 1 (EHV-1) infection in the natural host is a neurological disease that can lead to paralysis. The pathology associated with EHV-1-induced neurological disease includes vasculitis of the small blood vessels within the central nervous system and subsequent damage to the surr...

journal_title：Virus genes

authors： Frampton AR Jr,Smith PM,Zhang Y,Grafton WD,Matsumura T,Osterrieder N,O'Callaghan DJ

更新日期：2004-08-01 00:00:00

abstract：:Foot-and-mouth disease (FMD) is the most contagious and devastating disease of livestock. Our previous studies demonstrated that TK(-)/gG(-)/P1(+), a recombinant expressing the FMDV capsid precursor protein (P1) based on attenuated pseudorabies virus (PRV) TK(-)/gG(-), could be used as a recombinant vaccine to protect...

journal_title：Virus genes

authors： He Y,Qian P,Zhang K,Yao Q,Wang D,Xu Z,Wu B,Jin M,Xiao S,Chen H

更新日期：2008-04-01 00:00:00

abstract：:The search for retroviruses in human cancer cells has advanced with the discoveries of the retroviral reverse transcriptase, DNA hybridization and sequencing techniques, and polymerase chain reaction (PCR) technology. Each technological advancement has led to a better refinement and a better understanding of latent en...

journal_title：Virus genes

authors： Becker Y

更新日期：1995-02-01 00:00:00

abstract：:Pneumonia virus of mice (PVM) is an enveloped RNA-containing virus of Family Paramyxoviridae. Sequences had been determined previously for a number of PVM genes, although these represented cloned cDNAs rather than consensus sequences. Sequences were not available for the 3' -leader and 5' -trailer regions that constit...

journal_title：Virus genes

authors： Krempl CD,Lamirande EW,Collins PL

更新日期：2005-03-01 00:00:00

abstract：:This study describes the results of the sequencing and analysis of segments of Blocks II and III of the RNA polymerase L gene of Rabies virus isolates from different reservoir species of Brazil. The phylogenetic relations of the virus were determined and a variety of species-specific nucleotides were found in the anal...

journal_title：Virus genes

authors： Carnieli P Jr,de Novaes Oliveira R,de Oliveira Fahl W,de Carvalho Ruthner Batista HB,Scheffer KC,Iamamoto K,Castilho JG

更新日期：2012-08-01 00:00:00

abstract：:The broad distribution and prevalence of H3 subtype influenza viruses in avian and mammalian hosts constitutes a global threat to both human and veterinary health. In this present study, six H3N8 influenza viruses isolated from domestic ducks during 2004-2005 in northern China were genetically and phylogenetically cha...

journal_title：Virus genes

authors： Pu J,Liu QF,Xia YJ,Fan YL,Brown EG,Tian FL,Liu JH

更新日期：2009-02-01 00:00:00

abstract：:An evolutionary analysis was conducted of 354 hemagglutinin (HA) and 208 neuraminidase (NA) genes, including newly generated sequences of 5 HA and 30 NA, of Egyptian H5N1 clade 2.2.1 viruses isolated from poultry and humans. Five distinct phylogenetically distinguishable clusters arose from a monophyletic origin since...

journal_title：Virus genes

authors： Abdelwhab EM,Arafa AS,Stech J,Grund C,Stech O,Graeber-Gerberding M,Beer M,Hassan MK,Aly MM,Harder TC,Hafez HM

更新日期：2012-08-01 00:00:00

abstract：:In our transient expression assays, the IE180 and TK promoters were markedly suppressed by the EP0 of the pseudorabies virus strains Ea and Fa (EP0/Ea, EP0/Fa). This is in contrast with the transactivating activity of EP0 from strain YS-81 (EP0/YS-81) in previous studies. Amino acid sequence alignment revealed several...

journal_title：Virus genes

authors： Guo H,Zhou R,Xi Y,Xiao S,Chen H

更新日期：2009-04-01 00:00:00

abstract：:Straw-colored fruit bats (Eidolon helvum), which have been identified as natural hosts for several zoonotic pathogens, such as lyssaviruses, henipaviruses, and ebolavirus, are associated with human settlements in Nigeria where they are commonly consumed as a delicacy. However, information on the viruses harbored by th...

