Abstract:
:We have determined the 5' and 3' non-coding regions (NCR) of four dengue-2 viruses isolated from dengue patients with different clinical severities in Nakhon Phanom, Northeastern Thailand in 1993. The results were compared to prototype dengue-2 strains and were found to have highest homology with the New Guinea C strain. The sequence of the 5' NCR was completely conserved among all 4 isolates and were identical to the sequence of the New Guinea C strain. Homology of the 3' NCR sequence of the four isolates with the prototype strain ranged from 97.3 to 97.8%. Isolate ThNH-p11/93 from a mild dengue fever case showed the highest divergence from the prototype strain and the rest of the isolates from severe hemorrhagic cases, (1.11%). This includes a change in triad 297-299 nucleotides from the 3' terminus. Computer predicted secondary structures showed that isolate ThNHp-11/93 had significant structural differences from the other three isolates at this region.
journal_name
Virus Genesjournal_title
Virus genesauthors
Mangada MN,Igarashi Adoi
10.1023/a:1007914520454subject
Has Abstractpub_date
1997-01-01 00:00:00pages
5-12issue
1eissn
0920-8569issn
1572-994Xjournal_volume
14pub_type
杂志文章相关文献
VIRUS GENES文献大全abstract::The S2 glycoprotein and membrane (M) protein genes and S1 glycoprotein and nucleocapsid (N) genes of 11 Korean infectious bronchitis virus (IBV) isolates were amplified by RT-PCR, cloned, and sequenced. The resultant nucleotide sequences were compared with the published sequences for non-Korean IBV strains. Korean IBV...
journal_title:Virus genes
pub_type: 信件
doi:10.1007/s11262-012-0856-0
更新日期:2013-04-01 00:00:00
abstract::Korean field infectious bursal disease viruses (IBDVs) were isolated from IBDV suspected commercial chickens. A previous study revealed that these IBDV field isolates were virulent or very virulent IBDVs. The isolates were passaged three times in the chorioallantoic membrane of specific-pathogen-free embryonated chick...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/b:viru.0000025776.52661.b0
更新日期:2004-04-01 00:00:00
abstract::To determine the prevalence of TT virus (TTV) and GB virus C/hepatitis G virus (GBV-C) infections among patients with liver disease and the general population in Shanghai, China, we studied 90 patients with liver diseases (acute hepatitis, 28; chronic hepatitis, 27; liver cirrhosis, 20; hepatocellular carcinoma, 15) a...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1008188623062
更新日期:1999-01-01 00:00:00
abstract::We have examined sequence variability among nine isolates of hop stunt viroid (HSVd) collected from hop gardens in Tohoku district in Japan, the only area in the world where hop stunt disease is endemic. Six different consensus and one-consensus sequences as well as 12 sequence variants were detected in the nine HSVd-...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1008182302704
更新日期:2001-01-01 00:00:00
abstract::Enterovirus 96 (EV-96) is a recently described member of the species Enterovirus C and is associated with paralysis and myelitis. In this study, using metagenomic sequencing, we identified a new enterovirus 96 strain (EV-96-SZ/GD/CHN/2014) as the sole pathogen causing hand, foot, and mouth disease (HFMD). A genomic co...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1431-5
更新日期:2017-06-01 00:00:00
abstract::The nucleotide sequence of the 3' terminal region of potato virus Y (PVY) was determined. Starting with a poly(A) tail of 18 residues a non-coding region of 335 nucleotides precedes the region encoding for the virus coat protein (cp) 801 nucleotides long ending with a TGA. This region was located by comparing the pred...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF00572704
更新日期:1988-06-01 00:00:00
abstract::The main function of baculoviral chitinase protein (V-CHIA) is to promote the final liquefaction of infected host larvae, facilitating the dispersion of occlusion bodies (OBs) in the environment. In this study, a v-chiA from Epinotia aporema Granulovirus (EpapGV) was identified and characterized. The 1,713 base pairs ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-013-1019-7
更新日期:2014-04-01 00:00:00
abstract::Complementary DNAs (cDNAs) to the RNA genome of a necrotic strain of potato virus Y in Japan (Hokkaido Univ. isolate of PVY-T:PVY-TH) were synthesized and cloned into a plasmid pBR322. About 4.3 kbp of the cDNA sequence containing the 3'-poly(A) tract of PVY-TH was inserted into a recombinant plasmid pBRYT88. The coat...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF00570028
更新日期:1990-12-01 00:00:00
