A novel Enterovirus 96 circulating in China causes hand, foot, and mouth disease.

abstract：:For millions of years viruses have adapted strategies to interfere with the immune defense of the host, which in turn has to deal with this challenge. In general the antiviral defense remains one step behind the pathogen. To achieve this strategic advantage large DNA-containing Viruses encode cellular homologues that ...

journal_title：Virus genes

authors： Raftery M,Müller A,Schönrich G

更新日期：2000-01-01 00:00:00

abstract：:Two ribozyme genes were designed to cut within the VP4 and VP3 sequences of foot and mouth disease virus (FMDV) Asia1 serotype genome. The two genes were synthesized and cloned into pBluescript under the control of the T3 promoter. The ribozyme designed to cut the VP4 gene contained two catalytic sequences targeted to...

journal_title：Virus genes

authors： Stram Y,Molad T

更新日期：1995-01-01 00:00:00

abstract：:Papillomaviruses are small and complex viruses with circular DNA genome that belongs to the Papillomavirus family, which comprises at least 39 genera. The bovine papillomavirus (BPV) causes an infectious disease that is characterized by chronic and proliferative benign tumors that affect cattle worldwide. In the prese...

journal_title：Virus genes

authors： da Silva FR,Daudt C,Cibulski SP,Weber MN,Varela AP,Mayer FQ,Roehe PM,Canal CW

更新日期：2017-02-01 00:00:00

abstract：:The envelope proteins of Chikungunya virus (CHIKV) are known to play crucial roles in viral infection and spread. Although the role of envelope proteins in viral infection has been studied, the cellular interactors of these proteins are still elusive. In the present study, the ectodomains of CHIKV envelope proteins (E...

journal_title：Virus genes

authors： Dudha N,Rana J,Rajasekharan S,Gabrani R,Gupta A,Chaudhary VK,Gupta S

更新日期：2015-04-01 00:00:00

abstract：:The varicella zoster virus (VZV) ORF4 protein, one of immediate-early genes protein, is associated with the tegument in purified virions. ORF4 protein functions at both transcriptional and post-transcriptional levels, present during different phase of whole VZV life cycle. ORF4 protein acts as a nucleocytoplasm shuttl...

journal_title：Virus genes

authors： Huang Y,Zhang J,Halawa MA,Yao S

更新日期：2014-04-01 00:00:00

abstract：:The California 99 (Cal99) variant of infectious bronchitis virus (IBV) was first recovered in 1999 from vaccinated broiler chicken flocks in Central California. The S1 hypervariable region of Cal99 genome was most closely related to Arkansas (Ark) serotype viruses. In this study, the complete genome of Cal99 was seque...

journal_title：Virus genes

authors： Mondal SP,Cardona CJ

更新日期：2007-06-01 00:00:00

abstract：:The genetic diversity of classical swine fever virus (CSFV) was studied by RT-PCR amplification and sequencing of a 409 bp fragment of the NS5B polymerase region. A total of 106 viruses isolated from 20 countries over a period of 52 years (1945-1997) were included in the phylogenetic study. The results showed that the...

journal_title：Virus genes

authors： Björklund H,Lowings P,Stadejek T,Vilcek S,Greiser-Wilke I,Paton D,Belák S

更新日期：1999-01-01 00:00:00

abstract：:Several important biological processes are performed by distinct functional domains found on replication-associated protein (Rep) encoded by AC1 of geminiviruses. Two truncated forms of replicase (tAC1) gene, capable of expressing only the N-terminal 669 bp (5'AC1) and C-terminal 783 bp (3'AC1) nucleotides cloned unde...

journal_title：Virus genes

authors： Hashmi JA,Zafar Y,Arshad M,Mansoor S,Asad S

更新日期：2011-04-01 00:00:00

abstract：:The near-complete (99.7 %) genome sequence of a novel Russian Plum pox virus (PPV) isolate Pk, belonging to the strain Winona (W), has been determined by 454 pyrosequencing with the exception of the thirty-one 5'-terminal nucleotides. This region was amplified using 5'RACE kit and sequenced by the Sanger method. Genom...

journal_title：Virus genes

authors： Sheveleva A,Kudryavtseva A,Speranskaya A,Belenikin M,Melnikova N,Chirkov S

更新日期：2013-10-01 00:00:00

abstract：:The thymidylate synthase (TS, EC 2.1.1.45) is essential for the de novo synthesis of dTMP in pro- and eucaryotic organisms. Consequently it plays a major role in the replication of the DNA genome of a cell or a DNA virus. The gene encoding the TS of Chilo iridescent virus (CIV) was identified by nucleotide sequence an...