journal_title：Virus genes

authors： Leopardi S,Oluwayelu D,Meseko C,Marciano S,Tassoni L,Bakarey S,Monne I,Cattoli G,De Benedictis P

更新日期：2016-08-01 00:00:00

abstract：:Kenya is one of the high endemic zones for hepatitis B virus (HBV) infection. The consensuses on prevalence of the HBV genotypes and the existence of their variants have not been fully established in Kenya. Hence, there is a need to further monitor the diversity of HBV. This study aimed to extend the current molecular...

journal_title：Virus genes

authors： Kwange SO,Budambula NL,Kiptoo MK,Okoth F,Ochwoto M,Oduor M,Kimotho JH

更新日期：2013-12-01 00:00:00

abstract：:Novel duck reovirus (NDRV), the prototype strain of the species Avian orthoreovirus (ARV), is associated with high mortality in Pekin ducklings. σC is an outer capsid protein encoded by the S1 genome segment of NDRV which mediates attachment to host cells. Our previous studies using immunoprecipitation and mass spectr...

journal_title：Virus genes

authors： Xiao R,Mi X,Sun J,Ding M,Li C,Zhu J,Liu G,Ma W,Zhou H,Chen Z

更新日期：2020-06-01 00:00:00

abstract：:Macropodid herpesvirus 1 (MaHV-1) is an unclassified alphaherpesvirus linked with the fatal infections of kangaroos and other marsupials. During the characterisation of the internal repeat region of MaHV-1, an open reading frame (ORF) encoding for thymidylate synthase (TS) gene was identified and completely sequenced....

journal_title：Virus genes

authors： Guliani S,Polkinghorne I,Smith GA,Young P,Mattick JS,Mahony TJ

更新日期：2002-06-01 00:00:00

abstract：:The complete nucleotide sequence of a virus isolated from soybean (Glycine max (L.) Merr.) in China, previously identified as a new strain of Tobacco necrosis virus A (TNV-A) based on its biological, serological properties, and coat protein (CP) sequence and named as TNV-A C, was determined and compared with that of T...

journal_title：Virus genes

authors： Xi D,Li J,Han C,Li D,Yu J,Zhou X

更新日期：2008-02-01 00:00:00

abstract：:Staphylococcus aureus is a well-known pathogen that causes several serious diseases in humans and animals. As part of the efforts to control this pathogen, a newly isolated bacteriophage, SA12, which specifically targets S. aureus, was characterized, and its genome was completely sequenced. Host range and bacteriophag...

journal_title：Virus genes

authors： Chang Y,Lee JH,Shin H,Heu S,Ryu S

更新日期：2013-10-01 00:00:00

abstract：:Nucleotide sequencing was performed on part of the medium and large genome segments of 17 Cache Valley virus (CVV) isolates from the Yucatan Peninsula of Mexico. Alignment of these sequences to all other sequences in the Genbank database revealed that they have greatest nucleotide identity (97-98 %) with the equivalen...

journal_title：Virus genes

authors： Blitvich BJ,Loroño-Pino MA,Garcia-Rejon JE,Farfan-Ale JA,Dorman KS

更新日期：2012-08-01 00:00:00

abstract：:Tomato mosaic virus (ToMV), a member of the genus Tobamovirus, infects several ornamental and horticultural crops worldwide. In this study, the nucleotide sequences of the coat protein gene of worldwide ToMV isolates were analyzed to estimate the genetic structure and diversity of this virus and the involved evolution...

journal_title：Virus genes

authors： Rangel EA,Alfaro-Fernández A,Font-San-Ambrosio MI,Luis-Arteaga M,Rubio L

更新日期：2011-12-01 00:00:00

abstract：:By using a phage vector (lambda ZAP II) and the mRNA extracted from IMR-32 cells infected with the RC.HL strain of rabies virus, we constructed a cDNA library from which four nucleoprotein (N)-specific cDNA clones were obtained by Southern blot hybridization. These clones contained a cDNA insert of about 1.4 kb, in wh...