abstract::Parvoviridae, which are classified into two subfamilies Parvovirinae and Densovirinae, can infect both vertebrate and insects and are related to a wide range of diseases in insects, animals, and humans. In this report, several new parvoviruses were identified in swine sera collected in southeastern China. The sequence...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-010-0506-3
更新日期:2010-10-01 00:00:00
abstract::Mal de Río Cuarto virus (MRCV) is a newly described species of the genus Fijivirus, family Reoviridae. Compared with other plant-infecting genus of the family, the function and localization of MRCV and other Fijivirus proteins are poorly understood. Through analysis of viral particle purifications, we positively ident...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-009-0345-2
更新日期:2009-06-01 00:00:00
abstract::Porcine reproductive and respiratory syndrome (PRRS) is a swine disease of major economic importance that causes reproductive and respiratory problems in pigs. In the present study, one strain of porcine reproductive and respiratory syndrome virus (PRRSV) was isolated in Xinjiang province, Northwest China, designated ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-014-1122-4
更新日期:2015-02-01 00:00:00
abstract::A BK virus isolate cloned from the urine of an immunosuppressed patient was identified as the WW strain. Fine mapping using four base-pair restriction enzymes identified a number of small deletions and insertions relative to prototype BK. The finding of a transcriptional control region with a structure similar to that...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF00315259
更新日期:1989-03-01 00:00:00
abstract::An evolutionary analysis was conducted of 354 hemagglutinin (HA) and 208 neuraminidase (NA) genes, including newly generated sequences of 5 HA and 30 NA, of Egyptian H5N1 clade 2.2.1 viruses isolated from poultry and humans. Five distinct phylogenetically distinguishable clusters arose from a monophyletic origin since...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-012-0758-1
更新日期:2012-08-01 00:00:00
abstract::Papillomaviruses are small and complex viruses with circular DNA genome that belongs to the Papillomavirus family, which comprises at least 39 genera. The bovine papillomavirus (BPV) causes an infectious disease that is characterized by chronic and proliferative benign tumors that affect cattle worldwide. In the prese...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1406-y
更新日期:2017-02-01 00:00:00
abstract::A maximum clade credibility tree constructed using the full-length spike (S) and hemagglutinin-esterase genes revealed that Vietnamese Bovine coronavirus (BCoV) strains belong to a single cluster (C1); therefore, they might share a common origin with Cuban and Chinese BCoV strains. The omega values of cluster 1 (C1) a...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01647-1
更新日期:2019-06-01 00:00:00
abstract::Jaagsiekte sheep retrovirus (JSRV) is the causative agent of ovine pulmonary adenocarcinoma (OPA), a contagious lung cancer in sheep. Previous studies have shown that the JSRV envelope protein (Env) functions as an oncogene, in that it can morphologically transform rodent fibroblast and epithelial cell lines. To obtai...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-006-0031-6
更新日期:2007-08-01 00:00:00
abstract::Genetic diversity of eight Grapevine leafroll-associated virus 1 (GLRaV-1) isolates recovered from grapevines in three distinct locations in the Czech Republic and Slovakia was characterised by restriction fragment length polymorphism (RFLP) analysis and by sequencing of cloned 540 bp fragment of the heat shock protei...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-005-3236-1
更新日期:2005-12-01 00:00:00
abstract::Cap-independent translations of viral RNAs of enteroviruses and rhinoviruses, cardioviruses and aphthoviruses, hepatitis A and C viruses (HAV and HCV), and pestivirus are initiated by the direct binding of 40S ribosomal subunits to a cis-acting genetic element termed the internal ribosome entry site (IRES) or ribosome...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF00572952
更新日期:1996-01-01 00:00:00
abstract::Dengue virus (DENV) is an arthropod-borne human pathogen that represents a severe public health threat in both endemic and non-endemic regions. So far, there is no licensed vaccine or specific drugs available for dengue fever. A fifteen-amino-acid-long peptide that includes the NGR motif was chemically synthesized and...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1508-1
更新日期:2018-02-01 00:00:00