journal_title：Virus genes

authors： Müller K,Tidona CA,Bahr U,Darai G

更新日期：1998-01-01 00:00:00

abstract：:A 13 amino acid residue insertion was found in the N-terminal region of the coat protein of several Maize dwarf mosaic virus isolates (MDMV). These insertions seem to be the result of a direct duplication event, but differ in some positions. In order to evaluate the influence of the insertion on the RNA secondary stru...

journal_title：Virus genes

authors： Petrik K,Sebestyén E,Gell G,Balázs E

更新日期：2010-02-01 00:00:00

abstract：:Fourteen infectious bronchitis viruses (IBVs) were isolated in Korea between 2001 and 2003 from chickens suspected to be infected with IBVs. The nucleocapsid (N) protein genes of the various IBVs were amplified by reverse transcriptase-polymerase chain reaction (RT-PCR) and were cloned and sequenced, and the nucleotid...

journal_title：Virus genes

authors： Park JY,Pak SI,Sung HW,Kim JH,Song CS,Lee CW,Kwon HM

更新日期：2005-10-01 00:00:00

abstract：:Torque teno viruses (TTVs) are classified into the Anellovirus genus of the Circoviridae family. In addition to TTV isolates, TTV genogroup 3 also includes the 8 virus strains known as SENV-A to H. In this study, the prevalence of TTV group 3 viruses and that of SENV-D and H in particular were determined among the sta...

journal_title：Virus genes

authors： Dencs A,Hettmann A,Szomor KN,Kis Z,Takács M

更新日期：2009-08-01 00:00:00

abstract：:Hepatitis B virus (HBV), a major causative agent of hepatocellular carcinoma (HCC), encodes an oncogenic X protein (HBx) that transcriptionally activates multiple viral and cellular promoters. The present study aimed to identify the specific gene mutation related to the clinical outcome of HCC. Seventy-two HBV-infecte...

journal_title：Virus genes

authors： Fan W,Shi B,Wei H,Du G,Song S

更新日期：2011-04-01 00:00:00

abstract：:Chicken anemia virus (CAV) is the pathogen of chicken infectious anemia. To clarify the driving force in CAV evolution, we have detected positive selection in the structural protein gene VP1 by using maximum-likelihood models. Strong evidence was found that VP1 proteins were subject to the high rates of positive selec...

journal_title：Virus genes

authors： Wang D,Fan W,Han GZ,He CQ

更新日期：2009-04-01 00:00:00

abstract：:The search for retroviruses in human cancer cells has advanced with the discoveries of the retroviral reverse transcriptase, DNA hybridization and sequencing techniques, and polymerase chain reaction (PCR) technology. Each technological advancement has led to a better refinement and a better understanding of latent en...

journal_title：Virus genes

authors： Becker Y

更新日期：1995-02-01 00:00:00

abstract：:Sapoviruses (SaVs) are enteric viruses and have been detected in various mammals. They are divided into multiple genogroups and genotypes based on the entire major capsid protein (VP1) encoding region sequences. In this study, we determined the first complete genome sequences of two genogroup V, genotype 3 (GV.3) SaV ...

journal_title：Virus genes

authors： Oka T,Doan YH,Shimoike T,Haga K,Takizawa T

更新日期：2017-12-01 00:00:00

abstract：:The complete nucleotide sequence of rice tungro spherical virus (RTSV) strain Vt6, originally from Mindanao, the Philippines, with higher virulence to resistant rice cultivars, was determined and compared with the published sequence for the Philippine-type strain A (RTSV-A-Shen). It was reported that RTSV-A was not ab...

journal_title：Virus genes

authors： Isogai M,Cabauatan PQ,Masuta C,Uyeda I,Azzam O

更新日期：2000-01-01 00:00:00

abstract：:Orf virus (ORFV) strain D1701-V, a Parapoxvirus belonging to the family Poxviridae, became attractive as a novel virus vector system that we successfully used for the generation of recombinant vaccines. Therefore, the identification of viral genes involved in host tropisms or immune modulation is of great interest, as...

journal_title：Virus genes

authors： Lacek K,Bauer B,Bieńkowska-Szewczyk K,Rziha HJ

更新日期：2014-08-01 00:00:00

abstract：:Genetic diversity of eight Grapevine leafroll-associated virus 1 (GLRaV-1) isolates recovered from grapevines in three distinct locations in the Czech Republic and Slovakia was characterised by restriction fragment length polymorphism (RFLP) analysis and by sequencing of cloned 540 bp fragment of the heat shock protei...