journal_title：Virus genes

authors： Goto H,Minamoto N,Ito H,Sugiyama M,Kinjo T,Mannen K,Mifune K,Kawai A

更新日期：1994-03-01 00:00:00

abstract：:The S2 glycoprotein and membrane (M) protein genes and S1 glycoprotein and nucleocapsid (N) genes of 11 Korean infectious bronchitis virus (IBV) isolates were amplified by RT-PCR, cloned, and sequenced. The resultant nucleotide sequences were compared with the published sequences for non-Korean IBV strains. Korean IBV...

journal_title：Virus genes

authors： Song JE,Jeong WG,Sung HW,Kwon HM

更新日期：2013-04-01 00:00:00

abstract：:Human parainfluenza virus type 3 (HPIV3) causes the majority of childhood viral pneumonia around the world. Fusing the viral and target cell membranes is crucial for its entry into target cells, and the fusion process requires the concerted actions of two viral glycoproteins: hemagglutinin-neuraminidase (HN) and fusio...

journal_title：Virus genes

authors： Liu Y,Chi M,Wen H,Zhao L,Song Y,Liu N,Chi L,Wang Z

更新日期：2020-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major global health issue. Although the search for HCV treatments has resulted in great achievements, the current treatment methods have limitations, and new methods and drugs for hepatitis C treatment are still required. The aim of the present study was to investigate the effect...

journal_title：Virus genes

authors： Dai R,Xiao X,Peng F,Li M,Gong G

更新日期：2016-02-01 00:00:00

abstract：:Virus-like particles (VLPs, named HmTV1-17), about 40 nm in diameter were found in the violet root rot fungus Helicobasidium mompa Tanaka strain No. 17, which had been isolated from an apple tree. Purified preparations of HmTV1-17 contained two species of double-stranded RNA (dsRNA), designated 17L and 17S. cDNAs were...

journal_title：Virus genes

authors： Nomura K,Osaki H,Iwanami T,Matsumoto N,Ohtsu Y

更新日期：2003-05-01 00:00:00

abstract：:Dengue virus (DENV; Genus Flavivirus, Family Flaviviridae) has been circulating in Brazil since at least the mid-1980s and continues to be responsible for sporadic cases of Dengue fever and Dengue hemorrhagic fever throughout this country. Here, we describe the full genomes of two new Brazilian DENV-serotype 1 (DENV-1...

journal_title：Virus genes

authors： Carvalho SE,Martin DP,Oliveira LM,Ribeiro BM,Nagata T

更新日期：2010-02-01 00:00:00

abstract：:The complete genome sequence of Nootka lupine vein-clearing virus (NLVCV) was determined to be 4,172 nucleotides in length containing four open reading frames (ORFs) with a similar genetic organization of virus species in the genus Carmovirus, family Tombusviridae. The order and gene product size, starting from the 5'...

journal_title：Virus genes

authors： Robertson NL,Côté F,Paré C,Leblanc E,Bergeron MG,Leclerc D

更新日期：2007-12-01 00:00:00

abstract：:The varicella zoster virus (VZV) ORF4 protein, one of immediate-early genes protein, is associated with the tegument in purified virions. ORF4 protein functions at both transcriptional and post-transcriptional levels, present during different phase of whole VZV life cycle. ORF4 protein acts as a nucleocytoplasm shuttl...

journal_title：Virus genes

authors： Huang Y,Zhang J,Halawa MA,Yao S

更新日期：2014-04-01 00:00:00

abstract：:Spodoptera litura multicapsid nucleopolyhedrovirus (SpltMNPV) odv-e25 is 684 bp long, potentially encoding 227 amino acids with a predicted molecular weight of 24.9 kDa. Homology analysis indicated that SpltMNPV ODV-E25 has 35-65% amino acid identity with that of other known baculoviruses. RT-PCR results revealed that...

journal_title：Virus genes

authors： Li Z,Pan L,Yu H,Li S,Zhang G,Pang Y

更新日期：2006-02-01 00:00:00