abstract::Although Sapovirus (Caliciviridae) has been accepted as one of the causes of acute gastroenteritis worldwide, little is known about the genetic characteristics of the whole genome of sapoviruses in China, especially those that infect humans. Here we report the complete genome sequence of a sapovirus strain, Human/Zhej...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1343-9
更新日期:2016-10-01 00:00:00
abstract::Arenaviridae is a worldwide distributed family, of enveloped, single stranded, RNA viruses. The arenaviruses were divided in two major groups (Old World and New World), based on serological properties and genetic data, as well as the geographic distribution. In this study the phylogenetic relationship among the member...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1007993525052
更新日期:1998-01-01 00:00:00
abstract::Bovine viral diarrhea virus (BVDV) belongs to the Pestivirus genus of the Flaviviridae family and has worldwide distribution, being one of the main causes of economic losses in cattle raising. The genome of pestiviruses is a single strand of positive-sense RNA with a length of 12.3 kb, which encodes one open reading f...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01756-2
更新日期:2020-08-01 00:00:00
abstract::Herpes simplex virus type 1 (HSV-1) reactivates from a small fraction of latently infected neurons in vivo and neuronally differentiated (ND), quiescently infected (QIF)-PC12 cells in vitro. This may be the result of reactivation initiating in only a few cells, or reactivation followed by premature termination of the ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-005-0052-6
更新日期:2006-10-01 00:00:00
abstract::Tumor-selectively replicating (oncolytic) viruses are promising tools for therapy of solid cancers and have been initially developed to achieve potent tumor lysis with acceptable side effects on healthy tissue. However, in recent years, oncolytic viruses have been recognized as therapeutic vehicles exhibiting multipro...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-017-1488-1
更新日期:2017-10-01 00:00:00
abstract::Chinese equine infectious anemia virus (EIAV) attenuated vaccine is the first lentiviral vaccine with a successful application. In order to understand the correlation of viral genomic mutations with viral attenuation and with induced immunoprotective properties, we analyzed the proviral genome sequences of the EIAV-at...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-010-0491-6
更新日期:2010-08-01 00:00:00
abstract::Twenty-three CSFV isolates recovered from field outbreaks in various parts of India during 2006-2009 were used for genetic analysis in the NS5B region (409 nts). Seventeen of these were studied earlier [16] in the 5'UTR region. Phylogenetic analysis indicated the continued dominance of subgroup 1.1 strains in the coun...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-011-0572-1
更新日期:2012-02-01 00:00:00
abstract::The first genome of a virus infecting a representative of the eubacterial genus Actinoplanes is presented. Phage phiAsp2 has a circularly permutated chromosome that consists of 58,638 bp; its G/C-bias of 70.39% resembles the hosts G + C-content (71-73% within the genus). A total of 76 open reading frames (orfs) were i...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/B:VIRU.0000032795.17713.6c
更新日期:2004-08-01 00:00:00
abstract::Six recombinants of New York Board of Health (NYBH) vaccinia virus containing cDNA for Challenge Virus Standard (CVS) rabiesvirus glycoprotein (G) were produced by directing gene insertion into the vaccinia thymidine kinase (TK) locus. To regulate expression of G the promoter P7.5 (functions at early and late times po...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF00125682
更新日期:1987-11-01 00:00:00
abstract::Glycoprotein K (gK) encoded by the UL53 gene is the ninth out of eleven HSV glycoproteins (gps). The precursor gK (pgK) is a transmembrane protein with four hydrophobic domains, which consists of 338 amino acids. The UL53 gene has two initiation codons: the upper overlaps with the UL52 ORF, while the lower is located ...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1023/a:1008025520655
更新日期:1999-01-01 00:00:00
abstract::Herpesvirus saimiri induces acute lymphomas and leukemias in primates and rabbits. Sequence divergence of the right end unique region of the genome classifies virus strains into three groups (A, B, and C), and previous studies have demonstrated correlation between DNA grouping and oncogenicity. In order to relate diff...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF01703599
更新日期:1994-01-01 00:00:00