journal_title：Virus genes

authors： Komínek P,Glasa M,Bryxiová M

更新日期：2005-12-01 00:00:00

abstract：:Emerging pseudorabies virus (PRV) variant has led to frequent outbreaks of PRV infection among Bartha-K61-vaccinated swine population in Chinese swine farms and caused high mortality in pigs of all age since late 2011. Here, we generated a gE/gI-deleted PRV (rPRVXJ-delgI/gE-EGFP) based on PRV variant strain (PRV-XJ) t...

journal_title：Virus genes

authors： Yin Y,Xu Z,Liu X,Li P,Yang F,Zhao J,Fan Y,Sun X,Zhu L

更新日期：2017-08-01 00:00:00

abstract：:A goose parvovirus (GPV) Y strain was isolated from Muscovy ducks in Anhui Province of China. By polymerase chain reaction method, its complete genomic sequence was found to be 5,106 bp in length, consisting of 444-bp inverted terminal repeat, 1,844-bp non-structural protein and 2,199-bp capsid protein (VP) regions. T...

journal_title：Virus genes

authors： Liu HM,Wang H,Tian XJ,Zhang S,Zhou XH,Qi KZ,Pan L

更新日期：2014-02-01 00:00:00

abstract：:Ramu stunt disease of sugarcane was first reported in Papua New Guinea in the mid 1980s. The disease can reduce sugarcane yields significantly and causes severe stunting and mortality in highly susceptible cultivars. The causal agent of Ramu stunt has been investigated but its characterization has not been completed. ...

journal_title：Virus genes

authors： Mollov D,Maroon-Lango C,Kuniata L

更新日期：2016-02-01 00:00:00

abstract：:Currently, virus-based vectors, namely derivatives of the adenovirus, are frequently used in a wide variety of ex vivo or local gene therapeutic applications. However, the efficacy of virus-based vectors in systemic applications is presently still extremely limited. Complex interactions of the various vector types wit...

journal_title：Virus genes

authors： Jönsson F,Kreppel F

更新日期：2017-10-01 00:00:00

abstract：:Bornaviruses (family Bornaviridae) are non-segmented negative-strand RNA viruses. Avian bornaviruses (ABVs), which are causative agents of proventricular dilatation disease, are a genetically diverse group with at least 15 genotypes, including parrot bornaviruses (PaBVs) and aquatic bird bornavirus 1(ABBV-1). Borna di...

journal_title：Virus genes

authors： Sassa Y,Bui VN,Saitoh K,Watanabe Y,Koyama S,Endoh D,Horie M,Tomonaga K,Furuya T,Nagai M,Omatsu T,Imai K,Ogawa H,Mizutani T

更新日期：2015-10-01 00:00:00

abstract：:The reasons for adefovir dipivoxil (ADV) treatment failures appear diverse. Few studies have reported full-length hepatitis B virus (HBV) genome in patients with ADV treatment failures. The patients were from a phase III clinical trial that investigated the antiviral response to ADV in China. Seven patients had increa...

journal_title：Virus genes

authors： Li Y,Zhu M,Guo Y,Chen W,Li G

更新日期：2010-04-01 00:00:00

abstract：:We performed whole genome sequencing of 22 H9N2 avian influenza viruses (AIV) isolated from domestic laying hens on farms between 2005 and 2008, and compared the sequences with viruses previously reported in Asia. A previous study revealed that two antigenically distinct sublineages were established within the MS96 li...

journal_title：Virus genes

authors： Lee CH,Byun SH,Lee YJ,Mo IP

更新日期：2012-08-01 00:00:00

abstract：:Herpesvirus saimiri induces acute lymphomas and leukemias in primates and rabbits. Sequence divergence of the right end unique region of the genome classifies virus strains into three groups (A, B, and C), and previous studies have demonstrated correlation between DNA grouping and oncogenicity. In order to relate diff...

journal_title：Virus genes

authors： Geck P,Whitaker SA,Medveczky MM,Last TJ,Medveczky PG

更新日期：1994-01-01 00:00:00

abstract：:The original version of this article unfortunately contained errors in the "Results" section. ...

journal_title：Virus genes

authors： Guadie D,Tesfaye K,Knierim D,Winter S,Abraham A

更新日期：2019-06-01 00:00:00

abstract：:Nitric oxide (NO) has been shown to suppress Japanese encephalitis virus (JEV) RNA synthesis, viral protein accumulation, and virus release from infected cells. In this article, the potential viral structural proteins as the activators of NO product were studied at the molecular level. First, the genomic region encodi...

journal_title：Virus genes

authors： Chen SO,Fang SH,Shih DY,Chang TJ,Liu JJ

更新日期：2009-02-01 00:00:00